CN105997534A - Eyelash increasing liquid and preparation method thereof - Google Patents
Eyelash increasing liquid and preparation method thereof Download PDFInfo
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- CN105997534A CN105997534A CN201610613620.1A CN201610613620A CN105997534A CN 105997534 A CN105997534 A CN 105997534A CN 201610613620 A CN201610613620 A CN 201610613620A CN 105997534 A CN105997534 A CN 105997534A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention provides eyelash increasing liquid which comprises a component A, a component B and a component C, wherein the component A comprises 0.15-0.25wt% of preservative and 0.60-1.0wt% of 1,3-butanediol; the component B comprises 0.01-3wt% of fullerene, 0.01-10wt% of palmitoyl oligopeptide-15 and 0.5-2wt% of water-soluble VE; and the component C comprises 1-10wt% of glycerol, 0.05-0.2wt% of allantoin, 0.1-1.5wt% of D-panthenol and the balance of deionized water. By compounding fullerene and palmitoyl oligopeptide-15 and matching the compound with the component A and the component C, the eyelash increasing liquid provided by the invention can obviously promote eyelash increase.
Description
Technical field
The present invention relates to daily chemical products technical field, particularly relate to a kind of eyelash growing liquid and preparation method thereof.
Background technology
Ciliogensis is longer than margo palpebrae anterior lip, is arranged in 2～3 row, short and bend；Upper eyelid eyelashes are many and grow, lower eyelid eyelashes short and
Few.In general, a healthy individuality has about 200 eyelashes, and the eyelashes of woman are more than the eyelashes of man.Eyelashes are the most raw
Long to about 1cm, and direction and angle can change.
Along with society and expanding economy, people are more and more higher to the requirement of physical beauty, including increasing ciliary length.
Completely, plentiful eyelashes can increase beauty or the captivation of a people, say, that appearance is increasingly noted by society, people
Can promote effect and the impression of entirety, especially note beautifying eyes and prolongation or encryption eyelash and eyebrow.Meanwhile, some
The most sparse born hair, or due to burn, traffic accident, disease, infection, persistently make up, tatoo and the reason such as pressure and
Lose eyelash；In this context, when eyelashes can not play it prevent perspiration enter eyes or prevent eyes by sunlight,
During the functional characteristics of the invasion and attack of dust etc, people can meet with many inconvenience.
Eyelashes in the market increase product and mainly use the mascara of fiber or use the increasing of medicinal herb components
Long liquid, the former can only play role in decoration, and can not solve root problem, and the latter typically takes effect the slowest, it is difficult to meets consumption
The demand of person.Thus, offer one is provided badly and increases the significant eyelash growing liquid of eyelashes effect.
Summary of the invention
Present invention solves the technical problem that and be to provide a kind of eyelash growing liquid, the eyelash growing liquid eyelashes that the application provides
Increase effect notable.
In view of this, this application provides a kind of eyelash growing liquid, in terms of the percentage by weight of described eyelash growing liquid, by
Component A, component B form with component C:
Described component A includes:
Preservative 0.15～0.25%；
1,3 butylene glycol 0.60～1.0%；
Described component B includes:
Fuller olefinic carbon 60 .01～3%；
Palmityl hexapeptide-15 0.01～10%；
Water solublity VE 0.5～2%；
Described component C includes:
Preferably, in described component A, the content of preservative is 0.18wt%～0.22wt%, containing of described 1,3 butylene glycol
Amount is 0.8wt%～0.9wt%.
Preferably, the content of fullerene described in component B is 0.1wt%～2.5wt%.
Preferably, the content of described fullerene is 1.0wt%～2.0wt%.
Preferably, the content of described palmityl hexapeptide-15 is 1.5wt～9wt%.
Preferably, the content of described palmityl hexapeptide-15 is 3wt%～8wt%.
Preferably, the content of described water solublity VE is 0.8wt%～1.2wt%.
Preferably, the content of glycerol described in described component C is 2～8wt%, the content of allantoin be 0.10wt%～
0.15wt%, the content of described D-panthenol is 0.5wt%～1.0wt%.
Preferably, described preservative is chlorphenesin.
Present invention also provides the preparation method of described eyelash growing liquid, comprise the following steps:
After component C being heated, cooling adds component B, obtains the first mixture；
Add component A after heating after being lowered the temperature by described first mixture, cool down after mixing, obtain eyelash growing liquid；
Described component A includes:
Preservative 0.15～0.25%；
1,3 butylene glycol 0.60～1.0%；
Described component B includes:
Fuller olefinic carbon 60 .01～3%；
Palmityl hexapeptide-15 0.01～10%；
Water solublity VE 0.5～2%；
Described component C includes:
This application provides a kind of eyelash growing liquid, it includes component A, component B and component C, the wherein fowler in component B
Alkene can effectively eliminate ROS active oxygen, suppression sebum oxidation, promotes hair growth, and palmityl hexapeptide-15 can stimulate eyelashes angle
Protein gene, increases and increases thick eyelash；The application by using fullerene and palmityl hexapeptide-15 to compound, and with component A,
Component C cooperates, and the eyelash growing liquid enabling the application to provide dramatically increases promotion eyelashes and increases.
Detailed description of the invention
In order to be further appreciated by the present invention, below in conjunction with embodiment, the preferred embodiment of the invention is described, but
Should be appreciated that these describe simply as to further illustrate the features and advantages of the present invention rather than to the claims in the present invention
Limit.
The embodiment of the invention discloses a kind of eyelash growing liquid, in terms of the percentage by weight of described eyelash growing liquid, by group
A, component B is divided to form with component C:
Described component A includes:
Preservative 0.15～0.25%；
1,3 butylene glycol 0.60～1.0%；
Described component B includes:
Fuller olefinic carbon 60 .01～3%；
Palmityl hexapeptide-15 0.01～10%；
Water solublity VE 0.5～2%；
Described component C includes:
This application provides a kind of eyelash growing liquid, described eyelash growing liquid is by by fullerene and palmityl hexapeptide-15
Compound, enable the growth of eyelashes to take effect in 28 days.
Herein described eyelash growing liquid is made up of with component C component A, component B, and wherein component A includes:
Preservative 0.15～0.25wt%；
1,3 butylene glycol 0.60～1.0wt%.
The material that described preservative is well known to those skilled in the art, has no particular limits this application；Example,
Herein described preservative is preferably chlorphenesin, and the source of described chlorphenesin has no particular limits, and can be commercially available prod.
Described in described component A, the content of preservative is preferably 0.18wt%～0.22wt%, in an embodiment, and containing of described preservative
Amount is preferably 0.2w%.The content of described 1,3 butylene glycol is preferably 0.8wt%～0.9wt%, in an embodiment, and described 1,3-
The content of butanediol is preferably 0.8wt%.The source of described 1,3 butylene glycol is had no particular limits by the application, can be city
Sell product.
Component B in herein described eyelash growing liquid is key component, it include fullerene, palmityl hexapeptide-15 with
Water solublity VE.
Wherein, described fullerene trade name Radical Sponge, is Japan Vitamin C60BioResearch
The product of Corporation company.Described fullerene can effectively eliminate ROS active oxygen, suppression sebum oxidation, promotes that hair is raw
Long.
Described palmityl hexapeptide-15 is the safest a kind of victory peptide, it is possible to stimulates eyelashes keratin gene, increases and increase
Thick eyelash.
Described water solublity VE is that pure water is molten in water, its utilization that is easily absorbed by the body.
In described component B, the content of described fullerene is preferably 0.1～2.5wt%, in certain embodiments, described richness
The content strangling alkene is preferably 1.0wt%～2.0wt%, more preferably 1.2wt%～1.8wt%.Described palmityl hexapeptide-15
Content is preferably 1.5wt%～9wt%, in certain embodiments, the content of described palmityl hexapeptide-15 be preferably 3wt%～
8wt%, more preferably 4wt%～7wt%.The content of described water solublity VE is preferably 0.8wt%～1.2wt%.The application couple
Described fullerene, palmityl hexapeptide-15 have no particular limits with the source of water solublity VE.
Herein described component C includes glycerol, allantoin, D-panthenol and deionized water.
Wherein, described glycerol another name glycerol, it is a kind of liquid without the sweet clear and bright thickness of color and taste.Herein described glycerol
As solvent, its content is 1wt%～10wt%, in certain embodiments, the content of described glycerol be preferably 2wt%～
8wt%, more preferably 3wt%～5wt%.
Described allantoin another name Allantoin, it is a kind of hydantoin derivatives.Containing of herein described allantoin
Amount is preferably 0.10wt%～0.15wt%, and in certain embodiments, the content of described allantoin is preferably 0.15wt%.
Described D-panthenol is the precursor of vitamin B5, and it is the liquid of a kind of colourless to slightly yellow clear viscous.The application
The content of described D-panthenol is preferably 0.3wt%～1.2wt%, and in certain embodiments, the content of described D-panthenol is preferably
0.5wt%～1.0wt%.
Glycerol, allantoin in described component C have no particular limits with the source of D-panthenol, can be commercially available prod.
Present invention also provides the preparation method of described eyelash growing liquid, comprise the following steps:
After component C being heated, cooling adds component B, obtains the first mixture；
Add component A after heating after being lowered the temperature by described first mixture, cool down after mixing, obtain eyelash growing liquid；
Described component A includes:
Preservative 0.15～0.25%；
1,3 butylene glycol 0.60～1.0%；
Described component B includes:
Fuller olefinic carbon 60 .01～3%；
Palmityl hexapeptide-15 0.01～10%；
Water solublity VE 0.5～2%；
Described component C includes:
During obtaining the first mixture, the temperature of described heating is preferably 80～85 DEG C.Add component B it
Before, component C is preferably stirred by the application so that it is dissolve completely.The temperature of described cooling is preferably 45 DEG C～50 DEG C.
During obtaining eyelash growing liquid, the temperature of described first mixture cooling is preferably 40～45 DEG C, described
The temperature of component A after heating is preferably 60～65 DEG C, and the temperature of described cooling is preferably 30～35 DEG C.
The eyelash growing liquid compatibility that the present invention provides is simple, is compounded by fullerene and palmityl hexapeptide-15, increases and promote
The effect that eyelashes increase, test result indicate that, fullerene and palmityl hexapeptide-15 compound using effect and be better than and be used alone,
And this eyelash growing liquid preparation process is simple, it is not necessary to complicated machinery equipment, low cost.
In order to be further appreciated by the present invention, the eyelash growing liquid present invention provided below in conjunction with embodiment and preparation side thereof
Method is described in detail, and protection scope of the present invention is not limited by the following examples.
Embodiment 1
A, component C is heated to 80～85 DEG C, enables agitator simultaneously and be stirred with 100 revs/min, treat that it has dissolved
Entirely；
B, will dissolve component C completely and use cooling water temperature, and be cooled to 45～50 DEG C, be sequentially added into B component, stirring is all
Even；
C, treat that temperature drops to 40 DEG C, add and be previously heated to 60～65 DEG C of component A being uniformly dissolved, after stirring, cold
But to 35 DEG C of dischargings,.
The content data table of the component A of the present embodiment, B component component each with component C is as shown in table 1.
Embodiment 2
The preparation method of embodiment 2 is same as in Example 1, and difference is: in embodiment 2, the content of each component there occurs change
Changing, concrete component is as shown in table 1.
Embodiment 3
The preparation method of embodiment 3 is same as in Example 1, and difference is: in embodiment 3, the content of each component there occurs change
Changing, concrete component is as shown in table 1.
Comparative example 1
The preparation method of comparative example 1 is same as in Example 1, and difference is: in comparative example 1, the content of each component there occurs change
Changing, concrete component is as shown in table 1.
Comparative example 2
The preparation method of comparative example 2 is same as in Example 1, and difference is: in comparative example 2, the content of each component there occurs change
Changing, concrete component is as shown in table 1.
Table 1 embodiment 1～3 and the content data table (wt%) of each component in the eyelash growing liquid of comparative example 1～2 preparation
Embodiment 4
1, the physical and chemical index test result of comparative example and embodiment is as follows:
1) outward appearance: colourless transparent liquid；
2) pH value: 5.5-6.8；
3) heat-resistant stability investigates (48 DEG C × 24h): qualified；
4) cold-resistant study on the stability (-15 DEG C × 24h): qualified.
2, in order to prove effect of this product, determining that 50 female volunteers have carried out following test, the testing time is 4
In week, concrete test process is:
Subject Population: totally 50 (point 10 volunteers of 5 groups of each embodiments, do not have juxtaposition),
1) age is between 22 to 40 years old；
2) experimenter can be coordinated very well, regularity in one's life can be kept during studying；
Method of testing:
Comparative example 1, comparative example 2, embodiment 1, embodiment 2, embodiment 3 extract 10 volunteers respectively；Using method is:
Sooner or later, after face cleaning, screw out type brush, make hairbrush vertically upward, the most up brush from eyelashes root；Use 4 weeks continuously, before using
Measure in the eyelashes root (eyelashes at inner eye corner) of its upper eyelid eyelashes, eyelashes, eyelashes tail (eyelashes at the tail of the eye) length, use eyelash
Hair growth-promoting media one week, two weeks, three weeks, measure its upper eyelid eyelash length the most respectively after surrounding.
Test result:
This test sends 50 parts of sample altogether, and after the continuous surrounding of volunteer uses comparative example and embodiment, eyelashes increase feelings
Condition is as shown in table 2～6.
Table 2 uses the test case tables of data after the eyelash growing liquid that comparative example 1 provides
Table 3 uses the test case tables of data after the eyelash growing liquid that comparative example 2 provides
Table 4 uses the test case tables of data after the eyelash growing liquid that embodiment 1 provides
Table 5 uses the test case tables of data after the eyelash growing liquid that embodiment 2 provides
Table 6 uses the test case tables of data after the eyelash growing liquid that embodiment 3 provides
Interpretation
From above-mentioned test result, the eyelash growing liquid containing fullerene and palmityl hexapeptide-15 in the present invention makes
Effect is increased obvious with rear eyelashes, and, fullerene and palmityl hexapeptide-15 compound using effect and are better than and are used alone
Radical Sponge or palmityl hexapeptide-15.
The explanation of above example is only intended to help to understand method and the core concept thereof of the present invention.It is right to it should be pointed out that,
For those skilled in the art, under the premise without departing from the principles of the invention, it is also possible to the present invention is carried out
Some improvement and modification, these improve and modify in the protection domain also falling into the claims in the present invention.
Described above to the disclosed embodiments, makes professional and technical personnel in the field be capable of or uses the present invention.
Multiple amendment to these embodiments will be apparent from for those skilled in the art, as defined herein
General Principle can realize without departing from the spirit or scope of the present invention in other embodiments.Therefore, the present invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and principles disclosed herein and features of novelty phase one
The widest scope caused.
Claims (10)
1. an eyelash growing liquid, it is characterised in that in terms of the percentage by weight of described eyelash growing liquid, by component A, component B
Form with component C:
Described component A includes:
Preservative 0.15～0.25%；
1,3 butylene glycol 0.60～1.0%；
Described component B includes:
Fuller olefinic carbon 60 .01～3%；
Palmityl hexapeptide-15 0.01～10%；
Water solublity VE 0.5～2%；
Described component C includes:
Eyelash growing liquid the most according to claim 1, it is characterised in that in described component A, the content of preservative is
0.18wt%～0.22wt%, the content of described 1,3 butylene glycol is 0.8wt%～0.9wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that the content of fullerene described in component B is
0.1wt%～2.5wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that the content of described fullerene be 1.0wt%～
2.0wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that the content of described palmityl hexapeptide-15 is 1.5wt
～9wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that the content of described palmityl hexapeptide-15 is 3wt%
～8wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that the content of described water solublity VE be 0.8wt%～
1.2wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that the content of glycerol described in described component C be 2～
8wt%, the content of allantoin is 0.10wt%～0.15wt%, and the content of described D-panthenol is 0.5wt%～1.0wt%.
Eyelash growing liquid the most according to claim 1, it is characterised in that described preservative is chlorphenesin.
10. the preparation method of the eyelash growing liquid described in any one of claim 1～9, comprises the following steps:
After component C being heated, cooling adds component B, obtains the first mixture；
Add component A after heating after being lowered the temperature by described first mixture, cool down after mixing, obtain eyelash growing liquid；
Described component A includes:
Preservative 0.15～0.25%；
1,3 butylene glycol 0.60～1.0%；
Described component B includes:
Fuller olefinic carbon 60 .01～3%；
Palmityl hexapeptide-15 0.01～10%；
Water solublity VE 0.5～2%；
Described component C includes:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610613620.1A CN105997534A (en) | 2016-07-28 | 2016-07-28 | Eyelash increasing liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610613620.1A CN105997534A (en) | 2016-07-28 | 2016-07-28 | Eyelash increasing liquid and preparation method thereof |
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Family
ID=57115344
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| CN201610613620.1A Pending CN105997534A (en) | 2016-07-28 | 2016-07-28 | Eyelash increasing liquid and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107753356A (en) * | 2017-12-08 | 2018-03-06 | 中山市美源化妆品有限公司 | One kind promotes eyelash growing liquid formula |
| CN111388343A (en) * | 2020-03-16 | 2020-07-10 | 广州市熊本生物科技有限公司 | Eyelash softener and preparation method thereof |
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| CN1753968A (en) * | 2003-01-27 | 2006-03-29 | 三菱商事株式会社 | Antioxidative composition and composition for external use |
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| CN107753356A (en) * | 2017-12-08 | 2018-03-06 | 中山市美源化妆品有限公司 | One kind promotes eyelash growing liquid formula |
| CN111388343A (en) * | 2020-03-16 | 2020-07-10 | 广州市熊本生物科技有限公司 | Eyelash softener and preparation method thereof |
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Application publication date: 20161012 |