CN106102741A - 包含抗菌剂的药物组合物 - Google Patents

包含抗菌剂的药物组合物 Download PDF

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Publication number
CN106102741A
CN106102741A CN201480069915.6A CN201480069915A CN106102741A CN 106102741 A CN106102741 A CN 106102741A CN 201480069915 A CN201480069915 A CN 201480069915A CN 106102741 A CN106102741 A CN 106102741A
Authority
CN
China
Prior art keywords
pharmaceutically acceptable
acceptable derivative
compound
formula
cefepime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480069915.6A
Other languages
English (en)
Chinese (zh)
Inventor
萨欣·巴格瓦
维特哈伯海·帕特 马哈斯
马哈斯维特哈伯海·帕特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Ltd
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Priority to CN202110966872.3A priority Critical patent/CN113577084A/zh
Publication of CN106102741A publication Critical patent/CN106102741A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
CN201480069915.6A 2013-10-22 2014-10-22 包含抗菌剂的药物组合物 Pending CN106102741A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110966872.3A CN113577084A (zh) 2013-10-22 2014-10-22 包含抗菌剂的药物组合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3309/MUM/2013 2013-10-22
PCT/IB2014/065522 WO2015059643A1 (en) 2013-10-22 2014-10-22 Pharmaceutical compositions comprising antibacterial agents
IN3309MU2013 IN2013MU03309A (enExample) 2013-10-22 2014-10-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202110966872.3A Division CN113577084A (zh) 2013-10-22 2014-10-22 包含抗菌剂的药物组合物

Publications (1)

Publication Number Publication Date
CN106102741A true CN106102741A (zh) 2016-11-09

Family

ID=52003012

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480069915.6A Pending CN106102741A (zh) 2013-10-22 2014-10-22 包含抗菌剂的药物组合物
CN202110966872.3A Pending CN113577084A (zh) 2013-10-22 2014-10-22 包含抗菌剂的药物组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202110966872.3A Pending CN113577084A (zh) 2013-10-22 2014-10-22 包含抗菌剂的药物组合物

Country Status (18)

Country Link
US (1) US9827235B2 (enExample)
EP (1) EP3060213B1 (enExample)
JP (2) JP2016538258A (enExample)
KR (1) KR102340010B1 (enExample)
CN (2) CN106102741A (enExample)
AU (1) AU2014338612C1 (enExample)
BR (1) BR112016008979B1 (enExample)
CA (1) CA2928364C (enExample)
DK (1) DK3060213T3 (enExample)
ES (1) ES2902456T3 (enExample)
HU (1) HUE057504T2 (enExample)
IN (1) IN2013MU03309A (enExample)
MX (1) MX375934B (enExample)
NZ (1) NZ719215A (enExample)
PL (1) PL3060213T3 (enExample)
PT (1) PT3060213T (enExample)
RU (1) RU2702361C2 (enExample)
WO (1) WO2015059643A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107580595B (zh) * 2015-05-07 2020-09-18 拜欧蒂姆公司 杂环化合物及它们在预防或治疗细菌感染中的应用
CN109310682A (zh) * 2016-06-17 2019-02-05 沃克哈特有限公司 抗菌组合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013030733A1 (en) * 2011-08-27 2013-03-07 Wockhardt Limited 1,6- diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections
US20130225554A1 (en) * 2011-12-02 2013-08-29 Naeja Pharmaceutical Inc. New bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465428B1 (en) * 1999-08-27 2002-10-15 Aventis Pharma S.A. Pharmaceutical combinations based on dalfopristine and quinupristine, and on cefepime
MX2007007235A (es) * 2004-12-17 2007-10-19 Venus Remedies Ltd Combinacion de antibioticos para proporcionar una solucion total al tratamiento de infecciones.
RU2366450C1 (ru) * 2008-08-04 2009-09-10 Валентина Васильевна Малиновская Средство для лечения тяжелых инфекционных заболеваний и смешанных инфекций
CA2842777C (en) * 2011-07-26 2015-12-29 Wockhardt Limited Pharmaceutical compositions comprising sulbactam and beta-lactamase inhibitor
HUE046893T2 (hu) * 2012-05-30 2020-04-28 Meiji Seika Pharma Co Ltd Új ß-laktamáz inhibitor és eljárás elõállítására
AU2014206087A1 (en) * 2013-01-14 2015-05-28 Wockhardt Limited Compositions and methods for treating bacterial infections

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013030733A1 (en) * 2011-08-27 2013-03-07 Wockhardt Limited 1,6- diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections
US20130225554A1 (en) * 2011-12-02 2013-08-29 Naeja Pharmaceutical Inc. New bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors

Also Published As

Publication number Publication date
CN113577084A (zh) 2021-11-02
IN2013MU03309A (enExample) 2015-07-17
AU2014338612B2 (en) 2019-12-19
PL3060213T3 (pl) 2022-02-14
US20160303104A1 (en) 2016-10-20
KR20160072254A (ko) 2016-06-22
DK3060213T3 (da) 2022-01-03
WO2015059643A1 (en) 2015-04-30
RU2016115376A (ru) 2017-11-28
NZ719215A (en) 2020-04-24
KR102340010B1 (ko) 2021-12-16
PT3060213T (pt) 2021-12-24
CA2928364A1 (en) 2015-04-30
MX375934B (es) 2025-03-07
ES2902456T3 (es) 2022-03-28
RU2702361C2 (ru) 2019-10-08
CA2928364C (en) 2021-11-23
AU2014338612C1 (en) 2020-09-24
RU2016115376A3 (enExample) 2018-07-02
US9827235B2 (en) 2017-11-28
JP2019116508A (ja) 2019-07-18
HUE057504T2 (hu) 2022-05-28
BR112016008979A2 (enExample) 2017-08-01
MX2016005161A (es) 2016-10-05
EP3060213A1 (en) 2016-08-31
JP2016538258A (ja) 2016-12-08
BR112016008979B1 (pt) 2023-04-25
EP3060213B1 (en) 2021-10-13
JP6886996B2 (ja) 2021-06-16

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Legal Events

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20161109

RJ01 Rejection of invention patent application after publication