CN106109535A - A kind of Lepidinm meyenii Walp ginseng and pilose antle health product of resisting fatigue - Google Patents
A kind of Lepidinm meyenii Walp ginseng and pilose antle health product of resisting fatigue Download PDFInfo
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- CN106109535A CN106109535A CN201610485602.XA CN201610485602A CN106109535A CN 106109535 A CN106109535 A CN 106109535A CN 201610485602 A CN201610485602 A CN 201610485602A CN 106109535 A CN106109535 A CN 106109535A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Abstract
The invention discloses the health product of a kind of resisting fatigue, it is made up of the raw material of following weight portion: pueraria root powder 200 220 parts, Radix Panacis Quinquefolii extract 20 40 parts, 40 50 parts of cervus elaphus linnaeus powder, Radix Rhodiolae extract 10 15 parts, 80 100 parts of dextrin.Health product raw material of the present invention is medicinal herb components, and raw material is natural, edible safety, and anti-fatigue effect is notable.Research shows that health product of the present invention have curative effect significantly to sports fatigue, and this health care product production process is simple, it is simple to take, action temperature and, be the health product of a kind of preferable resisting fatigue.
Description
Technical field
The present invention relates to a kind of health product, be specifically related to the Lepidinm meyenii Walp ginseng and pilose antle health product of the resisting fatigue of a kind of resisting fatigue.
Background technology
Lepidinm meyenii Walp is a kind of herbaceous plant originating in mountain area, Peru Andean, belongs to Cruciferae Lepidium, containing egg
The multiple nutritional components such as white matter, saccharide, lipid, aminoacid, fatty acid, mineral element, over the past thousands of years by local resident as food
With with medicinal high-quality resource.Research shows, Lepidinm meyenii Walp has raising fertility, resisting fatigue, improves sexual function, antioxidation, increasing
The multiple efficacies such as strong immunity, and without any side effects.
Radix Panacis Quinquefolii has boosting qi and nourishing yin, relieves inflammation or internal heat and promotes the production of body fluid, and clear away heart-fire the effect moisturized, and belongs to valuable medicinal, in can effectively strengthening
Pivot is neural, protects cardiovascular and cerebrovascular vessel, improves immunity, antitumor etc..
Cornu Cervi Pantotrichum is one of traditional valuable ingredient of Chinese medicine of China, can trace back to the history of Cornu Cervi Pantotrichum application many years ago the earliest, the successive dynasties
A lot of medical books the most all effects to Cornu Cervi Pantotrichum made to record, such as treatise on Febrile Diseases, " legendary god of farming's book on Chinese herbal medicine ", " herbal classic ", " not Lu ", " property of medicine
Opinion " etc., claim Cornu Cervi Pantotrichum sweet in the mouth, warm in nature, main leak down stagnant blood, cold and heat diarrhea induced by fright, the strong will of QI invigorating, the population does not waits for a long time.Cornu Cervi Pantotrichum can improve machine
The cellular immunization of body and humoral immune function, promote the conversion of lymphocyte, have the effect of immunopotentiating agent.It can increase machine
Body defence capability to external world, regulates internal immunologic balance and avoids disease to occur and promote wound healing, sick body rehabilitation, from
And play strengthening body, the effect of opposing aging.
Radix Rhodiolae is Crassulaceae rhodiola perennial herb or shrub plant, has meat, Fructus Vitis viniferae root stock.Have and people
Act on as ginseng, acanthopanax senticosus, and do not have be overexcited effect and the effect of Radix Et Caulis Acanthopanacis Senticosi cause constipation of Radix Ginseng, thus more
More attract widespread attention.
Fatigue is a kind of subjective uncomfortable sensation, but objectively under equal conditions can lose what it completed originally to be engaged in
Normal activity or ability to work.Resisting fatigue is through certain methods means to offset the sensation of this fatigue, so that people's sense
Feel light spiritedness.The reason that people are tired includes: excess eye-using, poor sleeping quality, at heart pressure are big, malnutrition, first shape
Glandular secretion is not enough.In modern society, people's rhythm of life is the fastest, it is easy to producing feeling of fatigue, therefore exploitation resisting fatigue is produced
Product are significant, and existing anti-fatigue product takes effect slowly, resisting fatigue weak effect and have side effect.
Summary of the invention
It is an object of the invention to provide the Lepidinm meyenii Walp ginseng and pilose antle health product of a kind of resisting fatigue.By Lepidinm meyenii Walp, Radix Panacis Quinquefolii, horse ginseng and pilose antler
Powder, Radix Rhodiolae extract are main Chinese crude drug, by mutual synergistic function, to improve the alleviating physical fatigue to body
Function.
The present invention is by the following technical solutions:
The Lepidinm meyenii Walp ginseng and pilose antle health product of a kind of resisting fatigue, it is characterised in that it is made up of the raw material of following weight portion: Lepidinm meyenii Walp
Powder 200-220 part, Radix Panacis Quinquefolii extract 20-40 part, cervus elaphus linnaeus powder 40-50 part, Radix Rhodiolae extract 10-15 part, dextrin 80-
100 parts.
Preferably, the Lepidinm meyenii Walp ginseng and pilose antle health product of described resisting fatigue are made up of the raw material of following weight portion: pueraria root powder 210
Part, Radix Panacis Quinquefolii extract 30 parts, 45 parts of cervus elaphus linnaeus powder, Radix Rhodiolae extract 13 parts, 90 parts of dextrin.
After described each raw material weighs according to quantity, conventionally make capsule, tablet, granule, powder or pill.
In instant component, Lepidinm meyenii Walp is warm in nature, sweet, flat.Return lung, kidney channel.To the cold limbs and aversion to cold caused because of insufficiency of kidney-YANG, spirit
Dispirited, depressed, menoxenia, the contracting of ovary flaccidity, men and women's sterility and infertility, impotence and premature ejaculation, libido decline have obvious dietetic therapy and
Health-care effect.Especially women is alleviated climacteric, slow down aging, the prostatic hyperplasia symptom such as male's frequent micturition, urgent micturition, urine puckery pain tool
There is well effect.Radix Panacis Quinquefolii is cool in nature, sweet in the mouth, micro-hardship, returns spleen, lung, the heart, kidney channel.It is applicable to the trouble of deficiency of both QI and YIN, disturbance of deficiency-heat inside the body
Person, has the effects such as benefiting qi and nourishing blood, enriching yin and nourishing kidney, strengthening the spleen and nourishing the stomach, slow down aging and skin care.Modern medicine study proves, the West
Ginseng has resisting fatigue, defying age, shock, raising thinking, improves memory and endocrine regulation, enhancing body immunity and improvement
Cardiovascular functioies etc. act on.Horse ginseng and pilose antler is warm in nature, bitter in the mouth, micro-sweet.Control severe disease, prolonged illness or massive hemorrhage collapse, weakness of the spleen and stomach, sexual function
Decline etc..There is the effects such as heart tonifying, calmness, blood sugar lowering, resisting fatigue, diuresis.Radix Rhodiolae is sweet, bitter in the mouth, flat.Return lung, heart channel.Tool
There is benefiting QI for activating blood circulation, effect relievingd asthma of promoting blood circulation.Radix Rhodiolae can improve sleep, blood-enriching and blood-promoting circulation, anti-cerebral anoxia, resisting fatigue, promoting blood circulation and hemostasis,
Clearing away lung-heat to relieve cough, change detumescence of becoming silted up, antipyretic bring down a fever, nourish the effects such as vigour；It is used for outward treating traumatic injury and burn and scald.
Inventor is found by development test, and the raw material components of health product of the present invention has significantly on the pathology of resisting fatigue
Synergistic function, reasonably combined by material composition ratio, each effective active component synergism can extend mice and climb
Bar and walking weight load, reduce the value of blood lactase acid serum lactate dehydrogenase (SLD) of mice after motion, increase mice liver glycogen and
Body development storage level, this shows that health product of the present invention contribute to body and maintain the normal function of health, delayed motion when motion
Tired generation, improves exercise tolerance, can significantly alleviate sports fatigue.
The invention has the beneficial effects as follows: health product raw material of the present invention is medicinal herb components, and raw material is natural, edible safety, anti-
Tired effect is notable.Clinical application research shows that health product of the present invention have curative effect significantly, and this health care to sports fatigue
Product production technology is simple, it is simple to take, action temperature and, be the health product of a kind of preferable resisting fatigue.
Detailed description of the invention
Below in conjunction with specifically embodiment, the present invention is described in further detail.
Embodiment 1
The Lepidinm meyenii Walp ginseng and pilose antle health product of a kind of resisting fatigue, it is made up of the raw material of following weight portion: pueraria root powder 200g, the West
Conopsea extraction 20g, cervus elaphus linnaeus powder 40g, Radix Rhodiolae extract 10g, dextrin 80g.
Above-mentioned raw materials composition employing conventional dose method is made tablet.
Embodiment 2
The Lepidinm meyenii Walp ginseng and pilose antle health product of a kind of resisting fatigue, it is made up of the raw material of following weight portion: pueraria root powder 220g, the West
Conopsea extraction 40g, cervus elaphus linnaeus powder 50g, Radix Rhodiolae extract 15g, dextrin 100g.
Above-mentioned raw materials composition employing conventional dose method is made capsule.
Embodiment 3
The Lepidinm meyenii Walp ginseng and pilose antle health product of a kind of resisting fatigue, it is made up of the raw material of following weight portion: pueraria root powder 210g, the West
Conopsea extraction 30g, cervus elaphus linnaeus powder 45g, Radix Rhodiolae extract 13g, dextrin 90g.
Above-mentioned raw materials composition employing conventional dose method is made powder.
Embodiment 4
The Lepidinm meyenii Walp ginseng and pilose antle health product of a kind of resisting fatigue, it is made up of the raw material of following weight portion: pueraria root powder 200g, the West
Conopsea extraction 35g, cervus elaphus linnaeus powder 48g, Radix Rhodiolae extract 12g, dextrin 95g.
Above-mentioned raw materials composition employing conventional dose method is made pill.
Anti-fatigue effect is tested
This experiment is designed with reference to " function of health food assessment process and the method for inspection ".
Experiment material
Laboratory animal: three monthly age kunming mices 70 (purchased from Hebei Medical University's biotic experiment center), body weight 18-22g.
Laboratory sample: the sample that embodiment 3 prepares.
Dosage choice and sample treatment: experiment sets blank group, matched group 1 (cervus elaphus linnaeus), matched group 2 (Radix Ginseng+red scape
My god+Lepidinm meyenii Walp), matched group 3 (prior art formula: Radix Ginseng+Radix Rhodiolae+Lepidinm meyenii Walp+Fructus Lycii+Herba Epimedii) and experimental group basic, normal, high by three
Individual dosage group, the most often organizes each 10.Each tested group of medicine is prepared as powder, then with the consumption of every mice 0.2ml every day
Be equipped to solution to mouse stomach with distilled water, experimental group each mice gavage every day (low dosage: 0.1mg/10g/day, middle dose
Amount: 0.53mg/10g/day, high dose: 5.3mg/10g/day, is respectively equivalent to 2 times of human body recommended amounts, 10 times, 100 times),
Matched group 1,2,3 be respectively adopted human body recommended dose 10 times are tested, and are carried out continuously 30 days, extend to 45 days if desired.
Key instrument and reagent: swimming trunk (size about 50cm × 50cm × 40cm), electronic balance, sheet lead；Diameter 1cm,
The Glass rod of long 25cm, after sand papering, upper end is fixed on plank and makes pole-climbing frame；Multi-functional microplate reader (synergy
Biotech), centrifuge (Thermo), Lactic acid Kit (100T/48 sample, Nanjing is built up), lactic dehydrogenase enzyme reagent kit (100T/
48 samples, Nanjing is built up), glycogen test kit (100T/48 sample, Nanjing is built up).
Experimental technique: by Loaned swimming test, pole-jump test, blood lactase acid determination experiment, measuring content of lactic dehydrogenase
Test, hepatic glycogen and muscle glycogen measure and carry out assessment of function.
Experimental result:
1, the product of the present invention impact on the mice burden swimming time.
The most direct tired and the most objectively performance is the decline of exercise tolerance, and swimming time is made all the time
For reflecting the important indicator of exercise tolerance.Concrete outcome is as shown in table 1.
Table 1 walking weight load experimental result
From data in table 1, mouse swimming power compared with blank group of gavage high, medium and low dosage group exhausts the time
Having increased, and the basic, normal, high dosage group increase time presents the trend gradually risen, this is from macroscopically embodying the present invention
Lepidinm meyenii Walp ginseng and pilose antle health product have good anti-fatigue ability.And compared with blank, compare 1 swimming time amplification less, and right
Comparing with blank group according to 2 and comparison 3, the swimming time of mice has extended, but after extending, swimming time is all not as this
The mice swimming time of bright 3 experimental grouies is long, and the present invention tests the swimming time amplification of middle and high dosage group than comparison 1 He
The summation of the time amplification compareing 2 groups also wants big, each component synergism of this explanation present invention, than single any component or
The simple combination effect appointing several components will be got well, and achieves unforeseeable effect, has the effect of significant resisting fatigue.
2, the product of the present invention impact on the mice pole-climbing time
The raising of exercise tolerance is that anti-fatigue ability strengthens the strongest macro manifestations, and the length of pole-climbing time can be reacted
Animal quiet firmly time tired degree.Concrete outcome is as shown in table 2.
Table 2 Grasping clubglass test result
As can be seen from Table 2, compared with blank group, basic, normal, high three dosage group pole-climbing times all rise appreciably,
Illustrate that Lepidinm meyenii Walp ginseng and pilose antle health product of the present invention have good antifatigue effect.Compare 1,2,3 groups compared with blank, all have certain
Antifatigue effect, but the product that its resisting fatigue effect does not all have the present invention is good, and this is the collaborative of each component due to the present invention
Effect is notable.
3, the product of the present invention impact on Mouse Blood lactic acid
Blood lactase acid is an important indicator of evaluation organism fatigue degree, and it is glucolytic product, to glycolysis energy supply
System is very sensitive.Under anaerobic environment, body still using glycogen as energy substance, except that, carbohydrate metabolism mistake now
Journey is anerobic glycolysis, and the energy that anerobic glycolysis not only produces is considerably less, and its product lactic acid is cause organism fatigue sense straight
Connect the factor, so by the lactic acid content of body after motion, we can judge that body is to the picked-up of oxygen and Utilization ability.
Table 3 blood lactase acid measurement result
| Group | Animal number of elements (only) | Blood lactase acid value (mmol/L) after motion |
| Experimental group low dosage | 10 | 4.45±0.3 |
| Dosage in experimental group | 10 | 4.76±0.5 |
| Experimental group high dose | 10 | 4.85±0.3 |
| Blank group | 10 | 5.77±0.36 |
| Matched group 1 | 10 | 5.66±0.9 |
| Matched group 2 | 10 | 5.31±0.8 |
| Matched group 3 | 10 | 5.05±0.8 |
As shown in Table 3, mice blank group blood lactase acid level after exercise is higher, is administered low dosage, middle dosage, high agent
Amount group mice blood lactase acid level compared with matched group significantly reduces, and this shows that Lepidinm meyenii Walp ginseng and pilose antle health product of the present invention can be by reducing
The generation of lactic acid in motion, reaches the effect of delay fatigue.Compare 1,2,3 groups of blood lactase acid levels and compare the most equal with blank group
Decrease, but overall reducing effect is good not as experimental group dose effect of the present invention.
4, the product of the present invention impact on mice serum lactic acid dehydrogenase
Table 4 measuring content of lactic dehydrogenase result
Lactic acid dehydrogenase is a kind of glycolytic ferment, and it can be catalyzed acetone acid and generate lactic acid, be almost present in a organized way in.
Can be drawn by table 4, after mice swimming exercise, be administered basic, normal, high dosage group lactic acid dehydrogenase and all decrease, and in
Dosage has bigger reduction with high dose group compared with matched group, and this shows that Lepidinm meyenii Walp ginseng and pilose antle health product of the present invention can reduce breast
The content of acidohydrogenase, thus reduce the generation of lactic acid, reach the effect of resisting fatigue.
5, product of the present invention is on Mouse Liver glycogen and the impact of Body development storage level
Liver glycogen and Body development provide preferable energy reserves at the volley for body, measure animal body liver glycogen and flesh
Stocking of glycogen, it is possible to as the sensitive indicator of reflection degree of fatigue.
Table 5 hepatic glycogen and muscle glycogen content measurement result
| Group | Animal number of elements (only) | Hepatic glycogen content (mg/g) | Muscle glycogen content (mg/g) |
| Experimental group low dosage | 10 | 2.43±0.21 | 0.282±0.02 |
| Dosage in experimental group | 10 | 6.12±0.23 | 0.293±0.03 |
| Experimental group high dose | 10 | 6.54±0.68 | 0.392±0.05 |
| Blank group | 10 | 2.15±0.18 | 0.271±0.05 |
| Matched group 1 | 10 | 2.69±0.13 | 0.279±0.04 |
| Matched group 2 | 10 | 3.45±0.42 | 0.281±0.03 |
| Matched group 3 | 10 | 5.28±0.51 | 0.318±0.05 |
Be can be seen that by table 5, after mice swimming exercise, be administered basic, normal, high dosage group liver glycogen and raised, its
In, middle dosage group, high dose group hepatic glycogen content compared with matched group improve a lot.It is administered basic, normal, high dosage group quantitatively
After swimming, Body development content has raised, and high dose group muscle glycogen content compared with matched group has more significant raising,
This shows that the Lepidinm meyenii Walp ginseng and pilose antle health product of the present invention can significantly improve the reserve capabillity of body liver glycogen Body development, thus carries for body
The purpose of resisting fatigue is reached for more energy.Although and compareing the hepatic glycogen of 1,2,3 groups and muscle glycogen content has necessarily
Raising, but its effect and result of the present invention have bigger gap.
In sum, the product of the present invention can extend mice pole-climbing and walking weight load, reduces the blood of mice after moving
Lactic acid and the value of serum lactate dehydrogenase (SLD), increase liver glycogen and the Body development storage level of mice, shows that it contributes to body in fortune
Maintain the normal function of health, the generation that delayed motion is tired time dynamic, improve exercise tolerance, i.e. can well alleviate mobility
Fatigue, reaches the health-care effect of resisting fatigue.
Claims (3)
1. the Lepidinm meyenii Walp ginseng and pilose antle health product of a resisting fatigue, it is characterised in that it is made up of the raw material of following weight portion: pueraria root powder
200-220 part, Radix Panacis Quinquefolii extract 20-40 part, cervus elaphus linnaeus powder 40-50 part, Radix Rhodiolae extract 10-15 part, dextrin 80-100
Part.
The Lepidinm meyenii Walp ginseng and pilose antle health product of resisting fatigue the most according to claim 1, it is characterised in that it is by following weight portion
Raw material forms: pueraria root powder 210 parts, Radix Panacis Quinquefolii extract 30 parts, 45 parts of cervus elaphus linnaeus powder, Radix Rhodiolae extract 13 parts, 90 parts of dextrin.
The Lepidinm meyenii Walp ginseng and pilose antle health product of resisting fatigue the most according to claim 1, it is characterised in that described each raw material weighs according to quantity
After, conventionally make capsule, tablet, granule, powder or pill.
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| CN113785982A (en) * | 2021-11-15 | 2021-12-14 | 北京笑傲天宫生物科技有限公司 | Anti-fatigue and anti-radiation capsule for spaceflight and preparation method thereof |
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