CN105999216A - Candied ephedra decoction pieces for eliminating cold to stop wheezing and preparation method thereof - Google Patents
Candied ephedra decoction pieces for eliminating cold to stop wheezing and preparation method thereof Download PDFInfo
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- CN105999216A CN105999216A CN201610531035.7A CN201610531035A CN105999216A CN 105999216 A CN105999216 A CN 105999216A CN 201610531035 A CN201610531035 A CN 201610531035A CN 105999216 A CN105999216 A CN 105999216A
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- herba ephedrae
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- wheezing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention discloses candied ephedra decoction pieces for eliminating cold to stop wheezing and a preparation method thereof. The decoction pieces are prepared from, by weight, 50-60 parts of ephedra, 13-15 parts of collagen powder, 13-15 parts of lentinan, 5-6 parts of cellulase, 70-80 parts of natural honey, 8-9 parts of apricot kernel oil, 10-12 parts of cassia twigs, 10-12 parts of schisandra chinensis, 20-23 parts of rice vinegar, 8-9 parts of honey-fried licorice roots, 8-9 parts of exocarpium citri rubrum and 10-12 parts of agastache rugosus leaves. The effective ingredients of the candied ephedra decoction pieces for eliminating cold to stop wheezing have the healthcare effects of eliminating cold to stop wheezing, enhancing immunity and the like.
Description
Technical field
The present invention relates to prepared slices of Chinese crude drugs technical field, particularly relate to a kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces and preparation method thereof.
Background technology
The prepared slices of Chinese crude drugs are under guidance of traditional Chinese medicine theory, and according to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs principle and the needs of formulation dispensing, the finished product that centering processing of crude drugs is concocted is tcm clinical practice medication, play dialectical plus-minus, embody the basis of personalized medicine principle.The prepared slices of Chinese crude drugs are one of big pillars of Chinese herbal medicine industry three
, the important component part of Ye Shi China traditional medicine, diseases prevention, cure the disease in play an important role.Therefore the quality of The Quality of Sliced Herbal Medicine will directly influence the effect of tcm clinical practice treatment, have influence on people's life's health and the safety of medication.
Cellulose is the regenerated resources that on the earth, quantity is maximum, be plant cell wall mainly comprise composition.At present, the cellulose major part in nature is not utilized, and causes the huge wasting of resources, even environmental pollution, and agricultural byproducts and industrial waste etc. that cellulase can will be enriched in cellulose effectively convert.Since within 1996, finding cellulase from the Digestive system of Limax, people have carried out substantial amounts of research to cellulose enzyme viability, mechanism of action and industrial applications thereof etc., production and application for cellulase are had laid a good foundation, especially for expanding raw materials for food industry and the comprehensive utilization of plant resources, improve raw material availability, environment purification and aspect tools such as opening up new forms of energy to be of great significance.
Enzyme immobilizatio is or to be limited to enzyme constraint in certain area with solid material, can still provide for its distinctive catalytic reaction, and a recyclable and reusable class technology.Compared with resolvase, immobilized enzyme is keeping while its efficient, single-minded and gentle enzymic catalytic reaction characteristic, also present that bin stability is high, separation and recovery easily, can repeatedly use, operate the series of advantages such as the most controlled, simple process.Enzyme immobilizatio and enzymatic reaction research thereof are one of biotechnology Disciplinary Frontiers most with prospects; it has important value to illustrating enzyme model of action, action rule and regulatory mechanism in vivo; having opened up wide prospect for enzyme preparation in the application of the aspects such as biological engineering, biomedicine, environmental conservation, it will play a significant role in human social strategy simultaneously.
Herba Ephedrae, nature and flavor with return through hardship pungent, micro-, temperature.Return lung, bladder warp.Function with cure mainly: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chest breath with cough, edema due to wind pathogen edema.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces.
The present invention is achieved by the following technical solutions:
A kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces, is made up of following raw materials in part by weight:
Herba Ephedrae 50-60, collagen protein powder 13-15, lentinan 13-15, cellulase 5-6, natural honey 70-80, almond oil 8-9, Ramulus Cinnamomi 10-12, Fructus Schisandrae Chinensis 10-12, rice vinegar 20-23, Radix Glycyrrhizae Preparata 8-9, Exocarpium Citri Rubrum 8-9, Radix agastaches 10-12.
Described a kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces, is made up of the following step:
1), Herba Ephedrae is cleaned, remove woody stems, undesirable root and impurity, clean Herba Ephedrae is loaded in Turnround basket, cleans end；
2), using HL-300 type mincing type medicine cutter, it is 5-10mm section that web degree is cut in regulation, is put by Herba Ephedrae neatly, spreads real pressing thickness 8-10mm, and the Herba Ephedrae after cutting loads in Turnover Box；
3), by Ramulus Cinnamomi, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata, Exocarpium Citri Rubrum, Radix agastaches, rice vinegar mixing, add 20-25 times amount water, slow fire infusion 3-5 hour, make decoction be concentrated into the 1/5-3 of stock solution, filtering and impurity removing, collect filtrate；
4), step 3 gained filtering residue is rubbed, add 5-10 times amount decocting in water to boiling, stop heating, being cooled to 60-70 DEG C, regulation pH value, in 4.0-6.0, is subsequently adding the agar immobilized cellulase granule that mass fraction is 5-10%, in 55-60 DEG C of ferment at constant temperature 3-5 hour, filter, separate and recover immobilized cellulase, collect filtrate；
5), natural honey is put in inclinable jacketed kettle, mix with step 3, step 4 gained filtrate, after being heated to slowly seething with excitement, use slow fire instead, keeping the waxiness of micro-boiling, scumming and floating and dead honeybee, temperature is maintained at 116-118 DEG C, refining to panful plays fish bubble eye, adding collagen protein powder, lentinan, almond oil, mixing, with the toughness of hands sth. made by twisting, there is no white silk between finger when occurring, take the dish out of the pot rapidly；
6), take step 5 gained mixture and step 2 gained Herba Ephedrae sheet and mix vexed 30-40 minute, be then placed in hot pot, stir rapidly, fry to surface color with slow fire and deepen, tack-free take out constantly, airing；
7), surface buff is selected, micro-glossy, somewhat stickiness, there is sweet fragrance, the Herba ephedrae that taste is sweet, remove and stick with paste sheet fragment, pack with non-toxic polyethylene plastic, transparent bag, seal up for safekeeping.
The invention have the advantage that
1, a kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces of the present invention, after fully being extracted by Chinese medicine, extracting solution is used as medicine, and its residue is carried out enzymolysis, makes residue be fully used.
2, compared with resolvase, immobilized enzyme is keeping while its efficient, single-minded and gentle enzymic catalytic reaction characteristic, also present that bin stability is high, separation and recovery easily, can repeatedly use, operate the advantages such as the most controlled, simple process.
3, a kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces of the present invention, contained effective ingredient have cold expelling, relieving asthma, strengthen immunity etc. health-care effect.
Detailed description of the invention
A kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces, is made up of following raw materials in part by weight:
Herba Ephedrae 50, collagen protein powder 13, lentinan 13, cellulase 5, natural honey 70, almond oil 8, Ramulus Cinnamomi 10, Fructus Schisandrae Chinensis 10, rice vinegar 20, Radix Glycyrrhizae Preparata 8, Exocarpium Citri Rubrum 8, Radix agastaches 10.
Described a kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces, is made up of the following step:
1), Herba Ephedrae is cleaned, remove woody stems, undesirable root and impurity, clean Herba Ephedrae is loaded in Turnround basket, cleans end；
2), using HL type mincing type medicine cutter, it is 5mm section that web degree is cut in regulation, is put by Herba Ephedrae neatly, spreads real pressing thickness 10mm, and the Herba Ephedrae after cutting loads in Turnover Box；
3), by Ramulus Cinnamomi, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata, Exocarpium Citri Rubrum, Radix agastaches, rice vinegar mixing, add 20 times amount water, slow fire infusion 3 hours, make decoction be concentrated into the 1/3 of stock solution, filtering and impurity removing, collect filtrate；
4), step 3 gained filtering residue is rubbed, add 5 times amount decocting in water to boiling, stop heating, being cooled to 60 DEG C, regulation pH value, in 5.0, is subsequently adding the agar immobilized cellulase granule that mass fraction is 5%, in 55 DEG C of ferment at constant temperature 3 hours, filter, separate and recover immobilized cellulase, collect filtrate；
5), natural honey is put in inclinable jacketed kettle, mix with step 3, step 4 gained filtrate, after being heated to slowly seething with excitement, use slow fire instead, keeping the waxiness of micro-boiling, scumming and floating and dead honeybee, temperature is maintained at 116 DEG C, refining to panful plays fish bubble eye, adding collagen protein powder, lentinan, almond oil, mixing, with the toughness of hands sth. made by twisting, there is no white silk between finger when occurring, take the dish out of the pot rapidly；
6), take step 5 gained mixture and step 2 gained Herba Ephedrae sheet and mix vexed 30 minutes, be then placed in hot pot, stir rapidly, fry to surface color with slow fire and deepen, tack-free take out constantly, airing；
7), surface buff is selected, micro-glossy, somewhat stickiness, there is sweet fragrance, the Herba ephedrae that taste is sweet, remove and stick with paste sheet fragment, pack with non-toxic polyethylene plastic, transparent bag, seal up for safekeeping.
Claims (2)
1. an expelling cold for relieving asthma candied Herba Ephedrae decoction pieces, it is characterised in that be made up of following raw materials in part by weight:
Herba Ephedrae 50-60, collagen protein powder 13-15, lentinan 13-15, cellulase 5-6, natural honey 70-80, almond oil 8-9, Ramulus Cinnamomi 10-12, Fructus Schisandrae Chinensis 10-12, rice vinegar 20-23, Radix Glycyrrhizae Preparata 8-9, Exocarpium Citri Rubrum 8-9, Radix agastaches 10-12.
A kind of expelling cold for relieving asthma candied Herba Ephedrae decoction pieces the most according to claim 1, it is characterised in that be made up of the following step:
1), Herba Ephedrae is cleaned, remove woody stems, undesirable root and impurity, clean Herba Ephedrae is loaded in Turnround basket, cleans end；
2), using HL-300 type mincing type medicine cutter, it is 5-10mm section that web degree is cut in regulation, is put by Herba Ephedrae neatly, spreads real pressing thickness 8-10mm, and the Herba Ephedrae after cutting loads in Turnover Box；
3), by Ramulus Cinnamomi, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata, Exocarpium Citri Rubrum, Radix agastaches, rice vinegar mixing, add 20-25 times amount water, slow fire infusion 3-5 hour, make decoction be concentrated into the 1/5-3 of stock solution, filtering and impurity removing, collect filtrate；
4), step 3 gained filtering residue is rubbed, add 5-10 times amount decocting in water to boiling, stop heating, being cooled to 60-70 DEG C, regulation pH value, in 4.0-6.0, is subsequently adding the agar immobilized cellulase granule that mass fraction is 5-10%, in 55-60 DEG C of ferment at constant temperature 3-5 hour, filter, separate and recover immobilized cellulase, collect filtrate；
5), natural honey is put in inclinable jacketed kettle, mix with step 3, step 4 gained filtrate, after being heated to slowly seething with excitement, use slow fire instead, keeping the waxiness of micro-boiling, scumming and floating and dead honeybee, temperature is maintained at 116-118 DEG C, refining to panful plays fish bubble eye, adding collagen protein powder, lentinan, almond oil, mixing, with the toughness of hands sth. made by twisting, there is no white silk between finger when occurring, take the dish out of the pot rapidly；
6), take step 5 gained mixture and step 2 gained Herba Ephedrae sheet and mix vexed 30-40 minute, be then placed in hot pot, stir rapidly, fry to surface color with slow fire and deepen, tack-free take out constantly, airing；
7), surface buff is selected, micro-glossy, somewhat stickiness, there is sweet fragrance, the Herba ephedrae that taste is sweet, remove and stick with paste sheet fragment, pack with non-toxic polyethylene plastic, transparent bag, seal up for safekeeping.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610531035.7A CN105999216A (en) | 2016-07-07 | 2016-07-07 | Candied ephedra decoction pieces for eliminating cold to stop wheezing and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610531035.7A CN105999216A (en) | 2016-07-07 | 2016-07-07 | Candied ephedra decoction pieces for eliminating cold to stop wheezing and preparation method thereof |
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| CN105999216A true CN105999216A (en) | 2016-10-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610531035.7A Pending CN105999216A (en) | 2016-07-07 | 2016-07-07 | Candied ephedra decoction pieces for eliminating cold to stop wheezing and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110193032A (en) * | 2019-06-26 | 2019-09-03 | 甘肃省和顺元中药饮片有限公司 | A kind of concocting method of Chinese ephedra medicine materical crude slice |
| CN112715897A (en) * | 2019-10-14 | 2021-04-30 | 江西巨荣生物科技有限公司 | Solidified enzyme honey and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1262115A (en) * | 1999-02-04 | 2000-08-09 | 李玉海 | Medical mixture for treating baby asthma and cough |
| CN102178779A (en) * | 2011-04-25 | 2011-09-14 | 悦康药业集团有限公司 | Method for preparing capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome and application |
| CN102764414A (en) * | 2011-05-05 | 2012-11-07 | 北京亚东生物制药有限公司 | Method for preparing Xiaoqinglong mixture |
| CN105288157A (en) * | 2015-11-17 | 2016-02-03 | 谢暕 | Traditional Chinese medicine composition with effects of freeing lung and relieving asthma, preparation method and application thereof |
-
2016
- 2016-07-07 CN CN201610531035.7A patent/CN105999216A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1262115A (en) * | 1999-02-04 | 2000-08-09 | 李玉海 | Medical mixture for treating baby asthma and cough |
| CN102178779A (en) * | 2011-04-25 | 2011-09-14 | 悦康药业集团有限公司 | Method for preparing capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome and application |
| CN102764414A (en) * | 2011-05-05 | 2012-11-07 | 北京亚东生物制药有限公司 | Method for preparing Xiaoqinglong mixture |
| CN105288157A (en) * | 2015-11-17 | 2016-02-03 | 谢暕 | Traditional Chinese medicine composition with effects of freeing lung and relieving asthma, preparation method and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110193032A (en) * | 2019-06-26 | 2019-09-03 | 甘肃省和顺元中药饮片有限公司 | A kind of concocting method of Chinese ephedra medicine materical crude slice |
| CN112715897A (en) * | 2019-10-14 | 2021-04-30 | 江西巨荣生物科技有限公司 | Solidified enzyme honey and preparation method thereof |
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Application publication date: 20161012 |
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