CN105999428A - 一种具有抗菌止血功效的防粘连膜 - Google Patents

一种具有抗菌止血功效的防粘连膜 Download PDF

Info

Publication number
CN105999428A
CN105999428A CN201610427575.0A CN201610427575A CN105999428A CN 105999428 A CN105999428 A CN 105999428A CN 201610427575 A CN201610427575 A CN 201610427575A CN 105999428 A CN105999428 A CN 105999428A
Authority
CN
China
Prior art keywords
parts
effects
antibacterial anti
stopping bleeding
resisting bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201610427575.0A
Other languages
English (en)
Inventor
董荣琴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUZHOU KEDA CHEMICAL FUEL Co Ltd
Original Assignee
HUZHOU KEDA CHEMICAL FUEL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HUZHOU KEDA CHEMICAL FUEL Co Ltd filed Critical HUZHOU KEDA CHEMICAL FUEL Co Ltd
Priority to CN201610427575.0A priority Critical patent/CN105999428A/zh
Publication of CN105999428A publication Critical patent/CN105999428A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/028—Other inorganic materials not covered by A61L31/022 - A61L31/026
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/428—Vitamins, e.g. tocopherol, riboflavin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

本发明公开了一种具有抗菌止血功效的防粘连膜，它包括按照重量份数计的如下组分：聚丁二酸丁二醇酯30‑50份、黄芪胶8‑12份、三黄粉6‑9份、天花粉3‑5份、芦荟素3‑7份、羧甲基纤维素钠5‑10份、甘草酸二钾6‑10份、赤芍粉7‑11份、冰片10‑18份、甲基丙烯酸羟丙酯5‑8份、维生素1‑5份。本发明的一种具有抗菌止血功效的防粘连膜具有抗菌止血的功效，生物相容性好，可降解，使用方便，生物可降解性良好，对组织无刺激，对人体无毒无害，可以广泛应用与医疗领域。

Description

一种具有抗菌止血功效的防粘连膜
技术领域
本发明属于生物医用材料领域，具体涉及一种具有抗菌止血功效的防粘连膜。
背景技术
生物材料是用于人体组织和器官的诊断、修复或增进其功能的一类高技术材料，即用于取代、修复活组织的天然或人造材料，其作用药物不可替代。生物材料能执行、增进或替换因疾病、损伤等失去的某种功能，而不能恢复缺陷部位。自90年代后期以来，世界生物材料科学和技术迅速发展，即使在当今全球经济低迷的大环境下，生物材料依然保持着每年13％高速增长，充分体现了其强大的生命力和广阔的发展前景。现代医学正向再生和重建被损坏的人体组织和器官、恢复和增进人体生理功能、个性化和微创治疗等方向发展。传统的无生命的医用金属、高分子、生物陶瓷等常规材料已不能满足医学发展的要求，生物医学材料科学与工程面临着新的机遇与挑战。未来，生物医用材料的市场占有率大有可能将赶上药物。因此，加强生物医用材料的临床应用研究和推广应用，重点发展我国生物医用材料的研究、开发、生产、营销紧密结合的一体化体系是当务之急。实际上，国家当前在生物材料科学基础研究方面已经取得了重大突破进展，走在了世界先进行列，但产业化水平尚待提高，产业规模小、发展相对滞后，还不能满足全民医疗保健的实际需要。在国家政策、经济的大力支持下，我国生物材料的产业化发展将提速。企业应增强自主创新的能力，进一步解决依靠进口的局面，同时加大出口力度，实现跨越发展，扩大中国生物材料产品在国际上的影响力。
生物材料应用广泛，品种很多，其分类方法也很多。生物材料包括金属材料(如碱金属及其合金等)、无机材料(生物活性陶瓷，羟基磷灰石等)和有机材料三大类。有机材料中主要是高分子集合物材料，高分子材料通常按材料属性分为合成高分子材料(聚氨酯、聚酯、聚乳酸、聚乙醇酸、乳酸乙醇酸共聚物及其他医用合成塑料和橡胶等)、天然高分子材料(如胶原、丝蛋白、纤维素、壳聚糖等)；根据材料的用途，这些材料又可以分为生物惰性(bioinert)、生物活性(bioactive)或生物降解(biodegradable)材料，高分子聚合物中，根据降解产物能否被机体代谢和吸收，降解型高分子又可分为生物可吸收性和生物不可吸收性。根据材料与血液接触后对血液成分、性能的影响状态则分为血液相容性聚合物和血液不相容性。根据材料对机体细胞的亲和性和反映情况，可分为生物相容性和生物不相容性聚合物等。防粘连膜就属于高分子材料中的一种，防粘连膜是一种常见的医药耗材，用以防止术后与组织修复无关的不良粘连，以免造成组织变形、阻塞、扭曲、引发严重的后果，例如引起疼痛甚至生物组织的功能性障碍，在严重的情况下甚至还需要另外的手术剥离不良粘连。因此，对于粘连膜的性能提出了很高的要求，一方面，需要粘连膜具有良好的弹性，不损伤组织；另一方面，需要粘连膜容易分离，而且具有良好的机械性能。术后粘连是腹腔、盆腔、心脏等部位手术治疗中最常见、最棘手的问题，它不仅会引起严重的并发症，同时也是二次手术后并发症出现概率明显上升的主要原因。通常，在手术伤口缝合之前，外科医生会将一层具有物理隔离作用的防粘连膜放在经过手术的组织或器官之间，从而防止组织与器官粘连的发生。然而现有的防粘连膜存在一些不足，如不可降解使用后难处理，作用单一等。因此，需要研发出一种可降解并具有抗菌止血功效的防粘连膜。
发明内容
本发明的目的在于提供一种具有抗菌止血功效的防粘连膜。
为了实现上述目的，本发明提供了一种具有抗菌止血功效的防粘连膜，包括按照重量份数计的如下组分：聚丁二酸丁二醇酯30-50份、黄芪胶8-12份、三黄粉6-9份、天花粉3-5份、芦荟素3-7份、羧甲基纤维素钠5-10份、甘草酸二钾6-10份、赤芍粉7-11份、冰片10-18份、甲基丙烯酸羟丙酯5-8份、维生素1-5份。
其还包含六偏磷酸钠1-4份。
其还包含马来酸酐2-6份。
其还包含卡波姆3-5份。
其制备方法为：按重量份称取各原料，将原料加入容器中，于室温下超声1-6h后，然后加热至80-110℃，搅拌1-3h后，静置24h脱泡，倒在玻璃模具内，使膜液自然流平，水平置于鼓风干燥箱中30-50℃恒温干燥3-12小时，将模具取出，冷却，室温下放置12小时，揭膜，即得具有抗菌止血功效的防粘连膜。
有益效果：本发明的一种具有抗菌止血功效的防粘连膜具有抗菌止血的功效，生物相容性好，可降解，使用方便，生物可降解性良好，对组织无刺激，对人体无毒无害，可以广泛应用与医疗领域。
具体实施方式
实施例1
本实施例的具有抗菌止血功效的防粘连膜，包括按照重量份数计的如下组分：聚丁二酸丁二醇酯30份、黄芪胶8份、三黄粉6份、天花粉3份、芦荟素3份、羧甲基纤维素钠5份、甘草酸二钾6份、赤芍粉7份、冰片10份、甲基丙烯酸羟丙酯5份、维生素1份。
实施例2
本实施例的具有抗菌止血功效的防粘连膜，包括按照重量份数计的如下组分：聚丁二酸丁二醇酯50份、黄芪胶12份、三黄粉9份、天花粉5份、芦荟素7份、羧甲基纤维素钠10份、甘草酸二钾10份、赤芍粉11份、冰片18份、甲基丙烯酸羟丙酯8份、维生素5份、六偏磷酸钠4份。
实施例3
本实施例的具有抗菌止血功效的防粘连膜，包括按照重量份数计的如下组分：聚丁二酸丁二醇酯30份、黄芪胶8份、三黄粉6份、天花粉3份、芦荟素3份、羧甲基纤维素钠5份、甘草酸二钾6份、赤芍粉7份、冰片10份、甲基丙烯酸羟丙酯5份、维生素1份、六偏磷酸钠1份、马来酸酐2份。
实施例4
本实施例的具有抗菌止血功效的防粘连膜，包括按照重量份数计的如下组分：聚丁二酸丁二醇酯50份、黄芪胶12份、三黄粉9份、天花粉5份、芦荟素7份、羧甲基纤维素钠10份、甘草酸二钾10份、赤芍粉11份、冰片18份、甲基丙烯酸羟丙酯8份、维生素5份、六偏磷酸钠4份、马来酸酐6份、卡波姆5份。
以上所述,仅是本发明的较佳实施例而已,并非对本发明作任何形式上的限制,虽然本发明已以较佳实施例揭露如上,然而并非用以限定本发明，任何熟悉本专业的技术人员,在不脱离本发明技术方案范围内,当可利用上述揭示的技术内容作出些许更动或修饰为等同变化的等效实施例,但凡是未脱离本发明技术方案的内容,依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰,均仍属于本发明技术方案的范围内。

Claims (4)

1.一种具有抗菌止血功效的防粘连膜，其特征在于包括按照重量份数计的如下组分：聚丁二酸丁二醇酯30-50份、黄芪胶8-12份、三黄粉6-9份、天花粉3-5份、芦荟素3-7份、羧甲基纤维素钠5-10份、甘草酸二钾6-10份、赤芍粉7-11份、冰片10-18份、甲基丙烯酸羟丙酯5-8份、维生素1-5份。
2.根据权利要求1所述的具有抗菌止血功效的防粘连膜，其特征在于：其还包含六偏磷酸钠1-4份。
3.根据权利要求2所述的具有抗菌止血功效的防粘连膜，其特征在于：其还包含马来酸酐2-6份。
4.根据权利要求3所述的具有抗菌止血功效的防粘连膜，其特征在于：其还包含卡波姆3-5份。
CN201610427575.0A 2016-06-15 2016-06-15 一种具有抗菌止血功效的防粘连膜 Withdrawn CN105999428A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610427575.0A CN105999428A (zh) 2016-06-15 2016-06-15 一种具有抗菌止血功效的防粘连膜

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610427575.0A CN105999428A (zh) 2016-06-15 2016-06-15 一种具有抗菌止血功效的防粘连膜

Publications (1)

Publication Number Publication Date
CN105999428A true CN105999428A (zh) 2016-10-12

Family

ID=57088473

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610427575.0A Withdrawn CN105999428A (zh) 2016-06-15 2016-06-15 一种具有抗菌止血功效的防粘连膜

Country Status (1)

Country Link
CN (1) CN105999428A (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108715676A (zh) * 2018-06-20 2018-10-30 安徽申科塑业有限公司 一种新型生物材料

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1898294A (zh) * 2003-12-18 2007-01-17 伊斯曼化学公司 具有改善的热性能的高透明性薄膜
CN101623517A (zh) * 2009-08-11 2010-01-13 广州迈普再生医学科技有限公司 一种医用防粘连膜及其制备方法
CN201888954U (zh) * 2010-07-12 2011-07-06 北京迈迪顶峰医疗科技有限公司 一种防粘连膜
CN105396180A (zh) * 2014-09-02 2016-03-16 上海微创医疗器械（集团）有限公司 一种生物可降解增塑剂、医用防粘连膜及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1898294A (zh) * 2003-12-18 2007-01-17 伊斯曼化学公司 具有改善的热性能的高透明性薄膜
CN101623517A (zh) * 2009-08-11 2010-01-13 广州迈普再生医学科技有限公司 一种医用防粘连膜及其制备方法
CN201888954U (zh) * 2010-07-12 2011-07-06 北京迈迪顶峰医疗科技有限公司 一种防粘连膜
CN105396180A (zh) * 2014-09-02 2016-03-16 上海微创医疗器械（集团）有限公司 一种生物可降解增塑剂、医用防粘连膜及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108715676A (zh) * 2018-06-20 2018-10-30 安徽申科塑业有限公司 一种新型生物材料

Similar Documents

Publication Publication Date Title
Xiao et al. Osteochondral repair using scaffolds with gradient pore sizes constructed with silk fibroin, chitosan, and nano-hydroxyapatite
Koivuniemi et al. Clinical study of nanofibrillar cellulose hydrogel dressing for skin graft donor site treatment
Pighinelli et al. Chitosan–hydroxyapatite composites
Brennan et al. Antibacterial activity within degradation products of biological scaffolds composed of extracellular matrix
Venugopal et al. Electrospun PCL nanofibers blended with Wattakaka volubilis active phytochemicals for bone and cartilage tissue engineering
CN101773689B (zh) 外科修复补片
CN104403170A (zh) 一种医用ldpe抗菌塑料及其制备方法
CN106075545A (zh) 一种具有抗菌止血功效的软组织用粘合剂
CN104448479A (zh) 一种医用抗菌剂改性ldpe及其制备方法
CN105999376A (zh) 一种具有镇痛抗菌功效的手术缝合线
CN105963759A (zh) 一种促进伤口愈合的医用薄膜
CN105999375A (zh) 一种具有镇痛抗菌功效的医用可吸收缝合线
CN105963802A (zh) 一种促进伤口愈合的防粘连膜
CN102618954B (zh) 一种人血清白蛋白纳米生物材料及其制备方法
CN105999428A (zh) 一种具有抗菌止血功效的防粘连膜
CN105963803A (zh) 一种具有镇痛抗菌功效的防粘连膜
CN106075611A (zh) 一种具有消炎抗菌功效的防粘连膜
CN105999379A (zh) 一种抗菌消炎的医用可吸收缝合线
CN102091057A (zh) 一种制备载药生物膜的方法
CN104448523A (zh) 一种医用eva薄膜及其制备方法
CN105999429A (zh) 一种可吸收的防粘连膜
CN106075531A (zh) 一种消肿止痛的医用薄膜
CN105963799A (zh) 一种抗感染的防粘连膜
CN105944136A (zh) 一种促进伤口愈合的医用可吸收缝合线
CN106039386A (zh) 一种抗感染的手术缝合线

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20161012