CN105078876B - A kind of cicada fungus skin care compositions and preparation method thereof - Google Patents
A kind of cicada fungus skin care compositions and preparation method thereof Download PDFInfo
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Abstract
A kind of cicada fungus skin care compositions and preparation method thereof, which is characterized in that the composition contains resveratrol, artificial cicada extract, green-tea extract and Lu Yun gel inspissated juices as main active.
Description
Technical field
The application belongs to cosmetic technical field.
Technical background
Since the aging of skin is contacted with active oxygen radical with close, anti-oxidant is always cosmetic applications skill
The core content of art.The common anti-oxidant means of beauty product mainly apply all kinds of antioxidants, including SOD, vitamin C,
Vitamin E, various natural polyphenol class compounds etc..Although these antioxidants can efficiently remove all kinds of active oxygens, they are very
Hardly possible effectively reaches intracellular important site and maintains its anti-oxidant vigor.And these antioxidants often reduce cell
The generation of itself antioxidant, therefore the simple oxidative damage that effective protection cell is unable to using antioxidant.
The one kind of cicada fungus as cordyceps sinensis is a kind of traditional Chinese medicine, has the effects that antitumor, calm.Some researches show that cicada
Myriocin contained in flower extract and the like can promote the oxidation resistance of cell.And artificial cicada fungus also contains
Myriocin, and be more suitable for mass producing than wild cicada fungus.Such as：Have on the market at present and be much used to treat livestock fever disease
Parenteral solution, the effect of these parenteral solutions are respectively provided with certain dispelling wind-heat, removing summer-heat blood poison.
The presently found natural active matter that can promote cell intrinsic antioxidative ability is also fewer.Artificial cicada fungus extraction
Myriocin in object and the like itself does not have oxidation resistance, therefore will not reduce cell itself antioxidant
Generation, instead with apparent facilitation.Artificial cicada extract, which is applied in beauty skin care product, can improve product
Antioxidant and anti-aging effect, has a vast market prospect.
Invention content
The object of the present invention is to provide one kind, its active constituent can rapidly and accurately enter epithelial cell, and cell is promoted to resist
The generation of oxidation factor enhances the Oxidative Stress ability of cell itself, enhances skin oxidation resistance, increases skin collagen egg
White generation promotes the anti-oxidant skin care item of skin health youth.
The technical scheme is that：A kind of cicada fungus skin care compositions, which is characterized in that it contains following chief active
Ingredient：Resveratrol, artificial cicada extract, green-tea extract, aloe gel inspissated juice.
In one embodiment, the percentage composition of the main active of cicada fungus skin care compositions of the present invention is：White lamb's-quarters
Reed alcohol 0.1-0.5%, artificial cicada extract 0.1-0.5%, green-tea extract 0.2-0.5%, aloe gel inspissated juice 0.1-
0.5%.
In another preferred embodiment, the percentage composition of the main active of cicada fungus skin care compositions of the present invention
For：Resveratrol 0.3%, artificial cicada extract 0.3%, green-tea extract 0.4%, aloe gel inspissated juice 0.4%.
In one embodiment, cicada fungus skin care compositions of the invention also contains adjunct ingredient.
In another embodiment, the adjunct ingredient is selected from stearic acid, octadecyl alcolol, hexadecanol, polysorbate60, and the third three
Alcohol, triethanolamine, essence, deionized water and methyl p-methoxybenzoate it is one or more.
In one embodiment, the specific percentage composition of the adjunct ingredient is：Stearic acid 6.0-9.0%, octadecyl alcolol
2.7-3.0%, hexadecanol 2.7-3.0%, polysorbate60 0.5-1.5%, glycerine 4-6%, triethanolamine 0.1-1%, essence
0.001-0.005%, methyl p-methoxybenzoate 0.0001-0.0006%, surplus are deionized water.
In another preferred embodiment, the specific percentage composition of the adjunct ingredient is：Stearic acid 7.3%, 18
Alcohol 2.85%, hexadecanol 2.85%, polysorbate60 1%, glycerine 5.28%, triethanolamine 0.32%, essence 0.002%, to first
P-methoxybenzoic acid methyl esters 0.0005%, surplus are deionized water.
The invention also discloses a kind of preparation methods of cicada fungus skin care compositions, which is characterized in that it includes the following steps：
A, artificial cicada extract is prepared.Artificial cicada fungus after fermentation, directly carries out decompression suction filtration, collects ferment filtrate
With mycelium filter cake.Ferment filtrate is placed in 4 DEG C and saves backup.By mycelium filter cake by the ethyl alcohol of certain solid-liquid ratio addition 95%
Solution in 80 DEG C of immersions, repeats immersion after filtering, the solution after merging is added in macroreticular resin after merging filtrate elutes, and receives
Collect eluent, natural air drying it is dry artificial cicada extract.
B, by glycerine, triethanolamine, deionized water is mixed and heated to 95 DEG C, stirs evenly, and is pumped into emulsion reaction pot, is
A phases.
C, by stearic acid, octadecyl alcolol, hexadecanol, polysorbate60, artificial cicada extract is mixed and heated to 95 DEG C, and stirring is equal
It is even, it is B phases.
D, the A in reaction pot is added to B phases, continues to stir.
E, reaction pot is allowed to cool down, when being down to certain temperature, addition resveratrol, green-tea extract, aloe gel inspissated juice,
Essence, methyl p-methoxybenzoate add rear homogeneous, stir evenly, and homogeneous is to get finished product.
The invention has the advantages that the cicada fungus skin care compositions of the present invention using cicada extract as main component, adds
The formula of a variety of antioxidant activity components such as green-tea extract promotes the antioxidant activity of cell, by modern processing system
Into long-time service can effectively slow down skin oxidative aging, make skin high resilience, play the role of promoting to skin bright and clean.
Specific embodiment
In order to which goal of the invention, technological means, technique effect of the present invention etc. is made to be easier to understand, below in conjunction with specific implementation
The present invention is further explained for example
Embodiment 1
A kind of cicada fungus skin care compositions, which is characterized in that it contains following main active：Resveratrol 0.1%,
Artificial cicada extract 0.1%, green-tea extract 0.2%, aloe gel inspissated juice 0.1%.
Embodiment 2
A kind of cicada fungus skin care compositions, which is characterized in that it contains following main active：Resveratrol 0.5%,
Artificial cicada extract 0.5%, green-tea extract 0.5%, aloe gel inspissated juice 0.5%.
Embodiment 3
A kind of cicada fungus skin care compositions, which is characterized in that it contains following main active：Resveratrol 0.3%,
Artificial cicada extract 0.3%, green-tea extract 0.4%, aloe gel inspissated juice 0.4%.
Embodiment 4
A kind of cicada fungus skin care compositions, which is characterized in that it contains following ingredient：Resveratrol 0.3%, artificial cicada fungus carry
Take object 0.3%, green-tea extract 0.4%, aloe gel inspissated juice 0.4%, stearic acid 6.0%, octadecyl alcolol 2.7%, hexadecanol
2.7%, polysorbate60 0.5%, glycerine 4%, triethanolamine 0.1%, essence 0.001%, methyl p-methoxybenzoate
0.0001%, surplus is deionized water.
Embodiment 5
A kind of cicada fungus skin care compositions, which is characterized in that it contains following ingredient：Resveratrol 0.3%, artificial cicada fungus carry
Take object 0.3%, green-tea extract 0.4%, aloe gel inspissated juice 0.4%, stearic acid 9.0%, octadecyl alcolol 3.0%, hexadecanol
3.0%, polysorbate60 1.5%, glycerine 6%, triethanolamine 1%, essence 0.005%, methyl p-methoxybenzoate
0.0006%, surplus is deionized water.
Embodiment 6
A kind of cicada fungus skin care compositions, which is characterized in that it contains following ingredient：Resveratrol 0.3%, artificial cicada fungus carry
Take object 0.3%, green-tea extract 0.4%, aloe gel inspissated juice 0.4%, stearic acid 7.3%, octadecyl alcolol 2.85%, hexadecanol
2.85%, polysorbate60 1%, glycerine 5.28%, triethanolamine 0.32%, essence 0.002%, methyl p-methoxybenzoate
0.0005%, surplus is deionized water.
Embodiment 7
A kind of preparation method of cicada fungus skin care compositions, which is characterized in that it includes the following steps：
A, artificial cicada extract is prepared.Artificial cicada fungus after fermentation, directly carries out decompression suction filtration, collects ferment filtrate
With mycelium filter cake.Ferment filtrate is placed in 4 DEG C and saves backup.Mycelium filter cake is pressed into l：2 solid-liquid ratio adds in 95% ethyl alcohol
Solution impregnates 3h in 80 DEG C, immersion is repeated after filtering twice, merges ethanol extract and ferment filtrate.It will be molten after merging
Liquid add in macroporous resin adsorption column XAD-16, eluted with 95% ethyl alcohol, collect eluent, natural air drying it is dry artificial cicada
Flower extract.
B, by glycerine, triethanolamine, deionized water is mixed and heated to 95 DEG C, stirs evenly, and is pumped into emulsion reaction pot, is
A phases.
C, by stearic acid, octadecyl alcolol, hexadecanol, polysorbate60, artificial cicada extract is mixed and heated to 95 DEG C, and stirring is equal
It is even, it is B phases.
D, by the A phases in reaction pot under the conditions of insulated and stirred, B phases are slowly added to, continue stirring 1 hour.
E, reaction pot is allowed to cool down, when temperature is reduced to 45 DEG C, adds in resveratrol, green-tea extract, aloe gel concentration
Juice, essence, methyl p-methoxybenzoate add rear homogeneous, stir evenly, and homogeneous is to get finished product.
Embodiment 8
The antioxidation of cicada fungus skin care compositions.Experimental animal selects C57/BL63 monthly ages mouse 30, is randomly divided into 3
Group, every group 10.Normal group：Physiological saline (8ml/kg) is subcutaneously injected in daily mouse nape part；Skin aging model group：
12.5%D- galactolipins (8ml/kg) are subcutaneously injected in daily mouse nape part；Cicada fungus skin care item group：Shaver removes mouse dorsal body setae,
12.5%D- galactolipins (8ml/kg) are subcutaneously injected in daily mouse nape part, and 6 institute of embodiment is smeared after clear water cleaning skin of back
The cicada fungus skin care compositions stated.Each group mouse is put to death after 42 days, takes back skin tissues block.It is removed after physiological saline rinses
Subcutaneous fat and connective tissue, then shred skin histology, add in pre- cold saline, with electronic glass homogenizer in ice water
It is homogenized in bath.5 ultrasonications are carried out after homogenate in ice-water bath, 30 seconds every time, respectively obtain each mouse skin
Tissue homogenate.Hydrogen peroxide in tissue homogenate is measured using hydroperoxidase reagent box and hydroxyproline kit respectively
Enzymatic activity and hydroxyproline content.Each group mouse skin catalase activity and hydroxyproline content compare such as table 1.
1 cicada fungus skin care compositions of table is to the influence (n=of mouse aging skin catalase activity and hydroxyproline content
10)
* represent that there is significant difference (P compared with the control group<0.05), # represents poor with conspicuousness compared with model group
Different (P<0.05)
Since the major reason of skin aging is the accumulation of active oxygen radical, and the hydrogen peroxide under normal physiological conditions
Enzyme can effectively understand hydrogen peroxide, fight active oxygen radical.With age, intracellular hydrogen peroxide enzyme is reduced, body
Antioxidant defense decline, therefore it is to judge the important indicator of animal skin aging degree to measure catalase content.And
Hydroxyproline is the constituent that collagen is distinctive and important in skin, and hydroxyproline content declines in senile cell, draws
It plays skin collagen synthesis to reduce, skin occur, elasticity reduces and wrinkle increases, therefore it is hydroxyl to measure hydroxyproline content
Another important indicator of proline.
Experimental result is as shown in table 1, compared with normal group, skin aging model group mouse skin activity of catalase and
Hydroxyproline content is substantially reduced, and mouse skin catalase can be restored by being handled through present patent application product skin care compositions
Vigor and hydroxyproline content reach and level similar in normally group.Therefore present patent application product skin care compositions is anti-oxidant
Skin care item have enhancing skin oxidation resistance, promote collagen synthesis, have certain anti-aging effects.
Claims (4)
1. a kind of cicada fungus skin care compositions, which is characterized in that its active constituent is：Resveratrol, artificial cicada extract, green tea
Extract, aloe gel inspissated juice, wherein each component content is by weight percentage：Resveratrol 0.1-0.5%, artificial cicada fungus
Extract 0.1-0.5%, green-tea extract 0.2-0.5%, aloe gel inspissated juice 0.1-0.5%, the composition also contain
Adjunct ingredient, specific weight percentage are：Stearic acid 6.0-9.0%, octadecyl alcolol 2.7-3.0%, hexadecanol 2.7-3.0%,
Polysorbate60 0.5-1.5%, glycerine 4-6%, triethanolamine 0.1-1%, essence 0.001-0.005%, P-methoxybenzoic acid
Methyl esters 0.0001-0.0006%, surplus are deionized water.
2. the composition of claim 1, which is characterized in that wherein active component content is by weight percentage：Resveratrol
0.3%, artificial cicada extract 0.3%, green-tea extract 0.4%, aloe gel inspissated juice 0.4%.
3. the composition of claim 1, which is characterized in that the specific weight percentage of the adjunct ingredient is：Stearic acid
7.3%, octadecyl alcolol 2.85%, hexadecanol 2.85%, polysorbate60 1%, glycerine 5.28%, triethanolamine 0.32%, essence
0.002%, methyl p-methoxybenzoate 0.0005%, surplus is deionized water.
4. the preparation method of the cicada fungus skin care compositions of one of claim 1-3, which is characterized in that it includes the following steps：
A, artificial cicada extract is prepared：Artificial cicada fungus after fermentation, directly carries out decompression suction filtration, collects ferment filtrate and bacterium
Filament filter cake, ferment filtrate are placed in 4 DEG C and save backup, and mycelium filter cake is molten by the ethyl alcohol of certain solid-liquid ratio addition 95%
Liquid in 80 DEG C of immersions, repeats immersion after filtering, the solution after merging is added in macroreticular resin after merging filtrate elutes, and collects
Eluent, natural air drying it is dry artificial cicada extract；
B, by glycerine, triethanolamine, deionized water is mixed and heated to 95 DEG C, stirs evenly, and is pumped into emulsion reaction pot, is A phases；
C, by stearic acid, octadecyl alcolol, hexadecanol, polysorbate60, artificial cicada extract is mixed and heated to 95 DEG C, stirs evenly, and is B
Phase；
D, the A in reaction pot is added to B phases, continues stirring 1 hour；
E, reaction pot is allowed to cool down, when being down to 45 DEG C, adds in resveratrol, green-tea extract, aloe gel inspissated juice, essence is right
Methoxyl methyl benzoate adds rear homogeneous, stirs evenly, and homogeneous is to get finished product.
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| CN105726439B (en) * | 2016-02-05 | 2018-08-21 | 浙江理工大学 | Golden cicada spends skin whitening, moisturizing medicine cosmetic and preparation method thereof |
| WO2018184250A1 (en) * | 2017-04-08 | 2018-10-11 | 格兰比圣（深圳）科技有限公司 | Body wash and preparation method therefor |
| CN110200841A (en) * | 2019-05-23 | 2019-09-06 | 江苏农林职业技术学院 | A kind of cicada fungus tremella face mask liquid and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102240259A (en) * | 2010-05-14 | 2011-11-16 | 浙江泛亚生物医药股份有限公司 | Cicada extract shampoo and preparation thereof |
| CN102579279A (en) * | 2011-11-04 | 2012-07-18 | 江西农业大学 | Cosmetic formula comprising rhizomys sinensis gray and preparation method |
| CN103191042A (en) * | 2013-04-22 | 2013-07-10 | 黄勇 | Skin care agent capable of removing freckles, whitening, preventing wrinkles, moisturizing and resisting allergy and ageing |
| CN103340776A (en) * | 2013-06-20 | 2013-10-09 | 北华大学 | Magnolia sieboldii compound natural sunscreen cream and preparation method thereof |
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| DE102013205049A1 (en) * | 2013-03-21 | 2013-06-13 | Lr Health & Beauty Systems Gmbh | Antioxidant composition useful e.g. as agent for treating and/or preventing stress-related illnesses and for increasing mental performance, comprises polyphenol-rich plant extract, porphyrin, and additional compound including stilbenoids |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102240259A (en) * | 2010-05-14 | 2011-11-16 | 浙江泛亚生物医药股份有限公司 | Cicada extract shampoo and preparation thereof |
| CN102579279A (en) * | 2011-11-04 | 2012-07-18 | 江西农业大学 | Cosmetic formula comprising rhizomys sinensis gray and preparation method |
| CN103191042A (en) * | 2013-04-22 | 2013-07-10 | 黄勇 | Skin care agent capable of removing freckles, whitening, preventing wrinkles, moisturizing and resisting allergy and ageing |
| CN103340776A (en) * | 2013-06-20 | 2013-10-09 | 北华大学 | Magnolia sieboldii compound natural sunscreen cream and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| "Sunday Riley Bionic Anti-Aging Cream";佚名;《获取网址：http://www.cosdna.com/chs/cosmetic_988682923.html》;20120709;正文第1-2页 * |
| "地方药材金蝉花的研究进展";王琼等;《肿瘤学杂志》;20131221;第19卷(第3期);第227-230页 * |
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