CN105456054A - Water-free hand sanitizer and preparing method thereof - Google Patents
Water-free hand sanitizer and preparing method thereof Download PDFInfo
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- CN105456054A CN105456054A CN201610001327.XA CN201610001327A CN105456054A CN 105456054 A CN105456054 A CN 105456054A CN 201610001327 A CN201610001327 A CN 201610001327A CN 105456054 A CN105456054 A CN 105456054A
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- water
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- hand cleanser
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a water-free hand sanitizer. The water-free hand sanitizer is prepared from, by weight, 25-35% of deionized water, 0.2-0.3% of Carbomer, 62-73% of ethyl alcohol, 0.1-0.2% of triclosan, 1.0-2.0% of D-panthenol, 0.4-1% of glycerinum, 0.1-0.3% of triethanolamine and 0.2-0.5% of essence. According to the technical scheme, dual bacteriostasis and sterilization are achieved through ethyl alcohol and triclosan, and glycerinum, D-panthenol and triethanolamine are adopted to achieve moistening and other beautifying effects.
Description
Technical field
The present invention relates to handwashing liquid technical field, especially a kind of non-water hand cleanser.
The another one aspect that the present invention relates to is the preparation method of producing non-water hand cleanser.
Background technology
Wash one's hands as tradition the renewal product of apparatus fancy soap, handwashing liquid has sterilization, stimulates little, to avoid secondary pollution advantage to hand.Solids due to fancy soap is easy to be infected with dirt to hand and antibacterial, becomes secondary pollution source, and handwashing liquid and hands contact surface are generally just at the pump head of bottle, and pump head is easy to clean, can avoid the probability of cross infection preferably.Compared with fancy soap, alkali content is low, little to the stimulation of hand.Therefore the research and development of handwashing liquid are just becoming the focus of detergent industry.
Non-water washing handwashing liquid, do not need to rinse with water just to play the effect of washing one's hands, compared with general handwashing liquid, Non-water washing handwashing liquid does not limit by water source, uses more convenient in the wild.
Exempted from water hand cleanser and generally referred to anti-, bacteria resistance function, and saw curry shape and exempted from water wiping hands liquid.Its main component is carbomer and ethanol or antibacterial, because it is not traditional surfactant-based handwashing liquid, just have have anti-a, bacteria resistance function see curry, the industry standard that domestic present stage is also ununified.Domestic present stage there are two kinds of principal modes with regard to anti-, bacteria resistance function in this series products, and one is that adds a small amount of ethanol in addition exempted from water hand cleanser with professional antibacterial for sterilization main component; What another kind was traditional 70% ethanol as sterilization main component exempted from water hand cleanser.Although this two series products can reach function that is anti-, fungistatic effect, in use all existing defects, and there is no other similar functions of seeing curry shape cosmetics.Such as, with professional antibacterial be sterilization main component exempted from water hand cleanser due to ethanol very few, excess moisture, in use moisture evaporation is slow, and hands is not easy to do.And using traditional 70% ethanol as sterilization main component to exempt from water hand cleanser in use ethanol volatilization fast, but ethanol only just has the function of sterilization in the concentration of about 70%, therefore, this washing hands of exempting from is seen curry and is not in use had sterilizing function because alcohol concentration declines rapidly.Above two kinds of mass defects exempted from water hand cleanser and exist because of it, cause its practical effect not good.
For above-mentioned technical problem, China Patent No. is in the technological document of anhydrous hand cleaner liquid and preparation method thereof by name of ZL200610028459.8, once discloses a kind of such technology: this non-water hand cleanser comprises ethanol, carbomer, deionized water, aminomethyl propanol, propylene glycol, triclosan and glycerol.This technology, can play dual decontamination, bactericidal action.
But above-mentioned solution is only the function for disinfection, can not play the cosmetic industries such as beauty treatment, moisturizing.
Summary of the invention
The present invention, in order to overcome the deficiencies in the prior art, proposes a kind of non-water hand cleanser, on antibacterial, the antibacterial basis of improving non-water hand cleanser, and the cosmetic function such as have moist, moisturizing concurrently and enhance metabolism.
In order to solve above-mentioned technical problem, the basic technical scheme that the present invention proposes is: a kind of non-water hand cleanser, comprise deionized water, carbomer, ethanol, triclosan and glycerol, also comprise D-panthenol, triethanolamine and essence, wherein various component is as follows according to percentage by weight:
Further, calculate according to percentage by weight, the proportioning of each component is as follows:
Further, described essence is Fructus Citri Limoniae essence.
Another aspect of the present invention proposes a kind of preparation method of producing non-water hand cleanser, and it comprises the steps:
(1), at room temperature, deionized water is added in batch mixing a mixing bowl, starts stirring,
(2), by carbomer slowly join in batch mixing a mixing bowl, stirring and dissolving is even;
(3), in another container add ethanol, under agitation add triclosan and D-panthenol successively, join after being stirred to dissolving completely in the batch mixing a mixing bowl in step (2), continue to stir;
(4) in the batch mixing a mixing bowl in step (3), slowly add glycerol continue to be stirred to mixing fully;
(5), in the batch mixing a mixing bowl in step (4), triethanolamine adjust ph is slowly added between 5.5-7.0;
(6), in the batch mixing a mixing bowl in step (5) slowly add essence, continue stirring and stop after 30 minutes stirring;
(7), fill after 24 hours is left standstill.
Carbomer is the high molecular polymer of acrylic acid bonding allyl sucrose or tetramethylolmethane allyl ether.Calculate by dry product, should be 56.0% ~ 68.0% containing carboxylic acid group (-COOH); For white loose sprills; There is characteristic micro-smelly; Have draw moist; Be a kind of extraordinary gelled matrix, glittering and translucent texture China Resources, is used as thickening agent, stabilising emulsifier in the product.
Ethanol, the concentration of this ethanol is 70% in the present invention, has the effect of sterilizing.
Triclosan, chemical molecular formula is C12H7C13O2, has another name called " triclosan ", " Triclosan " etc., and triclosan normality is white or canescence crystalline powder, slightly phenol stink.Water insoluble, be soluble in alkali liquor and organic solvent.Triclosan is a kind of broad spectrum antimicrobicide, is widely used among the household chemicals such as soap, toothpaste.In the present invention, mainly function that is antibacterial, that sterilize together is realized with ethanol.Addition is 0.1 ~ 0.2% anti-, the bacteria resistance function that can reach extraordinary handwashing liquid (GB19877.1-2005) standard regulation.
Triethanolamine, adds triethanolamine in liquid detergent, can improve oily dirt, particularly the removal of nonpolar sebum, meanwhile, can improve detergency ability by improving alkalescence; And there is its fabulous compatibility.In the present invention, during this triethanolamine is used for and carbomer, system is become and sees curry shape liquid.
Glycerol, is glycerol, can dissolve with water with any ratio, and low concentration glycerin solution can do lubricating oil and moisten skin.
D-panthenol, the nursing role on skin shows as the wetting agent of deep infiltration, stimulates epithelial growth, promotes wound healing, plays antiinflammation; Nursing role on hair shows as lasting moisture-keeping functions.
In technical scheme of the present invention, achieve dual bacteriostatic, sterilizing function by ethanol and triclosan; And employ glycerol, D-panthenol, triethanolamine reach the cosmetic result such as moistening, moisturizing.
Detailed description of the invention
A kind of non-water hand cleanser of the present invention, wherein various component is as follows according to percentage by weight: deionized water 25-35%; Carbomer 0.2-0.3%; Ethanol 62-73%; Triclosan 0.1-0.2%; D-panthenol 1.0-2.0%; Glycerol 0.4-1%; Triethanolamine 0.1-0.3%; And essence 0.2-0.5%.
Concrete, in one embodiment of the invention, its concrete content is as follows, take 100g as gross mass, wherein deionized water 32g; Carbomer 0.25g; Ethanol 65g; Triclosan 0.15g; D-panthenol 1.5g; Glycerol 0.7g; Triethanolamine 0.2g; And Fructus Citri Limoniae essence 0.2g.
Specifically, the model that adopts of each middle component is as follows:
The obtained method of above-mentioned non-water hand cleanser is as follows:
(1), at room temperature, deionized water 32g is added in batch mixing a mixing bowl, starts stirring,
(2), by 0.25g carbomer slowly join in batch mixing a mixing bowl, stirring and dissolving is even;
(3), in another container add ethanol 65g, under agitation add 0.15g triclosan, 1.5gD-pantothenylol successively, join after being stirred to dissolving completely in the batch mixing a mixing bowl in step (2), continue to stir;
(4), in the batch mixing a mixing bowl in step (3), slowly add 0.7g glycerol to continue to be stirred to abundant mixing;
(5), in the batch mixing a mixing bowl in step (4), 0.2g triethanolamine adjust ph is slowly added between 5.5-7.0;
(6), in the batch mixing a mixing bowl in step (5), slowly adding Fructus Citri Limoniae essence 0.2g, continuing stirring and stop after 30 minutes stirring.
The non-water hand cleanser be worth by said method, it detects data as shown in Table 1:
Table one
Microbiological indicator and and detection method in table 2
Table 2
Raw material carbomer used in formula system of the present invention should adopt high-grade, the high grade of transparency, Clear & Transparent to ensure exempting from water hand cleanser product appearance, thus better ensure that product quality.Produce exempted from water hand cleanser owing to have employed this formula system, it is anti-, bacteriostasis strong and stable, and have more part cosmetic industry, product system is stablized, Clear & Transparent.The using function of its inherence and presentation quality all comparatively on market like product greatly improve.
The announcement of book and instruction according to the above description, those skilled in the art in the invention can also change above-mentioned embodiment and revise.Therefore, the present invention is not limited to detailed description of the invention disclosed and described above, also should fall in the protection domain of claim of the present invention modifications and changes more of the present invention.In addition, although employ some specific terms in this description, these terms just for convenience of description, do not form any restriction to the present invention.
Claims (4)
1. a non-water hand cleanser, comprises deionized water, carbomer, ethanol, triclosan and glycerol, it is characterized in that, also comprises D-panthenol, triethanolamine and essence, and wherein various component is as follows according to percentage by weight:
2. non-water hand cleanser as claimed in claim 1, is characterized in that: calculate according to percentage by weight, the proportioning of each component is as follows:
3. non-water hand cleanser as claimed in claim 1 or 2, is characterized in that: described essence is Fructus Citri Limoniae essence.
4. for the manufacture of a preparation method for the non-water hand cleanser of one of claims 1 to 3, it is characterized in that, comprise the steps:
(1), at room temperature, deionized water is added in batch mixing a mixing bowl, starts stirring,
(2), by carbomer slowly join in batch mixing a mixing bowl, stirring and dissolving is even;
(3), in another container add ethanol, under agitation add triclosan and D-panthenol successively, join after being stirred to dissolving completely in the batch mixing a mixing bowl in step (2), continue to stir;
(4) in the batch mixing a mixing bowl in step (3), slowly add glycerol continue to be stirred to mixing fully;
(5), in the batch mixing a mixing bowl in step (4), triethanolamine adjust ph is slowly added between 5.5-7.0;
(6), in the batch mixing a mixing bowl in step (5) slowly add essence, continue stirring and stop after 30 minutes stirring;
(7), fill after 24 hours is left standstill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610001327.XA CN105456054A (en) | 2016-01-04 | 2016-01-04 | Water-free hand sanitizer and preparing method thereof |
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| CN201610001327.XA CN105456054A (en) | 2016-01-04 | 2016-01-04 | Water-free hand sanitizer and preparing method thereof |
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| CN201610001327.XA Pending CN105456054A (en) | 2016-01-04 | 2016-01-04 | Water-free hand sanitizer and preparing method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106166128A (en) * | 2016-08-16 | 2016-11-30 | 南通蛇类治疗研究所 | Exempt from water sterilizing abluent |
| CN106474006A (en) * | 2016-09-22 | 2017-03-08 | 长兴净安环保科技有限公司 | A kind of water-free hand sanitizer and preparation method thereof |
| CN106474013A (en) * | 2016-12-12 | 2017-03-08 | 上海商玺伟康（商丘）医药用品有限公司 | A kind of have skin care effect exempt from hand-wash disinfectant solution and preparation method thereof |
| CN108721129A (en) * | 2018-08-24 | 2018-11-02 | 上海理工大学 | A kind of antibacterial moisturizing Non-water washing hand cleanser and preparation method thereof |
| CN110448487A (en) * | 2019-08-26 | 2019-11-15 | 上海应用技术大学 | A kind of disposable bacteriostatic hand sanitizer and preparation method containing fingered citron essential oil microemulsion |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480221A (en) * | 2003-07-09 | 2004-03-10 | 中国医学科学院生物医学工程研究所 | Washing free gel for disinfection |
| US20080139656A1 (en) * | 2004-12-09 | 2008-06-12 | The Dial Corporation | Compositions Having a High Antiviral and Antibacterial Efficacy |
| CN101658469A (en) * | 2009-09-10 | 2010-03-03 | 上海泛亚生命科技有限公司 | Cleaning-free hand sanitizer and preparation thereof |
-
2016
- 2016-01-04 CN CN201610001327.XA patent/CN105456054A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480221A (en) * | 2003-07-09 | 2004-03-10 | 中国医学科学院生物医学工程研究所 | Washing free gel for disinfection |
| US20080139656A1 (en) * | 2004-12-09 | 2008-06-12 | The Dial Corporation | Compositions Having a High Antiviral and Antibacterial Efficacy |
| CN101658469A (en) * | 2009-09-10 | 2010-03-03 | 上海泛亚生命科技有限公司 | Cleaning-free hand sanitizer and preparation thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106166128A (en) * | 2016-08-16 | 2016-11-30 | 南通蛇类治疗研究所 | Exempt from water sterilizing abluent |
| CN106474006A (en) * | 2016-09-22 | 2017-03-08 | 长兴净安环保科技有限公司 | A kind of water-free hand sanitizer and preparation method thereof |
| CN106474013A (en) * | 2016-12-12 | 2017-03-08 | 上海商玺伟康（商丘）医药用品有限公司 | A kind of have skin care effect exempt from hand-wash disinfectant solution and preparation method thereof |
| CN108721129A (en) * | 2018-08-24 | 2018-11-02 | 上海理工大学 | A kind of antibacterial moisturizing Non-water washing hand cleanser and preparation method thereof |
| CN110448487A (en) * | 2019-08-26 | 2019-11-15 | 上海应用技术大学 | A kind of disposable bacteriostatic hand sanitizer and preparation method containing fingered citron essential oil microemulsion |
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Application publication date: 20160406 |
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