CN106138651A - A kind of anti-inflammation liquid and preparation method thereof - Google Patents
A kind of anti-inflammation liquid and preparation method thereof Download PDFInfo
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Abstract
The present invention provides a kind of anti-inflammation liquid and preparation method thereof, belongs to Chinese drug preparation technique field.The effective ingredient of anti-inflammation liquid of the present invention consist of Herba Menthae, Herba Houttuyniae, eucalyptus leaves, Folium Artemisiae Argyi, Bulbus Allii, Aloe, Fructus Citri Limoniae, Radix Notoginseng, Cacumen Platycladi, Herba Pteridis Multifidae, Herba Scutellariae Barbatae, Herba Catharanthi Rosei, put into above-mentioned raw materials in deionized water to smash and destroy cell wall with cellulase, then refilter with alcohol extraction effective ingredient, it is eventually adding preservative, obtains required anti-inflammation liquid.Anti-inflammation liquid of the present invention not only has antibacterial, antiviral, an effect of raising immunity of organisms, also removing heat from blood, hemostasis, wind-damp dispelling, dissipate toxic swelling, relieveing pain and refreshing, promotion wound healing restore effect of preventing from scar.
Description
[technical field]
The present invention relates to Chinese drug preparation technique field, be specifically related to a kind of anti-inflammation liquid and preparation method thereof.
[background technology]
Inflammation is the most common and important basic pathology process, and the trauma infection contamination of body surface and dermatitis belong to common inflammation
Disease.Inflammation, it is simply that " inflammation " described in people at ordinary times is body for a kind of defense reaction stimulated, show as red, swollen, hot,
Pain and dysfunction, can be to infect the infective inflammation caused, it is also possible to be not due to infect the non-infectious inflammation caused.
Clinical treatment wound scytitis uses povidone iodine, iodine tincture, ethanol etc. to carry out simple antiinflammatory substantially, existing market
The most popular upper antiphlogistine, anti-inflammation liquid have a variety of, and injuring dermatitis has certain curative effect outward for certain part cream, liquid, but right
Severe trauma and dermatitis are just without therapeutic effect.Chinese invention " a kind of aloe antisepsis and anti-inflammation liquor ", publication number 103550474A is open
A kind of antiseptic anti-inflammatory of Aloe original juice, Herba Taraxaci, Flos Lonicerae and normal saline；Chinese invention " a kind of pain relieving
Anti-inflammation liquid ", publication number 102038717A is for the anti-inflammation liquid of toothache；These antiinflammatory unguentum and antiinflammatory liquid have respective disappearing
Scorching effect, but for some the more serious outer dermatitis that injures of ratio, effect is the most obvious.
In order to solve the inflammation of skin surface local, manufacture a kind of Chinese herbal medicine for external use formula, thus reach preferably to treat
Effect, is current urgent problem.
[summary of the invention]
The goal of the invention of the present invention is: for the problem of above-mentioned existence, it is provided that a kind of anti-inflammation liquid and preparation method thereof, this
Invention, by 12 kinds of Chinese medicine reasonable compatibilities, utilizes the fresh book on Chinese herbal medicine of each Chinese medicinal plant as raw material, carries out broken and use ethanol
The mode lixiviating effective components extracted, anti-inflammation liquid of the present invention has antibacterial, antiviral, effect of raising immunity of organisms, moreover it is possible to cool
Blood, hemostasis, wind-damp dispelling, dissipate toxic swelling, relieveing pain and refreshing, and there is the effect promoting that wound healing restores preventing from scar.
To achieve these goals, the technical solution used in the present invention is as follows:
A kind of anti-inflammation liquid, described anti-inflammation liquid is made up of the raw material of following weight portion: Herba Menthae 4000～6000 parts, Herba Houttuyniae
4500～6500 parts, Aloe 5000～6600 parts, Fructus Citri Limoniae 6000～8000 parts, eucalyptus leaves 3500～5500 parts, Folium Artemisiae Argyi 3000～
5000 parts, Cacumen Platycladi 5000～7000 parts, Herba Pteridis Multifidae 3000～4000 parts, Herba Scutellariae Barbatae 2000～3600 parts, Herba Catharanthi Rosei 2500～
3500 parts, Radix Notoginseng 600～800 parts, Bulbus Allii 200～400 parts, ethanol 15000～30000 parts, cellulase 30～50 parts, preservative
40～60 parts, deionized water 8000～10000 parts；
Wherein, all botanical herbses are fresh.
Further, described a kind of anti-inflammation liquid is made up of the raw material of following weight portion: Herba Menthae 4500～5500 parts, Herba Houttuyniae
5000～6000 parts, Aloe 5400～6200 parts, Fructus Citri Limoniae 6500～7500 parts, eucalyptus leaves 4000～5000 parts, Folium Artemisiae Argyi 3500～
4500 parts, Cacumen Platycladi 5500～6500 parts, Herba Pteridis Multifidae 3200～3800 parts, Herba Scutellariae Barbatae 2400～3200 parts, Herba Catharanthi Rosei 2800～
3200 parts, Radix Notoginseng 650～750 parts, Bulbus Allii 250～350 parts, ethanol 18000～26000 parts, cellulase 35～45 parts, preservative
45～55 parts, deionized water 8500～9500 parts；
Wherein, all botanical herbses are fresh.
Further, described a kind of anti-inflammation liquid is made up of the raw material of following weight portion: Herba Menthae 5000 parts, Herba Houttuyniae 5500
Part, Aloe 5800 parts, 7000 parts of Fructus Citri Limoniae, eucalyptus leaves 4500 parts, Folium Artemisiae Argyi 4000 parts, Cacumen Platycladi 6000 parts, Herba Pteridis Multifidae 3500 parts, half
Branch 2800 parts of lotus, Herba Catharanthi Rosei 3000 parts, 700 parts of Radix Notoginseng, Bulbus Allii 300 parts, ethanol 20000 parts, cellulase 40 parts, preservative 50
Part, deionized water 9000 parts；
Wherein, all botanical herbses are fresh.
According to the manufacture method of a kind of anti-inflammation liquid described in above-mentioned formula, comprise the following steps:
(1) various raw material is weighed by weight；
(2) by Herba Menthae, Herba Houttuyniae, eucalyptus leaves, Folium Artemisiae Argyi, Bulbus Allii, Aloe, Fructus Citri Limoniae, Radix Notoginseng, Cacumen Platycladi, Herba Pteridis Multifidae, Herba Scutellariae Barbatae,
Herba Catharanthi Rosei mixes, and adds ethanol, is then battered down to pulp-like filter and remove residue with pulverizer, takes filter pulp standby
With；
(3) after cellulase being added the slurry in step (2) stirring, after heated and stirred 6～10h；
(4) ethanol is poured in the slurry of step (3), continues after stirring at normal temperature 2～4h, put in centrifuge with 200～
400r/min centrifugation 20～30min；
(5) by the liquid filter paper filtering after pulp centrifuged separation in step (4), filtrate is taken standby；
(6) in filtrate in step (5), add preservative, reheat and be stirred continuously till dissolving, obtain required
Anti-inflammation liquid.
More preferably, the heating-up temperature of step (3) and step (6) is 30～50 DEG C, and cellulase is lived in this temperature province
Property the strongest, can effectively destroy the cell wall of plant cell, make the effective ingredient dissolution in plant, preservative can at 30～50 DEG C
To accelerate to dissolve and can guarantee that the effective ingredient in anti-inflammation liquid was not because temperature degeneration was lost efficacy.
More preferably, described preservative is one or more mixing in sorbic acid, sodium benzoate, salicylic acid, and preservative exists
In anti-inflammation liquid the most inhibited to yeast, mycete and many microorganisms, be high effect nontoxic Antisepticize and mildew preventive, additionally to skin
The antibacterial on surface and virus also have the strongest rejection ability.
Concrete effect of the various raw materials of the present invention is as follows:
Herba Menthae: acrid in the mouth, cool in nature, return liver, lung meridian.Dispelling wind and heat pathogens, the clear profit head, sore-throat relieving rash, soothing the liver circulation of qi promoting, for the sense of taste
Neural and olfactory nerves has the effect of excitement.
Herba Houttuyniae: acrid in the mouth, cold, return lung meridian.Can heat-clearing and toxic substances removing, detumescence treatment skin ulcer, promoting urination to remove dampness, clearing away heat to cure dysentery, stomach invigorating
Help digestion, with controlling excess-heat, pyretic toxicity, damp, disease heat be suffer from lung abscess, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc..Modern pharmacology
Experiment shows, this product has the effect such as antibacterial, antiviral, raising immunity of organisms, diuresis.
Aloe: bitter in the mouth, cold in nature, nontoxic, return liver, large intestine channel.The Kallidin I enzyme of Aloe is combined with vasotonia and can be resisted
Inflammation.The especially polysaccharide of Aloe can strengthen the human body resistance to disease, Aloin A, wound hormone and polysaccharide peptide manna
Etc. (Ke-2) there is viral infection resisting, the effect promoting wound healing to restore, there are anti-inflammation and sterilization, clearing heat for detumescence, softening skin, guarantor
Hold the function of cell viability, curdlan combine with 1-decene-1 also have healing wounds activity, therefore, it is that one treats wound
(hemorrhagic wound, non-hemorrhagic wound) does not stay the preferable medicine of scar.
Fructus Citri Limoniae: sweet in the mouth, acid, cold in nature, return liver, stomach warp.Fructus Citri Limoniae can be alleviated calcium ion promote blood with prevention and cure of cardiovascular disease
The effect of liquid solidification, citric acid has contraction, reinforcement blood capillary, reduces permeability, raising coagulation function and platelet counts
Effect, can shorten clotting time and bleeding time 31%～71%, have anastalsis.
Eucalyptus leaves: bitter in the mouth, warm in nature, return lung meridian.Cure cold, influenza, dysentery, enteritis, arthralgia, cystitis, scald, scabies
Tinea, erysipelas, neurodermatitis, eczema, ulcerative carbuncle toxic swelling, there is the strongest sterilizing ability, wherein the eucalyptus globulus quintessence oil in eucalyptus leaves is refrigerant
Pleasant breath, makes that people is in high spirits, clearheaded, attention is concentrated.
Folium Artemisiae Argyi: bitter in the mouth is pungent, warm in nature, return spleen, liver, kidney channel.The pharmacological research of modern medicine shows that Folium Artemisiae Argyi is that a kind of wide spectrum resists
Bacterium antiviral drug, it has suppression and lethal effect to a lot of viruses and antibacterial.
Cacumen Platycladi: bitter in the mouth is pungent, cold in nature puckery, GUIXIN, liver, large intestine channel.There is removing heat from blood, hemostasis, wind-damp dispelling, dissipate toxic swelling.Control haematemesis,
Epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, cough, erysipelas, mumps, the merit of scald
Effect.
Herba Pteridis Multifidae: mildly bitter flavor, cool in nature, return liver, kidney, large intestine channel.Having clearing away heat-damp and promoting diuresis, detoxify dysentery relieving, cooling blood for hemostasis effect,
It is mainly used in dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication；External
Control traumatic hemorrhage, burn and scald.
Herba Scutellariae Barbatae: acrid in the mouth；Bitter；Cold in nature, return lung, liver, kidney channel.Heat-clearing and toxic substances removing；Dissipating blood stasis stops blooding；Inducing diuresis to remove edema.
Herba Catharanthi Rosei: micro-hardship is cool.Poisonous.Return liver, lung meridian.All herbal medicine can pain relieving, antiinflammatory, sleeping, relieving constipation and diuresis etc..
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature, return liver, stomach, the heart, lung, large intestine channel.There is hemostasis, dissipate blood, the effect of analgesic therapy.Three
Seven have titles of " hemostasis god's medicine ", dissipating blood stasis blood, hemostasis and do not stay the stasis of blood, to have the stagnant person of the stasis of blood concurrently the most suitable to hemorrhage.Pseudo-ginseng hemostatic effect
Mainly by increasing platelet counts, strengthening platelet function realization, there is stronger anastalsis, to different animals, different
Route of administration, different preparations, all show obvious anastalsis.
Bulbus Allii: acrid in the mouth, warm in nature, return spleen, stomach, lung meridian.Function cures mainly: all have Common Pathogenic dermatophytes in various degree
Inhibitory action, has obviously inhibitory action to Candida albicans, neogenesis cryptococcus, to pyococcus, tubercule bacillus, dysentery
Shigella, Bacillus typhi, Salmonella paratyphi, vibrio cholera the most all have an inhibitory action, and to green grass or young crops, chain, chlorine, chlortetracycline drug resistance
Antibacterial, garlic preparation also has inhibitory action.
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows:
(1) present invention passes through 12 kinds of Chinese medicine reasonable compatibilities, utilizes the fresh book on Chinese herbal medicine of each Chinese medicinal plant as raw material, carries out
Crush and use the mode lixiviating effective components of alcohol extraction, have antibacterial, antiviral, raising immunity of organisms, have removing heat from blood,
Hemostasis, wind-damp dispelling, scattered toxic swelling, relieveing pain and refreshing, effect of promotion wound healing recovery preventing from scar.
(2) Bulbus Allii of present invention use, Folium Artemisiae Argyi, eucalyptus leaves, Herba Houttuyniae have the strongest antibiotic and sterilizing ability, to suppurative ball
Bacterium, tubercule bacillus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, vibrio cholera the most all have inhibitory action, and to nerve
Dermatitis also has preferable curative effect.
(3) Radix Notoginseng, Herba Scutellariae Barbatae, Herba Catharanthi Rosei, Cacumen Platycladi, Herba Pteridis Multifidae and the Fructus Citri Limoniae that the present invention uses has the best coagulating
Blood, hemostasis and dissipating blood stasis function, especially Radix Notoginseng, by increasing platelet counts, strengthening platelet function realization, have stronger stopping
Blood effect, the citric acid in Fructus Citri Limoniae has contraction, reinforcement blood capillary, reduces permeability, improves coagulation function and platelet counts
Effect.
(4) Herba Menthae that the present invention uses has relieveing pain and refreshing effect, reduces wound or the dermatitis stimulation to patient skin, subtracts
Few patient scratches affected part with hands, the superinfection caused.
(5) present invention uses cellulase, can effectively destroy the cell wall of plant cell, make the effective ingredient in plant
Dissolution, can be the ethanol effective ingredient that extracts in Chinese medicine faster.
(6) present invention uses the method effective component extracting that fresh Chinese medicine is pulverized, and protects Chinese medicinal plant to greatest extent
In effective ingredient be not destroyed, play drug effect greatly.
In a word, each crude drug of the present invention through scientific compatibility, and the synergism of ethanol, have antibacterial, antiviral,
Improve immunity of organisms, have removing heat from blood, hemostasis, wind-damp dispelling, scattered toxic swelling, relieveing pain and refreshing, promotion wound healing to restore preventing from scar
Effect.
[detailed description of the invention]
Below by way of specific embodiment, the invention will be further described.
Embodiment 1
A kind of anti-inflammation liquid, is made up of the raw material of following weight portion: Herba Menthae 5000 parts, Herba Houttuyniae 5500 parts, Aloe 5800 parts,
7000 parts of Fructus Citri Limoniae, eucalyptus leaves 4500 parts, Folium Artemisiae Argyi 4000 parts, Cacumen Platycladi 6000 parts, Herba Pteridis Multifidae 3500 parts, Herba Scutellariae Barbatae 2800 parts, length
Spring flower 3000 parts, 700 parts of Radix Notoginseng, Bulbus Allii 300 parts, ethanol 20000 parts, cellulase 40 parts, preservative 50 parts, deionized water 9000
Part；
Wherein, all botanical herbses are fresh.
According to the manufacture method of a kind of anti-inflammation liquid described in above-mentioned formula, comprise the following steps:
(1) various raw material is weighed by weight；
(2) by Herba Menthae, Herba Houttuyniae, eucalyptus leaves, Folium Artemisiae Argyi, Bulbus Allii, Aloe, Fructus Citri Limoniae, Radix Notoginseng, Cacumen Platycladi, Herba Pteridis Multifidae, Herba Scutellariae Barbatae,
Herba Catharanthi Rosei mixes, and adds ethanol, is then battered down to pulp-like filter and remove residue with pulverizer, takes filter pulp standby
With；
(3) after cellulase being added the slurry in step (2) stirring, heated and stirred 8h；
(4) ethanol is poured in the slurry of step (3), after continuing stirring at normal temperature 3h, put in centrifuge with rotating speed 300r/
Min centrifugation 25min；
(5) by the liquid filter paper filtering after pulp centrifuged separation in step (4), filtrate is taken standby；
(6) in filtrate in step (5), add preservative, reheat and be stirred continuously till dissolving, obtain required
Anti-inflammation liquid.
Wherein, the heating-up temperature of step (3) and step (6) is 40 DEG C, and cellulase activity in this temperature province is the strongest,
Can effectively destroy the cell wall of plant cell, make the effective ingredient dissolution in plant, preservative can accelerate to dissolve at 40 DEG C
And can guarantee that the effective ingredient in anti-inflammation liquid was not because temperature degeneration was lost efficacy；Preservative is in sorbic acid, sodium benzoate, salicylic acid
One or more mixing, preservative is the most inhibited to yeast, mycete and many microorganisms in anti-inflammation liquid, is efficient nothing
Poison Antisepticize and mildew preventive, additionally antibacterial and virus to skin surface also have the strongest rejection ability.
Embodiment 2
A kind of anti-inflammation liquid, is made up of the raw material of following weight portion: Herba Menthae 4000 parts, Herba Houttuyniae 4500 parts, Aloe 5000 parts,
6000 parts of Fructus Citri Limoniae, eucalyptus leaves 3500 parts, Folium Artemisiae Argyi 3000 parts, Cacumen Platycladi 5000 parts, Herba Pteridis Multifidae 3000 parts, Herba Scutellariae Barbatae 2000 parts, length
Spring flower 2500 parts, 600 parts of Radix Notoginseng, Bulbus Allii 200 parts, ethanol 15000 parts, cellulase 30 parts, preservative 40 parts, deionized water 8000
Part；
Wherein, all botanical herbses are fresh.
According to the manufacture method of a kind of anti-inflammation liquid described in above-mentioned formula, comprise the following steps:
(1) various raw material is weighed by weight；
(2) by Herba Menthae, Herba Houttuyniae, eucalyptus leaves, Folium Artemisiae Argyi, Bulbus Allii, Aloe, Fructus Citri Limoniae, Radix Notoginseng, Cacumen Platycladi, Herba Pteridis Multifidae, Herba Scutellariae Barbatae,
Herba Catharanthi Rosei mixes, and adds ethanol, is then battered down to pulp-like filter and remove residue with pulverizer, takes filter pulp standby
With；
(3) after cellulase being added the slurry in step (2) stirring, after heated and stirred 6h；
(4) ethanol is poured in the slurry of step (3), after continuing stirring at normal temperature 2h, put in centrifuge with rotating speed 200r/
Min centrifugation 20min；
(5) by the liquid filter paper filtering after pulp centrifuged separation in step (4), filtrate is taken standby；
(6) in filtrate in step (5), add preservative, reheat and be stirred continuously till dissolving, obtain required
Anti-inflammation liquid.
Wherein, the heating-up temperature of step (3) and step (6) is 30 DEG C, and cellulase activity in this temperature province is the strongest,
Can effectively destroy the cell wall of plant cell, make the effective ingredient dissolution in plant, preservative can accelerate to dissolve at 30 DEG C
And can guarantee that the effective ingredient in anti-inflammation liquid was not because temperature degeneration was lost efficacy；Preservative is in sorbic acid, sodium benzoate, salicylic acid
One or more mixing, preservative is the most inhibited to yeast, mycete and many microorganisms in anti-inflammation liquid, is efficient nothing
Poison Antisepticize and mildew preventive, additionally antibacterial and virus to skin surface also have the strongest rejection ability.
Embodiment 3
A kind of anti-inflammation liquid, is made up of the raw material of following weight portion: Herba Menthae 6000 parts, Herba Houttuyniae 6500 parts, Aloe 6600 parts,
8000 parts of Fructus Citri Limoniae, eucalyptus leaves 5500 parts, Folium Artemisiae Argyi 5000 parts, Cacumen Platycladi 7000 parts, Herba Pteridis Multifidae 4000 parts, Herba Scutellariae Barbatae 3600 parts, length
Spring flower 3500 parts, 800 parts of Radix Notoginseng, Bulbus Allii 400 parts, ethanol 30000 parts, cellulase 50 parts, preservative 60 parts, deionized water
10000 parts；
Wherein, all botanical herbses are fresh.
According to the manufacture method of a kind of anti-inflammation liquid described in above-mentioned formula, comprise the following steps:
(1) various raw material is weighed by weight；
(2) by Herba Menthae, Herba Houttuyniae, eucalyptus leaves, Folium Artemisiae Argyi, Bulbus Allii, Aloe, Fructus Citri Limoniae, Radix Notoginseng, Cacumen Platycladi, Herba Pteridis Multifidae, Herba Scutellariae Barbatae,
Herba Catharanthi Rosei mixes, and adds ethanol, is then battered down to pulp-like filter and remove residue with pulverizer, takes filter pulp standby
With；
(3) after cellulase being added the slurry in step (2) stirring, heated and stirred 10h；
(4) ethanol is poured in the slurry of step (3), after continuing stirring at normal temperature 4h, put in centrifuge with rotating speed 400r/
Min centrifugation 20～30min；
(5) by the liquid filter paper filtering after pulp centrifuged separation in step (4), filtrate is taken standby；
(6) in filtrate in step (5), add preservative, reheat and be stirred continuously till dissolving, obtain required
Anti-inflammation liquid.
Wherein, the heating-up temperature of step (3) and step (6) is 30～50 DEG C, and cellulase is activity in this temperature province
The strongest, can effectively destroy the cell wall of plant cell, make the effective ingredient dissolution in plant, preservative is permissible at 30～50 DEG C
Accelerate to dissolve and can guarantee that the effective ingredient in anti-inflammation liquid was not because temperature degeneration was lost efficacy；Preservative is sorbic acid, sodium benzoate, water
One or more mixing in poplar acid, preservative is the most inhibited to yeast, mycete and many microorganisms in anti-inflammation liquid,
Being high effect nontoxic Antisepticize and mildew preventive, additionally antibacterial and virus to skin surface also have the strongest rejection ability.
Embodiment 4
A kind of anti-inflammation liquid, is made up of the raw material of following weight portion: Herba Menthae 4500 parts, Herba Houttuyniae 5000 parts, Aloe 5400 parts,
6500 parts of Fructus Citri Limoniae, eucalyptus leaves 4000 parts, Folium Artemisiae Argyi 3500 parts, Cacumen Platycladi 5500 parts, Herba Pteridis Multifidae 3200 parts, Herba Scutellariae Barbatae 2400 parts, length
Spring flower 2800 parts, 650 parts of Radix Notoginseng, Bulbus Allii 250 parts, ethanol 18000 parts, cellulase 35 parts, preservative 45 parts, deionized water 8500
Part；
Wherein, all botanical herbses are fresh.
Embodiment 5
A kind of anti-inflammation liquid, is made up of the raw material of following weight portion: Herba Menthae 5500 parts, Herba Houttuyniae 6000 parts, Aloe 6200 parts,
7500 parts of Fructus Citri Limoniae, eucalyptus leaves 5000 parts, Folium Artemisiae Argyi 4500 parts, Cacumen Platycladi 6500 parts, Herba Pteridis Multifidae 3800 parts, Herba Scutellariae Barbatae 3200 parts, length
Spring flower 3200 parts, 750 parts of Radix Notoginseng, Bulbus Allii 350 parts, ethanol 26000 parts, cellulase 45 parts, preservative 55 parts, deionized water 9500
Part；
Wherein, all botanical herbses are fresh.
Compliance test result:
Clinical observation material:
1, crowd selects:
Select skin injury patient 100 example to carry out compliance test result observation, and patient is divided into two groups, often organize 50 people.Wherein,
Experimental group: male 26 examples, women 24 example, in age 20-58 year, 35 years old mean age, patient wound starts the symptoms such as inflammation patient, right
According to group symptom basically identical, wherein, matched group: male 25 examples, women 25 example, age 21-56 year, 33 years old mean age, for ease of
Contrast, the patient of matched group does not carries out any process to wound, and other situations are basically identical.
2, the patient of experimental group uses anti-inflammation liquid of the present invention, smears a wound at interval of 3h, smears 5～6 every day, no
Wrapping, persistently smears one week.
3, Outcome measure:
Observe patient wound whether inflammation, form a scab, heal, cicatrix state.
4, verification the verifying results such as following table:
Upper result shows, the wound normal healing of matched group is of long duration, and easy infection inflammation；Experimental group each side state and
Parameter is superior to matched group, drips the wound inflammation that can effectively control traumatic patient with the anti-inflammation liquid of the present invention, and can obtain quickly
Antiinflammatory, incrustation healing, and in one month, cicatrix starts to eliminate.
Claims (6)
1. an anti-inflammation liquid, it is characterised in that: described anti-inflammation liquid is made up of the raw material of following weight portion: Herba Menthae 4000～6000
Part, Herba Houttuyniae 4500～6500 parts, Aloe 5000～6600 parts, Fructus Citri Limoniae 6000～8000 parts, eucalyptus leaves 3500～5500 parts, Chinese mugwort
Leaf 3000～5000 parts, Cacumen Platycladi 5000～7000 parts, Herba Pteridis Multifidae 3000～4000 parts, Herba Scutellariae Barbatae 2000～3600 parts, Changchun
Spend 2500～3500 parts, Radix Notoginseng 600～800 parts, Bulbus Allii 200～400 parts, ethanol 15000～30000 parts, cellulase 30～50
Part, preservative 40～60 parts, deionized water 8000～10000 parts；
Wherein, all botanical herbses are fresh goods.
A kind of anti-inflammation liquid, it is characterised in that: described anti-inflammation liquid is by the raw material system of following weight portion
Become: Herba Menthae 4500～5500 parts, Herba Houttuyniae 5000～6000 parts, Aloe 5400～6200 parts, Fructus Citri Limoniae 6500～7500 parts, Eucalyptus
Leaf 4000～5000 parts, Folium Artemisiae Argyi 3500～4500 parts, Cacumen Platycladi 5500～6500 parts, Herba Pteridis Multifidae 3200～3800 parts, Herba Scutellariae Barbatae
2400～3200 parts, Herba Catharanthi Rosei 2800～3200 parts, Radix Notoginseng 650～750 parts, Bulbus Allii 250～350 parts, ethanol 18000～26000
Part, cellulase 35～45 parts, preservative 45～55 parts, deionized water 8500～9500 parts；
Wherein, all botanical herbses are fresh goods.
A kind of anti-inflammation liquid, it is characterised in that: described anti-inflammation liquid is by the raw material system of following weight portion
Become: Herba Menthae 5000 parts, Herba Houttuyniae 5500 parts, Aloe 5800 parts, 7000 parts of Fructus Citri Limoniae, eucalyptus leaves 4500 parts, Folium Artemisiae Argyi 4000 parts, Cacumen Platycladi
6000 parts of leaf, Herba Pteridis Multifidae 3500 parts, Herba Scutellariae Barbatae 2800 parts, Herba Catharanthi Rosei 3000 parts, 700 parts of Radix Notoginseng, Bulbus Allii 300 parts, ethanol 20000
Part, cellulase 40 parts, preservative 50 parts, deionized water 9000 parts；
Wherein, all botanical herbses are fresh goods.
4. according to the manufacture method of a kind of anti-inflammation liquid according to any one of claim 1-3, it is characterised in that: include following step
Rapid:
(1) various raw material is weighed by weight；
(2) by Herba Menthae, Herba Houttuyniae, eucalyptus leaves, Folium Artemisiae Argyi, Bulbus Allii, Aloe, Fructus Citri Limoniae, Radix Notoginseng, Cacumen Platycladi, Herba Pteridis Multifidae, Herba Scutellariae Barbatae, Changchun
Flower mixes, and adds ethanol, is then battered down to pulp-like filter and remove residue with pulverizer, takes filter pulp standby；
(3) after cellulase being added the slurry in step (2) stirring, heated and stirred 6～10h；
(4) ethanol is poured in the slurry of step (3), continues after stirring at normal temperature 2～4h, put in centrifuge with rotating speed 200～
400r/min centrifugation 20～30min；
(5) by the liquid filter paper filtering after pulp centrifuged separation in step (4), filtrate is taken standby；
(6) in filtrate in step (5), add preservative, reheat and be stirred continuously till dissolving, obtain required antiinflammatory
Liquid.
A kind of manufacture method of liquor-rhinitis, it is characterised in that: step (3) and the heating of step (6)
Temperature is 30～50 DEG C.
A kind of manufacture method of liquor-rhinitis, it is characterised in that: described preservative is sorbic acid, benzene
One or more mixing in sodium formate, salicylic acid.
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| Application Number | Priority Date | Filing Date | Title |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550474A (en) * | 2013-11-04 | 2014-02-05 | 牛永 | Aloe antisepsis and anti-inflammation liquor |
| CN103961454A (en) * | 2014-05-28 | 2014-08-06 | 刘敏 | Sterilizing anti-inflammation solution |
-
2016
- 2016-07-28 CN CN201610602616.5A patent/CN106138651A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550474A (en) * | 2013-11-04 | 2014-02-05 | 牛永 | Aloe antisepsis and anti-inflammation liquor |
| CN103961454A (en) * | 2014-05-28 | 2014-08-06 | 刘敏 | Sterilizing anti-inflammation solution |
Non-Patent Citations (1)
| Title |
|---|
| 浙江省杭州中医院 五官科: "鼻通一号治疗鼻炎279例报告", 《新医学》 * |
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Application publication date: 20161123 |