CN106166272A - A kind of Chinese medicine composition treating necrosis - Google Patents

A kind of Chinese medicine composition treating necrosis Download PDF

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CN106166272A
CN106166272A CN201610725497.2A CN201610725497A CN106166272A CN 106166272 A CN106166272 A CN 106166272A CN 201610725497 A CN201610725497 A CN 201610725497A CN 106166272 A CN106166272 A CN 106166272A
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eupolyphaga
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黄连启
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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

A kind of Chinese medicine composition treating necrosis, it is characterized in that, including endo-medicine and external used medicine, wherein said endo-medicine is made up of the component of following weight: eupolyphaga 69 grams, Rhizoma Wenyujin Concisum 39 grams, Hirudo 69 grams, Auricularia 25 30 grams, Radix Paeoniae Rubra 69 grams, Herba Asari 3 grams, Radix Notoginseng powder 3 grams, Radix Cyathulae 9 15 grams;Described external used medicine is made up of the component of following weight: eupolyphaga 15 25 grams, Hirudo 20 30 grams, Auricularia 25 30 grams, Herba Asari 12 15 grams, Radix Notoginseng powder 69 grams, the Fructus Crotonis 23 that deoils, Flos Lonicerae 20 25 grams.The present invention uses Chinese herbal medicine formula, material to be easy to get, and preparation method is simple, oral administration and externally, and therapeutic effect is good, and price is low, instant effect, and curative effect is reliable, with system with without obvious adverse reaction and side effect.

Description

A kind of Chinese medicine composition treating necrosis
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition treating necrosis.
Background technology
Necrosis one disease is thromboangiitis obliterans alleged in modern medicine, and primary disease is thought an effective reinforcement by motherland's medical science Arteries and veins is got involved, the chronic disease that apotelus necrosis comes off, and is also the scope of middle gangrene of finger or toe.Its cause of disease all feelings will internal injury, temper is not strong, Liver and kidney Not enough, cold-damp is attacked, wound stimulates so that it is venation numbness plug, QI and blood being obstructed, extremity are that the cold main spasm in end of all sun stagnates, acra Easily by numbness plug, failing preventing and treating time long, QI and blood is retarded by silt then ZIJING, podomere can not QI and blood warm moisten foster.Then feel cold numb, pale, step Carry out inconvenience, therefore just refer to joint necrosis.The traditional Chinese medical science is point cold-dampness type, blood stasis type, heat-toxin type, QIXUELIANGXU type, renal deficiency type, typing in dialectical Treat.According to characteristics of incidence, use to nourish blood and seek, the drug regimen of relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and clearing away heat.Prove through long-term practice Effective herbal composite is provided for treatment necrosis.
Summary of the invention
The technical problem to be solved is to provide a kind of combination simple, the Chinese drug-treated group of eutherapeutic treatment necrosis Compound.
The technical problem to be solved realizes by the following technical solutions:
A kind of Chinese medicine composition treating necrosis, including endo-medicine and external used medicine, wherein said endo-medicine be by The component of following weight is made: eupolyphaga 6-9 gram, Rhizoma Wenyujin Concisum 3-9 gram, Hirudo 6-9 gram, Auricularia 25-30 gram, Radix Paeoniae Rubra 6-9 gram, thin Pungent 3 grams, Radix Notoginseng powder 3 grams, Radix Cyathulae 9-15 gram;The preparation method of above-mentioned endo-medicine is: by eupolyphaga, Rhizoma Wenyujin Concisum, Hirudo, black wood Ear, Radix Paeoniae Rubra, Herba Asari and Radix Cyathulae added water no in being placed in marmite powder, with slow fire boiling after soaking 60-90 minute, after boiling again Continue and boil 15 minutes, liquid 200 milliliters of every time boiling medicine, put into Radix Notoginseng powder and stir evenly, every day 2 times, for oral administration;
Described external used medicine is made up of the component of following weight: eupolyphaga 15-25 gram, Hirudo 20-30 gram, Auricularia 25- 30 grams, Herba Asari 12-15 gram, Radix Notoginseng powder 6-9 gram, deoil Fructus Crotonis 2-3 grain (broken), Flos Lonicerae 20-25 gram;The system of above-mentioned external used medicine Preparation Method is: said medicine being placed in marmite and add water in right amount, decoct about 12 minutes, filtrate 1200-1500 milliliter, temperature is fitted Preferably, pour foot bath in basin into, soak 12 minutes every time, the most once.
Effect: promoting blood circulation to remove blood stasis, the logical pain relieving of temperature, expand blood vessel, environment spasm.
Study mechanism: eupolyphaga breaks congestion abdominal mass;Hirudo blood circulation promoting and blood stasis dispelling thrombolytic, releases arteriospasm;Auricularia contains abundant Protein, trace element, nicotinic acid, injection Vitamin B_6, thrombolytic blood sugar lowering, expand blood vessel, nutrition blood is sought, and antioxidation improves Tissue Blood Confession, repairing ulcer and slough;It is stagnant that Radix Paeoniae Rubra expands the logical heap soil or fertilizer over and around the roots of blood vessel;Pseudo-ginseng blood-circulation-invigovating, analgesic hemostatic;Rhizoma Wenyujin Concisum, Herba Asari temperature pain relieving;River Radix Achyranthis Bidentatae the meridian dredging, draws the through sick institute of all medicines.
The present composition has carried out substantial amounts of animal acute toxicity test, long-term toxicity test for animals and treatment disease A large amount of clinical trials, the use link that this medicine puts into treatment disease provides science and objective foundation.Its test method As follows with result of the test:
(1) medicinal liquid for oral administration preparing the present invention carries out animal acute toxicity test:
Medicine: the crude drug used in the present invention is commercially available from common Chinese shop, its specification meets country's Chinese crude drug mark Accurate.
Experimental animal: white mice, body weight randomly chooses in about 50g, male and female, market buys.
Method and result: take white mice 10, hungry about 20 hours, fill for 5 times by every every natural gift and feed 50ml, feed continuously One week, observing 10 days, mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical application agent Amount safety.
(2) medicinal liquid for oral administration preparing the present invention carries out long-term toxicity test for animals:
Experimental animal: rat, body weight randomly chooses in 120-130g, male and female, market buys.
Method and result: take rat 20, be divided into 2 groups, often group 10, and wherein the 1st group as administration group, every by every Filling for they 2 times and feed, each 5-10ml, the 2nd group of diet as a control group, once a day, fills continuously and feeds 90 days, survey body Weight, is administered latter 24 hours sacrificed by decapitation in last, surveys blood, routine urinalysis, liver function, renal function, cores, the internal organs such as kidney, sees Examining the change of tissue morphology, observe the effect of dosage, observe diet, movable change, experiment proves administration group and matched group ratio Relatively without notable change, equal non-toxic reaction, it is a kind of safe drugs.
The invention has the beneficial effects as follows: the present invention uses Chinese herbal medicine formula, material to be easy to get, preparation method is simple, outside taking orally With, therapeutic effect is good, and price is low, instant effect, and curative effect is reliable, with system with without obvious adverse reaction and side effect.
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and be easy to understand with effect, below knot Close specific embodiment, the present invention is expanded on further.
Embodiment 1
A kind of Chinese medicine composition treating necrosis, including endo-medicine and external used medicine, wherein said endo-medicine be by The component of following weight is made: eupolyphaga 6 grams, Rhizoma Wenyujin Concisum 3 grams, Hirudo 6 grams, Auricularia 25 grams, Radix Paeoniae Rubra 6 grams, Herba Asari 3 grams, Radix Notoginseng 3 grams of powder, Radix Cyathulae 9 grams;The preparation method of above-mentioned endo-medicine is: by eupolyphaga, Rhizoma Wenyujin Concisum, Hirudo, Auricularia, Radix Paeoniae Rubra, Herba Asari Add water in being placed in marmite with Radix Cyathulae not powder, with slow fire boiling after soaking 60-90 minute, renew after boiling and boil 15 minutes, Boil medicine liquid 200 milliliters every time, put into Radix Notoginseng powder and stir evenly, every day 2 times, for oral administration;
Described external used medicine is made up of the component of following weight: eupolyphaga 15 grams, Hirudo 20 grams, Auricularia 25 grams, Herba Asari 12 grams, Radix Notoginseng powder 6 grams, deoil Fructus Crotonis 2 (broken), Flos Lonicerae 20 grams;The preparation method of above-mentioned external used medicine is: by said medicine It is placed in marmite and adds water in right amount, decoct about 12 minutes, filtrate 1200-1500 milliliter, proper temperature, pour foot bath in basin into, every time Soak 12 minutes, the most once.
Embodiment 2
A kind of Chinese medicine composition treating necrosis, including endo-medicine and external used medicine, wherein said endo-medicine be by The component of following weight is made: eupolyphaga 9 grams, Rhizoma Wenyujin Concisum 9 grams, Hirudo 9 grams, Auricularia 30 grams, Radix Paeoniae Rubra 9 grams, Herba Asari 3 grams, Radix Notoginseng 3 grams of powder, Radix Cyathulae 15 grams;The preparation method of above-mentioned endo-medicine is: by eupolyphaga, Rhizoma Wenyujin Concisum, Hirudo, Auricularia, Radix Paeoniae Rubra, Herba Asari Add water in being placed in marmite with Radix Cyathulae not powder, with slow fire boiling after soaking 60-90 minute, renew after boiling and boil 15 minutes, Boil medicine liquid 200 milliliters every time, put into Radix Notoginseng powder and stir evenly, every day 2 times, for oral administration;
Described external used medicine is made up of the component of following weight: eupolyphaga 25 grams, Hirudo 30 grams, Auricularia 30 grams, Herba Asari 15 grams, Radix Notoginseng powder 9 grams, deoil Fructus Crotonis 3 (broken), Flos Lonicerae 25 grams;The preparation method of above-mentioned external used medicine is: by said medicine It is placed in marmite and adds water in right amount, decoct about 12 minutes, filtrate 1200-1500 milliliter, proper temperature, pour foot bath in basin into, every time Soak 12 minutes, the most once.
Model case:
1. Huang Shi, female, 74 years old, people from Dancheng, Henan, right crus of diaphragm was numb, and intermittent slope row, rear calcaneodynia, purple is the most shrivelled, to Zhengzhou Provincial hospital is diagnosed as vasculitis through Doppler, with the recovery from illness in nearly 3 months of the embodiment of the present invention 1 Drug therapy.
2. Lee so-and-so, man, 35 years old, people from Jieshou City, Anhui, there is cold extremities in right crus of diaphragm, pale, tranquillization ache, night is many very, rear three Toe occurs dark violet.It is diagnosed as vasculitis, with the recovery from illness in nearly 4 months of the embodiment of the present invention 1 Drug therapy to hospital general of Nanjing Military Command.
3. temperature so-and-so, man, 83 years old, people from Jieshou City, Anhui, right crus of diaphragm performance numbness, Shi Leng, intermittent slope row, continue tranquillization Pain, night, weight, dark violet, and slight gangrene occurs in the second toe, and Medical University Of Anhui is diagnosed as vasculitis, by the embodiment of the present invention 2 Drug therapy recovery from illness in nearly 3 months.
The ultimate principle of the present invention and principal character and advantages of the present invention have more than been shown and described.The technology of the industry Personnel, it should be appreciated that the present invention is not restricted to the described embodiments, simply illustrating this described in above-described embodiment and description The principle of invention, without departing from the spirit and scope of the present invention, the present invention also has various changes and modifications, and these become Change and improvement both falls within scope of the claimed invention.Claimed scope by appending claims and Equivalent defines.

Claims (3)

1. the Chinese medicine composition treating necrosis, it is characterised in that include endo-medicine and external used medicine, wherein said for oral administration Medicine is made up of the component of following weight: eupolyphaga 6-9 gram, Rhizoma Wenyujin Concisum 3-9 gram, Hirudo 6-9 gram, Auricularia 25-30 gram, Radix Paeoniae Rubra 6-9 gram, Herba Asari 3 grams, Radix Notoginseng powder 3 grams, Radix Cyathulae 9-15 gram;
Described external used medicine is made up of the component of following weight: eupolyphaga 15-25 gram, Hirudo 20-30 gram, Auricularia 25-30 gram, Herba Asari 12-15 gram, Radix Notoginseng powder 6-9 gram, deoil Fructus Crotonis 2-3 grain, Flos Lonicerae 20-25 gram.
A kind of Chinese medicine composition treating necrosis the most according to claim 1, it is characterised in that the system of above-mentioned endo-medicine Preparation Method is: added water in eupolyphaga, Rhizoma Wenyujin Concisum, Hirudo, Auricularia, Radix Paeoniae Rubra, Herba Asari and Radix Cyathulae are placed in marmite no powder, leaching With slow fire boiling after steeping 60-90 minute, renew after boiling and boil 15 minutes, liquid 200 milliliters of every time boiling medicine, put into Radix Notoginseng powder and stir evenly, Every day 2 times, for oral administration.
A kind of Chinese medicine composition treating necrosis the most according to claim 1, it is characterised in that the system of above-mentioned external used medicine Preparation Method is: said medicine is placed in marmite and adds water in right amount, decoct 12 minutes, filtrate 1200-1500 milliliter, proper temperature, falls Foot bath in engagement, soaks 12 minutes every time, the most once.
CN201610725497.2A 2016-08-25 2016-08-25 A kind of Chinese medicine composition treating necrosis Pending CN106166272A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040058983A1 (en) * 2000-08-18 2004-03-25 Heikki Vuorela Plan-derived and synthetic phenolic compounds and plant extracts, effective in the treatment and prevention of chlamydial infections
CN103585410A (en) * 2013-10-18 2014-02-19 尹静 Traditional Chinese medicine composition for treating angitis
CN104027775A (en) * 2014-01-15 2014-09-10 解程 Traditional Chinese medicine for treating thromboangiitis obliterans

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040058983A1 (en) * 2000-08-18 2004-03-25 Heikki Vuorela Plan-derived and synthetic phenolic compounds and plant extracts, effective in the treatment and prevention of chlamydial infections
CN103585410A (en) * 2013-10-18 2014-02-19 尹静 Traditional Chinese medicine composition for treating angitis
CN104027775A (en) * 2014-01-15 2014-09-10 解程 Traditional Chinese medicine for treating thromboangiitis obliterans

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