CN105288157A - Traditional Chinese medicine composition with effects of freeing lung and relieving asthma, preparation method and application thereof - Google Patents
Traditional Chinese medicine composition with effects of freeing lung and relieving asthma, preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition with effects of freeing lung and relieving asthma, a preparation method and an application thereof, and belongs to the technical field of Chinese herbal medicine. Active ingredients of the traditional Chinese medicine composition are prepared from the following raw materials: radix astragali, polygonatum odoratum, Radix Ophiopogonis, root of kudzu vine, honey-fried licorice root, Chinese yam, exocarpium citrus grandis, white Poria cocos, lotus seed, peach kernel, bitter apricot kernel, Chinese magnoliavine and folium eriobotryae. The traditional Chinese medicine composition of the invention can achieve effects of fundamentally regulating lung Qi, enhancing the lung's ability of resisting external disoperation and freeing lung and relieving asthma. In addition, chronic cough is not easy to recur after use of the traditional Chinese medicine composition. Even infected with cold, the caused cough also will be cured rapidly.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of there is depressed lung-energy dispersing effect Chinese medicine composition, preparation method and application thereof.
Background technology
The disease that cough is a kind of broad covered area, harm is larger, its cause of disease has multiple, and the cough disease time caused by the deficiency of the lung the longest and comparatively stubbornness not easily eradicate, obstinate severe patient also can cause the diseases such as pulmonary tuberculosis, emphysema, pulmonary heart disease, consumptive lung disease, pulmonary atelectasis.The traditional Chinese medical science it seems that the deficiency of the lung comprises the deficiency of YIN and the deficiency of vital energy, and deficiency of lung-YIN person is many because of body fluid consumption, and lung mistake profit is usually expressed as shape thin thin and weak, dry cough without phlegm caused by supporting, or the few matter of expectorant sticks, or coughs and sputum mixed with blood silk; Insufficiency of lung-QI person mostly is prolonged illness loss, and vigour is multiple after being ill, or feels frustrated because of chronic cough, so that lung qi virtual loss, and show as and cough and breathe hard, cough with asthma is unable, and chronic cough is not healed, clear and thin sputum; Tiredness with no desire to speak, sound is low timid, and complexion is turned white, anemophobia cold physique.Deficiency of the lung patient susceptible wind and cold and very easily cause permanent cough, the coldrex treatment not significant curative effect that the cough caused by the deficiency of the lung is general, basic reason is that coldrex does not fundamentally nurse one's health foster lung, and the commercially available Drug therapy with relieving cough and resolving phlegm effect slowly and fundamentally can not improve deficiency of the lung symptom, easily recur.
Summary of the invention
For solving the defect that prior art exists, the present invention aim to provide a kind of evident in efficacy, have no side effect, treat after the Chinese medicine composition with depressed lung-energy dispersing effect that not easily recurs, also comprise its preparation method and application.
To achieve these goals, technical scheme of the present invention is:
Have a Chinese medicine composition for depressed lung-energy dispersing effect, its effective ingredient is made up of the raw material of following weight portion: Radix Astragali 60-80 part, Rhizoma Polygonati Odorati 40-80 part, Radix Ophiopogonis 40-80 part, Radix Puerariae 50-80 part, Radix Glycyrrhizae Preparata 50-80 part, Rhizoma Dioscoreae 40-60 part, Exocarpium Citri Grandis 50-80 part, Poria 70-90 part, Semen Nelumbinis 10-20 part, Semen Persicae 30-60 part, Semen Armeniacae Amarum 40-80 part, Fructus Schisandrae Chinensis 40-60 part, Folium Eriobotryae 80-100 part; Described effective ingredient adopts following method to prepare: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, Exocarpium Citri Grandis water extraction 2-4 time of 5-10 times of weight, each 2-4 hour, under 40-60 DEG C of condition, be evaporated to the 1/3-1/4 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add water extraction 2-4 time of 5-8 times of weight, each 2-3 hour, is evaporated to the 1/3-1/4 of former filtrate volume, obtains concentrated solution C under 40-60 DEG C of condition after merging each filtrate of extracting; Merge B, C and be dried to powder under 50-60 DEG C of condition, obtain fine powder D; Merge fine powder A and D, to obtain final product.
The present invention also comprises following additional technical feature:
Preferably, the raw material of described weight portion is: the Radix Astragali 70 parts, Rhizoma Polygonati Odorati 60 parts, Radix Ophiopogonis 60 parts, Radix Puerariae 60 parts, Radix Glycyrrhizae Preparata 60 parts, Rhizoma Dioscoreae 50 parts, Exocarpium Citri Grandis 60 parts, Poria 80 parts, 15 parts, Semen Nelumbinis, 45 parts, Semen Persicae, Semen Armeniacae Amarum 60 parts, Fructus Schisandrae Chinensis 50 parts, Folium Eriobotryae 90 parts.
Preferably, described effective ingredient adopts following method to prepare: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 3 times of 8 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/4 of former filtrate volume after merging the filtrate of each extraction, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, adds the water extraction 3 times of 6 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/3 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C; Merge B, C and be dried to powder under 50 DEG C of conditions, obtain fine powder D; Merge fine powder A and D, to obtain final product.
Preferably, the dosage form of described Chinese medicine composition is tablet, granule, capsule or oral liquid.
Preferably, it is characterized in that, described Chinese medicine composition is also containing the acceptable adjuvant of pharmaceutics.
Preferably, described acceptable adjuvant comprises at least one in dextrin, starch, Mel, sucrose, glucose, microcrystalline Cellulose, carboxymethyl cellulose, magnesium stearate, crospolyvinylpyrrolidone, polyvinyl alcohol, hydroxy methocel, methylcellulose.
The present invention also comprises the above-mentioned preparation method with the Chinese medicine composition of depressed lung-energy dispersing effect, comprises the following steps: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, Exocarpium Citri Grandis water extraction 2-4 time of 5-10 times of weight, each 2-4 hour, under 40-60 DEG C of condition, be evaporated to the 1/3-1/4 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add water extraction 2-4 time of 5-8 times of weight, each 2-3 hour, is evaporated to the 1/3-1/4 of former filtrate volume, obtains concentrated solution C under 40-60 DEG C of condition after merging each filtrate of extracting; Merge B, C and be dried to powder under 50-60 DEG C of condition, obtain fine powder D; Merge fine powder A and D, to obtain final product.
Preferably, described step is: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 3 times of 8 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/4 of former filtrate volume after merging the filtrate of each extraction, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, adds the water extraction 3 times of 6 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/3 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C; Merge B, C and be dried to powder under 50 DEG C of conditions, obtain fine powder D; Merge fine powder A and D, to obtain final product.
The present invention also comprises above-mentioned Chinese medicine composition and is preparing the application had in the medicine of depressed lung-energy dispersing effect.
Beneficial effect of the present invention is:
1) effect for the treatment of both the principal and secondary aspects of a disease is played in the cough that Chinese medicine composition of the present invention can cause for the deficiency of the lung, lung is " tender dirty ", very tender and lovely, but because the external world directly communicates, the strength of opposing pathogenic factor is weaker, easy generation pathological changes, Chinese medicine composition of the present invention can fundamentally Tiao Chang pulmonary mechanism of qi, strengthen the ability of the extraneous infringement of pulmonary's opposing, reach the effect of depressed lung-energy dispersing, and not easily again occur the cureless phenomenon of cough, even if infect wind and cold, caused cough also can comparatively fast be cured.
2) the present invention is Chinese patent medicine preparation, without chemical composition and additive, to human non-toxic's side effect, more meets natural, healthy consumption demand;
Additional aspect of the present invention and advantage will part provide in the following description, and part will become obvious from the following description, or be recognized by practice of the present invention.
Detailed description of the invention
Below in conjunction with instantiation, the present invention is described in detail.
Embodiment 1
A. the raw material of following weight portion is taken:
Radix Astragali 7kg, Rhizoma Polygonati Odorati 6kg, Radix Ophiopogonis 6kg, Radix Puerariae 6kg, Radix Glycyrrhizae Preparata 6kg, Rhizoma Dioscoreae 5kg, Exocarpium Citri Grandis 6kg, Poria 8kg, Semen Nelumbinis 1.5kg, Semen Persicae 4.5kg, Semen Armeniacae Amarum 6kg, Fructus Schisandrae Chinensis 5kg, Folium Eriobotryae 9kg;
B. following steps are adopted to prepare effective ingredient:
1. Poria, Rhizoma Dioscoreae being milled to powder, is fine powder A;
2. by the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 3 times of 8 times of weight, each 2.5 hours, be evaporated to 1/4 of former filtrate volume after merging the filtrate of each extraction under 50 DEG C of conditions, obtain concentrated solution B;
3. Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add the water extraction 3 times of 6 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/3 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C;
4. merge B, C and be dried to powder under 50 DEG C of conditions, obtain fine powder D;
5. merge fine powder A and D, to obtain final product.
Embodiment 2
A. the raw material of following weight portion is taken:
Radix Astragali 6kg, Rhizoma Polygonati Odorati 4kg, Radix Ophiopogonis 4kg, Radix Puerariae 5kg, Radix Glycyrrhizae Preparata 5kg, Rhizoma Dioscoreae 4kg, Exocarpium Citri Grandis 5kg, Poria 7kg, Semen Nelumbinis 1kg, Semen Persicae 3kg, Semen Armeniacae Amarum 4kg, Fructus Schisandrae Chinensis 4kg, Folium Eriobotryae 8kg;
B. following steps are adopted to prepare effective ingredient:
1. Poria, Rhizoma Dioscoreae being milled to powder, is fine powder A;
2. by the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 2 times of 7 times of weight, each 2 hours, be evaporated to 1/3 of former filtrate volume after merging the filtrate of each extraction under 60 DEG C of conditions, obtain concentrated solution B;
3. Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add the water extraction 4 times of 8 times of weight, each 3 hours, under 60 DEG C of conditions, be evaporated to 1/4 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C;
4. merge B, C and be dried to powder under 60 DEG C of conditions, obtain fine powder D;
5. merge fine powder A and D, to obtain final product.
Embodiment 3
A. the raw material of following weight portion is taken:
Radix Astragali 8kg, Rhizoma Polygonati Odorati 6kg, Radix Ophiopogonis 8kg, Radix Puerariae 7kg, Radix Glycyrrhizae Preparata 8kg, Rhizoma Dioscoreae 6kg, Exocarpium Citri Grandis 8kg, Poria 9kg, Semen Nelumbinis 2kg, Semen Persicae 6kg, Semen Armeniacae Amarum 8kg, Fructus Schisandrae Chinensis 6kg, Folium Eriobotryae 10kg;
B. following steps are adopted to prepare effective ingredient:
1. Poria, Rhizoma Dioscoreae being milled to powder, is fine powder A;
2. by the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 4 times of 8 times of weight, each 4 hours, be evaporated to 1/4 of former filtrate volume after merging the filtrate of each extraction under 60 DEG C of conditions, obtain concentrated solution B;
3. Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add the water extraction 3 times of 8 times of weight, each 3 hours, under 50 DEG C of conditions, be evaporated to 1/3 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C;
4. merge B, C and be dried to powder under 50-60 DEG C of condition, obtain fine powder D;
5. merge fine powder A and D, to obtain final product.
Embodiment 4 prepares oral liquid
Effective ingredient 500g obtained in Example 1, adds in 1500g Mel, obtained oral liquid of the present invention.
Embodiment 5 prepares tablet
Effective ingredient 500g obtained in Example 1, adds 50g microcrystalline Cellulose, 30g starch, 30g sodium carboxymethyl cellulose, tabletted, the heavy 0.25g of every sheet.
Embodiment 6 prepares capsule
Effective ingredient 500g obtained in Example 1, adds corn starch 80g, magnesium stearate 50g, records capsule, the heavy 0.4g of every capsules.
Embodiment 7
1) toxicity research
Choose 50 healthy rats, male and female half and half, body weight is 200 ± 10g, the oral liquid of gavage 1g embodiment 4 in one day, 70 times that are equivalent to that the adult of 70Kg daily measures according to the dose of adult (60-80kg) 5g every day, Continuous Observation one week, rat has no adverse reaction, health is good, and this product safety and low toxicity are described.
2) clinical efficacy
The clinical manifestation of deficiency of the lung patient is that cough with asthma is breathed hard, and sound is low timid, spontaneous perspiration with aversion to wind, susceptible exopathogen, shortness of breath and fatigue, pallor Mental fatigue, pale tongue with white fur, weak pulse.The cough with asthma patient that clinical observation 100 example causes because of the deficiency of the lung, wherein man 41, female 59, age distribution be 20-70 year, use oral liquid obtained in embodiment 4, using method and consumption are one day twice, and each 2.5g divides into groups according to the course of disease, namely the cough state of an illness certainly caused by catching a cold first was more than 10 days, and can determine that the cough that the deficiency of the lung causes is started at, carry out statistical effect to it after taking 30 days and continue tracking 1 year observing patient and coughing situation, effect determining method is as follows:
Cure: clinical symptom disappearance, even and if infected wind and cold in 1 year, the symptom of cough also can disappear in one week.
Effective: clinical symptoms is clearly better, even and if infect wind and cold in 1 year, before the symptom of cough also can comparatively take medicament, healing period obviously accelerates.
Invalid: clinical symptoms is without improvement.
Therapeutic effect statistics is in table 1:
Table 1 oral liquid of the present invention is to the therapeutic effect statistical table of cough due to deficiency of the lung
In clinical treatment, patient is after suffering from the cold cough that the deficiency of the lung causes, and take the oral liquid 2 days of the present embodiment 4, cough symptom starts to alleviate, and deficiency of the lung sense fades away during cough, be clearly better after 5 days, spontaneous perspiration, weak minimizing, voice gas foot, effectively loud and clear, a week can cure completely.
Although illustrate and describe embodiments of the invention, those having ordinary skill in the art will appreciate that: can carry out multiple change, amendment, replacement and modification to these embodiments when not departing from principle of the present invention and aim, scope of the present invention is by claim and equivalents thereof.
Claims (9)
1. one kind has the Chinese medicine composition of depressed lung-energy dispersing effect, it is characterized in that, its effective ingredient is made up of the raw material of following weight portion: Radix Astragali 60-80 part, Rhizoma Polygonati Odorati 40-80 part, Radix Ophiopogonis 40-80 part, Radix Puerariae 50-80 part, Radix Glycyrrhizae Preparata 50-80 part, Rhizoma Dioscoreae 40-60 part, Exocarpium Citri Grandis 50-80 part, Poria 70-90 part, Semen Nelumbinis 10-20 part, Semen Persicae 30-60 part, Semen Armeniacae Amarum 40-80 part, Fructus Schisandrae Chinensis 40-60 part, Folium Eriobotryae 80-100 part; Described effective ingredient adopts following method to prepare: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, Exocarpium Citri Grandis water extraction 2-4 time of 5-10 times of weight, each 2-4 hour, under 40-60 DEG C of condition, be evaporated to the 1/3-1/4 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add water extraction 2-4 time of 5-8 times of weight, each 2-3 hour, is evaporated to the 1/3-1/4 of former filtrate volume, obtains concentrated solution C under 40-60 DEG C of condition after merging each filtrate of extracting; Merge B, C and be dried to powder under 50-60 DEG C of condition, obtain fine powder D; Merge fine powder A and D, to obtain final product.
2. a kind of Chinese medicine composition with depressed lung-energy dispersing effect according to claim 1, it is characterized in that, the raw material of described weight portion is: the Radix Astragali 70 parts, Rhizoma Polygonati Odorati 60 parts, Radix Ophiopogonis 60 parts, Radix Puerariae 60 parts, Radix Glycyrrhizae Preparata 60 parts, Rhizoma Dioscoreae 50 parts, Exocarpium Citri Grandis 60 parts, Poria 80 parts, 15 parts, Semen Nelumbinis, 45 parts, Semen Persicae, Semen Armeniacae Amarum 60 parts, Fructus Schisandrae Chinensis 50 parts, Folium Eriobotryae 90 parts.
3. a kind of Chinese medicine composition with depressed lung-energy dispersing effect according to claim 1, is characterized in that, described effective ingredient adopts following method to prepare: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 3 times of 8 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/4 of former filtrate volume after merging the filtrate of each extraction, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, adds the water extraction 3 times of 6 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/3 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C; Merge B, C and be dried to powder under 50 DEG C of conditions, obtain fine powder D; Merge fine powder A and D, to obtain final product.
4. a kind of Chinese medicine composition with depressed lung-energy dispersing effect according to any one of claim 1-3, is characterized in that, the dosage form of described Chinese medicine composition is tablet, granule, capsule or oral liquid.
5. a kind of Chinese medicine composition with depressed lung-energy dispersing effect according to any one of claim 1-3, is characterized in that, described Chinese medicine composition is also containing the acceptable adjuvant of pharmaceutics.
6. a kind of Chinese medicine composition with depressed lung-energy dispersing effect according to claim 5, it is characterized in that, described acceptable adjuvant comprises at least one in dextrin, starch, Mel, sucrose, glucose, microcrystalline Cellulose, carboxymethyl cellulose, magnesium stearate, crospolyvinylpyrrolidone, polyvinyl alcohol, hydroxy methocel, methylcellulose.
7. a kind of preparation method with the Chinese medicine composition of depressed lung-energy dispersing effect described in claim 1, is characterized in that, comprise the following steps: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, Exocarpium Citri Grandis water extraction 2-4 time of 5-10 times of weight, each 2-4 hour, under 40-60 DEG C of condition, be evaporated to the 1/3-1/4 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, add water extraction 2-4 time of 5-8 times of weight, each 2-3 hour, is evaporated to the 1/3-1/4 of former filtrate volume, obtains concentrated solution C under 40-60 DEG C of condition after merging each filtrate of extracting; Merge B, C and be dried to powder under 50-60 DEG C of condition, obtain fine powder D; Merge fine powder A and D, to obtain final product.
8. a kind of preparation method with the Chinese medicine composition of depressed lung-energy dispersing effect according to claim 7, it is characterized in that, described step is: take each raw material by proportioning raw materials; Poria, Rhizoma Dioscoreae are milled to powder, are fine powder A; By the Radix Astragali, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Radix Puerariae, Radix Glycyrrhizae Preparata, batch leaf, the Exocarpium Citri Grandis water extraction 3 times of 8 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/4 of former filtrate volume after merging the filtrate of each extraction, obtain concentrated solution B; Semen Nelumbinis, Semen Persicae, Semen Armeniacae Amarum are mixed with Fructus Schisandrae Chinensis after being milled to powder, adds the water extraction 3 times of 6 times of weight, each 2.5 hours, under 50 DEG C of conditions, be evaporated to 1/3 of former filtrate volume after merging each filtrate of extracting, obtain concentrated solution C; Merge B, C and be dried to powder under 50 DEG C of conditions, obtain fine powder D; Merge fine powder A and D, to obtain final product.
9. the Chinese medicine composition according to any one of claim 1-6 is preparing the application had in the medicine of depressed lung-energy dispersing effect.
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CN105999216A (en) * | 2016-07-07 | 2016-10-12 | 安徽精诚本草中药饮片有限公司 | Candied ephedra decoction pieces for eliminating cold to stop wheezing and preparation method thereof |
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