CN106109617A - A kind of refined even electuary and preparation method thereof treating diabetes - Google Patents
A kind of refined even electuary and preparation method thereof treating diabetes Download PDFInfo
- Publication number
- CN106109617A CN106109617A CN201610677870.1A CN201610677870A CN106109617A CN 106109617 A CN106109617 A CN 106109617A CN 201610677870 A CN201610677870 A CN 201610677870A CN 106109617 A CN106109617 A CN 106109617A
- Authority
- CN
- China
- Prior art keywords
- lianye
- powder
- refined
- radix paeoniae
- paeoniae rubra
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of refined even electuary and preparation method thereof treating diabetes, be made up of refined even powder, Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts, the weight ratio of refined even powder, river Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts is 1 0.3 0.8 0.2 0.3.The primary medicinal component berberine of refined company can promote that insulin releasing increases, suppression gluconeogenesis, promotes glycolysis, has the regeneration function promoting beta Cell of islet simultaneously, its mechanism of action is not direct blood sugar lowering, but fundamentally solves the problem that human insulin lacks.Radix Paeoniae Rubra can improve insulin resistant, reduces blood glucose.Both share, and can effectively treat diabetes.The superfine powder flour using refined company and Radix Paeoniae Rubra is raw material, can improve the absorption of beneficiating ingredient.Ya Lianye Aqueous extracts is used together with source, containing essentially identical composition, to improve drug effect with refined as the solution of pelletize, Ya Lianye.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of refined even electuary and preparation method thereof treating diabetes.
Background technology
" refined company ", Chinese herbal medicine title, a kind of Rhizoma Coptidis, have another name called mount emei company, Jiading company, Ci Gailian.For plant triangle
The dry rhizome of leaf Rhizoma Coptidis.2008, audit through China national State Administration of Quality Supervision, Inspection and Quarantine, determine that " refined company " is implemented national geography mark produces
Product are protected.
Refined company, containing the alkaloid such as berberine, coptisine, 13-methyl-.psi.-coptisine., palmatine, can control acute conjunctivitis, acute
The diseases such as bacillary dysentery, acute gastroenteritis, haematemesis, carbuncle furuncle infections.
Heat clearing and damp drying effect: for diarrhea due to damp-heat, dysentery etc., can be alone or be Xianglian Wan；Treatment jaundice due to damp-heat such as Herba Artemisiae Scopariae
Artemisia soup.
Pathogenic fire purging effect: for earnest tired, the unconsciousness and delirium of the agitation sleeplessness of hyperactivity of heart-fire or the height of epidemic febrile disease, such as coptis detoxifcation
Soup；If the treatment deficiency of YIN, the dysphoria and insomnia of blood deficiency, such as Chinese goldthread colla corii asini decoction；The treatment haematemesis of bleeding due to blood-heat, epistaxis, such as XIEXIN TANG；Stomach
Vomiting due to heat is told, such as Zuojin Wan.
Detoxicating functions: be used for treating skin infection, aphtha of the mouth and tongue, laryngopharynx swelling and pain, for oral administration, external；Decoct juice eye dripping also can control
Treat conjunctival congestion and swelling pain etc..
Diabetes are one group of metabolic diseases being characterized with hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or
Its biological agent is impaired, or both have concurrently and cause.Long-standing hyperglycemia during diabetes, causes various tissue, particularly eye,
Kidney, heart, blood vessel, neural chronic lesion, dysfunction.
Summary of the invention
It is an object of the present invention to provide a kind of refined even electuary treating diabetes.
The technical scheme is that a kind of refined even electuary treating diabetes, by refined even powder, Radix Paeoniae Rubra powder and Ya Lianye water
Extract forms, and the weight ratio of refined even powder, river Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts is 1 0.3-0.8 0.2-0.3.
Further, refined even powder is the superfine powder flour of refined even tuber, particle diameter 5-8um.
Further, river Radix Paeoniae Rubra powder is the dry root superfine powder flour of river Radix Paeoniae Rubra, particle diameter 5-8um.
Further, the preparation method of Ya Lianye Aqueous extracts is: is cleaned by the Ya Lianye clear water of fresh harvesting, adds refined
Even the water of leaf weight 3-5 times decocts, and is concentrated into 2 times of Ya Lianye weight, filtration i.e. get Ya Lianye Aqueous extracts.
The invention also discloses the preparation method of a kind of refined even electuary treating diabetes, comprise the following steps:
(1) tuber of refined company, river Radix Paeoniae Rubra root being cleaned up, be cut into the granule that particle diameter is 0.5-1cm, natural drying is to containing
Water rate is less than 60%；
(2) refined even granule and the river Radix Paeoniae Rubra granule after dry in the sun is mixed by weight ratio, put in super micron mill and pulverize；
(3) being cleaned by the Ya Lianye clear water of fresh harvesting, the water adding Ya Lianye weight 3-5 times decocts, and concentrates
To 2 times of Ya Lianye weight, filtration i.e. get Ya Lianye Aqueous extracts；
(4) step (2) is pulverized the refined even Ya Lianye Aqueous extracts that powder and Radix Paeoniae Rubra powder obtain with step (3) obtained to mix,
Pelletize, i.e. get Ya Lian electuary.
The present invention compared with prior art has the advantage that
1, the primary medicinal component berberine of refined company can promote that insulin releasing increases, and suppresses gluconeogenesis, promotes sugar ferment
Solving, have the regeneration function promoting beta Cell of islet simultaneously, its mechanism of action is not direct blood sugar lowering, but fundamentally solves people
The insulinopenic problem of body.Radix Paeoniae Rubra can improve insulin resistant, reduces blood glucose.Both share, and can effectively treat diabetes.
2, the superfine powder flour using refined company and Radix Paeoniae Rubra is raw material, can improve the absorption of beneficiating ingredient.
3, using Ya Lianye Aqueous extracts as the solution of pelletize, Ya Lianye is with refined together with source, containing essentially identical composition,
Improve drug effect.
Detailed description of the invention
Embodiment 1
A kind of refined even electuary treating diabetes, is made up of refined even powder, Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts, refined even powder, river
The weight ratio of Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts is 1 0.3 0.3.Refined even powder is the superfine powder flour of refined even tuber, particle diameter 5-
8um.River Radix Paeoniae Rubra powder is the dry root superfine powder flour of river Radix Paeoniae Rubra, particle diameter 5-8um.The preparation method of Ya Lianye Aqueous extracts is: will
The Ya Lianye clear water of fresh harvesting is cleaned, and the water adding Ya Lianye weight 3 times decocts, and is concentrated into the 2 of Ya Lianye weight
Times, filtration i.e. get Ya Lianye Aqueous extracts, preparation method, comprise the following steps:
(1) tuber of refined company, river Radix Paeoniae Rubra root being cleaned up, be cut into the granule that particle diameter is 0.5-1cm, natural drying is to containing
Water rate is less than 60%；
(2) refined even granule and the river Radix Paeoniae Rubra granule after dry in the sun is mixed by weight ratio, put in super micron mill and pulverize；
(3) being cleaned by the Ya Lianye clear water of fresh harvesting, the water adding Ya Lianye weight 3-5 times decocts, and concentrates
To 2 times of Ya Lianye weight, filtration i.e. get Ya Lianye Aqueous extracts；
(4) step (2) is pulverized the refined even Ya Lianye Aqueous extracts that powder and Radix Paeoniae Rubra powder obtain with step (3) obtained to mix,
Pelletize, i.e. get Ya Lian electuary.
Embodiment 2
A kind of refined even electuary treating diabetes, is made up of refined even powder, Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts, refined even powder, river
The weight ratio of Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts is 1 0.8 0.2.Refined even powder is the superfine powder flour of refined even tuber, particle diameter 5-
8um.River Radix Paeoniae Rubra powder is the dry root superfine powder flour of river Radix Paeoniae Rubra, particle diameter 5-8um.The preparation method of Ya Lianye Aqueous extracts is: will
The Ya Lianye clear water of fresh harvesting is cleaned, and the water adding Ya Lianye weight 5 times decocts, and is concentrated into the 2 of Ya Lianye weight
Times, filtration i.e. get Ya Lianye Aqueous extracts.Preparation method, comprises the following steps:
(1) tuber of refined company, river Radix Paeoniae Rubra root being cleaned up, be cut into the granule that particle diameter is 0.5-1cm, natural drying is to containing
Water rate is less than 60%；
(2) refined even granule and the river Radix Paeoniae Rubra granule after dry in the sun is mixed by weight ratio, put in super micron mill and pulverize；
(3) being cleaned by the Ya Lianye clear water of fresh harvesting, the water adding Ya Lianye weight 3-5 times decocts, and concentrates
To 2 times of Ya Lianye weight, filtration i.e. get Ya Lianye Aqueous extracts；
(4) step (2) is pulverized the refined even Ya Lianye Aqueous extracts that powder and Radix Paeoniae Rubra powder obtain with step (3) obtained to mix,
Pelletize, i.e. get Ya Lian electuary.
Instructions of taking is: this product 5g of every time taking after mixing it with water ante cibum, three times a day, 30 days is a course for the treatment of.
Case 1
Liu so-and-so, man, 40 years old, peasant, because of polyphagia, polydipsia, become thin 2 months go to a doctor.Patient before 2 months without obvious inducement by
Gradually appetite increases, and by 450g original every day to 550g every day, for up to 800g, and body weight is gradually reduced, body weight in 2 months
Alleviate more than 3kg, occur thirsty simultaneously, like drinking water more, hydrouria.Routine urinalysis: urine protein (-), glucose in urine (++),；Empty
Abdomen blood glucose 10.78mmol/L.It is diagnosed as: type 2 diabetes mellitus.
After taking medicine one week, the symptoms such as patient sleeps, polydipsia, polyuria take a favorable turn.Take medicine half course for the treatment of, patient's " three-many-one-little "
Symptom substantially alleviates.Taking medicine a course for the treatment of, patient's state of an illness is basicly stable.
Case 2
Zeng, female, 51 years old, main cause is thirsty, polydipsia, weak more than 4 years.Go to a doctor to local hospital, look into fasting glucose
8.7mmol/L, is diagnosed as " diabetes ".
Rule is taken the refined even electuary of the present invention and, after 1 month, is looked into fasting glucose 4.9mmol/L, after the meal 3 hours blood glucose
8.1mmol/L.Check on an empty stomach and after the meal 3 hours blood glucose bimester after.Fasting glucose fluctuates between 4.0 6.4mmol/L, after the meal
3 hours blood glucoses fluctuate between 5.5 6.8mmol/L.
Embodiment described above only have expressed the detailed description of the invention of the application, and it describes more concrete and detailed, but also
Therefore the restriction to the application protection domain can not be interpreted as.It should be pointed out that, for those of ordinary skill in the art
For, on the premise of conceiving without departing from technical scheme, it is also possible to make some deformation and improvement, these broadly fall into this
The protection domain of application.
Claims (5)
1. the refined even electuary treating diabetes, it is characterised in that be made up of refined even powder, Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts,
The weight ratio of refined even powder, river Radix Paeoniae Rubra powder and Ya Lianye Aqueous extracts is 1 0.3-0.8 0.2-0.3.
A kind of refined even electuary treating diabetes the most according to claim 1, it is characterised in that refined even powder is refined even tuber
Superfine powder flour, particle diameter 5-8um.
A kind of refined even electuary treating diabetes the most according to claim 1, it is characterised in that river Radix Paeoniae Rubra powder is river Radix Paeoniae Rubra
Dry root superfine powder flour, particle diameter 5-8um.
A kind of refined even electuary treating diabetes the most according to claim 1, it is characterised in that the system of Ya Lianye Aqueous extracts
Preparation Method is: cleaned by the Ya Lianye clear water of fresh harvesting, and the water adding Ya Lianye weight 3-5 times decocts, and is concentrated into
2 times of Ya Lianye weight, filtration i.e. get Ya Lianye Aqueous extracts.
5., according to the preparation method of a kind of refined even electuary treating diabetes described in any one of claim 1-3, its feature exists
In, comprise the following steps:
(1) tuber of refined company, river Radix Paeoniae Rubra root being cleaned up, be cut into the granule that particle diameter is 0.5-1cm, natural drying is to moisture content
Less than 60%；
(2) refined even granule and the river Radix Paeoniae Rubra granule after dry in the sun is mixed by weight ratio, put in super micron mill and pulverize；
(3) being cleaned by the Ya Lianye clear water of fresh harvesting, the water adding Ya Lianye weight 3-5 times decocts, and is concentrated into refined
Even 2 times of leaf weight, filtration i.e. get Ya Lianye Aqueous extracts；
(4) step (2) is pulverized the refined even Ya Lianye Aqueous extracts that powder and Radix Paeoniae Rubra powder obtain with step (3) obtained to mix, pelletize,
I.e. get Ya Lian electuary.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610677870.1A CN106109617A (en) | 2016-08-17 | 2016-08-17 | A kind of refined even electuary and preparation method thereof treating diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610677870.1A CN106109617A (en) | 2016-08-17 | 2016-08-17 | A kind of refined even electuary and preparation method thereof treating diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106109617A true CN106109617A (en) | 2016-11-16 |
Family
ID=57279073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610677870.1A Pending CN106109617A (en) | 2016-08-17 | 2016-08-17 | A kind of refined even electuary and preparation method thereof treating diabetes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106109617A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107213215A (en) * | 2017-05-25 | 2017-09-29 | 西南交通大学 | A kind of purposes of refined company or its processed product |
-
2016
- 2016-08-17 CN CN201610677870.1A patent/CN106109617A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107213215A (en) * | 2017-05-25 | 2017-09-29 | 西南交通大学 | A kind of purposes of refined company or its processed product |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101264217A (en) | Chinese medicine assembly for nourishing yin and tonifying kidney, promoting qi and promoting blood circulation, and relaxing tendons and collaterals | |
| CN101011544A (en) | Gout rapid recovery pill(capsule) and preparation technique thereof | |
| CN106389757B (en) | A kind of pharmaceutical composition and its preparation method and application for treating diabetic nephropathy | |
| CN106138282A (en) | A kind of refined even electuary and preparation method thereof for diabetes patient's regulating lipoid and reducing blood pressure | |
| CN1709302A (en) | Chinese medicine formulation for treating chronic pelvic inflammation and its preparing method | |
| CN104524214B (en) | Treat the Chinese medicine composition and its Chinese medicine preparation, preparation method and application of digestive tract ulcer | |
| CN106109617A (en) | A kind of refined even electuary and preparation method thereof treating diabetes | |
| CN101549098B (en) | Pandan leaf extract for treating gout and preparation method thereof | |
| CN103893620B (en) | Chinese medicinal composition for preventing and treating diabetes and preparation method thereof | |
| CN102614260A (en) | Medicine for treating gastric ulcer and duodenal ulcer and preparing method and application thereof | |
| CN100333758C (en) | Gout resisting Chinese medicine composition and its prepn process | |
| CN105194460A (en) | Traditional Chinese medicine preparation for treating acute episode stage of wind-damp-heat type gout | |
| CN104491101B (en) | Preparing method of traditional Chinese medicine preparation for treatment of chronic renal failure | |
| CN103585580B (en) | A kind of Chinese medicine preparation for recurrent oral ulceration | |
| CN112755168A (en) | Traditional Chinese medicine preparation for treating chronic gastritis caused by helicobacter pylori and preparation method and application thereof | |
| CN101791386B (en) | Traditional Chinese veterinary medicine extract for promoting gastrointestinal peristalsis as well as preparation and preparation method thereof | |
| CN104940423A (en) | Traditional Chinese medicine preparation for treating gout | |
| CN109674854A (en) | A kind of shield pharynx treasure pill and preparation method thereof | |
| CN1327874C (en) | Chinese medicine formulation for treating chronic prostatitis and its preparing method | |
| CN104689137A (en) | Traditional Chinese medicine composition for treating acute icteric hepatitis | |
| CN104324201A (en) | Traditional Chinese medicine preparation for treating urinary system infection and production method | |
| CN1772073B (en) | Medicine composition for treating throat and oral cavity diseases and its preparation process | |
| CN109125631A (en) | Chinese medicine composition and preparation method thereof with liver kidney regulatory function | |
| CN106035915A (en) | Dried coptis deltoidea rhizome health-care tea for preventing diabetes and cardiovascular complications | |
| CN104491297B (en) | A kind of Chinese medicine composition for treating palindromic urinary tract infection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161116 |
|
| RJ01 | Rejection of invention patent application after publication |