CN106038345A - Mask containing gamma-aminobutyric acid - Google Patents
Mask containing gamma-aminobutyric acid Download PDFInfo
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- CN106038345A CN106038345A CN201610391413.6A CN201610391413A CN106038345A CN 106038345 A CN106038345 A CN 106038345A CN 201610391413 A CN201610391413 A CN 201610391413A CN 106038345 A CN106038345 A CN 106038345A
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- gamma
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- aminobutyric acid
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- aminoacid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
A mask containing gamma-aminobutyric acid is characterized by being prepared from components in percentage by weight as follows: 1.50% of gamma-aminobutyric acid, 10.25% of glycerin, 12.60% of betaine, 8.95% of hydrolyzed starch, 2.50% of sodium hyaluronate and 15.60% of a purslane extract. The mask has the benefits as follows: gamma-aminobutyric acid contained in the mask containing gamma-aminobutyric acid is a main inhibiting neurotransmitter for a central nervous system and can prevent skin from ageing; more importantly, gamma-aminobutyric acid can increase the permeability of a cell body membrane, hyperpolarization is formed, absorption of nutritional substances is better facilitated, various natural ingredients containing rich amino acid are injected into the deep layer of skin for concentrated whitening, and loose and dry skin without gloss become glossy and active skin. The content of heavy metal mercury is low, no toxic or side effects are caused, and the mask can be used safely for a long time.
Description
Technical field
The invention belongs to cosmetic technical field, a kind of facial film containing gamma-aminobutyric acid.
Background technology
γ-aminobutyric acid, English name: γ-aminobutyric acid (GABA), chemical name: 4-Aminobutanoicacid
, another name: γ-aminobutyric acid, aminobutyric acid, nipecotic acid.Molecular formula: C4H9NO2.Molecular weight: 103.1.It is distributed widely in dynamic planting
In object.Seed, rhizome and the tissue fluid of plant such as Macroptilium, ginseng genus, Chinese herbal medicine etc. all contains GABA.In animal body,
GABA almost exists only in nervous tissue, and the content in its mesencephalic tissue is about 0.1-0.6mg/ gram of tissue, and immunology is ground
Studying carefully and show, the region that its concentration is the highest is black substance in brain.GABA is to study the most deep a kind of important inhibition at present
Neurotransmitter, it participates in multiple metabolic activity, has the highest physiologically active, has neurotransmission, improves brain function, enhancing note
Recall, anxiety, treatment epilepsy, Control of asthma, regulation hormone secretion, prevent obesity, promote reproduction, activation Liver and kidney, improve nerve
Cellularity senile dementia, alleviate cerebral thrombosis, alleviate cerebral arteriosclerosis cause headache, alleviate the physiological functions such as tinnitus, extensively should
For fields such as food, medicine, cosmetics and feedstuffs.
The patent of invention of China's Patent No. 201510943689.6 discloses a kind of containing γ-aminobutyric acid and hyalomitome
The compositions of acid and the application in cosmetics thereof, can conduct by calm nerves, lax histrionic muscles, wrinkle reduction, hyaluronic acid energy
Penetrate into skin, fill rapidly, thus play the effect reducing wrinkle, through short-term and long-term wrinkle removal experimental verification, this compositions energy
Quickly wrinkle removal, long-acting moisturizing, make skin rejuvenation, overcome prior art wrinkle reduction defect slowly.Patent No.
The patent of invention of 200810159366.8 discloses a kind of γ-gamma-aminobutyric acid toner, has and prevents pigmentation, prevents color
Effect of speckle.Preferably solve skin and there are some problems.
But the cosmetics nutrition of prior art is single, and nutrition is unfavorable for skin absorption, weighs more or less
Tenor is higher, and particularly mercury content is higher, has toxic and side effects, brings potential safety hazard to consumer.
Summary of the invention
It is an object of the invention to provide a kind of facial film containing gamma-aminobutyric acid, not only nutrition more comprehensive and abundant, and
Its nutrition is advantageously in skin absorption, and heavy metal Hg content is relatively low, has no side effect, can safe life-time service.
For solving above-mentioned technical problem, the technical solution adopted in the present invention is: a kind of facial film containing gamma-aminobutyric acid,
The each composition and the percentage by weight that it is characterized in that the described facial film containing gamma-aminobutyric acid be: gamma amino acid/11 .50%, sweet
Oil 10.25%, glycine betaine 12.60%, hydrolysis starch 8.95%, hyaluronate sodium 2.50%, Herba portulacae extract 15.60%, glycyrrhizic acid
Potassium 3.50%, aminoacid 25.50%, butanediol 5.50%, ethyl hexyl ester 3.15%, fragrance 0.03%, pure water 10.92%.
Described gamma aminoacid, uses fermented by lactic acid bacteria to produce, through the catalytic action of glutamic acid decarboxylase organized enzyme, makes paddy
Propylhomoserin decarboxylation is gamma-aminobutyric acid, and the least concentration of glutamic acid is 10mmoL/L, produce gamma-aminobutyric acid without any miscellaneous bacteria,
Reach food sanitation standard, use safety.
Described glycine betaine, for the alkaloid extracted from Radix Betae, not only has a good cleaning action, and bactericidal antiphlogistic,
The most do not injure skin, use safety.
Described Herba portulacae extracting solution, is that the biology that has using extraction the low temperature method stem from Herba Portulacae and leaf to obtain is lived
Property flavone and the mixture of Saponin, have the most anti-drying aging, increase skin comfort degree and remove free radical, improve
The combination property of skin comfort.
Described dipotaccium glycyrrhizate, for the glycyrrhizic acid list potassium extracted from Radix Glycyrrhizae, glycyrrhizic acid dipotassium, the mixing of tripotassium glycyrrhetate
Thing, has low thermal performance, frothing capacity, has antiinflammatory, antioxygen, antibacterial, treatment wound, effectively removing superoxide ion and hydroxyl free
Base, significantly inhibit the effect of liposome peroxidation thing.
Described aminoacid, use lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid,
In proline, glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, cysteine
A kind of or a kind of with mixture.
Each composition of said ratio is put into and mulser is sufficiently stirred for 6 hours, obtain facial mask liquid, then refer to
Mark detection, qualified after, facial mask liquid utilizes automatic filling machine insert in the facial film of vacuum defoamation, packs.
The invention has the beneficial effects as follows: be central nervous system containing the gamma-aminobutyric acid contained by gamma-aminobutyric acid facial film
Unite main suppression neurotransmitter, nerve can be loosened for cosmetics, reduce wrinkle, play cosmetic result, it is also possible to prevent skin
Skin is aging, it is often more important that gamma-aminobutyric acid can make the permeability of cyton film increase, and produces hyperpolarization, advantageously in battalion
Support the absorption of material, make to inject deep skin rich in amino acid whose various natural components and concentrate whitening, losing skin gloss, dredging
Pine, the skin being dried change the skin of brilliance and vigor into；Heavy metal Hg content of the present invention is relatively low, has no side effect, can be the longest
Phase uses.
Detailed description of the invention:
Further illustrate the present invention below in conjunction with embodiment, but embodiment is only that the explanation present invention rather than carries out it
Limit.
Embodiment 1:
Prepare 1000 grams of facial films containing gamma-aminobutyric acid, weigh gamma amino acid/11 5.00 grams, glycerol 102.50 grams, sweet respectively
126.00 grams of dish alkali, hydrolysis starch 89.50 grams, hyaluronate sodium 25.00 grams, Herba portulacae extract 156.00 grams, dipotaccium glycyrrhizate
35.00 grams, 255.00 grams of aminoacid, butanediol 55.00 grams, ethyl hexyl ester 31.50 grams, fragrance 0.30 gram, pure water
109.20 gram.Then each composition of above-mentioned weight is sequentially placed in mulser and is sufficiently stirred for 6 hours, obtain facial mask liquid,
Then carry out Indexs measure, qualified after, in the facial film after facial mask liquid utilizes automatic filling machine insert vacuum defoamation, packaging is i.e.
Can.
Described gamma aminoacid, uses fermented by lactic acid bacteria to produce, through the catalytic action of glutamic acid decarboxylase organized enzyme, makes paddy
Propylhomoserin decarboxylation is gamma-aminobutyric acid, and the least concentration of glutamic acid is 10mmoL/L, produce gamma-aminobutyric acid without any miscellaneous bacteria,
Reach food sanitation standard, use safety.
Described glycine betaine, for the alkaloid extracted from Radix Betae, not only has a good cleaning action, and bactericidal antiphlogistic,
The most do not injure skin, use safety.
Described Herba portulacae extracting solution, is that the biology that has using extraction the low temperature method stem from Herba Portulacae and leaf to obtain is lived
Property flavone and the mixture of Saponin, have the most anti-drying aging, increase skin comfort degree and remove free radical, improve
The combination property of skin comfort.
Described dipotaccium glycyrrhizate, for from Radix Glycyrrhizae extract glycyrrhizic acid list potassium, there is low thermal performance, frothing capacity, have antiinflammatory,
Antioxygen, antibacterial, treatment wound, effectively remove superoxide ion and hydroxyl radical free radical, significantly inhibit the effect of liposome peroxidation thing.
Described aminoacid, use lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid,
The mixture of proline.
Heavy metal Hg detects:
Take facial mask liquid 5g containing gamma-aminobutyric acid in reaction bulb, add 20ml distilled water and shake up, after 5 minutes, add
0.2g tartaric acid, then shake up, take inspection hydrargyrum Guan Yizhi, fill in reagent in lower end cotton a little, insert 1/2 and survey hydrargyrum reagent paper, at inspection hydrargyrum
It is cotton that pipe upper end fills in a little reagent again, is inserted in plug with holes the lower end of inspection hydrargyrum pipe, adds a piece of aerogenesis in reaction bulb
Sheet, immediately by the plug insertion reaction bottleneck with inspection hydrargyrum pipe, treats that aerogenesis stops, and observes hydrargyrum reagent paper situation of change, finds examination
Paper does not has variable color to be negative, and result concludes that the high-load of its hydrargyrum is 0.1 mg/Kg.
Embodiment 2:
Prepare 2000 grams of facial films containing gamma-aminobutyric acid, weigh 30.00 grams of gamma aminoacid, glycerol 205.00 grams, sweet respectively
252.00 grams of dish alkali, hydrolysis starch 179.00 grams, hyaluronate sodium 50.00 grams, Herba portulacae extract 312.00 grams, dipotaccium glycyrrhizate
70.00 grams, 510.00 grams of aminoacid, butanediol 110.00 grams, ethyl hexyl ester 63.00 grams, fragrance 0.60 gram, pure water
218.40 gram.Then each composition of above-mentioned weight is sequentially placed in mulser and is sufficiently stirred for 6 hours, obtain facial mask liquid,
Then carry out Indexs measure, qualified after, in the facial film after facial mask liquid utilizes automatic filling machine insert vacuum defoamation, packaging is i.e.
Can.
Described gamma aminoacid, uses fermented by lactic acid bacteria to produce, through the catalytic action of glutamic acid decarboxylase organized enzyme, makes paddy
Propylhomoserin decarboxylation is gamma-aminobutyric acid, and the least concentration of glutamic acid is 10mmoL/L, produce gamma-aminobutyric acid without any miscellaneous bacteria,
Reach food sanitation standard, use safety.
Described glycine betaine, for the alkaloid extracted from Radix Betae, not only has a good cleaning action, and bactericidal antiphlogistic,
The most do not injure skin, use safety.
Described Herba portulacae extracting solution, is that the biology that has using extraction the low temperature method stem from Herba Portulacae and leaf to obtain is lived
Property flavone and the mixture of Saponin, have the most anti-drying aging, increase skin comfort degree and remove free radical, improve
The combination property of skin comfort.
Described dipotaccium glycyrrhizate, for from Radix Glycyrrhizae extract glycyrrhizic acid dipotassium, there is low thermal performance, frothing capacity, have antiinflammatory,
Antioxygen, antibacterial, treatment wound, effectively remove superoxide ion and hydroxyl radical free radical, significantly inhibit the effect of liposome peroxidation thing.
Described aminoacid, uses glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, benzene
Alanine, the mixture of cysteine.
Heavy metal Hg detects:
Take facial mask liquid 5g containing gamma-aminobutyric acid in reaction bulb, add 20ml distilled water and shake up, after 5 minutes, add
0.2g tartaric acid, then shake up, take inspection hydrargyrum Guan Yizhi, fill in reagent in lower end cotton a little, insert 1/2 and survey hydrargyrum reagent paper, at inspection hydrargyrum
It is cotton that pipe upper end fills in a little reagent again, is inserted in plug with holes the lower end of inspection hydrargyrum pipe, adds a piece of aerogenesis in reaction bulb
Sheet, immediately by the plug insertion reaction bottleneck with inspection hydrargyrum pipe, treats that aerogenesis stops, and observes hydrargyrum reagent paper situation of change, finds examination
Paper does not has variable color to be negative, and result concludes that the high-load of its hydrargyrum is 0.1 mg/Kg.
Embodiment 3:
Prepare 2000 grams of facial films containing gamma-aminobutyric acid, weigh 30.00 grams of gamma aminoacid, glycerol 205.00 grams, sweet respectively
252.00 grams of dish alkali, hydrolysis starch 179.00 grams, hyaluronate sodium 50.00 grams, Herba portulacae extract 312.00 grams, dipotaccium glycyrrhizate
70.00 grams, 510.00 grams of aminoacid, butanediol 110.00 grams, ethyl hexyl ester 63.00 grams, fragrance 0.60 gram, pure water
218.40 gram.Then each composition of above-mentioned weight is sequentially placed in mulser and is sufficiently stirred for 6 hours, obtain facial mask liquid,
Then carry out Indexs measure, qualified after, in the facial film after facial mask liquid utilizes automatic filling machine insert vacuum defoamation, packaging is i.e.
Can.
Described gamma aminoacid, uses fermented by lactic acid bacteria to produce, through the catalytic action of glutamic acid decarboxylase organized enzyme, makes paddy
Propylhomoserin decarboxylation is gamma-aminobutyric acid, and the least concentration of glutamic acid is 10mmoL/L, produce gamma-aminobutyric acid without any miscellaneous bacteria,
Reach food sanitation standard, use safety.
Described glycine betaine, for the alkaloid extracted from Radix Betae, not only has a good cleaning action, and bactericidal antiphlogistic,
The most do not injure skin, use safety.
Described Herba portulacae extracting solution, is that the biology that has using extraction the low temperature method stem from Herba Portulacae and leaf to obtain is lived
Property flavone and the mixture of Saponin, have the most anti-drying aging, increase skin comfort degree and remove free radical, improve
The combination property of skin comfort.
Described dipotaccium glycyrrhizate, for from Radix Glycyrrhizae extract tripotassium glycyrrhetate, there is low thermal performance, frothing capacity, have antiinflammatory,
Antioxygen, antibacterial, treatment wound, effectively remove superoxide ion and hydroxyl radical free radical, significantly inhibit the effect of liposome peroxidation thing.
Described aminoacid, use lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid,
Proline, glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, cysteine
Mixture.
Heavy metal Hg detects:
Take facial mask liquid 5g containing gamma-aminobutyric acid in reaction bulb, add 20ml distilled water and shake up, after 5 minutes, add
0.2g tartaric acid, then shake up, take inspection hydrargyrum Guan Yizhi, fill in reagent in lower end cotton a little, insert 1/2 and survey hydrargyrum reagent paper, at inspection hydrargyrum
It is cotton that pipe upper end fills in a little reagent again, is inserted in plug with holes the lower end of inspection hydrargyrum pipe, adds a piece of aerogenesis in reaction bulb
Sheet, immediately by the plug insertion reaction bottleneck with inspection hydrargyrum pipe, treats that aerogenesis stops, and observes hydrargyrum reagent paper situation of change, finds examination
Paper does not has variable color to be negative, and result concludes that the high-load of its hydrargyrum is 0.1 mg/Kg.
Detecting the sample in above three embodiment respectively, testing result is as follows:
1,3.5≤PH(25 DEG C) >=8.5；
2, total plate count≤1000CFU/g;
3, yeast and mold sum≤100CFU/g；
4, lead≤4.0mg/kg；
5, hydrargyrum≤0.1mg/kg；
6, arsenic≤1.0mg/kg；
7, methanol≤200mg/kg.
The invention has the beneficial effects as follows: be central nervous system containing the gamma-aminobutyric acid contained by gamma-aminobutyric acid facial film
Unite main suppression neurotransmitter, nerve can be loosened for cosmetics, reduce wrinkle, play cosmetic result, it is also possible to prevent skin
Skin is aging, it is often more important that gamma-aminobutyric acid can make the permeability of cyton film increase, and produces hyperpolarization, advantageously in battalion
Support the absorption of material, make to inject deep skin rich in amino acid whose various natural components and concentrate whitening, losing skin gloss, dredging
Pine, the skin being dried change the skin of brilliance and vigor into；Heavy metal Hg content of the present invention is relatively low, has no side effect, can be the longest
Phase uses.
Claims (1)
1. containing the facial film of gamma-aminobutyric acid, it is characterized in that the described facial film containing gamma-aminobutyric acid each composition and
Percentage by weight is: gamma amino acid/11 .50%, glycerol 10.25%, glycine betaine 12.60%, hydrolysis starch 8.95%, hyaluronate sodium
2.50%, Herba portulacae extract 15.60%, dipotaccium glycyrrhizate 3.50%, aminoacid 25.50%, butanediol 5.50%, ethyl hexyl ester
3.15%, fragrance 0.03%, pure water 10.92%；
Described gamma aminoacid, uses fermented by lactic acid bacteria to produce, through the catalytic action of glutamic acid decarboxylase organized enzyme, makes glutamic acid
Decarboxylation is gamma-aminobutyric acid, and the least concentration of glutamic acid is 10mmoL/L, and production gamma-aminobutyric acid, without any miscellaneous bacteria, reaches
Food sanitation standard；
Described glycine betaine, for the alkaloid extracted from Radix Betae；
Described Herba portulacae extracting solution, is that having of using that extraction the low temperature method stem from Herba Portulacae and leaf obtains is bioactive
Flavone and the mixture of Saponin；
Described dipotaccium glycyrrhizate, for the glycyrrhizic acid list potassium extracted from Radix Glycyrrhizae, glycyrrhizic acid dipotassium, the mixture of tripotassium glycyrrhetate；
Described aminoacid, uses lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, dried meat ammonia
In acid, glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, cysteine one
Kind or a kind of with mixture.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610391413.6A CN106038345A (en) | 2016-06-06 | 2016-06-06 | Mask containing gamma-aminobutyric acid |
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ID=57169449
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106880556A (en) * | 2017-03-27 | 2017-06-23 | 钱凤英 | A kind of non-pigmented composite skin care product of perfume-free and preparation method thereof |
| CN107362063A (en) * | 2017-09-11 | 2017-11-21 | 广州元美盛化妆品有限公司 | A kind of Water-free environment-friendlyurinal facial mask |
| CN107582468A (en) * | 2017-10-26 | 2018-01-16 | 广州市禾基生物科技有限公司 | A kind of antiallergic mask and preparation method thereof |
| CN110339101A (en) * | 2019-06-14 | 2019-10-18 | 广东萱嘉医品健康科技有限公司 | A kind of fermentation of seaweed liquid magma and the preparation method and application thereof containing γ-aminobutyric acid |
| CN112089665A (en) * | 2020-10-21 | 2020-12-18 | 广州华晟科创科技发展有限公司 | Essence lotion with effects of resisting aging and removing deep wrinkles and preparation method thereof |
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| CN1896259A (en) * | 2006-06-29 | 2007-01-17 | 中国农业大学 | Production of gamma-propalanine and its special reactive column |
| WO2008114732A1 (en) * | 2007-03-16 | 2008-09-25 | Shiseido Company Ltd. | Wrinkling-preventing and -modifying agent |
| CN105362091A (en) * | 2015-12-16 | 2016-03-02 | 华熙福瑞达生物医药有限公司 | Composition containing gamma-aminobutyric acid and hyaluronic acid and application of same to cosmetics |
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2016
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1896259A (en) * | 2006-06-29 | 2007-01-17 | 中国农业大学 | Production of gamma-propalanine and its special reactive column |
| WO2008114732A1 (en) * | 2007-03-16 | 2008-09-25 | Shiseido Company Ltd. | Wrinkling-preventing and -modifying agent |
| CN105362091A (en) * | 2015-12-16 | 2016-03-02 | 华熙福瑞达生物医药有限公司 | Composition containing gamma-aminobutyric acid and hyaluronic acid and application of same to cosmetics |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106880556A (en) * | 2017-03-27 | 2017-06-23 | 钱凤英 | A kind of non-pigmented composite skin care product of perfume-free and preparation method thereof |
| CN107362063A (en) * | 2017-09-11 | 2017-11-21 | 广州元美盛化妆品有限公司 | A kind of Water-free environment-friendlyurinal facial mask |
| CN107582468A (en) * | 2017-10-26 | 2018-01-16 | 广州市禾基生物科技有限公司 | A kind of antiallergic mask and preparation method thereof |
| CN107582468B (en) * | 2017-10-26 | 2020-11-10 | 广东省禾基生物科技有限公司 | Anti-allergic mask and preparation method thereof |
| CN110339101A (en) * | 2019-06-14 | 2019-10-18 | 广东萱嘉医品健康科技有限公司 | A kind of fermentation of seaweed liquid magma and the preparation method and application thereof containing γ-aminobutyric acid |
| CN110339101B (en) * | 2019-06-14 | 2022-06-10 | 广东萱嘉医品健康科技有限公司 | Seaweed fermentation broth protoplasm containing gamma-aminobutyric acid and preparation method and application thereof |
| CN112089665A (en) * | 2020-10-21 | 2020-12-18 | 广州华晟科创科技发展有限公司 | Essence lotion with effects of resisting aging and removing deep wrinkles and preparation method thereof |
| CN112089665B (en) * | 2020-10-21 | 2021-04-16 | 广州惜颜生物科技有限公司 | Essence lotion with effects of resisting aging and removing deep wrinkles and preparation method thereof |
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Application publication date: 20161026 |