CN106176338A - A kind of anti-aging cosmetics compositions and preparation method thereof - Google Patents

Abstract

The present invention relates to a kind of anti-aging cosmetics compositions, belong to cosmetic field, its active component is combined by Rubus corchorifolius Linn. f. extract, Flos Carthami extract, uva ursi extract, Semen Coicis extract and Herba Schizonepetae extract, and result of the test shows, its anti-aging effects is excellent.

Description

A kind of anti-aging cosmetics compositions and preparation method thereof

Technical field

The present invention relates to cosmetic field, be specifically related to a kind of anti-aging cosmetics compositions and preparation method thereof.

Background technology

Beautiful and youth is the pursuit of women invariability, thus the skin care item with senile-resistant efficacy are the most extensively pushed away High, but, the most of product on market is all made an overstatement, and uses actual effect general, it is contemplated that research one Plant the anti-aging effects skin care item significantly containing natural component.

Rubus corchorifolius Linn. f. (Rubus corchorifolius L.f.), has another name called Fructus Rubi, mountain throwing, milk bubble, spreads seedling bubble, Herba Rubi parvifolii, April bubble, dragon-boat bubble, Fructus Hordei Vulgaris bubble, bubble youngster's thorn, thorn calabash, steamed bread spinach, high foot ripple, there is the supporing yang improving eyesight of arresting seminal emission kidney tonifying, relieving alcoholic intoxication only Yearningly, the effect of removing toxic substances of reducing phlegm, cure mainly suffer from a deficiency of the kidney, pass out semen, the disease such as drunk, erysipelas.Research finds, stilbene constituents that Rubus corchorifolius Linn. f. contains, flower Blue or green glycoside, vitamin and SOD (superoxide dismutase) are respectively provided with significant antioxidation, possibly together with vitamin B1, dimension life Element B2, vitamin E, carotene etc., therefore have higher nutritive value and medical care effect.Verify from Rubus corchorifolius Linn. f. Composition see, flavone compound has blood sugar lowering, blood fat reducing, anti-arrhythmia, antioxidation high efficiency and hypotoxicity, defying age Deng physiologically active.Scopoletin has certain analgesia, antiinflammatory, the effect eliminating the phlegm and relieving asthma.Tea polyphenols has blood pressure lowering, fall blood Fat, mutation, prevention and cure of cardiovascular disease, effect of anti-inflammation, also have elimination free radical, cancer-resisting, anti-lipid peroxy Change and the anti-ageing effect of waiting for a long time.SOD at radioprotective, defying age, prevent the aspects such as tumor from having unique function, add medicine, cosmetic to Product can rise antiinflammatory, anti-aging effects.

Flos Carthami (Carthamus tinctorius L.), another name: red blue flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, it is dried Tubular flower, orange red, floral tube is narrow carefully, and tip 5 splits, and sliver is narrow linear, and flower pesticide yellow is unified into pipe, exceeds outside sliver, its Central authorities have stigma to expose.Have special fragrance, mildly bitter flavor.To spend, length of a film, color be scarlet, the soft person of matter is preferred.Flos Carthami has antioxidation Effect, has antifatigue effect, research display simultaneously, and Carthamus yellow 1100mg/kg mice and matched group (use normal salt Water) compare, swimming time is obviously prolonged, and rate elongation reaches 117.0%, P < 0.01.

Folium Vaccinii vitis-idaeae has another name called Bears Fructus Vitis viniferae, the Bears certain kind of berries (Bearberry), is a kind of plant of Ericaceae Folium Vaccinii vitis-idaeae genus.Folium Vaccinii vitis-idaeae can be cooked For medicinal plants.Uva ursi is the leaf of Folium Vaccinii vitis-idaeae, and it contains Arbutin, and Folium Vaccinii vitis-idaeae have antibacterial effect, is the profit of a kind of gentleness Urine agent, can be used to treat the disease of urinary system.Arbutin can also lack the formation of dermal melanin, has the merit of whitening Effect, and be used in cosmetics.

Semen Coicis (Coix chinensis Tod.), is named again: Semen Coicis, Semen Coicis, NLIUGU, for grass Semen Coicis Kernel.It is cool in nature, sweet in the mouth, light, enters spleen, lung, kidney channel, has effect of diuretic, spleen invigorating, eliminating impediment, clearing away heat and discharging pus.Semen Coicis is rich in egg 8 kinds of aminoacid necessary to white matter, carbohydrate and human body, have the strongest white-skinned face function, can make simultaneously skin become smooth, Fine and smooth.Mineral contained by Semen Coicis have releive, calm shine after the effect of skin, vitamin B group has anti-inflammatory, control oil, protects The effect of wet lock water, Coixol has and prevents tanned, to improve scaly dry skin situation effect, and Semen Coicis fat has promotion new old generation Thank, allow the effect that rough thick wrong skin smooths out.

Herba Schizonepetae (Nepeta cataria L.), another name: fragrant Schizonepeta tenuifolia Briq, line shepherd's purse, Herba Schizonepetae, false Soviet Union, be Labiatae, Herba Schizonepetae Belonging to perennial plant, it contains volatile oil 1.8%, and in oil, main constituent is D-menthone, racemization book lotus ketone, a small amount of dextrorotation Fructus Citri Limoniae Alkene, Herba Schizonepetae extract has inhibitory action to collagenase.

The anti-aging cosmetics that the present invention is researched and developed is combined by Rubus corchorifolius Linn. f., Flos Carthami, uva ursi, Semen Coicis and Herba Schizonepetae just , being proved by effect test, its anti-aging effects is excellent.

Summary of the invention

It is an object of the invention to overcome the defect of prior art, it is provided that a kind of effect significant anti-aging cosmetics combination Thing, its formula consists of:

A phase: Rubus corchorifolius Linn. f. extract 15-20 part, Semen Coicis extract 4-6 part, Flos Carthami extract 6-10 part, uva ursi extract 12-15 part, Herba Schizonepetae extract 2-5 part, hyaluronic acid 10-15 part, spermol ethylhexoate 3-8 part, C16-18 alcohol 12-15 Part, glycerol 3-12 part, deionized water 150-200 part；

B phase: American Avocado Tree oil 6-10 part, dimethicone 30-50 part, Magnesium Ascorbyl Phosphate 6-10 part, Adeps Bovis seu Bubali resin 15-18 Part, carbomer 12-15 part, Radix Oenotherae erythrosepalae oil 8-10 part, Herba Salviae Japonicae essential oil 1-5 part, lanoline 15-20 part, octyldodecanol 12- 14 parts；

Preservative, essence are appropriate.

Preferably, its formula consists of:

A phase: Rubus corchorifolius Linn. f. extract 18 parts, Semen Coicis extract 5 parts, Flos Carthami extract 10 parts, uva ursi extract 15 parts, Herba Schizonepetae Extract 2 parts, hyaluronic acid 12 parts, spermol ethylhexoate 6 parts, C16-18 alcohol 12 parts, glycerol 10 parts, deionized water 200 Part；

B phase: American Avocado Tree oil 8 parts, dimethicone 40 parts, Magnesium Ascorbyl Phosphate 8 parts, Adeps Bovis seu Bubali resin 16 parts, carbomer 12 Part, Radix Oenotherae erythrosepalae oil 10 parts, Herba Salviae Japonicae essential oil 4 parts, lanoline 18 parts, octyldodecanol 12 parts.

Described Rubus corchorifolius Linn. f. extract, Flos Carthami extract, uva ursi extract, Semen Coicis extract and Herba Schizonepetae extract can pass through Water commonly used in the art carries or prepared by the method for alcohol extraction.

Such as, the preparation method of described Rubus corchorifolius Linn. f. extract, Flos Carthami extract and uva ursi extract is: by Rubus corchorifolius Linn. f., Flos Carthami Or uva ursi presses solid-liquid ratio 1:(10-15) add distilled water and extract 1-2h in 80 DEG C, in triplicate, filter, merging filtrate, decompression Concentrate, with the 90% ethanol precipitate with ethanol 3 times of 6-8 times of volume, filter, precipitation is dry, to obtain final product；

The preparation method of described Semen Coicis extract and Herba Schizonepetae extract is: after adding petroleum ether degreasing in Semen Coicis or Herba Schizonepetae Solid-liquid ratio 1:(10-15 is pressed with 60% ethanol) extract 0.5-1h in 50 DEG C, repeat to extract three times, merging filtrate, in 90 DEG C of rotations Evaporate to obtain thick paste, dry, pulverize, to obtain final product.

Invention also provides the preparation method of above-mentioned anti-aging cosmetics compositions, its operating procedure is:

(1) by uniform for each for A phase component heated and stirred；

(2) by uniform for each for B phase component heated and stirred；

(3) by A phase and B phase mix homogeneously, add preservative and essence, stir, cooling, to obtain final product.

The heating-up temperature of described A phase and B phase is preferably 80-85 DEG C.

The active component of the anti-aging cosmetics compositions of the present invention is carried by Rubus corchorifolius Linn. f. extract, Flos Carthami extract, uva ursi Taking thing, Semen Coicis extract and Herba Schizonepetae extract to combine, result of the test shows, its anti-aging effects is excellent.

Detailed description of the invention

The preparation of plant extract

Rubus corchorifolius Linn. f., Flos Carthami or uva ursi are pressed solid-liquid ratio 1:12 and adds distilled water in 80 DEG C of extraction 1.5h, in triplicate, mistake Filter, merging filtrate, concentrating under reduced pressure, with the 90% ethanol precipitate with ethanol 3 times of 7 times of volumes, filter, precipitation is dry, obtain Rubus corchorifolius Linn. f. respectively and carry Take thing, Flos Carthami extract and uva ursi extract；Feed liquid is pressed with 60% ethanol after adding petroleum ether degreasing in Semen Coicis or Herba Schizonepetae Extract 1h than 1:15 in 50 DEG C, repeat to extract three times, merging filtrate, obtain thick paste in 90 DEG C of rotary evaporations, dry, pulverize, respectively Obtain Semen Coicis extract and Herba Schizonepetae extract.

Embodiment 1

Raw material is taken by following composition:

A phase: Rubus corchorifolius Linn. f. extract 15 parts, Semen Coicis extract 4 parts, Flos Carthami extract 7 parts, uva ursi extract 12 parts, Herba Schizonepetae Extract 2 parts, hyaluronic acid 12 parts, spermol ethylhexoate 4 parts, C16-18 alcohol 12 parts, glycerol 5 parts, deionized water 150 Part；

B phase: American Avocado Tree oil 6 parts, dimethicone 30 parts, Magnesium Ascorbyl Phosphate 6 parts, Adeps Bovis seu Bubali resin 15 parts, carbomer 14 Part, Radix Oenotherae erythrosepalae oil 8 parts, Herba Salviae Japonicae essential oil 2 parts, lanoline 20 parts, octyldodecanol 12 parts；

Each component of A phase and B phase is uniform respectively at 80 DEG C of heated and stirred, then by both mix homogeneously, add anticorrosion Agent and essence, stir, cooling, to obtain final product.

Embodiment 2

Raw material is taken by following composition:

A phase: Rubus corchorifolius Linn. f. extract 18 parts, Semen Coicis extract 5 parts, Flos Carthami extract 8 parts, uva ursi extract 13 parts, Herba Schizonepetae Extract 4 parts, hyaluronic acid 13 parts, spermol ethylhexoate 6 parts, C16-18 alcohol 14 parts, glycerol 8 parts, deionized water 180 Part；

B phase: American Avocado Tree oil 8 parts, dimethicone 40 parts, Magnesium Ascorbyl Phosphate 8 parts, Adeps Bovis seu Bubali resin 16 parts, carbomer 14 Part, Radix Oenotherae erythrosepalae oil 9 parts, Herba Salviae Japonicae essential oil 3 parts, lanoline 18 parts, octyldodecanol 13 parts；

Each component of A phase and B phase is uniform respectively at 80 DEG C of heated and stirred, then by both mix homogeneously, add anticorrosion Agent and essence, stir, cooling, to obtain final product.

Embodiment 3

Raw material is taken by following composition:

A phase: Rubus corchorifolius Linn. f. extract 20 parts, Semen Coicis extract 6 parts, Flos Carthami extract 10 parts, uva ursi extract 15 parts, Herba Schizonepetae Extract 5 parts, hyaluronic acid 15 parts, spermol ethylhexoate 8 parts, C16-18 alcohol 15 parts, glycerol 12 parts, deionized water 200 Part；

B phase: American Avocado Tree oil 10 parts, dimethicone 50 parts, Magnesium Ascorbyl Phosphate 10 parts, Adeps Bovis seu Bubali resin 18 parts, carbomer 15 Part, Radix Oenotherae erythrosepalae oil 10 parts, Herba Salviae Japonicae essential oil 5 parts, lanoline 20 parts, octyldodecanol 14 parts；

Each component of A phase and B phase is uniform respectively at 85 DEG C of heated and stirred, then by both mix homogeneously, add anticorrosion Agent and essence, stir, cooling, to obtain final product.

Embodiment 4:

The Antisenility Experiment of Fructus Lycii defying age extract:

Taking Aged Mice 40, be randomly divided into 4 groups, often group 10, gavages the anti-aging cosmetics group of embodiment 1-3 respectively Five Plant Extracts mixture 100mg/kg in compound, normal saline 0.5mL/ only, under equal conditions, feed continuous 30 My god, it is administered eye socket blood sampling in latter 2 hours for the last time, measures SOD and LPO content, take tail eyelash mensuration HO-Pro after putting to death mice and contain Amount.Result is as shown in table 1:

Table 1 anti-aging cosmetics compositions thing is on Aged Mice SOD, the impact of LPO, HO-PRO

	SOD(u/ghb)	LPO(mol/ml)	HO-Pro(mg/5mg)
				Normal saline group	1311	8.43	3.27
Embodiment 1	2612	4.11	5.21
				Embodiment 2	2633	4.01	5.00
Embodiment 3	2642	4.18	5.02

Meanwhile, taking mice 40, be randomly divided into 4 groups, often group 10, gavages the anti-aging cosmetics of embodiment 1-3 respectively Five Plant Extracts mixture 100mg/kg in compositions, normal saline 0.5mL/ only, under equal conditions, feed continuous 30 My god, carry out endurance mensuration respectively, according to 15% heavy burden of Mouse Weight, in depth of water 60cm, the water went swimming of water temperature 22 DEG C, with mice The no longer floating that sinks under water is index, measures their swimming time.Result is as shown in table 2:

The impact on mice swimming time of the table 2 anti-aging cosmetics compositions

	Normal saline group	Embodiment 1	Embodiment 2	Embodiment 3
					Swimming time (s)	46.8	88.2	91.3	99.1

Result shows, the anti-aging cosmetics compositions of the present invention can significantly reduce LPO level in Aged Mice serum, Improve SOD activity in Aged Mice erythrocyte, mice can be extended simultaneously and improve endurance, extend mice swimming time, thus can Effectively remove the infringement that interior free yl is caused, thus reduce generation and the slow down aging of disease.

Claims (5)

1. an anti-aging cosmetics compositions, it is characterised in that its formula consists of:

A phase: Rubus corchorifolius Linn. f. extract 15-20 part, Semen Coicis extract 4-6 part, Flos Carthami extract 6-10 part, uva ursi extract 12-15 Part, Herba Schizonepetae extract 2-5 part, hyaluronic acid 10-15 part, spermol ethylhexoate 3-8 part, C16-18 alcohol 12-15 part, glycerol 3-12 part, deionized water 150-200 part；

B phase: American Avocado Tree oil 6-10 part, dimethicone 30-50 part, Magnesium Ascorbyl Phosphate 6-10 part, Adeps Bovis seu Bubali resin 15-18 part, card Ripple nurse 12-15 part, Radix Oenotherae erythrosepalae oil 8-10 part, Herba Salviae Japonicae essential oil 1-5 part, lanoline 15-20 part, octyldodecanol 12-14 part；

Preservative, essence are appropriate.

Anti-aging cosmetics compositions the most according to claim 1, it is characterised in that its formula composition is preferably For:

A phase: Rubus corchorifolius Linn. f. extract 18 parts, Semen Coicis extract 5 parts, Flos Carthami extract 10 parts, uva ursi extract 15 parts, Herba Schizonepetae is extracted Thing 2 parts, hyaluronic acid 12 parts, spermol ethylhexoate 6 parts, C16-18 alcohol 12 parts, glycerol 10 parts, deionized water 200 parts；

B phase: American Avocado Tree oil 8 parts, dimethicone 40 parts, Magnesium Ascorbyl Phosphate 8 parts, Adeps Bovis seu Bubali resin 16 parts, carbomer 12 parts, the moon See grass oil 10 parts, Herba Salviae Japonicae essential oil 4 parts, lanoline 18 parts, octyldodecanol 12 parts.

Anti-aging cosmetics compositions the most according to claim 1 and 2, it is characterised in that

The preparation method of described Rubus corchorifolius Linn. f. extract, Flos Carthami extract and uva ursi extract is: Rubus corchorifolius Linn. f., Flos Carthami or uva ursi are pressed Solid-liquid ratio 1:(10-15) add distilled water in 80 DEG C extract 1-2h, in triplicate, filter, merging filtrate, concentrating under reduced pressure, use 6-8 90% ethanol precipitate with ethanol of times volume 3 times, filters, and precipitation is dry, to obtain final product；

The preparation method of described Semen Coicis extract and Herba Schizonepetae extract is: use after adding petroleum ether degreasing in Semen Coicis or Herba Schizonepetae Solid-liquid ratio 1:(10-15 pressed by 60% ethanol) extract 0.5-1h in 50 DEG C, repeat to extract three times, merging filtrate, rotate in 90 DEG C and steam Send out to obtain thick paste, dry, pulverize, to obtain final product.

4. according to the preparation method of the anti-aging cosmetics compositions described in any one of claim 1-3, it is characterised in that its behaviour As step it is:

(1) by uniform for each for A phase component heated and stirred；

(2) by uniform for each for B phase component heated and stirred；

(3) by A phase and B phase mix homogeneously, add preservative and essence, stir, cooling, to obtain final product.

Preparation method the most according to claim 3, it is characterised in that the heating-up temperature of described A phase and B phase is preferably 80- 85℃。