CN105998403A

CN105998403A - Traditional Chinese medicine used in cooperation with acupuncture therapy for treating sciatica and preparation method thereof

Info

Publication number: CN105998403A
Application number: CN201610453885.XA
Authority: CN
Inventors: 宋云; 张燕蕾; 游浩为; 杨明道
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-06-21
Filing date: 2016-06-21
Publication date: 2016-10-12

Abstract

The invention provides a traditional Chinese medicine used in cooperation with acupuncture therapy for treating sciatica and a preparation method thereof. The traditional Chinese medicine is prepared from creeping fig roots, pittosporum tobira trees, common exbucklandia stems, maire joint-pinna fern rhizome, mysorethorn, hygrophila salicifolia, Asarum wulingense C.F.Liang, Viola delavayi Franch., Balanophora polyandra, the root of shrubby elsholtzia, Tinomiscium, cleavers and shortwoolled goldsaxifrage. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicine can be used in cooperation with acupuncture therapy for treating sciatica, is good in treating effect, improves the acupuncture therapy treatment effect, and has no toxic or side effects and adverse reaction.

Description

A kind of Chinese medicine of combination acupuncture and moxibustion therapy sciatica and preparation method thereof

Technical field

The present invention relates to containing deriving from plant, animal or the medicinal preparation of raw mineral materials medical material, especially Relate to Chinese medicine of a kind of combination acupuncture and moxibustion therapy sciatica and preparation method thereof.

Background technology

Sciatica (sciatica) refers to the pain syndrome of sciatic nerve path machine areal area, Pain is positioned at outside on rear side of buttocks, thigh, after shank and outside foot.Sciatica is divided into former by the cause of disease The property sent out and Secondary cases, the former is sciatic neuritis, the most rare, often relevant with In vivo infection；Continue Send out property the modal cause of disease of sciatica be prolapse of lumbar intervertebral disc, spinal canal stenosis, also tumor, tuberculosis, Gravid uterus compressing, arachnoiditis etc..Primary disease is apt to occur in male adults, and physical labourer sickness rate is high, It mostly is unilateral.Onset is the most hurried, and minority is slow onset.Secondary Sciatic Pain presses diseased region It is divided into root and perception sciatica.

Sciatica belongs to " arthromyodynia " category of Chinese medicine, clinically press that wind and cold is wet more, insensitive impediment and The opinion such as muscular rheumatism is controlled.

Summary of the invention

The technical problem to be solved is, it is provided that a kind of combination acupuncture and moxibustion therapy sciatica Chinese medicine and preparation method thereof, its Chinese medicine uses plant amedica to combine with animal drugs, has rapid-action, drug effect Definitely, toxic and side effects is low.

In order to solve above-mentioned technical problem, the invention provides a kind of combination acupuncture and moxibustion therapy sciatica Chinese medicine, including following raw medicinal material: Radix Fici pumilae, pittosporum tobira tree, Caulis Exbucklandiae Populneae, Rhizoma Arthromeritis mairei, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang, Hygrophila salicifolia, Herba seu Radix Metaplexis hemsleyanae, step on wing medicine, Cor Gigeriae Galli seven, Os Gallus domesticus bavin, Tinomiscium petiolare Hook. f. et Thoms, Galium spurium L. and Chrysosplenium lanuginosum Hook. F. Et Thoms.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Radix Fici pumilae 10～20 parts, pittosporum tobira tree 20～45 parts, Caulis Exbucklandiae Populneae 5～20 parts, Rhizoma Arthromeritis mairei 15～30 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 20～30 parts, water Straw rain cape 5～20 parts, Herba seu Radix Metaplexis hemsleyanae 15～25 parts, step on wing medicine 5～15 parts, Cor Gigeriae Galli 7 15～25 parts, chicken Bone bavin 20～40 parts, Tinomiscium petiolare Hook. f. et Thoms 10～20 parts, Galium spurium L. 20～35 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 15～25 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material can also be as follows: Radix Fici pumilae 15～20 parts, sea Tung oil tree 25～30 parts, Caulis Exbucklandiae Populneae 7～15 parts, Rhizoma Arthromeritis mairei 15～25 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 20～28 Part, Hygrophila salicifolia 15～20 parts, Herba seu Radix Metaplexis hemsleyanae 18～25 parts, step on wing medicine 10～15 parts, Cor Gigeriae Galli 7 18～ 25 parts, Os Gallus domesticus bavin 25～33 parts, Tinomiscium petiolare Hook. f. et Thoms 15～20 parts, Galium spurium L. 25～35 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 20～25 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Radix Fici pumilae 16 parts, pittosporum tobira tree 28 parts, Caulis Exbucklandiae Populneae 7 parts, Rhizoma Arthromeritis mairei 15 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 26 parts, Hygrophila salicifolia 15 parts, falls to insert Spend 21 parts, step on wing medicine 12 parts, Cor Gigeriae Galli 7 20 parts, Os Gallus domesticus bavin 25 parts, Tinomiscium petiolare Hook. f. et Thoms 16 parts, Galium spurium L. 28 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 21 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Radix Fici pumilae 20 parts, pittosporum tobira tree 25 parts, Caulis Exbucklandiae Populneae 10 parts, Rhizoma Arthromeritis mairei 18 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 22 parts, Hygrophila salicifolia 19 parts, falls to insert Spend 25 parts, step on wing medicine 15 parts, Cor Gigeriae Galli 7 25 parts, Os Gallus domesticus bavin 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts, Galium spurium L. 35 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 25 parts.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is tablet, its system Preparation Method comprises the following steps,

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, the micropowders obtained by second step, add relative to its quality 0.1～0.3 times is micro- Crystalline cellulose, 0.05～0.15 times of lactose, starch of 0.1～0.3 times, sieve, mix homogeneously, pelletizes, It is dried, adds relative to micropowders quality 0.005～0.05 times of magnesium stearate, granulate, tabletting, system Become.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is oral liquid, Its preparation method comprises the following steps,

The first step, by Radix Fici pumilae, pittosporum tobira tree, Caulis Exbucklandiae Populneae, Rhizoma Arthromeritis mairei, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang and Hygrophila salicifolia are pressed Ratio mixes, and adds relative to 3 times of mixture～alcohol reflux that 5 times amount determining alcohols are 55%～65% 2 times～4 times, each 2 hours～3 hours, to filter, filtrate merges, and reclaims ethanol, is concentrated into 70 DEG C Relative density is the mastic of 1.30～1.32, standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 3～5 times amount water, boils Boil 2～4 hours, filter, be concentrated into the mastic that 70 DEG C of relative densities are 1.27～1.29；

3rd step, the described mastic mixing that the first step, second step are obtained, 55 DEG C～65 DEG C of reduced vacuum Being dried, get dry extract powder；

4th step, added ethanol in the described dried cream powder the 3rd step obtained, obtains containing alcohol mastic, described The alcohol content of containing alcohol mastic is 65%～70%；Described containing alcohol mastic is carried out chilling treatment, precipitation successively Process, filtration treatment, recovery Ethanol Treatment, obtain dealcoholysis mastic, wherein, the chilling treatment time be 30～ 40 hours, refrigerated storage temperature 1 DEG C～4 DEG C；

5th step, will in described dealcoholysis mastic add cane sugar powder, activated carbon, carry out successively heat treated, Filtration treatment, dilution process, and obtain semi-finished product；Described dealcoholysis mastic with the weight ratio of described cane sugar powder is 1: 0.1～0.3；Described dealcoholysis mastic is 1: 0.001～0.002 with the weight ratio of described activated carbon；Institute The time stating heat treated is 20～40 minutes, and temperature is 100 DEG C～110 DEG C；

6th step, then by the 5th step obtain described semi-finished product carry out successively filtration treatment, embedding process, Sterilization treatment, obtains described Chinese medicine oral liquid finished product.

Beneficial effects of the present invention: the present invention provide Chinese medicine can associating acupuncture and moxibustion therapy sciatica, Therapeutic effect is good, improves the therapeutic effect of acupuncture, has no side effect and untoward reaction.

Detailed description of the invention

Embodiments providing the Chinese medicine of a kind of combination acupuncture and moxibustion therapy sciatica, it includes Caulis fici pumilae (Fructus Fici Pumilae) Root, pittosporum tobira tree, Caulis Exbucklandiae Populneae, Rhizoma Arthromeritis mairei, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang, Hygrophila salicifolia, Herba seu Radix Metaplexis hemsleyanae, step on wing medicine, chicken The heart seven, Os Gallus domesticus bavin, Tinomiscium petiolare Hook. f. et Thoms, Galium spurium L. and Chrysosplenium lanuginosum Hook. F. Et Thoms.

In Chinese medicine, the pharmacology of each raw medicinal material is as follows:

Radix Fici pumilae: [source] medical material Ji Yuan: for the root of moraceae plants Xue Li.[nature and flavor] bitter in the mouth；Property Cold.[function cures mainly] expelling wind and removing dampness；Channels sootheing and network vessel quickening.Main air pain of dampness syndrome；Sciatica；Psoas muscle labor Damage；Edema；Malaria；Amenorrhea；Postnatal blood stasis is suffered from abdominal pain；Chronic nephritis；Chronic enteritis；Traumatic injury. [extracts] " China's book on Chinese herbal medicine "

Pittosporum tobira tree: [another name] Semen Pittospori Glabrati bar, Semen Pittospori Glabrati [Sichuan], pittosporm root [Guizhou], Xylosmae japonici core, full Caulis et Folium Hyptidis suaveolentis [Guangxi].[source] pittosporum tobira section plant precipice flower pittosporum tobira and Pittosporum glabratum Lindl., enter with root, leaf and seed Medicine.Root can be adopted the whole year, and clean section is dried.Leaf can be adopted at any time, can using fresh herb.Fruit picking in November, shines to foot Dry, make peel brittle, become sepia, break up shell, sieve takes seed.[nature and flavor] root: bitter, pungent, Temperature.Son: bitter, cold.[function cures mainly] root: dispelling, collateral-activating, eliminating stasis to stop pain.For rheumatism joint Inflammation, sciatica, fracture, osteodynia, toothache, hypertension, neurasthenia, emission.[pluck Record] " whole nation Chinese herbal medicine compilation "

Caulis Exbucklandiae Populneae: [another name] Bai Kemu.[source] is the stem of Hamamelidaceae Plants Horse hoof lotus.Annual Can adopt.Chopping is dried or using fresh herb.[nature and flavor] are sour and astringent, temperature, mild toxicity.[function cures mainly] relaxing muscles and tendons to promote blood circulation, Activating collaterals to relieve pain.Treating rheumatic arthritis, sciatica.[extracts] " Chinese medicine voluminous dictionary "

Rhizoma Arthromeritis mairei: [another name] many plumages Rhizoma Arthromeritis mairei, DIWUGONG, Radix scopoliae sinensis, climb ground tiger, Cortex Ampelopsis Aconitifoliae Radicis. [source] fern Polypodiaceae Rhizoma Arthromeritis mairei, is used as medicine with root stock.[nature and flavor] are bitter, micro-puckery, micro- Cold.Slightly poisonous.[function cures mainly] activating collaterals to relieve pain, removing food stagnancy is stagnant, logical stool.Cure mainly food stagnation, stomachache, Abdominal distention, constipation, bones and muscles pain due to rheumatism, sciatica, toothache, headache.[extracts] " whole nation medium-height grass Medicine collects "

Caesalpinia sepiaria Roxb. Varpubescens Tang et wang: [another name] big cattle eighteenth of the twenty, towards emperor, Niu Wang thorn.[source] is leguminous plant hirsutism The root of leaf Semen Caesalpiniae and peel of stem.Summer, autumn gather.[nature and flavor] puckery, property heat, slightly poisonous.[function master Control] root: relieving the exterior syndrome by diaphoresis.Cure the wound wind headache due to common cold, bones and muscles pain and traumatic injury.Peel of stem: external is controlled Rosacea.[extracts] " Chinese medicine voluminous dictionary "

Hygrophila salicifolia: [another name] Herba Hygrophilae Salicifoliae, blue or green Herba Lycopi, arrow clear, the square grass that reduces phlegm, water joint, water arrow be careless, Lock medicine, alter heart Serpentis, Psychotria rubra (Lour.) Poir. flower, Rhizoma seu Herba Elatostematis stewardii, successively, water gallbladder careless with flower on, joint, punching Serpentis, fishbone Grass, ice furuncle medicine, ink dish, spire ink dish.[source] medical material Ji Yuan: for acanthaceous plant Hygrophila salicifolia Herb.[nature and flavor] sweet in the mouth；Micro-hardship；Cool in nature.[function cures mainly] heat-clearing and toxic substances removing；Dissipating blood stasis for subsidence of swelling.Main Time row pyretic toxicity；Erysipelas；Jaundice；Aphtha；Coffee swells and ache；Acute mastitis；Tell nosebleed；Traumatic pain；Fracture； Venom.[extracts] " China's book on Chinese herbal medicine "

Herba seu Radix Metaplexis hemsleyanae: [another name] dish Hemsleya sphaerocarpa Kuang et A. M. Lu, interwined dragon grass, TUXIXIN.[source] medical material Ji Yuan: be five The root of ridge Herba Asari, rhizome or herb.[nature and flavor] are pungent；Temperature.[return through] lung；Stomach warp.[function master Control] dispelling cold by warming the meridian；Relieving cough and resolving phlegm；Reducing swelling and alleviating pain.Main stomachache；Cough with asthma；Traumatic injury；Scald；Serpentis Bite；Toothache is controlled containing coughing.[extracts] " China's book on Chinese herbal medicine "

Step on wing medicine: [another name] Herba crotalariae albidae, TUXIXIN [Yunnan], Hemerocallis citrina Baroni Herba Asari.[source] common violet Section's Viola plant Herba Tephrosiae purpureae common violet, is used as medicine with whole herb with root.Autumn and winter gather, and clean and dry.[nature and flavor] Sweet, micro-pungent, temperature.[function cures mainly] promoting the flow of QI in the collateral by warming the meridian, the infantile malnutrition that disappears spleen invigorating.For rheumatic arthritis, little Youngster's sequela of paralysis, infantile malnutrition, the deficiency of vital energy is dizzy.[extracts] " whole nation Chinese herbal medicine compilation "

Cor Gigeriae Galli seven: [another name], Wu Pao company, Viola arcuata, goat Herba Violae japonicae smelly, female, Herba Violae arcuatae, Red Sedum aizoon L..[source] Violaceae Viola plant sheath handle common violet, with herb, root stock is used as medicine.Autumn After adopt, clean dry.[nature and flavor] are micro-sweet, cool.[function cures mainly] heat-clearing and toxic substances removing, promoting the flow of QI in the collateral by warming the meridian, Promoting blood circulation and hemostasis, synthetism.For traumatic injury, hemoptysis；Mastitis, knife injury are controlled in external, and exploration is fractured, Furuncle swelling toxin.[extracts] " whole nation Chinese herbal medicine compilation "

Os Gallus domesticus bavin: [another name] double Xiang grass, grandma, thin Canis familiaris L. Radix Rhodiolae Yunnanensis, Ramulus et folium buddlejae davidii, purple oil Soviet Union. [source] Labiatae Os Gallus domesticus bavin, is used as medicine with root.[nature and flavor] are bitter, temperature.[function cures mainly] warming the meridian leads to Network, expelling wind and removing dampness.Cure mainly Fengshi Guanjie pain.[extracts] " whole nation Chinese herbal medicine compilation "

Tinomiscium petiolare Hook. f. et Thoms: rattan, milk rattan, false Caulis Fibraureae, Caulis Fibraureae, Caulis Fibraureae, the colour of loess when [another name] Vietnam is big Even, Resina garciniae lotus.[source] medical material Ji Yuan: for root or the stem of menispermaceous plants Tinomiscium petiolare Hook. f. et Thoms.[nature and flavor] Bitter；Cold.[return through] Liver Channel.[function cures mainly] wind-damp dispelling dredging collateral；Eliminating stasis to stop pain；Removing toxic substances.Main air Pain of dampness syndrome；Lumbago；Traumatic injury；Conjunctival congestion and swelling pain；Laryngopharynx swelling and pain.[extracts] " China's book on Chinese herbal medicine "

Galium spurium L.: [another name] Herba Galii Teneri.[source] medical material Ji Yuan: for Maguireothamnus speciosus Galium spurium L. Herb.[nature and flavor] are sweet；Pungent；Micro-hardship；Flat.[function cures mainly] heat-clearing and toxic substances removing；Promoting blood circulation to remove obstruction in the collateral；Only Blood is treating stranguria.Main stranguria；Hematuria；Appendicitis；Paronychia；Traumatic injury；Bones and muscles pain.[extracts] " China's book on Chinese herbal medicine "

Chrysosplenium lanuginosum Hook. F. Et Thoms: [source] medical material Ji Yuan: for the herb of saxifragaceae plant Chrysosplenium lanuginosum Hook. F. Et Thoms.[property Taste] sweet；Cold.[return through] lung, stomach two warp.[function cures mainly] heat-clearing and toxic substances removing, promoting tissue regeneration by astringents, work Blood dredging collateral.It is mainly used to ecthyma, burn and scald, traumatic injury.[extracts] " China's book on Chinese herbal medicine "

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is most preferably as follows: Radix Fici pumilae 16 parts, pittosporum tobira Set 28 parts, Caulis Exbucklandiae Populneae 7 parts, Rhizoma Arthromeritis mairei 15 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 26 parts, Hygrophila salicifolia 15 parts, falls Arrange flowers 21 parts, step on wing medicine 12 parts, Cor Gigeriae Galli 7 20 parts, Os Gallus domesticus bavin 25 parts, Tinomiscium petiolare Hook. f. et Thoms 16 parts, saw saw 28 parts of rattan and Chrysosplenium lanuginosum Hook. F. Et Thoms 21 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is most preferably as follows: Radix Fici pumilae 20 parts, pittosporum tobira Set 25 parts, Caulis Exbucklandiae Populneae 10 parts, Rhizoma Arthromeritis mairei 18 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 22 parts, Hygrophila salicifolia 19 parts, falls Arrange flowers 25 parts, step on wing medicine 15 parts, Cor Gigeriae Galli 7 25 parts, Os Gallus domesticus bavin 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts, saw saw 35 parts of rattan and Chrysosplenium lanuginosum Hook. F. Et Thoms 25 parts.

Hereinafter use example to describe embodiments of the present invention in detail, whereby how the present invention is applied skill Art means solve technical problem, and the process that realizes reaching technique effect can fully understand and implement according to this.

Embodiment 1: tablet

Take Radix Fici pumilae 160g, pittosporum tobira tree 280g, Caulis Exbucklandiae Populneae 70g, Rhizoma Arthromeritis mairei 150g, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 260g, Hygrophila salicifolia 150g, Herba seu Radix Metaplexis hemsleyanae 210g, step on wing medicine 120g, Cor Gigeriae Galli seven 200g, Os Gallus domesticus bavin 250g, Tinomiscium petiolare Hook. f. et Thoms 160g, Galium spurium L. 280g and Chrysosplenium lanuginosum Hook. F. Et Thoms 210g.

Its preparation method comprises the steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, adds relative to mixture quality 4 The ethanol that determining alcohol is 95% again, is heated to reflux 3 hours, extracts, and filters and obtains the first extracting solution； Filter the medicinal residues obtained and add the ethanol that determining alcohol is 95% relative to described medicinal residues quality 2 times, add Hot reflux 3 hours, extracts, and filters and obtains the second extracting solution；First extracting solution and the second extracting solution are closed And, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 2 hours by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that the micropowders of 400 mesh；

3rd step, the micropowders that second step is obtained, add fine relative to the crystallite of its quality 0.3 times Dimension element, 0.15 times of lactose, starch of 0.3 times, sieve, and mix homogeneously is pelletized, and is dried, and adds phase For 0.05 times of magnesium stearate of micropowders quality, granulate, tabletting, make.

Embodiment 2: oral liquid

Take Radix Fici pumilae 200g, pittosporum tobira tree 150g, Caulis Exbucklandiae Populneae 100g, Rhizoma Arthromeritis mairei 180g, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 220g, Hygrophila salicifolia 190g, Herba seu Radix Metaplexis hemsleyanae 250g, step on wing medicine 150g, Cor Gigeriae Galli seven 250g, Os Gallus domesticus bavin 300g, Tinomiscium petiolare Hook. f. et Thoms 200g, Galium spurium L. 350g and Chrysosplenium lanuginosum Hook. F. Et Thoms 250g.

Its preparation method comprises the steps:

The first step, by Radix Fici pumilae, pittosporum tobira tree, Caulis Exbucklandiae Populneae, Rhizoma Arthromeritis mairei, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang and Hygrophila salicifolia are pressed Ratio mixes, and adds relative to the alcohol reflux that mixture 4 times amount determining alcohol is 60% 3 times, and each 3 Hour, to filter, filtrate merges, and reclaims ethanol, and being concentrated into 70 DEG C of relative densities is the mastic of 1.31, Standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 4 times amount water, boils 4 hours, filtering, being concentrated into 70 DEG C of relative densities is the mastic of 1.28；

3rd step, the described mastic mixing that the first step, second step are obtained, 60 DEG C of reduced vacuum are dried, Get dry extract powder；

4th step, added ethanol in the described dried cream powder the 3rd step obtained, obtains containing alcohol mastic, described The alcohol content of containing alcohol mastic is 70%；Described containing alcohol mastic is carried out successively chilling treatment, precipitation process, Filtration treatment, recovery Ethanol Treatment, obtain dealcoholysis mastic, and wherein, the chilling treatment time is 35 hours, Refrigerated storage temperature 1 DEG C；

5th step, will in described dealcoholysis mastic add cane sugar powder, activated carbon, carry out successively heat treated, Filtration treatment, dilution process, and obtain semi-finished product；Described dealcoholysis mastic with the weight ratio of described cane sugar powder is 1∶0.2；Described dealcoholysis mastic is 1: 0.001 with the weight ratio of described activated carbon；Described heat treated Time is 30 minutes, and temperature is 110 DEG C；

Toxicity test:

Acute toxicity testing: application NIH mice 60, SPF level, male and female half and half, body weight 18～28g, Carry out acute toxicity test.Mice is randomly divided into two groups, often group 30, i.e. matched group and administration group is real Test front fasting 12 hours；The tablet dissolved prepared by embodiments of the invention 1 is in water, and (concentration is 7.48g crude drug/ml, maximum concentration) gavage, gavage volume is that (i.e. unit dosage form is 5ml/kg 37.4 crude drugs/kg), matched group gives normal saline, within one day, is administered 2 times, delivery time 6 Hour, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result Showing: compare with matched group, after administration, mice has no notable difference, experiment Continuous Observation 14 days, mice Overall health of patients, diet, drinking-water, body weight increase the most normal.The tablet of the Mouse oral gavage present invention LD50 > 37.4 crude drugs/kg, every day, maximum dosage-feeding was 74.8 crude drugs/kg/ day.The Chinese medicine of the present invention faces Bed dosage is 6.8g crude drug/day/people, and adult's body weight is in terms of 60KG, and average dosage is 0.113g Crude drug/kg/ day.By weighing machine: the Chinese medicine of mice (average weight is in terms of 23g) the oral administration gavage present invention Dosis tolerata is quantity 662 times.Therefore the Chinese medicine acute toxicity of the present invention is low, and clinical application is pacified Entirely.

Long term toxicity test: mice is pressed 10.78,20.35 and 33.48g by the tablet of the embodiment of the present invention 1 After crude drug/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal 3 weeks, result table Bright: Chinese medicine of the present invention is to the hair of rat, behavior, defecation, body weight, organ weights, hemogram, liver The indexs such as renal function, blood glucose, blood fat all have no significant effect, and internal organs naked eyes do not find difference change and group Knitting and check that result shows, after medication 15 weeks and drug withdrawal 3 weeks, each internal organs of rat are all without obvious change.Say Bright Chinese medicine of the present invention is little to toxicity after rat long-term prescription, does not also have difference reaction, application safety after drug withdrawal.

Clinical data:

Case selection: whole 116 example patients are all from the patient that my institute is medical.Be randomly divided into matched group and Treatment group, two groups of each 58 examples.Wherein, treatment group 58 example, male 33 examples, female 25 example；Age 23～ 66 years old；Course of disease 2d～3 years half；Sick in left side 30 example, right side 28 example；Cold-dampness type 16 example, empty Weak type 9 example, trauma type 33 example.Matched group 58 example, male 34 examples, female 24 example；Age 25～67 Year；Course of disease 2d～3 years；Sick in left side 31 example, right side 27 example；Cold-dampness type 16 example, asthenic type 8 Example, trauma type 34 example.Two groups of patients are each in sex, age, the course of disease, site of pathological change and clinical manifestation etc. Aspect compares no difference of science of statistics, has comparability.

Diagnostic criteria: the 1. radiated pain in sciatic nerve distributed areas, cough, sneeze etc. often make pain Pain increases the weight of.2. there are the pressure pain point, common pressure pain point to be along sciatic nerve areal area: (1) buttocks midpoint.(2) Incisura ischiadica.(3) den.(4) calf point.(5) ankle point.3. there is difference in sciatic nerve domination district The motion of degree, feeling, reflect and autonomic nerve obstacle, as weak in big toe dorsiflex power, little leg outer side is felt Go down, Achilles tendon reflex disappear, straight-leg raising test and strengthen test, neck sign, chin breast test, with Buttocks test and the pressure measurement by compression of neck positive etc..4. can there be corresponding medical history, lab testing finding.

Therapeutic Method:

Matched group: use the treatment of doctor trained in Western medicine routine acupuncture-moxibustion method.Acupoint selection: take bladder meridian through cave and foot Few sun gallbladder meridian is through cave, with Huantiao, Yang Ling as master point.Dialectical genus cold-dampness type person (is invaded because of the heresy of cold-damp and is sent out Disease, disease see panic attacks often invaded along pathogenic factor and passages through which vital energy circulates, or up and down migratory arthralgia caused by wind pain, or weigh not Moving, friendship of aching is made, with numbness of the skin, deep and hesitant pulse or tight, white and thin fur or the most greasy) add moxibustion；Weak Type person is (because deficiency of the liver and kindey, QI and blood consumption wound, or body constitution element lose and send out primary disease.Disease sees lustreless complexion, spirit Not filling, lassitude loin and legs is weak, stride difficulty, and after fatigue, then pain is acute whenever, then alleviation of pain, deep-thready pulse time sleeping Or moisten, pale tongue and deep red, thin fur is sliding or smooth or light stripping) add shen shu, tsu san li；Trauma type person (because of Morbidity is clashed in sprain and contusion, disease see injured after lumbago such as folding in rain, even and thigh pivot is to lower limb stock, pitching, turn the most not Profit, hesitant pulse, red tongue, thin fur or light) add blood-letting in committee.Operational approach: with 75% at acupoint Cotton ball soaked in alcohol routine disinfection, takes No. 28 5 cun of acupuncture needles with twisted inserting needle, gives even reinforcing-reducing method maneuver, work as acupuncture To certain depth, continuing twisted shifting booster injection sense, HUANTIAO acupoint pin sense requires as electric shock, downward by buttocks Diffuse to instep, toe；Gb 34 pin sense is diffused to instep.Let the acupuncture needle remain at a certain point 30min, every 10min twisted 1 Secondary.1 times/day, be for 10 times 1 course for the treatment of, is spaced 2d, carries out second course for the treatment of.

Treatment group: on the basis of matched group, takes the tablet of the embodiment of the present invention 1,3 pieces/times, and 3 Times/day；Interim not drug withdrawal.

Curative effect determinate standard: cure: symptom and sign are wholly absent, and observe 1 year non-recidivist.Take a turn for the better: Symptom and sign disappear substantially, aching and tired in obvious inducement (catching cold, overwork) sense suffering limb afterwards, hypodynia, and half Non-recidivist more than year；Or symptom and sign significantly improve, but still have and send out author.Invalid: symptom and body Levy and slightly improve, but still recurrent exerbation or have no improvement person.

Therapeutic outcome: see table:

Group	Number	Cure	Take a turn for the better	Invalid	Total effective rate (%)
						Treatment group	58	42	14	2	56 (96.55%)
Matched group	58	31	19	8	50 (86.21%)

By upper table, matched group uses Chinese medicine of the present invention, it is possible to associating doctor trained in Western medicine routine acupuncture-moxibustion side Sciatica is treated in ruling by law, it is possible to be effectively improved therapeutic effect.

Untoward reaction: over the course for the treatment of, gastrointestinal upset, Liver and kidney all do not occur to treatment group in all cases Functional lesion or other untoward reaction.

Model case: Ma, man, 38 years old.Suffering from sciatica before 2 years, falls ill in left side.Patient night Between the pain increased.Taking Western medicine, curative effect is not good enough institute goes to a doctor to me, is cold-dampness type according to symptom typing always, Taking the tablet of the embodiment of the present invention 1 on the basis of acupuncture, after 2 courses for the treatment of, symptom and sign are complete Disappear, follow up a case by regular visits to 1 year not recur, cure.

The above, be only presently preferred embodiments of the present invention, is not that the present invention makees other form Restriction, any those skilled in the art are changed possibly also with the technology contents of the disclosure above Or it is modified as the Equivalent embodiments of equivalent variations.But every without departing from technical solution of the present invention content, depend on Any simple modification, equivalent variations and remodeling above example made according to the technical spirit of the present invention, Still fall within the protection domain of technical solution of the present invention.

Claims

1. the Chinese medicine combining acupuncture and moxibustion therapy sciatica, it is characterised in that include following crude drug Material: Radix Fici pumilae, pittosporum tobira tree, Caulis Exbucklandiae Populneae, Rhizoma Arthromeritis mairei, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang, Hygrophila salicifolia, Herba seu Radix Metaplexis hemsleyanae, step on Wing medicine, Cor Gigeriae Galli seven, Os Gallus domesticus bavin, Tinomiscium petiolare Hook. f. et Thoms, Galium spurium L. and Chrysosplenium lanuginosum Hook. F. Et Thoms.

2. Chinese medicine as claimed in claim 1, it is characterised in that the weight of each raw medicinal material in described Chinese medicine Amount portion rate is as follows: Radix Fici pumilae 10～20 parts, pittosporum tobira tree 20～45 parts, Caulis Exbucklandiae Populneae 5～20 parts, phoenix Tail Radix scopoliae sinensis 15～30 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 20～30 parts, Hygrophila salicifolia 5～20 parts, Herba seu Radix Metaplexis hemsleyanae 15～25 Part, step on wing medicine 5～15 parts, Cor Gigeriae Galli 7 15～25 parts, Os Gallus domesticus bavin 20～40 parts, Tinomiscium petiolare Hook. f. et Thoms 10～20 Part, Galium spurium L. 20～35 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 15～25 parts.

3. Chinese medicine as claimed in claim 1 or 2, it is characterised in that each raw medicinal material in described Chinese medicine Ratio of weight and number as follows: Radix Fici pumilae 15～20 parts, pittosporum tobira tree 25～30 parts, Caulis Exbucklandiae Populneae 7～15 parts, Rhizoma Arthromeritis mairei 15～25 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 20～28 parts, Hygrophila salicifolia 15～20 parts, Herba seu Radix Metaplexis hemsleyanae 18～ 25 parts, step on wing medicine 10～15 parts, Cor Gigeriae Galli 7 18～25 parts, Os Gallus domesticus bavin 25～33 parts, Tinomiscium petiolare Hook. f. et Thoms 15～ 20 parts, Galium spurium L. 25～35 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 20～25 parts.

4. the Chinese medicine as described in claims 1 to 3, it is characterised in that each raw medicinal material in described Chinese medicine Ratio of weight and number as follows: Radix Fici pumilae 16 parts, 28 parts of pittosporum tobira tree, Caulis Exbucklandiae Populneae 7 parts, Rhizoma Arthromeritis mairei 15 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 26 parts, Hygrophila salicifolia 15 parts, Herba seu Radix Metaplexis hemsleyanae 21 parts, step on wing medicine 12 parts, Cor Gigeriae Galli 7 20 Part, Os Gallus domesticus bavin 25 parts, Tinomiscium petiolare Hook. f. et Thoms 16 parts, Galium spurium L. 28 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 21 parts.

5. the Chinese medicine as described in Claims 1-4, it is characterised in that each raw medicinal material in described Chinese medicine Ratio of weight and number as follows: Radix Fici pumilae 20 parts, 25 parts of pittosporum tobira tree, Caulis Exbucklandiae Populneae 10 parts, Rhizoma Arthromeritis mairei 18 parts, Caesalpinia sepiaria Roxb. Varpubescens Tang et wang 22 parts, Hygrophila salicifolia 19 parts, Herba seu Radix Metaplexis hemsleyanae 25 parts, step on wing medicine 15 parts, Cor Gigeriae Galli 7 25 Part, Os Gallus domesticus bavin 30 parts, Tinomiscium petiolare Hook. f. et Thoms 20 parts, Galium spurium L. 35 parts and Chrysosplenium lanuginosum Hook. F. Et Thoms 25 parts.

6. the Chinese medicine as described in claim 1 to 5, it is characterised in that when the dosage form of described Chinese medicine is sheet During agent, its preparation method comprises the following steps:

7. the Chinese medicine as described in claim 1 to 5, it is characterised in that when the dosage form of described Chinese medicine is mouth When taking liquor, its preparation method comprises the following steps:

8. the preparation method of Chinese medicine described in claim 1 to 5, it is characterised in that the dosage form of described Chinese medicine For tablet, its preparation method comprises the following steps:

9. the preparation method of Chinese medicine described in claim 1 to 5, it is characterised in that when the agent of described Chinese medicine When type is oral liquid, its preparation method comprises the following steps: