CN106166128A - Exempt from water sterilizing abluent - Google Patents

Exempt from water sterilizing abluent Download PDF

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Publication number
CN106166128A
CN106166128A CN201610719354.0A CN201610719354A CN106166128A CN 106166128 A CN106166128 A CN 106166128A CN 201610719354 A CN201610719354 A CN 201610719354A CN 106166128 A CN106166128 A CN 106166128A
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abluent
skin
water sterilizing
water
exempt
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成钢
成进学
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Nantong Snakes Treating Institute
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Nantong Snakes Treating Institute
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Priority to CN201610719354.0A priority Critical patent/CN106166128A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/24Phosphorous; Compounds thereof
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    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
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    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29Titanium; Compounds thereof
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993Derivatives containing from 2 to 10 oxyalkylene groups
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
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    • A61K8/733Alginic acid; Salts thereof
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    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8129Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
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    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

The invention discloses one and exempt from water sterilizing abluent, it is belonging to little chemical products detergent liquid preparation production technical field, water sterilizing abluent is exempted from by sodium alginate carbamide skin moistening anticracking, the anti-skin peeling of Herb Gynostemmae Pentaphylli nanometer silver eczema of chapping exempts from water sterilizing abluent, Aloe tea tree oil ZnOw ZnOw cleans the anti-pruritus of clean skin and exempts from water sterilizing abluent, middle carbon alcohol TiO2Decontamination skin-protection exempts from water sterilizing abluent composition.For special work post personnel such as earthquake, mud-rock flow, tourism, field work, geology detecting, driver, paint, in hydropenia, keep a public place clean for hands and whole skin mud, greasy dirt, the cleaning of dirt under anhydrous condition, sterilize, sterilize, skin protection, the anti-xerosis cutis of skin moistening, dirty bits, peel, chap, pruritus, eczema, make skin moisturizing, smooth glossy elasticity, lasting fragrance, feel the most comfortable.

Description

Exempt from water sterilizing abluent
Technical field:
The invention discloses one and exempt from water sterilizing abluent, be belonging to little chemical products abluent configuration production technology Field.
Background technology:
At special work post personnel and vapour such as the tourism field work of earthquake mud-rock flow countryside, geology detecting personnel, paint chemical industry Car driver is used for removing hand mud, greasy dirt and other dirts, can clean protection skin with sterilizing, prevent skin simultaneously Skin is coarse, is dried decortication, chaps;Particularly suitable earthquake, mud-rock flow, mine, the operation of desert, down-hole and machine repair personnel, and arid Exempt from the personnel of water, water-deficient area, hand decontamination, clean hand skin, sterilizing strong detergency, make skin smooth, be rich in light The elastic lasting fragrance in pool, avirulence, non-stimulated to skin, feel the most comfortable, use safety and stability good, have no side effect;Make Used time only needs an abluent, smoothens whole for hands, rubbing repeatedly, make booty with liquid film remove, practical and convenient, consumption is few, easy In carrying, Non-water washing, with rear skin without being dried rubescent, pruritus malaise symptoms, sterilizing, skin moistening effect of anti-cracking is notable, experiment Study 6h after degerming rate reaches 96.59% use and still have the antibacterial continuity effect of excellence.
Summary of the invention:
It is an object of the invention to provide one and exempt from water sterilizing abluent, the technical solution of the present invention is:
1, one exempts from water sterilizing abluent, it is characterized in that: described sodium alginate carbamide skin moistening anticracking is exempted from water sterilization and disappeared Poison abluent, is made into % by following masses proportioning
Preparation method:
(1) in enamel reaction still, addition sodium alginate is warming up to 70 DEG C mix cold stirring 1h with distilled water after, adds poly- Vinyl alcohol dissolves, stirs, is warming up to 90~95 DEG C, reacts 1h, is completely dissolved as clear solution.
(2) material (1) is cooled to 40~50 DEG C, is slowly added to sodium lauryl sulphate and carbamide successively (first with a little Water dissolution), cocoanut oil diethan olamide, carboxyl methyl cellulose sodium, acetylated lanolin and white oil etc..
(3) when room temperature is down to by material (2), it is sequentially added into glycerol, sodium tripolyphosphate (first dissolving), trifluoro three by little water Ethyl chloride, to antelope yl benzoic acid methyl ester, be eventually adding rose essence, after all material adds, be further continued for stir 30min, mixing Uniformly, put in storage tank, place aging, finished product can be packed to obtain.
The above polyvinyl alcohol average degree of polymerization be 500 for detergent viscosity reinforcing agent+sodium dialkyl sulfate for cloudy from Sub-surface activating agent: cocoanut oil diethan olamide is nonionic surfactant, strengthens washability;Carboxyl methyl cellulose Sodium is viscosity-controlling agent;Carbamide is solubilizing agent;The effect of acetylated lanolin is to add ester, lubrication;White oil, glycerol are skin moistening Agent: sodium tripolyphosphate is builder: be anticorrosion, antibacterial to antelope yl benzoic acid methyl ester;Formaldehyde is sterilization, mould microbial inoculum;Rose Essence is fumet;Second alcohol and water is solvent.
This product is used for decontamination, sterilization, and can make skin smooth, high resilience, have certain skin protection to dry and cracked with degreased skin Effect.
During use, this product being squeezed in injury several, rubbing can be not required to rinse with water for several times repeatedly.This product formula closes Reason, strong detergency, lasting fragrance, avirulence, non-stimulated to skin, with after feel smooth comfortable;Finished product, with plastic bottle packing, makes With and easy to carry.
(2), one exempt from water sterilizing abluent, it is characterized in that: the described anti-skin peeling of Herb Gynostemmae Pentaphylli nanometer silver is chapped wet Rash exempts from water sterilizing abluent, is made into % by following mass parts
A phase
Herb Gynostemmae Pentaphylli extract 1.5-4.5;Tea saponin 2-6;
Polysorbate60 0.5-1.5;
B phase
Glycyrrhizic acid 1-3;Selenium-rich deodorize vegetable oil 2-6;
C phase
Polyvinyl alcohol 2-6;Polyethylene adjoins pyrrolidone 0.7-2.1;
D phase
Polyethylene Glycol 3-9;Octadecanol 1.5-4.5;
Compound glycerin 3-9;Spice 0.4-1.2;
Water adds to 100%;
Preparation method:
(1), after A group solid material being dissolved in water, B group, together stirring and dissolving 40min~1h are added.
(2) progressively being heated by solution (1), in 5~15min, temperature reaches 90~95 degrees Celsius.
(3), after solid particle is all uniformly dissolved, the polyvinyl alcohol of C group, polyvinylpyrrolidone and the poly-second of D group are added Glycol, octadecanol and compound glycerin, fully react.
(4) after material is uniform faint yellow emulsion, cooling down to 40~45 DEG C, add the nanometer silver wide spectrum in D group and resist Microbial inoculum, spice and water, stir, at normal temperatures Chen Hua 8h, in emulsion form, is finished product, and A group is natural surfactant, Use tea saponin and the anion of theme composition replacement synthesis, the nonionic surfactant that Herb Gynostemmae Pentaphylli extract is detergent liquid multiple Part system.
Tea saponin be extract from Oil-tea-cake pure natural surfactant, there is efficient emulsifying, disperse, the table such as moisten Face activity, pharmacology, there is anti-inflammatory analgesic action.
The chemical constitution that the oldest point of Herb Gynostemmae Pentaphylli extract is Herb Gynostemmae Pentaphylli and has natural surfactant, safety non-toxic, Can skin care, also have obvious dirt-removing power and reduce water surface tension ability, osmosis can be strengthened.
B group is film former, uses polyvinyl alcohol and polyvinylpyrrolidone compound system, makes film formation time reduce, shortens Wash one's hands the decontamination time, and can effectively prevent the dirt reprecipitation to skin.
D group is additive, be for strengthen skin moistening, be incubated, sterilize, sterilize and the needs of commodity performance and configure and various former Material.
This product for skin decontamination, sterilize, deodorize and skin care, the most also can prevent and treat chapped skin, for decortication, wet The inflammation such as rash also have preventive and therapeutic action.Being particularly well-suited to occupation workman, especially mine, down-hole, geological prospecting, desert are made The personnel of industry, machine repair personnel and drought and water-scarce area.
This product formula is advanced, replaces the decontamination based on synthetic multiple with the compound system of two kinds of natural surfactants Combo is divided, comprehensive strong detergency, and nontoxic, nonirritant, uses safety.
(3) one exempts from water sterilizing abluent, it is characterized in that: described Aloe tea tree oil ZnOw ZnOw cleans clean The anti-pruritus of skin exempts from water sterilizing abluent, is made into % by following masses proportioning
Preparation method:
(1) in reaction pot added a cover by rustless steel, add pure water, Carboxypolymethylene ultrez10 is divided 3~5 times and be slowly added in pure water, limit Add limit stirring, with 80~100r/min;The speed mechanical stirring 150min of min, fully dispersed obtains uniform cloudy dispersion, Standing overnight, the most swelling, gained is as solution A.
(2) in reaction pot added a cover by another rustless steel, add part ethanol, be subsequently adding 5-chlorine 2-(the double chlorobenzene oxygen of 2.4-) Phenol (i.e. triclosan), mixed dissolution, the speed mechanical with 50~80r/min stirs 10min, until liquid clear, gained As second liquid, airtight preservation, standby.
(3) being poured in solution A by second liquid, and add remaining ethanol, the speed with 50~80r/min stirs 30min, mixed Close uniformly.
(4) in material (3), skin protectant, tea tree oil, wetting agent, cosolvent it are sequentially added into, ZnOw ZnOw, mixing Dissolve, be sufficiently stirred for 10min to the most dispersed with the speed of 80~100r/min, add PH regulator, regulation PH to 6.7~ 8.7, add essence, supplement pure water and be stirred for 20min after enough, get product.
Ethanol is solvent, has disinfective action simultaneously.ZnOw ZnOw is high-efficiency broad spectrum antibacterial, and tea tree oil is for carrying Body, has and comprises the effect that can eliminate ethanol abnormal smells from the patient.
Carboxypolymethylene ultrez10 is thickening agent, can strengthen the chloro-2-of clathration-5 (the double chlorobenzene oxygen of the 2.4-) phenol of tea tree oil simultaneously, be commonly called as Triclosan or triclosan, for wide spectrum disinfective agent.
Cosolvent can be nonionic surfactant, such as tween 20, has hydrophilic and oleophilic function, contributes to including Thing is common molten with solvent.
PH regulator preferably uses the regulator of skin-friendly, such as triethanolamine.
Wetting agent can be hyaluronic acid, lactic acid, glycerol etc., is wherein preferred with glycerol.
Skin protectant can be vitamin E, aloe etc. therein one or more.
In the case of this product can be not required to water flushing, skin hand is carried out sterilization.It is applicable to hospital, family etc. many Plant place, be particularly suited for field usage.
This product technique is simple, and equipment investment is few, it is easy to large-scale production;Use macromolecule inclusion technique, eliminate highly concentrated Degree ethanol obtains sharp aroma;In raw material, chlorine-containing disinfectant consumption is few, little to skin side-effects, non-stimulated, is dried by rear nothing, sends out The malaise symptoms such as red, pruritus;Easy to use, effect is notable, and degerming rate, up to 96.5%, uses rear 6h still to have the antibacterial of excellence to prolong Continuous effect.
(4), one exempt from water sterilizing abluent, it is characterized in that: described middle carbon alcohol TiO2Decontamination skin-protection is exempted from water sterilization and is disappeared Poison abluent, is made into % by following proportion by weight
Preparation method: add water in the reactor of band stirring, be warming up to 60~70 DEG C, in stirring (under 30~50r/min Add alkyl alcohol ethoxylates sulfate, after dissolving about 0.5~1.5h, be cooled to 40~60 DEG C, be sequentially added into alkylol and gather Oxygen vinyl Ether, alkyl betaine, alkylbenzenesulfonate, ethanol, middle carbon alcohol and acetylated lanolin, it is completely dissolved, stands froth breaking After, encapsulation is finished product.
This product still has the strongest detergency when washing under low temperature and hard water conditions, for northern area and with well water, Spring water is that the occasion effect at water source becomes apparent from.
This product is diluted 1~3 times with 20%~90% ethanol water, non-water hand cleanser can be also served as and use.
This product formula is reasonable, and hard water resistance performance is good, and dirt-removing power is strong: PH is neutral, and comfortable feel has no side effect and stings Swash property, use safety.
Below in conjunction with examples of implementation, the present invention is further elucidated with:
Specific implementation method:
Embodiment 1, one exempt from water sterilizing abluent, it is characterized in that: described sodium alginate carbamide skin moistening anticracking exempts from water Sterilizing abluent, is made into % by following masses proportioning
Embodiment 2, (2), one exempt from water sterilizing abluent, it is characterized in that: the described anti-skin of Herb Gynostemmae Pentaphylli nanometer silver takes off Skin eczema of chapping exempts from water sterilizing abluent, is made into % by following mass parts
A phase
Herb Gynostemmae Pentaphylli extract 1.5-4.5;Tea saponin 2-6;
Polysorbate60 0.5-1.5;
B phase
Glycyrrhizic acid 1-3;Selenium-rich deodorize vegetable oil 2-6;
C phase
Polyvinyl alcohol 2-6;Polyethylene adjoins pyrrolidone 0.7-2.1;
D phase
Polyethylene Glycol 3-9;Octadecanol 1.5-4.5;
Compound glycerin 3-9;Spice 0.4-1.2;
Water adds to 100%.
Embodiment 3, one exempt from water sterilizing abluent, it is characterized in that: described Aloe tea tree oil ZnOw ZnOw Clean the anti-pruritus of clean skin and exempt from water sterilizing abluent, be made into % by following masses proportioning
Embodiment 4, one exempt from water sterilizing abluent, it is characterized in that: described middle carbon alcohol TiO2Decontamination skin-protection is exempted from water and is killed Bacterium sterilization abluent, is made into % by following proportion by weight

Claims (4)

1. exempt from a water sterilizing abluent, it is characterized in that: described sodium alginate carbamide skin moistening anticracking is exempted from water sterilizing and washed Clean dose, it is made into % by following masses proportioning
2. exempt from a water sterilizing abluent, it is characterized in that: the described anti-skin peeling of Herb Gynostemmae Pentaphylli nanometer silver eczema of chapping exempts from water Sterilizing abluent, is made into % by following mass parts
3. exempt from a water sterilizing abluent, it is characterized in that: described Aloe tea tree oil ZnOw ZnOw cleans clean skin to be prevented Pruritus exempts from water sterilizing abluent, is made into % by following masses proportioning
4. exempt from a water sterilizing abluent, it is characterized in that: described middle carbon alcohol TiO2Decontamination skin-protection is exempted from water sterilizing and is washed clean Agent, is made into % by following proportion by weight
CN201610719354.0A 2016-08-16 2016-08-16 Exempt from water sterilizing abluent Pending CN106166128A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249176A (en) * 2020-02-21 2020-06-09 华熙生物科技股份有限公司 No-clean disinfectant, preparation method and application thereof
CN112920914A (en) * 2021-02-22 2021-06-08 广州道明研究院有限公司 Fragrance-retaining bead with sterilization effect and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991512A (en) * 2009-08-17 2011-03-30 刘庆民 Anhydrous hand cleaning agent
CN102178623A (en) * 2010-12-24 2011-09-14 徐美仙 Natural water-free hand washing lotion
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CN102178623A (en) * 2010-12-24 2011-09-14 徐美仙 Natural water-free hand washing lotion
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CN112920914A (en) * 2021-02-22 2021-06-08 广州道明研究院有限公司 Fragrance-retaining bead with sterilization effect and preparation method thereof
CN112920914B (en) * 2021-02-22 2022-05-27 广州道明研究院有限公司 Fragrance-retaining bead with sterilization effect and preparation method thereof

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