CN106103733A - 药效评价方法以及用于药效评价的图像处理装置 - Google Patents

药效评价方法以及用于药效评价的图像处理装置 Download PDF

Info

Publication number
CN106103733A
CN106103733A CN201480077258.XA CN201480077258A CN106103733A CN 106103733 A CN106103733 A CN 106103733A CN 201480077258 A CN201480077258 A CN 201480077258A CN 106103733 A CN106103733 A CN 106103733A
Authority
CN
China
Prior art keywords
drug effect
image
glomeration
cell
spheroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480077258.XA
Other languages
English (en)
Chinese (zh)
Inventor
藤本博己
小林正嘉
佐佐木隆造
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Screen Holdings Co Ltd
Original Assignee
Screen Holdings Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Screen Holdings Co Ltd filed Critical Screen Holdings Co Ltd
Publication of CN106103733A publication Critical patent/CN106103733A/zh
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/002D [Two Dimensional] image generation
    • G06T11/003Reconstruction from projections, e.g. tomography
    • G06T11/006Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/62Analysis of geometric attributes of area, perimeter, diameter or volume
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N13/00Stereoscopic video systems; Multi-view video systems; Details thereof
    • H04N13/20Image signal generators
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10101Optical tomography; Optical coherence tomography [OCT]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N13/00Stereoscopic video systems; Multi-view video systems; Details thereof
    • H04N13/10Processing, recording or transmission of stereoscopic or multi-view image signals
    • H04N13/106Processing image signals
    • H04N13/111Transformation of image signals corresponding to virtual viewpoints, e.g. spatial image interpolation

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Geometry (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Signal Processing (AREA)
  • Multimedia (AREA)
  • Algebra (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Mathematical Analysis (AREA)
CN201480077258.XA 2014-03-20 2014-11-18 药效评价方法以及用于药效评价的图像处理装置 Pending CN106103733A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014057594A JP6325858B2 (ja) 2014-03-20 2014-03-20 薬効評価方法および画像処理装置
JP2014-057594 2014-03-20
PCT/JP2014/080438 WO2015141059A1 (ja) 2014-03-20 2014-11-18 薬効評価方法および薬効評価のための画像処理装置

Publications (1)

Publication Number Publication Date
CN106103733A true CN106103733A (zh) 2016-11-09

Family

ID=54144055

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480077258.XA Pending CN106103733A (zh) 2014-03-20 2014-11-18 药效评价方法以及用于药效评价的图像处理装置

Country Status (6)

Country Link
US (1) US20160349240A1 (ko)
EP (1) EP3121287B1 (ko)
JP (1) JP6325858B2 (ko)
KR (1) KR101871082B1 (ko)
CN (1) CN106103733A (ko)
WO (1) WO2015141059A1 (ko)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110022863A (zh) * 2017-01-10 2019-07-16 株式会社斯库林集团 粒状物、读取装置及印刷装置
CN113720823A (zh) * 2021-05-17 2021-11-30 丹望医疗科技(上海)有限公司 检测类器官最大截面积的方法及其应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6122817B2 (ja) * 2014-03-26 2017-04-26 株式会社Screenホールディングス スフェロイドの評価方法およびスフェロイド評価装置
JP2017055864A (ja) * 2015-09-15 2017-03-23 京楽産業.株式会社 遊技機
CN109196112B (zh) * 2016-06-16 2022-10-04 株式会社日立高新技术 球状体内部细胞状态的分析方法
JP6864313B2 (ja) * 2016-12-20 2021-04-28 株式会社Screenホールディングス 化学物質の評価方法
JP6722620B2 (ja) * 2017-06-09 2020-07-15 株式会社日立ハイテク 細胞状態の解析装置および解析方法
JP6971758B2 (ja) * 2017-10-10 2021-11-24 オリンパス株式会社 観察システム
JP7107528B2 (ja) * 2018-12-20 2022-07-27 株式会社Screenホールディングス 細胞培養容器

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011062166A (ja) * 2009-09-18 2011-03-31 National Institute Of Advanced Industrial Science & Technology 薬剤が細胞に与える影響を評価するシステム
US20130295578A1 (en) * 2011-01-10 2013-11-07 Trustees Of Dartmouth College Methods for screening for drug resistance in cancer treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002303150A1 (en) * 2001-03-26 2002-10-08 Cellomics, Inc. Methods for determining the organization of a cellular component of interest
JP5293733B2 (ja) * 2008-02-28 2013-09-18 株式会社ニコン 顕微鏡装置および細胞培養装置
JP2012202761A (ja) * 2011-03-24 2012-10-22 Nikon Corp 光干渉断層撮影装置
JP5955163B2 (ja) * 2011-09-06 2016-07-20 キヤノン株式会社 画像処理装置および画像処理方法
WO2013039112A1 (ja) * 2011-09-12 2013-03-21 国立大学法人九州大学 二次元培養細胞を三次元培養又は生体内と同様に活性化する方法及びその利用
JP5748281B2 (ja) * 2011-09-21 2015-07-15 株式会社トプコン 光干渉断層画像処理方法及びその装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011062166A (ja) * 2009-09-18 2011-03-31 National Institute Of Advanced Industrial Science & Technology 薬剤が細胞に与える影響を評価するシステム
US20130295578A1 (en) * 2011-01-10 2013-11-07 Trustees Of Dartmouth College Methods for screening for drug resistance in cancer treatment

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SAVAGE A等: "Characterising the tumour morphological response to therapeutic intervention:an ex vivo model", 《DISEASE MODELS & MECHANISMS》 *
SHARMA M等: "Imaging growth dynamics of tumour spheroids using optical coherence tomography", 《BIOTECHNOL LETT.》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110022863A (zh) * 2017-01-10 2019-07-16 株式会社斯库林集团 粒状物、读取装置及印刷装置
CN113720823A (zh) * 2021-05-17 2021-11-30 丹望医疗科技(上海)有限公司 检测类器官最大截面积的方法及其应用
WO2022241929A1 (zh) * 2021-05-17 2022-11-24 丹望医疗科技(上海)有限公司 检测类器官最大截面积的方法及其应用

Also Published As

Publication number Publication date
KR20160084429A (ko) 2016-07-13
US20160349240A1 (en) 2016-12-01
EP3121287A4 (en) 2018-01-03
JP2015181348A (ja) 2015-10-22
EP3121287B1 (en) 2024-06-12
EP3121287A1 (en) 2017-01-25
WO2015141059A1 (ja) 2015-09-24
JP6325858B2 (ja) 2018-05-16
KR101871082B1 (ko) 2018-06-25

Similar Documents

Publication Publication Date Title
CN106103733A (zh) 药效评价方法以及用于药效评价的图像处理装置
Paulus Measuring crops in 3D: using geometry for plant phenotyping
Sun et al. In-field high-throughput phenotyping of cotton plant height using LiDAR
Hobart et al. Growth height determination of tree walls for precise monitoring in apple fruit production using UAV photogrammetry
Moskal et al. Retrieving forest inventory variables with terrestrial laser scanning (TLS) in urban heterogeneous forest
CN102033314B (zh) 影像采集装置和影像显示方法
Martinez-Guanter et al. Low-cost three-dimensional modeling of crop plants
Sun et al. Three-dimensional point cloud reconstruction and morphology measurement method for greenhouse plants based on the kinect sensor self-calibration
CN109154563B (zh) 用于获取样本中所存在的粒子的装置和方法
Méndez et al. In-field estimation of orange number and size by 3D laser scanning
CN105547152A (zh) 农作物表型田间高通量主动测量装置与方法
Ramirez et al. Testing the application of terrestrial laser scanning to measure forest canopy gap fraction
Debnath et al. Applications of LiDAR in agriculture and future research directions
Li et al. Impact of camera viewing angle for estimating leaf parameters of wheat plants from 3D point clouds
Gierwiało et al. Medical augmented-reality visualizer for surgical training and education in medicine
Zhao et al. A high throughput integrated hyperspectral imaging and 3D measurement system
CN113198692A (zh) 一种适用于批量产品的高精度点胶方法及装置
Azizi et al. Estimation of soil surface roughness using stereo vision approach
Hu et al. Assessing the self-recovery ability of maize after lodging using UAV-LiDAR data
Kot et al. Using virtual scanning to find optimal configuration of a 3D scanner turntable for scanning of mechanical parts
Lati et al. 3-D image-driven morphological crop analysis: a novel method for detection of sunflower broomrape initial subsoil parasitism
Esser et al. Quality analysis of a high-precision kinematic laser scanning system for the use of spatio-temporal plant and organ-level phenotyping in the field
CN103852031B (zh) 一种电子设备及测量物体形状的方法
Zaji et al. Wheat spikes height estimation using stereo cameras
Žabota et al. The Potential of UAV-Acquired Photogrammetric and LiDAR-Point Clouds for Obtaining Rock Dimensions as Input Parameters for Modeling Rockfall Runout Zones

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20161109