CN106138760A - A kind of Chinese medicine preparation treating coronary heart disease - Google Patents
A kind of Chinese medicine preparation treating coronary heart disease Download PDFInfo
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Abstract
The invention belongs to the field of Chinese medicines, it is specifically related to a kind of Chinese medicine preparation treating coronary heart disease, it is characterized in that in parts by weight, formulated by following Chinese medicine material: Bai Long wears coloured silk 15～20 parts, latifolious rush rhizome 10～15 parts, 5～8 parts of pocket orchid, hangs Huang 5～8 parts, turtle shell 15～20 parts, Dendrobium densiflorum lindl 5～8 parts, the hook stem of noble dendrobium 5～8 parts, musk orchid 3～5 parts, ginseng 2～3 parts, keel 3～5 parts, the red root of herbaceous peony 5～8 parts, pearl powder 3～5 parts, polygala root 3～5 parts.It is an advantage of the current invention that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and there is nourishing YIN and clearing away fire, nourish heart the effect with network, CF can be improved, strengthen cardiac muscle oxygen content, make the increase in demand to blood for the cardiac muscle, reaching to dredge the activity of coronary blood tube wall, making the effects such as the elastic increase of coronary artery, treatment coronary heart disease has the features such as determined curative effect, instant effect, cure rate is high, have no side effect.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation treating coronary heart disease.
Background technology
Coronary heart disease (coronary heart disease) is common disease and the frequently-occurring disease of a kind of serious harm human health,
With raising and the aging population of people's living standard, the incidence of disease of this disease and case fatality rate occupy first place in angiocardiopathy
And ascendant trend is obvious year by year, become " first killer " of harm human health.In the nearest report of the World Health Organization (WHO)
Pointing out, the death rate of 2000-2020 myocardial infarction will be risen to the 1st by the 5th." national medium-term and long-term Science and Technology is sent out
Exhibition planning outline (2006～2020) " and " scientific tcm research and development outline " preventing and treating of cardiovascular major disease is classified as heavily
Point research field.
The Etiological of coronary heart disease is atherosclerotic (atherosclerosis, AS), and the cardiac muscle thus causing
Ischemic, downright bad pathological change.Its pathology pathogenesis makes blood fat raise mainly due to disorders of lipid metabolism, blood vessel fat
Matter deposition, soaking molten, blood vessel endothelium foam wanshing, the reaction of vascular wall chronic inflammatory makes coronary artery function of vascular endothelium and form
Damage, forms blood vessel endothelium atheromatous plaque, occurs that plaque rupture, thrombosis, hemadostewnosis or obturation make coronary blood further
Liquid dyshaemia, myocardial ischemia, myocardial cell damage, cause cardiac insufficiency.Coronary heart disease is broadly divided into clinically: (1) hides
Type；(2) angina pectoris；(3) myocardial infarction；(4) heart failure type；(5) sudden death type.
The prevention of coronary heart disease or treatment are based on the change and Lipid modulating of dietary life habits, coordinate antiplatelet
The drug therapy such as medicine, nitrate esters and beta-blocker, to mitigate the symptom of patient, are improved the quality of living, and improving prognosis is
Target.
Motherland's medical science thinks that coronary heart disease belongs to the category of " chest impediment and cardialgia ", the generation of this disease many turbid by healthy tendency virtual loss or phlegm,
Hemostasis, the stagnation of the circulation of vital energy, cold solidifying and cause heart vessel blockage stasis not smooth.Traditional Chinese medicine is basic rules for the treatment of treatment coronary diseases with " promoting blood circulation and removing blood stasis " for many years
Disease, achieves noticeable achievement.Such as Fufang Danshen Pian, Danshen Root dropping ball, storax pill for treating coronary heart disease etc..In recent years clinically for patients with coronary heart disease blood
The pathological change such as pipe, myocardial inflammation reaction, peroxidating stress damage, necrosis, is respectively adopted " reducing phlegm ", " removing toxic substances ", " fall
Turbid " etc. therapy, by experimental study confirm plurality of Chinese by regulating lipid metabolism, protection vascular endothelial cell, suppression lipid
The approach different from the balance between apoptosis, anti-inflammatory response etc. and ring are bred in peroxidating, suppression vascular smooth muscle cell proliferation, regulation
Joint, intervenes and treatment coronary heart disease.Such as Diaoxinxue Kang, Snakegourd Fruit tuber of pinellia Longstamen Onion Bulb soup, huanglian jiedu decoction, Turmeric P.E, Puerarin
Extract, red colouring agent for food, also used as a Chinese medicine etc..
Chinese patent drug is boundless comparatively speaking in the treatment market of coronary heart disease as can be seen here, it would be highly desirable to a kind of determined curative effect of exploitation
And the Chinese medicine of the treatment coronary heart disease notable, sophisticated technologies, drug quality are stable.
Content of the invention
According to above the deficiencies in the prior art, the present invention provides a kind of Chinese medicine preparation treating coronary heart disease, is particularly well-suited to
Suffer from the gerontal patient of coronary heart disease, the especially gerontal patient of heart kidney yin deficiency type, its secondary work evident in efficacy, safe and reliable, nontoxic
With having wide potential applicability in clinical practice.
Applicant sums up discovery in a large amount of clinics, and the gerontal patient suffering from coronary heart disease often has the table of kidney qi loss
Existing, this is because with advancing age, patient's visceral-qi function is gradually moved back, and deficiency of the kidney causes the Yang-function insufficiency of kidneyzang, it is impossible to warm each internal organs, causes
Sun declines the stagnation of the circulation of vital energy, hematogenous blockage, and qi deficiency to blood stasis occurs；Or kidney yin is short, it is impossible to nourish the moon of internal organs, it is possible to cause yin deficiency and blood stasis.
Wherein short most commonly seen with kidney yin, patient shows as pained feeling oppressed, palpitation and night sweat, and dysphoria is insomnia, soreness of waist and knee, dizzy ear
Ring, dry mouth and constipation, red tongue with a little fluid, tongue is thin or shells, and thready rapid pulse or rush generation, applicant is defined as heart kidney yin deficiency type through differentiation of symptoms and signs for classification of syndrome.
For heart kidney yin deficiency type this class patient, applicant proposes techniques below scheme:
A kind of Chinese medicine preparation treating coronary heart disease of the present invention, in parts by weight, is joined by following Chinese medicine material
System forms: Bai Long wear color 15～20 parts, latifolious rush rhizome 10～15 parts, 5～8 parts of pocket orchid, hang yellow 5～8 parts, turtle shell 15～20 parts,
Dendrobium densiflorum lindl 5～8 parts, the hook stem of noble dendrobium 5～8 parts, musk orchid 3～5 parts, ginseng 2～3 parts, keel 3～5 parts, the red root of herbaceous peony 5～8 parts, treasure
3～5 parts of pearl powder, polygala root 3～5 parts.
Wherein, preferred version is as follows:
In parts by weight, formulated by following Chinese medicine material: Bai Long wears coloured silk 15 parts, latifolious rush rhizome 10 parts, pocket orchid 5
Part, hang yellow 5 parts, turtle shell 15 parts, Dendrobium densiflorum lindl 5 parts, the hook stem of noble dendrobium 5 parts, musk orchid 3 parts, ginseng 2 parts, keel 3 parts, the red root of herbaceous peony 5
Part, pearl powder 3 parts, polygala root 3 parts.
Also can be formulated by following Chinese medicine material in parts by weight: Bai Long wear color 20 parts, latifolious rush rhizome 15 parts,
Blue 8 parts of pocket, hang yellow 8 parts, turtle shell 20 parts, Dendrobium densiflorum lindl 8 parts, the hook stem of noble dendrobium 8 parts, musk orchid 5 parts, ginseng 3 parts, keel 5 parts, red in vain
Chinese herbaceous peony 8 parts, pearl powder 5 parts, polygala root 5 parts.
Also can be formulated by following Chinese medicine material in parts by weight: Bai Long wear color 18 parts, latifolious rush rhizome 12 parts,
Blue 6 parts of pocket, hang yellow 6 parts, turtle shell 18 parts, Dendrobium densiflorum lindl 7 parts, the hook stem of noble dendrobium 7 parts, musk orchid 4 parts, ginseng 3 parts, keel 4 parts, red in vain
Chinese herbaceous peony 6 parts, pearl powder 4 parts, polygala root 4 parts.
The preparation method of the Chinese medicine preparation for the treatment of coronary heart disease of the present invention, prepares: in accordance with the following methods according to formula
Weigh Chinese medicine material and join in container, add water cover powder soak 10～20 minutes, add water not powder 3～5 centimetres,
Decoct with high heat and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then add water not powder 3～5 centimetres, use
Intense fire decocts uses slow fire boiling instead 15～20 minutes again to boiling, and then removing slag takes filtrate, and filtrate merges twice.
During use, 200～300ml every time, sooner or later respectively once.
Pharmacology analysis:
Bai Long wears coloured silk: hardship pungent, micro-, flat.Regulating menstruation and activating blood, clearing away heat and promoting diuresis.For postpartum abdominal pain, irregular menstruation, acute nephritis,
Uterine hemorrhage, mastitis, erysipelas, furuncle.
Latifolious rush rhizome: pungent, bitter is flat.Regulating qi-flowing for relieving pain, regulating menstruation and activating blood.Cure mainly stagnation of QI due to depression of the liver, pain in chest and hypochondrium, menstrual disorder, metrorrhagia
Carry inferior disease.
Pocket is blue: acid sweet, puckery, micro-, flat.Regulating menstruation and activating blood, anti-inflammatory analgetic.Cure mainly irregular menstruation, dysmenorrhoea, amenorrhoea, adnexitis, wing
Guang is scorching, hernia etc..
Hang Huang: Gan Xin, flat.Dispelling rheumatism, qi-restoratives is subsided a swelling, and regulating menstruation and activating blood cures cold, rheumatalgia pain, tuberculosis, oedema,
Puerperal asthenia, irregular menstruation, traumatic injury.
Turtle shell: salty, is slightly cold.Return liver, kidney channel.Nourishing and suppressing Yang, softening and resolving hard mass, bring down a fever except steaming.For fever due to yin deficiency, the hot bone of labor
Steaming, endogenous deficient wind, through closing, lump in the abdomen, chronic malaria malaria is female.
Dendrobium densiflorum lindl: sweet, light, micro-salty, cold.Nourishing YIN for benefiting the kidney, promotes the production of body fluid to quench thirst.Spider pyreticosis, hinders Tianjin, dry polydipsia, after being ill void
Weak.
The hook stem of noble dendrobium: sweet, is slightly cold.Reinforcing stomach reg fluid, nourishing Yin and clearing heat.Hindering body fluid deficiency, dry polydipsia for the moon, food is few retches, after being ill
Abnormal heat, mesh is secretly failed to understand.
Musk orchid: sweet, temperature.Enriching yin and nourishing kidney, nourishing the stomach, menstruation regulating.For neurasthenia, dizzy insomnia, irritated thirsty appetite is not
Shake, poliosis, irregular menstruation.
Ginseng: hardship sweet, micro-is flat.Return spleen, lung, the heart channel of Hang-Shaoyin.Reinforcing vital energy, multiple arteries and veins takes off admittedly, reinforces the spleen to benefit the lung, promotes the production of body fluid, calms the nerves.With
Yu Tixu is intended to take off, the cold weak pulse of limb, and insufficiency of the spleen food is few, and the deficiency syndrome of the lung is breathed with cough, and Tianjin wound is thirsty, and interior heat is quenched one's thirst, and prolonged illness void is thin, palpitation with fear insomnia, sun
Impotence palace is cold；Heart failure, cardiogenic shock.
Keel: sweet, puckery are flat.Calmness, the puckery essence of arrest sweating, myogenic sore.For neurasthenia, palpitaition, have a sleepless night, dreaminess, from
Sweat, night sweat, seminal emission, the enuresis, uterine bleeding, under band；External application control sore for a long time burst do not hold back.
The red root of herbaceous peony: smell is bitter flat, nontoxic.Curing mainly perverse trend stomachache, removing blood-arthralgia, broken heavily fortified point is long-pending, fever and chills, sick tired, and pain relieving, profit is little
Just, benefit gas.
Pearl powder: sweet, salty, cold.The thoughts of returning home, Liver Channel.Calming the nerves arresting convulsion, improving eyesight disappears screen, solves taking poison and growing muscle due.For insomnia of palpitating with fear, frightened
Wind epilepsy, the raw cloudiness of mesh, sore is not held back.
Polygala root: bitter, pungent, warm.The thoughts of returning home, kidney, lung channel.Calm the nerves intelligence development, eliminate the phlegm, detumescence.The insomnia causing for breakdown of the normal physiological coordination between the heart and the kidney
Dreaminess, forgetful palpitation with fear, wandering, expectoration is not well, sore swollen toxin, mastosis.
In medicament composing prescription of the present invention, Bai Long wears coloured silk, latifolious rush rhizome, pocket is blue, hang yellow nourishing painstaking effort and logical heart arteries and veins；Turtle shell, thick
Yellow grass, the hook stem of noble dendrobium, musk orchid grow water yin-nourishing, to drop the fire of deficiency type；Ginseng, keel, red root of herbaceous peony benefit help the motive；Pearl powder, polygala root traffic
Heart kidney, mental-tranquilization.
It is an advantage of the current invention that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.
All medicine phases and have nourishing YIN and clearing away fire, nourish heart and effect of network, can improve CF, strengthen cardiac muscle oxygen content, make cardiac muscle
Increase in demand to blood, reaches to dredge the activity of coronary blood tube wall, makes the effects such as the elastic increase of coronary artery, treatment hat
Worry has the features such as determined curative effect, instant effect, cure rate is high, have no side effect.
Outcome measure:
1st, case selection:
As the medicine for the treatment of coronary heart disease, select patients with coronary heart disease 100 case to carry out clinical observation, and patient belongs to heart kidney
The gerontal patient of YIN-deficiency type, wherein male 52 cases, women 48 case, age 62-85 year, average age 71 years old, course of disease 1-10, averagely
2.8 year.
2nd, medicine for treatment:
Treatment group patient takes medicine of the present invention, every time 200～300ml, and sooner or later each 7 days is once a course for the treatment of, according to
The state of an illness takes 5-10 the course for the treatment of continuously, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3rd, Outcome measure:
Effective: the cardiac distresses such as physique strengthens, feeling of oppression and pain in the chest are relieved, and electrocardiogram shows that myocardial blood supply is obviously improved；
Effective: the cardiac distresses such as physique strengthens, feeling of oppression and pain in the chest have been alleviated；
Invalid: all diseases are unchanged.
4th, treatment results:
Effective 55 cases, effective 39 cases, invalid 6 cases, total effective rate is 94%.
It is exemplified below a model case:
Wang, man, 72 years old, patient's private prosecution before being admitted to hospital 4+ begin without obvious cause occur uncomfortable in chest breathe hard and dizziness, when companion
Had palpitation, can aggravate when tired, can alleviate through having a rest, and blood discovery high blood pressure is surveyed in our hospital's outpatient service of once repeatedly seeing a doctor, and reaches as high as
210/110mmHg, looks into electrocardiogram prompting " deficiency myocardial blood supply ", is diagnosed as " coronary heart disease, essential hypertension ", gives step-down, expands
The Western medicine oral medications such as blood vessel, symptom all can be alleviated, but be easy to repeatedly.Within nearly 5 days, increase the weight of earlier above without obvious cause sense symptom, chest
Secret anguish, when as when stop, with palpitation, deafness and tinnitus, dry mouth and constipation, especially with after activity substantially, do not give treatment outside institute, today
Again seeing a doctor our hospital's outpatient service, outpatient service is intended " coronary heart disease, essential hypertension " and is hospitalized and be admitted to hospital.Under occasion: sensation of oppression and faint pain in the chest, when as when stop,
Palpitation, soreness of waist and knee, red tongue with a little fluid, tongue is thin, thready rapid pulse.Take Chinese medicine preparation of the present invention subsequently, after taking 5 courses for the treatment of,
The cardiac distresses such as feeling of oppression and pain in the chest are relieved, and electrocardiogram shows that myocardial blood supply is obviously improved, after continuing to take 5 courses for the treatment of, and medication
Number of times halves and adheres to long-term taking, does not occurs obvious illness so far.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine preparation treating coronary heart disease, in parts by weight, formulated by following Chinese medicine material: Bai Long wears
Color 15 parts, latifolious rush rhizome 10 parts, blue 5 parts of pocket, hang yellow 5 parts, turtle shell 15 parts, Dendrobium densiflorum lindl 5 parts, the hook stem of noble dendrobium 5 parts, musk orchid 3 parts, people
Join 2 parts, keel 3 parts, the red root of herbaceous peony 5 parts, pearl powder 3 parts, polygala root 3 parts.
Embodiment 2:
A kind of Chinese medicine preparation treating coronary heart disease, in parts by weight, formulated by following Chinese medicine material: Bai Long wears
Color 20 parts, latifolious rush rhizome 15 parts, blue 8 parts of pocket, hang yellow 8 parts, turtle shell 20 parts, Dendrobium densiflorum lindl 8 parts, the hook stem of noble dendrobium 8 parts, musk orchid 5 parts, people
Join 3 parts, keel 5 parts, the red root of herbaceous peony 8 parts, pearl powder 5 parts, polygala root 5 parts.
Embodiment 3:
A kind of Chinese medicine preparation treating coronary heart disease, in parts by weight, formulated by following Chinese medicine material: Bai Long wears
Color 18 parts, latifolious rush rhizome 12 parts, blue 6 parts of pocket, hang yellow 6 parts, turtle shell 18 parts, Dendrobium densiflorum lindl 7 parts, the hook stem of noble dendrobium 7 parts, musk orchid 4 parts, people
Join 3 parts, keel 4 parts, the red root of herbaceous peony 6 parts, pearl powder 4 parts, polygala root 4 parts.
Embodiment 4:
Fill a prescription described in embodiment 1～3 and prepare the Chinese medicine preparation for the treatment of coronary heart disease in accordance with the following methods: in weighing according to formula
Medicine raw material simultaneously joins in container, add water cover powder soak 10～20 minutes, add water not powder 3～5 centimetres, with high heat
Decoct and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then add water not powder 3～5 centimetres, decoct with high heat
Boiling and using slow fire boiling again instead 15～20 minutes to boiling, then removing slag takes filtrate, and filtrate merges twice.
Claims (4)
1. the Chinese medicine preparation treating coronary heart disease, it is characterised in that in parts by weight, prepared by following Chinese medicine material and
Become: Bai Long wears coloured silk 15～20 parts, latifolious rush rhizome 10～15 parts, 5～8 parts of pocket orchid, hangs yellow 5～8 parts, turtle shell 15～20 parts, slightly Huang
Grass 5～8 parts, the hook stem of noble dendrobium 5～8 parts, musk orchid 3～5 parts, ginseng 2～3 parts, keel 3～5 parts, the red root of herbaceous peony 5～8 parts, pearl powder 3
～5 parts, polygala root 3～5 parts.
2. a kind of Chinese medicine preparation treating coronary heart disease according to claim 1, it is characterised in that in parts by weight, by
Following Chinese medicine material is formulated: Bai Long wears coloured silk 15 parts, latifolious rush rhizome 10 parts, blue 5 parts of pocket, hangs yellow 5 parts, turtle shell 15 parts, slightly Huang
Grass 5 parts, the hook stem of noble dendrobium 5 parts, musk orchid 3 parts, ginseng 2 parts, keel 3 parts, the red root of herbaceous peony 5 parts, pearl powder 3 parts, polygala root 3 parts.
3. a kind of Chinese medicine preparation treating coronary heart disease according to claim 1, it is characterised in that in parts by weight, by
Following Chinese medicine material is formulated: Bai Long wears coloured silk 20 parts, latifolious rush rhizome 15 parts, blue 8 parts of pocket, hangs yellow 8 parts, turtle shell 20 parts, slightly Huang
Grass 8 parts, the hook stem of noble dendrobium 8 parts, musk orchid 5 parts, ginseng 3 parts, keel 5 parts, the red root of herbaceous peony 8 parts, pearl powder 5 parts, polygala root 5 parts.
4. a kind of Chinese medicine preparation treating coronary heart disease according to claim 1, it is characterised in that in parts by weight, by
Following Chinese medicine material is formulated: Bai Long wears coloured silk 18 parts, latifolious rush rhizome 12 parts, blue 6 parts of pocket, hangs yellow 6 parts, turtle shell 18 parts, slightly Huang
Grass 7 parts, the hook stem of noble dendrobium 7 parts, musk orchid 4 parts, ginseng 3 parts, keel 4 parts, the red root of herbaceous peony 6 parts, pearl powder 4 parts, polygala root 4 parts.
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455804A (en) * | 2008-11-27 | 2009-06-17 | 朱新华 | Traditional Chinese medicine composition for treating coronary heart disease |
| CN103191252A (en) * | 2013-04-16 | 2013-07-10 | 张艳军 | Traditional Chinese medicine preparation for treating coronary disease and preparation method of traditional Chinese medicine preparation |
| CN103381258A (en) * | 2013-08-05 | 2013-11-06 | 李竞 | Depression-dispelling nerve-soothing granules and preparation method for oral solution of same |
| CN105288191A (en) * | 2015-11-18 | 2016-02-03 | 宿录贞 | Medicinal moxa stick for treating breast lumps |
| CN105381255A (en) * | 2015-12-12 | 2016-03-09 | 王光辉 | Formula for traditional Chinese medicine for treating heatstroke |
| CN105396071A (en) * | 2015-12-12 | 2016-03-16 | 王光辉 | Traditional Chinese medicine formula for treating children pneumonia |
| CN105582303A (en) * | 2016-03-22 | 2016-05-18 | 青岛市中心医院 | Traditional Chinese medicine preparation for treating coronary heart disease |
-
2016
- 2016-08-23 CN CN201610777782.9A patent/CN106138760A/en not_active Withdrawn
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455804A (en) * | 2008-11-27 | 2009-06-17 | 朱新华 | Traditional Chinese medicine composition for treating coronary heart disease |
| CN103191252A (en) * | 2013-04-16 | 2013-07-10 | 张艳军 | Traditional Chinese medicine preparation for treating coronary disease and preparation method of traditional Chinese medicine preparation |
| CN103381258A (en) * | 2013-08-05 | 2013-11-06 | 李竞 | Depression-dispelling nerve-soothing granules and preparation method for oral solution of same |
| CN105288191A (en) * | 2015-11-18 | 2016-02-03 | 宿录贞 | Medicinal moxa stick for treating breast lumps |
| CN105381255A (en) * | 2015-12-12 | 2016-03-09 | 王光辉 | Formula for traditional Chinese medicine for treating heatstroke |
| CN105396071A (en) * | 2015-12-12 | 2016-03-16 | 王光辉 | Traditional Chinese medicine formula for treating children pneumonia |
| CN105582303A (en) * | 2016-03-22 | 2016-05-18 | 青岛市中心医院 | Traditional Chinese medicine preparation for treating coronary heart disease |
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