CN106036902B - A kind of preparation method of quinoa leaf flavonoids health care buccal tablets - Google Patents
A kind of preparation method of quinoa leaf flavonoids health care buccal tablets Download PDFInfo
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- CN106036902B CN106036902B CN201610396283.5A CN201610396283A CN106036902B CN 106036902 B CN106036902 B CN 106036902B CN 201610396283 A CN201610396283 A CN 201610396283A CN 106036902 B CN106036902 B CN 106036902B
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- 240000006162 Chenopodium quinoa Species 0.000 title claims abstract description 75
- 230000036541 health Effects 0.000 title claims abstract description 38
- 229930003935 flavonoid Natural products 0.000 title claims abstract description 32
- 235000017173 flavonoids Nutrition 0.000 title claims abstract description 32
- 239000006189 buccal tablet Substances 0.000 title claims abstract description 31
- 150000002215 flavonoids Chemical class 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 239000000463 material Substances 0.000 claims abstract description 46
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
A kind of quinoa leaf flavonoids health care buccal tablets using quinoa leaf powder as main material, and add the nutritional ingredients such as roxburgh anoectochilus terminal bud powder, hazel pollen, omega-fatty acid thereto, various materials coordinated, and during the preparation process, mutually act synergistically.Nutritional ingredient, the activity of medicinal ingredient and a variety of biological enzyme in quinoa leaf have been effectively maintained using Vacuum Freezing & Drying Technology and spray drying technology in preparation process, maximally utilized material adequately.Finished product quinoa leaf flavonoids health care buccal tablets are full of nutrition, comprehensive, and containing effective pharmaceutical component such as flavonoids, plant polyphenol, reduced sugar, absorption easy to digest, health care is significant in efficacy.
Description
Technical field
The invention discloses a kind of preparation methods of quinoa leaf flavonoids health care buccal tablets, belong to technical field of health care food.
Background technique
Quinoa belongs to the annual self-pollinated plant of Chenopodiaceae Chenopodium, is base-forming food, thus it is possible to vary and it is acid in vivo, maintain body
Matter optimum state, protein content is high, and the amino acid with almost Perfect forms, rich in unsaturated fatty acid, flavonoids, dimension life
The multiple beneficials compound such as plain E, content of cellulose is high, cholesterol zero, low fat, low in calories, low glycemic, suitable diabetes B
People is edible, and quinoa is eaten for a long time, has fine preventive and therapeutic effect to heart disease, hypertension, hyperglycemia, hyperlipidemia etc..Due to quinoa
Nutritive value provide grain and in terms of outstanding role, FAO (Food and Agriculture Organization of the United Nation) thinks that quinoa is unique one kind
The solitary plant of human body basic nutrition demand can be met, and formal recommendation quinoa is the wholefood of the optimum mankind.Quinoa
Unique perfect nutraceutical that FAO (Food and Agriculture Organization of the United Nation) is assert, be known as " following super cereal ", " nutrition gold ",
" king of organic cereal " etc..Quinoa will gradually become the important directions of domestic and international novel functional food research and development.
People often pay close attention to its fruit in existing quinoa plant --- the development and utilization of quinoa, and quinoa leaf is often given up
It abandons, causes greatly to waste.Quinoa leaf flavonoids belong to natural biological flavone, and molecular weight is small, can pass through blood-brain barrier,
It is absorbed rapidly by human body, has and eliminate fatigue, protection blood vessel, preventing arteriosclerosis, dredging microcirculation, activation brain and other organs
The function of cell.
Roxburgh anoectochilus terminal bud is rich in ingredients such as taurine polysaccharide, with anti-aging, nourishing and protecting liver, the work for adjusting human body immunity of organism
With.On July 3rd, 2013, it is new raw-food material that country, which defends planning commission's website orientation bulletin approval roxburgh anoectochilus terminal bud,.
Corylus Betulaceae, hazel are the male flower of fibert, are distributed in the ground such as northeast, North China, are remembered according to " dictionary of medicinal plant "
It carries, kernel, that is, fibert of hazel has in tune, whets the appetite, improving eyesight, treats physically weak after being ill, hypoglycemic, protection liver and other effects.Hazel is logical
Scavenging activated oxygen and lipoid peroxidization resistant are crossed, liver is protected and restores the normal function carbohydrate metabolism of liver, corrects sugared generation
It thanks to disorder, reduces blood glucose.Hazel can reduce free radical and its metabolite to the harmful effect of each tissue, can improve diabetes
Carbohydrate metabolism disturbance in patient liver enhances the function of liver cell glycogen biosynthesis, to reduce blood glucose.
Supercritical carbon dioxide extraction method is a kind of novel extraction and separation technology, using the titanium dioxide of supercriticality
Carbon substitutes traditional chemical solvent as spe medium, and fat-soluble effective component is extracted out of plant, animal and microbial body.It should
The characteristics of technology is: 1, carbon dioxide is tasteless, odorless, nontoxic, chemical inertness, and free from environmental pollution and product does not end up at production
In product and material residue, not only product quality is high, but also entire production process does not generate any pollution；2, operating condition is mild, especially
The extraction of heat-sensitive ingredients in material can make extract keep its original flavor, this is that other methods are insurmountable；3,
Supercritical carbon dioxide extraction medium has both the mass transfer performances of liquid and the diffusivity of gas, and penetration is strong, and extraction efficiency is more traditional
Extracting process greatly improves；4, technology collection extraction is located away from one, greatly shortens process flow；5, carbon dioxide is inexpensive easily
, it is nonflammable explosive, recycle simple and convenient, the saving energy；6, easy to operate, by its operating condition (pressure and temperature)
Changing can be changed its solubility and realizes selective extraction.
Vacuum Freezing & Drying Technology is that wet stock or solution are frozen into solid-state at a lower temperature, then under vacuum
So that moisture therein is directly sublimed into gaseous state without liquid, finally makes the dry technology of material dewatering.
Currently, the domestic deep processed product exploitation in relation to quinoa extremely lacks, far from the needs for meeting health care market, use
Quinoa leaf is that raw material progress deep processed product more lacks, in addition, quinoa leaf materials facilitate quantity big, exploitation quinoa Ye is always yellow
Ketone health care buccal tablets have unique market orientation and urgent need.
Summary of the invention
The technical problem to be solved in the present invention are as follows: using quinoa leaf as main material, auxiliary addition roxburgh anoectochilus terminal bud powder and hazel pollen etc.
Nutriment, using the preparations such as Vacuum Freezing & Drying Technology and spray drying technology and processing technology, prepare it is a kind of it is full of nutrition,
Resource utilization is high, absorption easy to digest, health care quinoa leaf flavonoids health care buccal tablets significant in efficacy, to improve the utilization of quinoa leaf
Value.
The present invention is to solve the above problems, used technical solution are as follows: a kind of system of quinoa leaf flavonoids health care buccal tablets
Preparation Method, comprising the following steps:
Step 1: it is cold to be placed in progress vacuum under conditions of temperature is -55 ~ -65 DEG C after taking the quinoa leaf of fresh picking to clean
Dry 22 ~ 26h is lyophilized, later, transposition is ground into the particle of 30~50 mesh in pulverizer, spare；
Step 2: according to parts by weight, taking quinoa leaf particle made from 60-80 parts of step 1, and according to the feed liquid of 1:40
Than the ethanol solution that mass concentration is 70% being added into quinoa leaf particle, later, by obtained mixed material transposition in ultrasound
In wave processor, regulation power is 160~200W, carries out 10~15min of ultrasonication；
Step 3: by the material transposition after step 2 ultrasonication in supercritical carbon dioxide extracting axe, in temperature
It is 40~50 DEG C, pressure carries out 1~2h of extraction under the conditions of being 30~40MPa, obtains liquid medicinal extract, spare；
Step 4: according to parts by weight, weighing 2-5 parts of roxburgh anoectochilus terminal bud powder, 2-5 parts of hazel pollen, 2-10 parts of ω -3 fat respectively
Acid, 7-9 parts of talcum powder, 2-5 portions of mannitol, 1-3 parts of menthols and a certain amount of dextrin are added to liquid medicinal extract made from step 3
In, then gained mixture is put into the homogenizer that pressure is 40~100MPa and is carried out homogeneous 2-3 times, mixed material is obtained,
It is spare；
Step 5: using tablet press machine that mixed material made from step 4 is tabletted, later, aseptic packaging to get
Finished product quinoa leaf flavonoids health care buccal tablets.
The temperature of vacuum freeze drying is -60 DEG C in the step 1, and the time is for 24 hours.
In step 4, the mass ratio of added dextrin and liquid medicinal extract is 1:1.
The roxburgh anoectochilus terminal bud powder added in the step 4 is prepared by following methods: being taken fresh roxburgh anoectochilus terminal bud, after cleaning, draining, is set
Carried out in beater mashing processing 5-8min gained slurry is put into fermentor later, thereto be added artificial yeast and
Lemon juice controlled at 35 ~ 40 DEG C, is sealed fermentation 24-40h and then goes out to tunning after mixing evenly
Bacterium processing, later, transposition is in spray dryer, and the inlet temperature of adjustable spraying drying machine is 150-180 DEG C, intake 4-
6m3/ min, air draft temperature are 85 DEG C, are spray-dried with the feed rate of 1100-1120mL/h, until material is aqueous after dry
Amount≤4%.
The additional amount of the artificial yeast is the 2-3% of stock quality, and the additional amount of lemon juice is the 4-5% of stock quality.
The beneficial effects of the present invention are:
1) a kind of quinoa leaf flavonoids health care buccal tablets provided by the invention and preparation method thereof, method is easy to operate, material
Utilization rate is high, is suitble to industrial production.Vacuum freeze drying and super critical CO 2 technology have been effectively maintained in quinoa leaf
The activity of nutritional ingredient, medicinal ingredient and a variety of biological enzyme, maximally utilizes material adequately, to substantially reduce life
Cost is produced, while improving the activity of general flavone, conducive to being digested, it is made to eliminate fatigue, protect blood vessel, anti-dynamic
Arteries and veins hardening, the function of dredging microcirculation, activation brain and other cells of organs are more significant, have very big economic value.
2) quinoa leaf flavonoids health care buccal tablets prepared by the present invention are added using quinoa leaf powder as main material, and thereto
Add the nutritional ingredients such as roxburgh anoectochilus terminal bud powder, hazel pollen, omega-fatty acid, various materials coordinated, and during the preparation process, mutually assist
Same-action not only increases the comprehensive utilization ratio of quinoa leaf, also sufficiently, completely protects the nutritional ingredient in the raw materials such as quinoa leaf
Stay, and be concentrated, be added in finished product, keep finished product quinoa leaf flavonoids health care buccal tablets full of nutrition, comprehensive, containing flavonoids,
Effective pharmaceutical component such as plant polyphenol, reduced sugar, absorption easy to digest, health care are significant in efficacy.
3) present invention quinoa leaf material is freeze-dried and is dried in vacuo after also crushed, ultrasound and homogeneous place
Step is managed, the loss of general flavone, remains when the freeze-drying and vacuum drying of lower temperature greatly reduce the drying of quinoa leaf
The original general flavone ingredient of quinoa leaf；Pulverization process realizes the broken of quinoa leaf cell, and Chenopodiaceae is furthermore achieved in ultrasonic treatment
The height of wheat leaf wall is broken, and two steps be combined with each other, and ensure that the efficient extraction of flavonoid compound in quinoa leaf cell,
It is set to be extracted out to greatest extent；The high-pressure homogeneous mixture made is more uniform, and ratio is more consistent, is advantageously implemented
The uniformity of the lozenge obtained after subsequent tabletting keeps final product quality more stable.
4) carbon dioxide that supercritical carbon dioxide extracting step of the invention uses is tasteless, odorless, nontoxic, chemistry is lazy
Property, free from environmental pollution and general flavone do not end up in general flavone and material residue, and not only general flavone quality is high, but also entirely produces
Journey does not generate any pollution.Operating condition is mild, and general flavone can be made to keep its original flavor, this is that other methods can not solve
Certainly, supercritical carbon dioxide extraction medium has both the mass transfer performances of liquid and the diffusivity of gas, and penetration is strong, extraction efficiency compared with
Conventional extraction process greatly improves, and technology collection extraction is located away from one, greatly shortens process flow, and carbon dioxide is inexpensive easily
, it is nonflammable explosive, simple and convenient, the saving energy is recycled, it is easy to operate, pass through the control to its operating condition (pressure and temperature)
System can extract general flavone.
5) preparation method of a kind of quinoa leaf flavonoids health care buccal tablets disclosed by the invention, in the preparation process of roxburgh anoectochilus terminal bud powder
In also added with to after mashing roxburgh anoectochilus terminal bud slurries carry out fermentation process the step of, during the fermentation, in fresh roxburgh anoectochilus terminal bud
Complicated biochemical reaction can occur under anaerobic for substance, and the fungi substance for generation of fermenting can make in roxburgh anoectochilus terminal bud
A certain amount of decomposition occurs for carbohydrate content, so as to improve the distribution of glucide type, it is made to be more advantageous to by human consumption, inhale
It receives.During the fermentation, a certain amount of lemon juice is added in slurries, the acidic materials in lemon juice can accelerate to ferment into
Journey improves production efficiency.
Specific embodiment
Below with reference to embodiment, the present invention is further illustrated:
A kind of preparation method of quinoa leaf flavonoids health care buccal tablets, comprising the following steps:
Step 1: it is cold to be placed in progress vacuum under conditions of temperature is -55 ~ -65 DEG C after taking the quinoa leaf of fresh picking to clean
Dry 22 ~ 26h is lyophilized, later, transposition is ground into the particle of 30~50 mesh in pulverizer, spare；
Step 2: according to parts by weight, taking quinoa leaf particle made from 60-80 parts of step 1, and according to the feed liquid of 1:40
Than the ethanol solution that mass concentration is 70% being added into quinoa leaf particle, later, by obtained mixed material transposition in ultrasound
In wave processor, regulation power is 160~200W, carries out 10~15min of ultrasonication；
Step 3: by the material transposition after step 2 ultrasonication in supercritical carbon dioxide extracting axe, in temperature
It is 40~50 DEG C, pressure carries out 1~2h of extraction under the conditions of being 30~40MPa, obtains liquid medicinal extract, spare；
Step 4: according to parts by weight, weighing 2-5 parts of roxburgh anoectochilus terminal bud powder, 2-5 parts of hazel pollen, 2-10 parts of ω -3 fat respectively
Acid, 7-9 parts of talcum powder, 2-5 portions of mannitol, 1-3 parts of menthols and a certain amount of dextrin are added to liquid medicinal extract made from step 3
In, the mass ratio of added dextrin and liquid medicinal extract is 1:1, and gained mixture is then put into the homogeneous that pressure is 40~100MPa
It is carried out homogeneous 2-3 times in machine, which has to be uniformly mixed, and obtains mixed material, spare；
Step 5: it is using tablet press machine that mixed material made from step 4 is tabletted, later, aseptically select
It is packed with vacuum packing machine to get finished product quinoa leaf flavonoids health care buccal tablets.
The roxburgh anoectochilus terminal bud powder added in the step 4 is prepared by following methods: being taken fresh roxburgh anoectochilus terminal bud, after cleaning, draining, is set
Carried out in beater mashing processing 5-8min gained slurry is put into fermentor later, thereto be added artificial yeast and
Lemon juice, wherein the additional amount of artificial yeast is the 2-3% of stock quality, and the additional amount of lemon juice is the 4-5% of stock quality,
After mixing evenly, controlled at 35 ~ 40 DEG C, it is sealed fermentation 24-40h, then, sterilization treatment is carried out to tunning,
Later, transposition is in spray dryer, and the inlet temperature of adjustable spraying drying machine is 150-180 DEG C, intake 4-6m3/
Min, air draft temperature are 85 DEG C, are spray-dried with the feed rate of 1100-1120mL/h, until material moisture after dry≤
4%.
Quinoa leaf flavonoids health care buccal tablets prepared by the present invention need to limit roxburgh anoectochilus terminal bud daily content no more than 5g.
Meanwhile infant and pregnant woman's inedibility.
Embodiment 1:
A kind of preparation method of quinoa leaf flavonoids health care buccal tablets, comprising the following steps:
Step 1: it is dry to be placed in progress vacuum refrigeration under conditions of temperature is -55 DEG C after taking the quinoa leaf of fresh picking to clean
Dry 26h, later, transposition are ground into the particle of 50 mesh in pulverizer, spare；
Step 2: according to parts by weight, quinoa leaf particle made from 80 parts of step 1 is taken, and according to the solid-liquid ratio of 1:40,
The ethanol solution that mass concentration is 70% is added into quinoa leaf particle, later, by obtained mixed material transposition at ultrasonic wave
It manages in device, regulation power 160W, carries out ultrasonication 15min；
Step 3: by the material transposition after step 2 ultrasonication in supercritical carbon dioxide extracting axe, in temperature
It is 50 DEG C, pressure carries out extraction 2h under the conditions of being 30MPa, obtains liquid medicinal extract, spare；
Step 4: according to parts by weight, weighing 5 parts of roxburgh anoectochilus terminal bud powder, 2 parts of hazel pollen, 2 parts of omega-fatty acids, 7 parts of cunnings respectively
Mountain flour, 5 portions of mannitol, 3 parts of menthols and liquid medicinal extract made from step 3 is added to the dextrin of liquid medicinal extract equal quality
In, then gained mixture is put into the homogenizer that pressure is 40MPa and is carried out homogeneous 3 times, which has to be uniformly mixed,
Mixed material is obtained, it is spare；
Wherein roxburgh anoectochilus terminal bud powder is prepared by following methods: being taken fresh roxburgh anoectochilus terminal bud, after cleaning, draining, is placed in beater and carries out
Gained slurry is put into fermentor by mashing processing 8min later, artificial yeast and lemon juice is added thereto, wherein artificial
The additional amount of yeast is the 3% of stock quality, and the additional amount of lemon juice is the 4% of stock quality, after mixing evenly, controlled at
It 40 DEG C, is sealed fermentation for 24 hours, then, sterilization treatment is carried out to tunning, later, transposition is adjusted in spray dryer
The inlet temperature of spray dryer is 180 DEG C, intake 6m3/ min, air draft temperature is 85 DEG C, with the feed rate of 1120mL/h
It is spray-dried, until material moisture≤4% after dry.
Step 5: it is using tablet press machine that mixed material made from step 4 is tabletted, later, aseptically select
It is packed with vacuum packing machine to get finished product quinoa leaf flavonoids health care buccal tablets.
Embodiment 2:
A kind of preparation method of quinoa leaf flavonoids health care buccal tablets, comprising the following steps:
Step 1: it is dry to be placed in progress vacuum refrigeration under conditions of temperature is -65 DEG C after taking the quinoa leaf of fresh picking to clean
Dry 22h, later, transposition are ground into the particle of 30 mesh in pulverizer, spare；
Step 2: according to parts by weight, quinoa leaf particle made from 60 parts of step 1 is taken, and according to the solid-liquid ratio of 1:40,
The ethanol solution that mass concentration is 70% is added into quinoa leaf particle, later, by obtained mixed material transposition at ultrasonic wave
It manages in device, regulation power 200W, carries out ultrasonication 10min；
Step 3: by the material transposition after step 2 ultrasonication in supercritical carbon dioxide extracting axe, in temperature
It is 40 DEG C, pressure carries out extraction 1h under the conditions of being 40MPa, obtains liquid medicinal extract, spare；
Step 4: according to parts by weight, weighing 2 parts of roxburgh anoectochilus terminal bud powder, 5 parts of hazel pollen, 10 parts of omega-fatty acids, 9 parts respectively
Talcum powder, 2 portions of mannitol, 1 part of menthol and the leaching of liquid made from step 3 is added to the dextrin of liquid medicinal extract equal quality
In cream, then gained mixture is put into the homogenizer that pressure is 100MPa and is carried out homogeneous 2 times, it is equal which has to mixing
It is even, mixed material is obtained, it is spare；
Wherein roxburgh anoectochilus terminal bud powder is prepared by following methods: being taken fresh roxburgh anoectochilus terminal bud, after cleaning, draining, is placed in beater and carries out
Gained slurry is put into fermentor by mashing processing 5min later, artificial yeast and lemon juice is added thereto, wherein artificial
The additional amount of yeast is the 2% of stock quality, and the additional amount of lemon juice is the 5% of stock quality, after mixing evenly, controlled at
35 DEG C, it is sealed fermentation 40h, then, sterilization treatment is carried out to tunning, later, transposition is adjusted in spray dryer
The inlet temperature of spray dryer is 150 DEG C, intake 4m3/ min, air draft temperature is 85 DEG C, with the feed rate of 1100mL/h
It is spray-dried, until material moisture≤4% after dry.
Step 5: it is using tablet press machine that mixed material made from step 4 is tabletted, later, aseptically select
It is packed with vacuum packing machine to get finished product quinoa leaf flavonoids health care buccal tablets.
Embodiment 3:
A kind of preparation method of quinoa leaf flavonoids health care buccal tablets, comprising the following steps:
Step 1: it is dry to be placed in progress vacuum refrigeration under conditions of temperature is -60 DEG C after taking the quinoa leaf of fresh picking to clean
It is dry for 24 hours, later, transposition is ground into the particle of 40 mesh in pulverizer, spare；
Step 2: according to parts by weight, quinoa leaf particle made from 70 parts of step 1 is taken, and according to the solid-liquid ratio of 1:40,
The ethanol solution that mass concentration is 70% is added into quinoa leaf particle, later, by obtained mixed material transposition at ultrasonic wave
It manages in device, regulation power 180W, carries out ultrasonication 12min；
Step 3: by the material transposition after step 2 ultrasonication in supercritical carbon dioxide extracting axe, in temperature
It is 45 DEG C, pressure carries out extraction 1.5h under the conditions of being 35MPa, obtains liquid medicinal extract, spare；
Step 4: according to parts by weight, weighing 3 parts of roxburgh anoectochilus terminal bud powder, 4 parts of hazel pollen, 8 parts of omega-fatty acids, 8 parts of cunnings respectively
Mountain flour, 4 portions of mannitol, 2 parts of menthols and liquid medicinal extract made from step 3 is added to the dextrin of liquid medicinal extract equal quality
In, then gained mixture is put into the homogenizer that pressure is 60MPa and is carried out homogeneous 3 times, which has to be uniformly mixed,
Mixed material is obtained, it is spare；
Wherein roxburgh anoectochilus terminal bud powder is prepared by following methods: being taken fresh roxburgh anoectochilus terminal bud, after cleaning, draining, is placed in beater and carries out
Gained slurry is put into fermentor by mashing processing 6min later, artificial yeast and lemon juice is added thereto, wherein artificial
The additional amount of yeast is the 2.5% of stock quality, and the additional amount of lemon juice is the 4.5% of stock quality, after mixing evenly, control temperature
Degree be 38 DEG C, be sealed fermentation 28h, then, to tunning carry out sterilization treatment, later, transposition in spray dryer,
The inlet temperature of adjustable spraying drying machine is 160 DEG C, intake 5m3/ min, air draft temperature is 85 DEG C, with the charging of 1115mL/h
Flow is spray-dried, until material moisture≤4% after dry.
Step 5: it is using tablet press machine that mixed material made from step 4 is tabletted, later, aseptically select
It is packed with vacuum packing machine to get finished product quinoa leaf flavonoids health care buccal tablets.
Certain result measurement experiment is carried out to quinoa leaf flavonoids health care buccal tablets prepared by the present invention below.
Experiment 1
The quinoa leaf powder of equivalent is individually placed in the instrument of two kinds of A, B extraction modes, wherein A group extraction mode is this hair
Extracting process in bright, B group extraction mode are soxhlet extraction.Sufficiently general flavone content is measured after extraction.
Experimental result: the general flavone content in general flavone content ratio B group in A group is higher by 15%, this illustrates overcritical dioxy
Change the extraction that carbon extraction mode effectively raises general flavone in quinoa leaf.
Experiment 2
The identical people of 200 health status is divided into A, B group, wherein A group eats health care buccal tablets produced by the present invention, B group
Health care buccal tablets produced by the present invention are not eaten.Investigation of health conditions is carried out after 30 days.
The result shows that A group eats the health care buccal tablets that the present invention produces, physical condition improves significantly, this says
The bright present invention plays the effect for improving immunity, acts on promoting health, long-term use can preventing arteriosclerosis.
Claims (4)
1. a kind of preparation method of quinoa leaf flavonoids health care buccal tablets, which comprises the following steps:
Step 1: it is dry to be placed in progress vacuum refrigeration under conditions of temperature is -55 ~ -65 DEG C after taking the quinoa leaf of fresh picking to clean
Dry 22 ~ 26h, later, transposition are ground into the particle of 30~50 mesh in pulverizer, spare；
Step 2: according to parts by weight, quinoa leaf particle made from 60-80 parts of step 1 is taken, and according to the solid-liquid ratio of 1:40, to
The ethanol solution that mass concentration is 70% is added in quinoa leaf particle, later, by obtained mixed material transposition in ultrasonication
In device, regulation power is 160~200W, carries out 10~15min of ultrasonication；
Step 3: being 40 in temperature by the material transposition after step 2 ultrasonication in supercritical carbon dioxide extracting axe
~50 DEG C, pressure carries out 1~2h of extraction under the conditions of being 30~40MPa, obtains liquid medicinal extract, spare；
Step 4: according to parts by weight, weighing 2-5 parts of roxburgh anoectochilus terminal bud powder, 2-5 parts of hazel pollen, 2-10 parts of omega-fatty acids, 7- respectively
9 parts of talcum powder, 2-5 portions of mannitol, 1-3 parts of menthols and a certain amount of dextrin are added in liquid medicinal extract made from step 3, so
Gained mixture is put into the homogenizer that pressure is 40~100MPa afterwards and is carried out homogeneous 2-3 times, mixed material is obtained, it is spare；
Wherein, roxburgh anoectochilus terminal bud powder is prepared by following methods: being taken fresh roxburgh anoectochilus terminal bud, after cleaning, draining, is placed in beater and is beaten
Gained slurry is put into fermentor by processing 5-8min later, and artificial yeast and lemon juice are added thereto, after mixing evenly,
Controlled at 35 ~ 40 DEG C, be sealed fermentation 24-40h, then, to tunning carry out sterilization treatment, later, transposition in
In spray dryer, the inlet temperature of adjustable spraying drying machine is 150-180 DEG C, intake 4-6m3/ min, air draft temperature are 85
DEG C, it is spray-dried with the feed rate of 1100-1120mL/h, until material moisture≤4% after dry；
Step 5: using tablet press machine that mixed material made from step 4 is tabletted, later, aseptic packaging is to get finished product
Quinoa leaf flavonoids health care buccal tablets.
2. a kind of preparation method of quinoa leaf flavonoids health care buccal tablets as described in claim 1, it is characterised in that: the step
The temperature of vacuum freeze drying is -60 DEG C in one, and the time is for 24 hours.
3. a kind of preparation method of quinoa leaf flavonoids health care buccal tablets as described in claim 1, it is characterised in that: in step 4
In, the mass ratio of added dextrin and liquid medicinal extract is 1 ﹕ 1.
4. a kind of preparation method of quinoa leaf flavonoids health care buccal tablets as described in claim 1, it is characterised in that: described artificial
The additional amount of yeast is the 2-3% of stock quality, and the additional amount of lemon juice is the 4-5% of stock quality.
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| CN107760058A (en) * | 2017-11-30 | 2018-03-06 | 广西南宁栩兮科技有限公司 | The extracting method of haematochrome in a kind of rambutan shell |
| CN112386620A (en) * | 2020-11-24 | 2021-02-23 | 安阳工学院 | Method for extracting quinoa flavone |
| CN112618658A (en) * | 2020-12-29 | 2021-04-09 | 联和东浩(厦门)药业有限公司 | Processing method of traditional Chinese medicine decoction pieces containing anoectochilus formosanus |
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