CN105726932A - Traditional Chinese medicine preparation for treating coronary heart disease and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating coronary heart disease and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine preparation for treating coronary heart disease and a preparation method thereof. The traditional Chinese medicine preparation is prepared from following raw materials, by weight, 10-15 parts of red ginseng, 10-15 parts of codonopsis pilosula, 15-20 parts of panax notoginseng, 15-20 parts of salviae miltiorrhizae, 5-8 parts of radix bupleuri, 5-8 parts of rhizoma chuanxiong, 5-8 parts of poria cocos, 3-5 parts of radix ophiopogonis, 2-3 parts of fructus lycii, 3-5 parts of polygala tenuifolia, 5-10 parts of rhizoma alismatis, 1-2 parts of hawthorns, 1-2 parts of trogopterus dung and 2-3 parts of rhizoma anemarrhenae. The traditional Chinese medicines satisfy the specifications in Chinese pharmacopoeia, are safe and reliable, and are combined together to achieve the effects of improving coronary blood-flow volume and increasing cardiac muscle oxygen content, thereby increasing the demand of the cardiac muscle on blood, achieving the activity of dredging coronary artery blood vessel walls and improving the elasticity of the coronary artery. The preparation for treating the coronary heart disease has definite cure effects, has quick effects and high curative rate, and is free of side effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation treating coronary heart disease and preparation method thereof.
Background technology
Coronary heart disease (coronaryheartdisease) is commonly encountered diseases and the frequently-occurring disease of a kind of serious harm human health, raising and aged tendency of population along with people's living standard, the sickness rate of primary disease and case fatality rate occupy first place in cardiovascular disease and ascendant trend is obvious year by year, becomes " first killer " of harm human health.Pointing out in the report that World Health Organization (WHO) (WHO) is nearest, the mortality rate of 2000-2020 myocardial infarction will be risen to the 1st by the 5th.The preventing and treating of cardiovascular major disease is classified as priority research areas by " National Program for Medium-to Long-term Scientific and Technological Development (2006～2020) " and " scientific tcm research and development outline ".
The Etiological of coronary heart disease is atherosclerosis (atherosclerosis, AS), and the myocardial ischemia thus caused, downright bad pathological change.Its pathology pathogenesis makes blood fat raise mainly due to lipid metabolic disorder, blood vessel lipidosis, soak molten, blood vessel endothelium foam wanshing, the reaction of blood vessel wall chronic inflammatory makes the damage of arteria coronaria vascular endothelial function and form, forms blood vessel endothelium atheromatous plaque, plaque rupture occurs further, thrombosis, angiostenosis or obturation make coronary blood circulation obstacle, myocardial ischemia, myocardial cell damage, causes cardiac insufficiency.Coronary heart disease is broadly divided into clinically: (1) concealment type；(2) angina pectoris；(3) myocardial infarction；(4) heart failure type；(5) sudden death type.
The prevention of coronary heart disease or treatment are based on the change and Lipid modulating of dietary life habits, coordinate the Drug therapys such as antiplatelet drug, nitrate esters and beta-blocker to alleviate the symptom of patient, improve the quality of living, and improving prognosis is target.
Motherland's medical science thinks that coronary heart disease belongs to the category of " obstruction of qi in the chest and cardialgia ", generation many, blood stasis, the stagnation of QI, the cold coagulation turbid by healthy energy virtual loss or expectorant of primary disease and cause blockage of the cardiac vessels not smooth.Chinese medicine treats coronary heart disease with " blood circulation promoting and blood stasis dispelling " for the basic rule for the treatment of for many years, achieves noticeable achievement.Such as FUFANG DANSHEN PIAN, Radix Salviae Miltiorrhizae drop pill, storax pill for treating coronary heart disease etc..In recent years clinically for the pathological change such as patients with coronary heart disease blood vessel, myocardial inflammation reaction, peroxidating stress damage, tissue necrosis; it is respectively adopted the method for the treatment of such as " reducing phlegm ", " removing toxic substances ", " the turbid descending "; research confirms that plurality of Chinese breeds the approach different from the balance between apoptosis, anti-inflammatory response etc. and link by regulating lipid metabolism, protection vascular endothelial cell, anti-lipid peroxidation, suppression vascular smooth muscle cell proliferation, adjustment by experiment, intervenes and treatment coronary heart disease.Such as DIAOXINXUE KANG, Fructus Trichosanthis Rhizoma Pinelliae Bulbus Allii Macrostemonis soup, Rhizoma Coptidis toxic materials clearing away decoction, Rhizoma Curcumae Longae extract, puerarin extract, Monas cuspurpureus Went etc..
Chinese patent medicine is boundless comparatively speaking in the treatment market of coronary heart disease as can be seen here, it would be highly desirable to develop a kind of determined curative effect and the Chinese medicine of the treatment coronary heart disease notable, sophisticated technologies, drug quality are stable.
Summary of the invention
According to above the deficiencies in the prior art, the present invention provides a kind of Chinese medicine preparation treating coronary heart disease and preparation method thereof, and it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
A kind of Chinese medicine preparation treating coronary heart disease of the present invention, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 10～15 parts, Radix Codonopsis 10～15 parts, Radix Notoginseng 15～20 parts, Radix Salviae Miltiorrhizae 15～20 parts, Radix Bupleuri 5～8 parts, Rhizoma Chuanxiong 5～8 parts, 5～8 parts of Poria, Radix Ophiopogonis 3～5 parts, Fructus Lycii 2～3 parts, Radix Polygalae 3～5 parts, Rhizoma Alismatis 5～10 parts, Fructus Crataegi 1～2 part, Oletum Trogopterori 1～2 part and the Rhizoma Anemarrhenae 2～3 parts.
Wherein, it is preferable that scheme is as follows:
According to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 10 parts, Radix Codonopsis 10 parts, Radix Notoginseng 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Bupleuri 5 parts, Rhizoma Chuanxiong 5 parts, 5 parts of Poria, Radix Ophiopogonis 3 parts, Fructus Lycii 2 parts, Radix Polygalae 3 parts, Rhizoma Alismatis 5 parts, Fructus Crataegi 1 part, Oletum Trogopterori 1 part and the Rhizoma Anemarrhenae 2 parts.
Can also according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 15 parts, Radix Codonopsis 15 parts, Radix Notoginseng 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Bupleuri 8 parts, Rhizoma Chuanxiong 8 parts, 8 parts of Poria, Radix Ophiopogonis 5 parts, Fructus Lycii 3 parts, Radix Polygalae 5 parts, Rhizoma Alismatis 10 parts, Fructus Crataegi 2 parts, Oletum Trogopterori 2 parts and the Rhizoma Anemarrhenae 3 parts.
The preparation method of the Chinese medicine preparation for the treatment of coronary heart disease of the present invention, prepare in accordance with the following methods: weigh raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10～20 minutes, add water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then adding water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 15～20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
During use, each 200～300ml, sooner or later respectively once.
Pharmacology analysis:
Radix Ginseng Rubra: be the cooked of Radix Ginseng, except the effect with invigorating primordial QI, spleen reinforcing lung, promoting the production of body fluid and inducing sedation of the mind, its property of medicine is warmer, has the advantages that fire is big, strength is sufficient, effect is strong, longer than strongly invigorating primordial QI, recuperating depleted YANG and rescuing the patient from collapse, nourishing qi to stop.From health body-building angle, Radix Ginseng Rubra is then insufficiency of vital energy and blood and the tonification good merchantable brand of inclined yang deficiency person, all appearance are often afraid of cold, trick is warm, dizziness asthenia, limbs fatigue, fatiguability, dyspnea with shortness of breath, time the performance such as sense coldness in the stomach, long-term diarrhea, insomnia and dreamful sleep, sexual impotence frequent micturition, all can be selected for Radix Ginseng Rubra and nourish.Cardiac muscle and blood vessel are had direct effect by Radix Ginseng Rubra, are typically in during low dose excited, suppress time heavy dose of.10% Radix Ginseng Rubra immersion 1 milliliter/kilogram gives cat (or rabbit) gavage, and amyocardia is had some improvement.Considerable degree of recovery is had during rewarming.Also there is the effect of antianaphylaxis shock and heart tonifying.Rat myocardial cell film ATPase activity is had inhibitory action by Radix Ginseng Rubra.
Radix Codonopsis: property is put down, sweet in the mouth, there is effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, anticancer, blood pressure lowering, anti-hypoxia, defying age, body immunity can also be strengthened, improve the activity of superoxide dismutase, strengthen the ability eliminating free radical, there is the effect of Gastrointestinal motility adjustment, antiulcer, gastric acid secretion inhibiting, reduction pepsin activity.Have a delicate constitution, insufficiency of vital energy and blood, shallow complexion, and puerperal asthenia person should eat after being ill；Deficiency of spleen-QI and stomach-QI, tired, limbs fatigue, anorexia and loose stool, chronic diarrhea, insufficiency of lung-QI, tachypnea of coughing, deficiency of vital energy and physically weak, it is easy to flu；Qi and blood deficiency person should eat；Chronic nephritis proteinuria person should eat；Chronic anaemia, chlorosis, leukemia, thrombocytopenic purpura and rickets patient should eat.
Radix Notoginseng: sweet micro-hardship, temperature, nontoxic.Enter liver, stomach, double enter the heart, large intestine.Hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, fall and flutter blood stasis, traumatic hemorrhage, carbuncle pain.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.Root is used as medicine, and containing TANSHINONES, for robustness emmenagogue, has blood stasis dispelling, tissue regeneration promoting, invigorates blood circulation, the effectiveness such as regulating menstruation, for gynecological's key medicine, cures mainly metrorrhagia, menoxenia, blood stasis, stomachache, dysmenorrhoea, amenorrhea, mausoleum pain.Treatment coronary heart disease there is good result.In addition also controlling the weak insomnia of nerve, arthralgia, anemia, mastitis, lymphadenitis, arthritis, furuncle pain is swollen, erysipelas, acute, chronic hepatitis, nephropyelitis, traumatic injury, and advanced schistosomiasis hepatosplenomegaly is insane.
Radix Bupleuri: bitter in the mouth is flat.Enter foot-shaoyang gallbladder, liver meridian, hands sun three Jiao less, hands faints cloudy percardium.Reconciling superficies and interior, soothing the liver, yang invigorating.Controlling alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower profit proctoptosis, menoxenia, uterine prolapse.
Rhizoma Chuanxiong: warm in nature, returns liver, gallbladder, heart channel, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, and the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go scattered, up up to top, mountain peak；Enter again blood system, descending up to the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis；Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, the function such as its residence of dangerous speech is pungent to be dissipated, resolving depression, sensible, pain relieving.
Poria: sweet, light is flat.GUIXIN, spleen, kidney channel.It is used as medicine and there is the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Radix Ophiopogonis: sweet, micro-hardship, it is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Fructus Lycii: sweet is flat.Return liver, kidney channel.Nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Radix Polygalae: bitter, pungent, warm.Return through GUIXIN, kidney, lung meridian.: nourish heart blood, relieving convulsion, mind calming, dissipates sputum.Treating five types of epilepsy opisthotonus, frightened jerk, mouth is spat saliva, and brothers' war is shaken, syncope, and urine reducing controls reddish and whitish turbid urine, stranguria marked by chyluria, and spermatorrhea be can't help.
Rhizoma Alismatis: sweet, cold.Enter bladder, kidney, three burnt, small intestinal four warps.Tonifying deficiency five kinds of over strain, except the five internal organs feeling of fullness, plays cloudy gas, and stopping leak is smart, quench one's thirst, drench drop, cuts off the water by bladder, three Jiao.Rhizoma Alismatis extractum is injected to dog and rabbit vein, has slight hypotensive effect, and continues about about 30 minutes.Various laboratory animals are had slight hypotensive effect by the Rhizoma Alismatis alcohol that rubs, and its hypotensive effect also not appreciably affects plasma renin and ACE activity or aldosterone level.The rabbit isolated aorta condition that epinephrine is caused by alisol extract in vitro is shunk relexation slowly.The Rhizoma Alismatis alcohol that rubs can suppress the contraction of the Rabbit thoracic aorta caused by angiotensin, and its contraction has dose dependent.Rhizoma Alismatis alcohol Perfused isolated heart technology of rubbing reduces cardiac output and heart rate and left ventricular pressure as seen, but can increase coronary flow.
Fructus Crataegi: sour in the mouth, cold, nontoxic.Enter spleen, stomach, Liver Channel.Help digestion long-pending, dissipating blood stasis blood, expelling tenia.Controlling meat to amass, lump in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia after-pains in puerperal, lochiorrhea, children's's breast food is stagnated.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.
Oletum Trogopterori: sweet in flavor and warm in property, nontoxic, enter Liver Channel, promoting blood circulation to remove blood stasis, parch to black stops blooding.Having a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, curing postpartum bleeding is suffered from abdominal pain；Parch to black controls metrostaxis；Traumatic injury, Serpentis, insect bite wound are controlled in external.Oletum Trogopterori 20mg/kg femoral artery injects and makes anesthesia Canine femoral artery blood flow increase, and vascular resistance reduces.Oletum Trogopterori Aqueous extracts 200ug/ml can significantly reduce the oxygen consumption of rat neonatal rat Cardiac Cells In Vitro.
The Rhizoma Anemarrhenae: bitter in the mouth, cold.Enter lung, stomach, kidney channel.Nourishing YIN to lower pathogenic fire, moisturizes laxation.Control dysphoria with smothery sensation to quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.
It is an advantage of the current invention that the Chinese medicine used meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and coronary flow can be improved, strengthen cardiac muscle oxygen content, make the cardiac muscle increase in demand to blood, reach the activity of dredging coronary blood tube wall, make the effects such as coronary artery elasticity increase, the features such as treatment coronary heart disease has determined curative effect, instant effect, cure rate is high, have no side effect.
Outcome measure:
1, case selection:
As treatment coronary heart disease medicine, select patients with coronary heart disease 100 example carry out clinical observation, wherein male 52 examples, women 48 example, age 45-85 year, 55 years old mean age, course of disease 1-10, average 2.8 years.
2, medicine for treatment:
Treatment group patient takes medicine of the present invention, each 200～300ml, sooner or later each once within 7 days, be a course for the treatment of, take continuously 3-4 the course for the treatment of according to the state of an illness, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, Outcome measure:
Effective: the cardiac distresses such as body constitution strengthens, feeling of oppression and pain in the chest are substantially alleviated, and the visible blood supply of cardiac muscle of electrocardiogram is obviously improved；
Effective: the cardiac distresses such as body constitution strengthens, feeling of oppression and pain in the chest are alleviated to some extent；
Invalid: all diseases are unchanged.
4, therapeutic outcome:
Effective 55 examples, effective 39 examples, invalid 6 examples, total effective rate is 94%.
It is exemplified below a model case:
Wang, man, 62 years old, patient's private prosecution 4+ before being admitted to hospital begins to occur sensation of oppression over the chest with shortness of breath and dizziness without obvious cause, time with cardiopalmus, can aggravate during fatigue, can alleviating through having a rest, my Out-patient Department of once repeatedly seeing a doctor is surveyed blood and is found hypertension, reaches as high as 210/110mmHg, look into electrocardiogram prompting " deficiency myocardial blood supply ", diagnosis is " coronary heart disease, essential hypertension ", gives blood pressure lowering, expands the Western medicine oral medications such as blood vessel, symptom all can be alleviated, but is prone to repeatedly.Within nearly 5 days, increase the weight of earlier above without obvious cause sense symptom, chest dull pain, time when making only, companion's shortness of breath and palpitation, has a dizzy spell, especially with obvious after activity, but fearless cold heating, headache vomiting, dyspnea, abdominal pain and distension, cough and expectoration, deafness and tinnitus, aphasia hemiplegia etc., not giving treatment outside institute, my Out-patient Department of today again seeing a doctor, outpatient service is intended " coronary heart disease, essential hypertension " and is hospitalized and be admitted to hospital.Under occasion: sensation of oppression and faint pain in the chest, time when making only, shortness of breath and palpitation, tiredness with no desire to speak, lustreless complexion, have a dizzy spell, meet labor what for, two just adjust.Taking Chinese medicine preparation of the present invention subsequently, after taking 3 courses for the treatment of, the cardiac distress such as feeling of oppression and pain in the chest is substantially alleviated, and the visible blood supply of cardiac muscle of electrocardiogram is obviously improved, and after continuing to take 1 course for the treatment of, times for spraying reduces by half and adheres to long-term taking, does not occur obvious disease so far.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine preparation treating coronary heart disease, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 10 parts, Radix Codonopsis 10 parts, Radix Notoginseng 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Bupleuri 5 parts, Rhizoma Chuanxiong 5 parts, 5 parts of Poria, Radix Ophiopogonis 3 parts, Fructus Lycii 2 parts, Radix Polygalae 3 parts, Rhizoma Alismatis 5 parts, Fructus Crataegi 1 part, Oletum Trogopterori 1 part and the Rhizoma Anemarrhenae 2 parts.
Embodiment 2:
: a kind of Chinese medicine preparation treating coronary heart disease, according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 15 parts, Radix Codonopsis 15 parts, Radix Notoginseng 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Bupleuri 8 parts, Rhizoma Chuanxiong 8 parts, 8 parts of Poria, Radix Ophiopogonis 5 parts, Fructus Lycii 3 parts, Radix Polygalae 5 parts, Rhizoma Alismatis 10 parts, Fructus Crataegi 2 parts, Oletum Trogopterori 2 parts and the Rhizoma Anemarrhenae 3 parts.
Embodiment 3:
Formula described in embodiment 1 prepares the Chinese medicine preparation for the treatment of coronary heart disease in accordance with the following methods: weighs raw material of Chinese medicine according to formula and joins in container, add water and cover powder immersion 10 minutes, add water and do not have powder 3 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, take filtrate；Then adding water and do not have powder 3 centimetres, decoct with high heat and use slow fire boiling again instead 15 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
Embodiment 4:
Formula described in embodiment 2 prepares the Chinese medicine preparation for the treatment of coronary heart disease in accordance with the following methods: weighs raw material of Chinese medicine according to formula and joins in container, add water and cover powder immersion 20 minutes, add water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 30 minutes to boiling, take filtrate；Then adding water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
Claims (4)
1. the Chinese medicine preparation treating coronary heart disease, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 10～15 parts, Radix Codonopsis 10～15 parts, Radix Notoginseng 15～20 parts, Radix Salviae Miltiorrhizae 15～20 parts, Radix Bupleuri 5～8 parts, Rhizoma Chuanxiong 5～8 parts, 5～8 parts of Poria, Radix Ophiopogonis 3～5 parts, Fructus Lycii 2～3 parts, Radix Polygalae 3～5 parts, Rhizoma Alismatis 5～10 parts, Fructus Crataegi 1～2 part, Oletum Trogopterori 1～2 part and the Rhizoma Anemarrhenae 2～3 parts.
2. a kind of Chinese medicine preparation treating coronary heart disease according to claim 1, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 10 parts, Radix Codonopsis 10 parts, Radix Notoginseng 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Bupleuri 5 parts, Rhizoma Chuanxiong 5 parts, 5 parts of Poria, Radix Ophiopogonis 3 parts, Fructus Lycii 2 parts, Radix Polygalae 3 parts, Rhizoma Alismatis 5 parts, Fructus Crataegi 1 part, Oletum Trogopterori 1 part and the Rhizoma Anemarrhenae 2 parts.
3. a kind of Chinese medicine preparation treating coronary heart disease according to claim 1, it is characterized in that according to parts by weight meter, formulated by following raw material of Chinese medicine: Radix Ginseng Rubra 15 parts, Radix Codonopsis 15 parts, Radix Notoginseng 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Bupleuri 8 parts, Rhizoma Chuanxiong 8 parts, 8 parts of Poria, Radix Ophiopogonis 5 parts, Fructus Lycii 3 parts, Radix Polygalae 5 parts, Rhizoma Alismatis 10 parts, Fructus Crataegi 2 parts, Oletum Trogopterori 2 parts and the Rhizoma Anemarrhenae 3 parts.
4. the preparation method of the Chinese medicine preparation of the treatment coronary heart disease described in a claim 1, it is characterized in that preparing in accordance with the following methods: weigh raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10～20 minutes, add water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 20～30 minutes to boiling, take filtrate；Then adding water and do not have powder 3～5 centimetres, decoct with high heat and use slow fire boiling again instead 15～20 minutes to boiling, then removing slag takes filtrate, and twice filtrate merges.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547519A (en) * | 2014-12-26 | 2015-04-29 | 青岛市市立医院 | Traditional Chinese medicine preparation for treating coronary heart disease and preparation method of traditional Chinese medicine preparation |
| CN113117017A (en) * | 2019-12-30 | 2021-07-16 | 睿特环中医药科技发展有限公司 | A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method |
-
2014
- 2014-12-11 CN CN201410771373.9A patent/CN105726932A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547519A (en) * | 2014-12-26 | 2015-04-29 | 青岛市市立医院 | Traditional Chinese medicine preparation for treating coronary heart disease and preparation method of traditional Chinese medicine preparation |
| CN113117017A (en) * | 2019-12-30 | 2021-07-16 | 睿特环中医药科技发展有限公司 | A Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, and its preparation method |
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