CN105997609A - Moisture preserving composition and preparation method thereof - Google Patents
Moisture preserving composition and preparation method thereof Download PDFInfo
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- CN105997609A CN105997609A CN201610312886.2A CN201610312886A CN105997609A CN 105997609 A CN105997609 A CN 105997609A CN 201610312886 A CN201610312886 A CN 201610312886A CN 105997609 A CN105997609 A CN 105997609A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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Abstract
The invention belongs to the field of cosmetics, and particularly relates to a moisture preserving composition and a preparation method thereof. The moisture preserving composition is mainly prepared from plant extract liposome, allantoin, hydroxyethyl urea, xanthan gum and glycerin. The plant extract is composed of bitter gourd extract, herba portulacae extract and mallow extract. The preparation method of the moisture preserving composition comprises the steps that the plant extract is subjected to liposome wrapping, then, the liposom is mixed with the other components, and the moisture preserving composition is obtained. The moisture preserving composition can reach a corium layer, repair matrix cells of the corium layer, promote synthesis of collagen and elastin and improve the formation and the structure of the corium layer matrix, therefore the effects of deep moisturizing and corium layer repairing are achieved, and the problem of dry skin is fundamentally solved.
Description
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of moisture-keeping composition and preparation method thereof.
Background technology
Along with the development of cosmetics industry, cosmetics have become as a kind of requisite article of everyday use in people's life.
At present, in the environment of people live in air-conditioning, dehumidifier for a long time, the phenomenon of skin hydropenia is more and more severeer, accelerates skin
Aging rate.Due to traditional moisture-keeping cosmetics, to there is assimilation effect the best, and moistening effect is lasting, and there is thorn
Swash the defect of property and gradually eliminated by market.At present, people increasingly like using moistening effect good, natural non-stimulated
The moisture-keeping cosmetics of plant extract.
Chinese patent CN101816624 discloses a kind of moisture-keeping cosmetics and preparation method thereof, and described moisture-keeping cosmetics is by whale
Wax stearyl alcohol, Butyrospermum Parkii Oil, hydrogenated polydecene, polydimethylsiloxane, sucrose stearate, octanoic acid, oxybenzene
Propyl ester, methyl hydroxybenzoate, glycerol stearate esters, tocopherol acetas, Cyclomethicone, EDETATE SODIUM,
Allantoin, lauryl alcohol phosphate ester potassium, propylene glycol, glycerol, carbomer, aminomethyl propanol, hyaluronate sodium, glycine betaine,
Pantothenylol, double (methylols) narrow oxazolidinyl urea, essence, palmitoyl oligopeptide, lecithin, Rosa Damascena Extract, Canis familiaris L. tooth
Flos Rosae Multiflorae fruit oil, Thallus Laminariae extract, sucrose palmitate and water composition.Although the cosmetics prepared can be at skin
Top layer forms protective barrier, prevents scaly dry skin, but, these cosmetics contain more chemical substance, there is skin
Bigger stimulation, and production cost is higher, greatly limits the promotion and application of this moisture-keeping cosmetics.
Chinese patent CN102018652B discloses a kind of binary moisturizing system skin care item, and described skin care item are by leucojum aestivum
Bulb extract, sponge extract, sodium lactate and pentanediol composition, this Moisturizer can be set up raw in skin surface
State lock moisture film and bottom get through skin aquaporin, top layer lock water, bottom moisturizing, form skin binary moisturizing system.But,
Leucojum aestivum bulb extract and sponge extract are oxidizable, and moistening effect persistence is poor, it is impossible to reach modern to guarantor
The requirement of wet moisturizing effect, is unfavorable for the promotion and application of these binary moisturizing system skin care item.
Chinese patent application 201210375730.0 discloses a kind of pure natural moisture-keeping cosmetics, and described cosmetics are to use sea
The natural plant extraction things such as algae extract, olive oil, aloe extract and akala extract are that active component is made, and use
During these cosmetics, have health, nothing relies on, and the advantage substantially having no side effect.But, seaweed extract thing, Aloe extraction
Taking thing and akala extract is oxidizable, moistening effect persistence is poor, and the moisturizing ingredient of extract can only arrive horny layer,
Skin corium cannot be penetrated into, thus cannot fundamentally solve xerodermatic problem.
Therefore, study and send out that to output a kind of moistening effect good, moistening effect persistently for a long time, nonirritant, can fundamentally solve
Certainly the cosmetics of xerosis cutis problem are still the emphasis of current cosmetic field research.
Summary of the invention
In order to overcome, active component in prior art moisture-keeping cosmetics is oxidizable, moistening effect persistence is poor, moisture-keeping function
Top layer can be rested on, it is impossible to the shortcoming fundamentally solving xerosis cutis problem, it is an object of the invention to provide a kind of moisturizing
Compositions and preparation method thereof, to solve the problems referred to above.
The invention provides a kind of moisture-keeping composition, including following components and parts by weight thereof:
Plant extract liposome 8-18 part, allantoin 0.1-1.5 part, ethoxy urea 2-8 part, xanthan gum 0.2-2 part and
Glycerol 10-16 part, described plant extraction liquid is made up of balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution.
Further, described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 16 parts, allantoin 0.8 part, ethoxy urea 4 parts, xanthan gum 1 part and glycerol 14 parts.
Further, described plant extraction liquid is by balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution by volume
4-6: 2-4: 1-3 composition.
Further, described plant extraction liquid is by balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution by volume
5: 3: 2 compositions.
Further, the preparation method of described balsam pear extract is:
Fructus Momordicae charantiae is cleaned and removes seed, add 4-6 times of water heating and refluxing extraction of above-mentioned Fructus Momordicae charantiae raw material weight 2-3 time, each 1-2h,
Filter, merging filtrate, obtain balsam pear extract.
Further, the preparation method of described Herba Portulacae extract is:
By Herba Portulacae clean dry, adding above-mentioned 2-4 times of concentration of Herba Portulacae raw material weight is the ethanol solution of 65-75%,
Extract 2-3 time under conditions of temperature is 10-20 DEG C, each 2-3h, filter, merging filtrate, filtrate decompression is reclaimed
Ethanol, obtains Herba Portulacae extract.
Further, the preparation method of described Radix Malvae sylvestris extracting solution is:
By Radix Malvae sylvestris clean dry, adding above-mentioned 2-3 times of concentration of Radix Malvae sylvestris raw material weight is the ethanol solution of 70-80%, ultrasonic
Ripple extracts 2-3 time, and the power of described ultrasound wave is 400-500W, each 1-2h, filters, and merging filtrate, by filtrate
Decompression recycling ethanol, obtains Radix Malvae sylvestris extracting solution.
It addition, present invention also offers the preparation method of a kind of moisture-keeping composition, comprise the following steps:
Phospholipid, cholesterol and emulsifying agent are added dissolving in dehydrated alcohol by S1, add water, fully stir in 33-45 DEG C
Mix and homogenizing, obtain mixed liquor I；
In the mixed liquor I that balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution addition step S1 is obtained by S2, stir
Mix uniformly, filter, obtain filtrate, by filtrate through ultrasonic Treatment, separate to obtain plant extract liposome；
S3, by allantoin, ethoxy urea, xanthan gum and glycerol mix and blend, homogenizing, obtains mixed liquor I I；
Mixed liquor I I that the plant extract liposome that step S2 is obtained by S4 obtains with step S3 is mixed homogeneously, and is dried,
Obtain.
In addition, present invention also offers described moisture-keeping composition purposes in preparing moisture-keeping cosmetics, using should
During moisture-keeping composition, directly add in multiple formulations system with the addition of 10-25%, such as moisture retention water, emulsion, cream
With facial film etc., make corresponding moisture retention water, moisturizing emulsion, moisturizing cream and moisture saver mask etc..
Fructus Momordicae charantiae (Momordica charantia L.) is Cucurbitaceae Momordica plant, and Fructus Momordicae charantiae Aqueous extracts is raw rich in vitamin B, dimension
Element C, can effectively desalinate pigment, to make that skin and muscles are fair delicate, the most also has antiinflammatory, antioxidative effect, Dens Equi
Herba Amaranthi tricoloris (Portulaca oleracea L.) is Portulacaceae Portulaca herbaceous plant, and its extracting solution has antiallergic, removes certainly
By the effect of base, Radix Malvae sylvestris (Malva sinensis Cavan.) is Malvaceae mallow herbaceous plant, and it is rich in anthocyanidin, Huang
The effective ingredient such as ketone, tannic acid and vitamin, can alleviate scytitis, prevent the effect of skin aging and moisturizing.
Being mixed according to a certain volume by balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution that the present invention provides forms
Plant extraction liquid, finds through test, it has significant moisturizing, moisture-keeping function, and moistening effect persistence is good.Separately
Outward, the present invention utilizes liposome technology, is wrapped in liposome by plant extraction liquid, due to liposome and biomembrane
Structure is similar, is inserted in the lipid layer of cell membrane, and the plant extraction liquid being wrapped in liposome is transported corium
Layer.Balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution in plant extraction liquid have worked in coordination with reparation base in skin corium
Cell plastid, promotes collagen protein and the synthesis of elastin laminin, improves the Nomenclature Composition and Structure of Complexes of skin corium substrate, thus reach deep
Layer moisturizing and the effect of maintenance skin corium, can fundamentally solve xerodermatic problem.
No. CAS of allantoin in the moisture-keeping composition that the present invention provides be 97-59-6, be that one is nontoxic, nonirritant,
Without hypersensitive white crystal, it has antioxidation, the effect of Glycerin.No. CAS of ethoxy urea is 2078-71-9,
It can increase moisture content of skin, alleviates and is dried, and fills up microgroove, increases skin elasticity.Allantoin is combined with ethoxy urea
Use and can effectively pin intracellular moisture, reduce the loss of ICW, this moisture-keeping composition can be extended
Moisture preserving time.
In a word, the moisture-keeping composition that the present invention provides, compared with prior art have the advantage that
1) moisture-keeping composition that the present invention provides utilizes liposome technology, is wrapped in liposome by plant extraction liquid, can
So that plant extraction liquid arrives in skin corium, repair stromal cell, promote collagen protein and the synthesis of elastin laminin, improve
The Nomenclature Composition and Structure of Complexes of skin corium substrate, thus reach deep water supplement and the effect of maintenance skin corium, can fundamentally solve
Xerodermatic problem.
2) moisture-keeping composition that the present invention provides can also persistently supplement skin moisture, strengthens elasticity and the plumpness of skin, and
And it can also form protective barrier at skin surface, prevent water loss, further extend the guarantor of this moisture-keeping composition
The wet time, strengthen moistening effect.
Detailed description of the invention
Further describing the present invention below by way of specific embodiment, the present invention is not limited only to following example.In the present invention
In the range of or without departing from present disclosure, spirit and scope, change that the present invention is carried out, combine or replace
Change, will be apparent to the person skilled in the art, and be included within the scope of the present invention.
Embodiment 1, the preparation of balsam pear extract
Fructus Momordicae charantiae is cleaned and removes seed, add 5 times of water heating and refluxing extraction of above-mentioned Fructus Momordicae charantiae raw material weight 2 times, each 2h, mistake
Filter, merging filtrate, obtain balsam pear extract.
Embodiment 2, the preparation of Herba Portulacae extract
By Herba Portulacae clean dry, adding 4 times of concentration of above-mentioned Herba Portulacae raw material weight is the ethanol solution of 70%, in temperature
Extract 2 times under conditions of being 15 DEG C, each 2h, filter, merging filtrate, by decompression filtrate recycling ethanol, obtain Dens Equi
Herba Amaranthi tricoloris extracting solution.
Embodiment 3, the preparation of Radix Malvae sylvestris extracting solution
By Radix Malvae sylvestris clean dry, adding 2 times of concentration of above-mentioned Radix Malvae sylvestris raw material weight is the ethanol solution of 75%, ultrasonic extraction
2 times, the power of described ultrasound wave is 450W, each 2h, filters, merging filtrate, by decompression filtrate recycling ethanol,
Obtain Radix Malvae sylvestris extracting solution.
Embodiment 4, a kind of moisture-keeping composition
Described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 8 parts, allantoin 0.4 part, ethoxy urea 2 parts, xanthan gum 0.6 part and glycerol 10
Part, described plant extraction liquid is made up of by volume balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution at 4: 4: 3.
Preparation method:
0.5kg phospholipid, 0.5kg cholesterol and 2kg emulsifying agent are added dissolving in 4kg dehydrated alcohol by S1, add 4kg
Water, is sufficiently stirred in 33 DEG C and homogenizing, obtains mixed liquor I；
In the mixed liquor I that balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution addition step S1 is obtained by S2, stir
Mix uniformly, filter, obtain filtrate, by filtrate through ultrasonic Treatment, separate to obtain plant extract liposome；
S3, by allantoin, ethoxy urea, xanthan gum and glycerol mix and blend, homogenizing, obtains mixed liquor I I；
Mixed liquor I I that the plant extract liposome that step S2 is obtained by S4 obtains with step S3 is mixed homogeneously, and is dried,
Obtain.
Embodiment 5, a kind of moisture-keeping composition
Described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 16 parts, allantoin 0.8 part, ethoxy urea 4 parts, xanthan gum 1 part and glycerol 14 parts,
Described plant extraction liquid is made up of by volume balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution at 5: 3: 2.
Preparation method:
0.5kg phospholipid, 0.5kg cholesterol and 2kg emulsifying agent are added dissolving in 4kg dehydrated alcohol by S1, add 4kg
Water, is sufficiently stirred in 40 DEG C and homogenizing, obtains mixed liquor I；
In the mixed liquor I that balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution addition step S1 is obtained by S2, stir
Mix uniformly, filter, obtain filtrate, by filtrate through ultrasonic Treatment, separate to obtain plant extract liposome；
S3, by allantoin, ethoxy urea, xanthan gum and glycerol mix and blend, homogenizing, obtains mixed liquor I I；
Mixed liquor I I that the plant extract liposome that step S2 is obtained by S4 obtains with step S3 is mixed homogeneously, and is dried,
Obtain.
Embodiment 6, a kind of moisture-keeping composition
Described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 18 parts, allantoin 1.4 parts, ethoxy urea 8 parts, xanthan gum 2 parts and glycerol 16 parts,
Described plant extraction liquid is made up of by volume balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution at 6: 2: 1.
Preparation method:
0.5kg phospholipid, 0.5kg cholesterol and 2kg emulsifying agent are added dissolving in 4kg dehydrated alcohol by S1, add 4kg
Water, is sufficiently stirred in 45 DEG C and homogenizing, obtains mixed liquor I；
In the mixed liquor I that balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution addition step S1 is obtained by S2, stir
Mix uniformly, filter, obtain filtrate, by filtrate through ultrasonic Treatment, separate to obtain plant extract liposome；
S3, by allantoin, ethoxy urea, xanthan gum and glycerol mix and blend, homogenizing, obtains mixed liquor I I；
Mixed liquor I I that the plant extract liposome that step S2 is obtained by S4 obtains with step S3 is mixed homogeneously, and is dried,
Obtain.
Comparative example 1, a kind of moisture-keeping composition
Described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 16 parts, ethoxy urea 4.8 parts, xanthan gum 1 part and glycerol 14 parts, state plant extract
Liquid is made up of by volume balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution at 5: 3: 2.
Preparation method is similar to Example 2.
Difference with embodiment 5 is, does not add allantoin, increases the parts by weight of ethoxy urea.
Comparative example 2, a kind of moisture-keeping composition
Described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 16 parts, allantoin 0.8 part, ethoxy urea 4 parts, xanthan gum 1 part and glycerol 14 parts,
Described plant extraction liquid is made up of by volume balsam pear extract and Herba Portulacae extract at 6: 4.
Preparation method is similar to Example 5.
Difference with embodiment 5 is, described plant extraction liquid is by balsam pear extract and Herba Portulacae extract 6: 4 groups by volume
Become.
Comparative example 3, a kind of moisture-keeping composition
Described moisture-keeping composition includes following components and parts by weight thereof:
Plant extract liposome 16 parts, allantoin 0.8 part, ethoxy urea 4 parts, xanthan gum 1 part and glycerol 14 parts,
Described plant extraction liquid is made up of by volume balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution at 1: 1: 1.
Preparation method is similar to Example 2.
Difference with embodiment 5 is, described plant extraction liquid is pressed by balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution
Volume ratio 1: 1: 1 forms.
Test example one, the moisturizing test of moisture-keeping composition
1, subjects: choose the mice of 70 12-13 week old, is provided by Nanjing Experimental Animal Center.
2, test material: embodiment 4, embodiment 5, embodiment 6, comparative example 1, comparative example 2 and comparative example 3 preparation
Moisture-keeping composition, butanediol solution.
3, test method: 70 mices shaver is shaved off back by hair, exposes the skin of size about 2cm × 3cm, so
After be randomly divided into 7 groups, often group 10, using butanediol solution as blank, respectively matched group, embodiment 4
Group, embodiment 5 groups, embodiment 6 groups, comparative example 1 group, comparative example 2 groups and comparative example 3 groups.The moisture retention water of each group
Composition is as follows:
Matched group: butanediol solution；
Embodiment 4 groups: add the butanediol solution of the moisture-keeping composition of 10% embodiment 4 preparation；
Embodiment 5 groups: add the butanediol solution of the moisture-keeping composition of 10% embodiment 5 preparation；
Embodiment 6 groups: add the butanediol solution of the moisture-keeping composition of 10% embodiment 6 preparation；
Comparative example 1 group: add the butanediol solution of the moisture-keeping composition of 10% comparative example 1 preparation；
Comparative example 2 groups: add the butanediol solution of the moisture-keeping composition of 10% comparative example 2 preparation；
Comparative example 3 groups: add the butanediol solution of the moisture-keeping composition of 10% comparative example 3 preparation；
Each group of moisture retention water is applied in the baring skin of mice, then mice is placed under dehumidifier environment and exposes, every day
Expose 6 hours, continue 15 days；Then carry out mouse back baring skin moisture determination, take off depilation with card punch
Rear skin histology 0.5g, accurate title skin weight in wet base, place 48h in 80 DEG C of drying baker, claim skin dry weight.And by following
The formula measurement skin percentage of moisture: the skin percentage of moisture=(skin weight in wet base-dry weight)/weight in wet base × 100%.
4, result of the test:
Result of the test is as shown in table 1.
The test data of table 1 mouse skin water content
| Group | The skin percentage of moisture |
| Matched group | 30.26% |
| Embodiment 4 groups | 71.56% |
| Embodiment 5 groups | 74.35% |
| Embodiment 6 groups | 70.42% |
| Comparative example 1 group | 51.28% |
| Comparative example 2 groups | 36.94% |
| Comparative example 3 groups | 57.22% |
As shown in Table 1, the mouse skin smearing the moisture retention water adding moisture-keeping composition prepared by embodiment of the present invention 4-5 is put down
All the percentage of moisture is more than 70%, and smears the mouse skin of the moisture retention water adding moisture-keeping composition prepared by comparative example 1-3
The average percentage of moisture, less than 58%, illustrate that the formula of the moisture-keeping composition that the present invention provides is reasonable, science, each component association
With acting the effect strengthening moisturizing.
Test example two, the moisturizing test of moisture-keeping composition
1, subjects: select 50 female volunteers, age 20-35 year.
2, test material: embodiment 5, comparative example 1, comparative example 2 and the moisture-keeping composition of comparative example 3 preparation, butanediol
Liquid.
3, test method:
50 volunteers are randomly divided into 5 groups, using butanediol solution as blank, often organize 10 people, the most right
According to group, embodiment 5 groups, comparative example 1 group, comparative example 2 groups and comparative example 3 groups, the moisture retention water of each group is as follows:
Matched group: butanediol solution；
Embodiment 5 groups: add the butanediol solution of the moisture-keeping composition of 10% embodiment 5 preparation；
Comparative example 1 group: add the butanediol solution of the moisture-keeping composition of 10% comparative example 1 preparation；
Comparative example 2 groups: add the butanediol solution of the moisture-keeping composition of 10% comparative example 2 preparation；
Comparative example 3 groups: add the butanediol solution of the moisture-keeping composition of 10% comparative example 3 preparation；
Inside the front wrist of the right-hand man that each group of moisture retention water is applied in respectively volunteer (24mm × 45mm), three times a day,
Using 15 days continuously, after the 24h of the 15th day, be 25 DEG C in room temperature, humidity is utilization under conditions of 50%
Corneometer CM 825 is cuticular moisture after measuring 30min and 8h.
4, result of the test:
Result of the test is as shown in table 2.
The moisturizing test of table 2 moisture-keeping composition
| Group | Smear moisture after 30min | Smear moisture after 8h |
| Matched group | 53.6% | 20.4% |
| Embodiment 5 groups | 87.5% | 70.4% |
| Comparative example 1 group | 69.6% | 38.5% |
| Comparative example 2 groups | 60.7% | 26.4% |
| Comparative example 3 groups | 72.5% | 40.3% |
As shown in Table 2, use the moisture retention water of the moisture-keeping composition being added with the embodiment of the present invention 5 preparation after 30min
Moisture is 87.5%, and the moisture after 8h is 70.4%, and a point water content rate of descent is 17.1%, and uses interpolation
There is the moisture retention water of moisture-keeping composition prepared by the comparative example 1-3 moisture after the 30min water less than 75%, after 8h
Point content is less than 45%, and point water content rate of descent, more than 30%, illustrate the formula conjunction of the moisture-keeping composition that the present invention provides
Reason, science, the collaborative moisture preserving time that can effectively extend moisture-keeping composition of each component, strengthen moistening effect.
Claims (10)
1. a moisture-keeping composition, it is characterised in that include following components and parts by weight thereof:
Plant extract liposome 8-18 part, allantoin 0.1-1.5 part, ethoxy urea 2-8 part, xanthan gum 0.2-2 part and glycerol
10-16 part；Described plant extraction liquid is made up of balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution.
2. moisture-keeping composition as claimed in claim 1, it is characterised in that include following components and parts by weight thereof:
Plant extract liposome 16 parts, allantoin 0.8 part, ethoxy urea 4 parts, xanthan gum 1 part and glycerol 14 parts.
3. moisture-keeping composition as claimed in claim 1 or 2, it is characterised in that described plant extraction liquid by balsam pear extract,
Herba Portulacae extract and Radix Malvae sylvestris extracting solution 4-6: 2-4: 1-3 composition by volume.
4. moisture-keeping composition as claimed in claim 3, it is characterised in that described plant extraction liquid is by balsam pear extract, Dens Equi
Herba Amaranthi tricoloris extracting solution and Radix Malvae sylvestris extracting solution 5: 3: 2 composition by volume.
5. moisture-keeping composition as claimed in claim 1, it is characterised in that the preparation method of described balsam pear extract is:
Fructus Momordicae charantiae is cleaned and removes seed, add 4-6 times of water heating and refluxing extraction of above-mentioned Fructus Momordicae charantiae raw material weight 2-3 time, each 1-2h, mistake
Filter, merging filtrate, obtain balsam pear extract.
6. moisture-keeping composition as claimed in claim 1, it is characterised in that the preparation method of described Herba Portulacae extract is:
By Herba Portulacae clean dry, adding above-mentioned 2-4 times of concentration of Herba Portulacae raw material weight is the ethanol solution of 65-75%, in temperature
Degree extracts 2-3 time under conditions of 10-20 DEG C, and each 2-3h filters, merging filtrate, by decompression filtrate recycling ethanol,
Obtain Herba Portulacae extract.
7. moisture-keeping composition as claimed in claim 1, it is characterised in that the preparation method of described Radix Malvae sylvestris extracting solution is:
By Radix Malvae sylvestris clean dry, adding above-mentioned 2-3 times of concentration of Radix Malvae sylvestris raw material weight is the ethanol solution of 70-80%, and ultrasound wave carries
Taking 2-3 time, the power of described ultrasound wave is 400-500W, each 1-2h, filters, and merging filtrate, by filtrate decompression
Reclaim ethanol, obtain Radix Malvae sylvestris extracting solution.
8. the preparation method of the moisture-keeping composition as described in claim 1-7 is arbitrary, it is characterised in that comprise the following steps:
Phospholipid, cholesterol and emulsifying agent are added dissolving in dehydrated alcohol by S1, add water, are sufficiently stirred for also in 33-45 DEG C
Homogenizing, obtains mixed liquor I；
In the mixed liquor I that balsam pear extract, Herba Portulacae extract and Radix Malvae sylvestris extracting solution addition step S1 is obtained by S2, stirring is all
Even, filter, obtain filtrate, by filtrate through ultrasonic Treatment, separate to obtain plant extract liposome；
S3, by allantoin, ethoxy urea, xanthan gum and glycerol mix and blend, homogenizing, obtains mixed liquor I I；
Mixed liquor I I that the plant extract liposome that step S2 is obtained by S4 obtains with step S3 is mixed homogeneously, and is dried, i.e.
?.
9. the purposes in preparing moisture-keeping cosmetics of the moisture-keeping composition as described in claim 1-7 is arbitrary.
10. purposes as claimed in claim 9, it is characterised in that the addition of described moisture-keeping composition is 10-25%.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109464323A (en) * | 2018-11-21 | 2019-03-15 | 广州瑞萱生物科技有限公司 | A kind of face frost and preparation method thereof restoring skin elasticity |
| CN111315241A (en) * | 2017-10-05 | 2020-06-19 | 普拉克生化公司 | Lactate powder and preparation method thereof |
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| CN103301035A (en) * | 2013-05-29 | 2013-09-18 | 美晨集团股份有限公司 | Skin moistening product for preventing skin from being dried and chapped and preparation method of skin moistening product |
| FR2933608B1 (en) * | 2008-07-11 | 2014-01-10 | Lvmh Rech | NEW USE OF EXTRACT OF LARGE MAUVE MOISTURIZING AGENT, AND COSMETIC COMPOSITION CONTAINING SAME |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111315241A (en) * | 2017-10-05 | 2020-06-19 | 普拉克生化公司 | Lactate powder and preparation method thereof |
| CN109464323A (en) * | 2018-11-21 | 2019-03-15 | 广州瑞萱生物科技有限公司 | A kind of face frost and preparation method thereof restoring skin elasticity |
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