CN105963672A - Radix angelica sinensis and dried tangerine peel chewable tablet rich in soybean protein and preparation method of chewable tablet - Google Patents
Radix angelica sinensis and dried tangerine peel chewable tablet rich in soybean protein and preparation method of chewable tablet Download PDFInfo
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- 108010073771 Soybean Proteins Proteins 0.000 title claims abstract description 22
- 235000019710 soybean protein Nutrition 0.000 title claims abstract description 22
- 239000007910 chewable tablet Substances 0.000 title claims abstract description 19
- 229940068682 chewable tablet Drugs 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims description 7
- 241000382455 Angelica sinensis Species 0.000 title abstract 5
- 241000675108 Citrus tangerina Species 0.000 title abstract 5
- 239000000843 powder Substances 0.000 claims abstract description 28
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 14
- 229920001661 Chitosan Polymers 0.000 claims abstract description 13
- 239000004005 microsphere Substances 0.000 claims abstract description 8
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 7
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 7
- 229930195725 Mannitol Natural products 0.000 claims abstract description 7
- 241000237502 Ostreidae Species 0.000 claims abstract description 7
- 241000209140 Triticum Species 0.000 claims abstract description 7
- 235000021307 Triticum Nutrition 0.000 claims abstract description 7
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 7
- 239000000594 mannitol Substances 0.000 claims abstract description 7
- 235000010355 mannitol Nutrition 0.000 claims abstract description 7
- 235000020636 oyster Nutrition 0.000 claims abstract description 7
- 235000015067 sauces Nutrition 0.000 claims abstract description 7
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 7
- 239000000661 sodium alginate Substances 0.000 claims abstract description 7
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- 241000125175 Angelica Species 0.000 claims description 35
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 9
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- 239000011324 bead Substances 0.000 claims description 6
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- 238000003756 stirring Methods 0.000 claims description 6
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- 238000000855 fermentation Methods 0.000 claims description 4
- 230000004151 fermentation Effects 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 3
- 240000001046 Lactobacillus acidophilus Species 0.000 claims description 3
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims description 3
- 239000001888 Peptone Substances 0.000 claims description 3
- 108010080698 Peptones Proteins 0.000 claims description 3
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- 208000007502 anemia Diseases 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
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- QYZBCWXZSYTIOY-UHFFFAOYSA-N Mercuric oxide Chemical compound [O-2].[Hg+2] QYZBCWXZSYTIOY-UHFFFAOYSA-N 0.000 description 1
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- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The invention discloses a radix angelica sinensis and dried tangerine peel chewable tablet rich in soybean protein. The tablet is prepared from, by weight, 60-70 parts of radix angelica sinensis, 20-25 parts of dried tangerine peel, 15-18 parts of soybean protein powder, 6-8 parts of wheat gern powder, 2-4 parts of white nut powder, 1.3-1.6 parts of perila seed powder, 2.4-2.8 parts of oyster sauce, 6-8 parts of Amaranthus viridis, 3.6-4.4 parts of rape flower, 7-10 parts of papaya, 8-10 parts of mannitol, 6-8 parts of magnesium stearate, 50-60 parts of chitosan and a proper amount of sodium alginate solution. The chewable tablet prepared by combining radix angelica sinensis and dried tangerine peel is good in blood enriching effect and can be conveniently taken by anemia people in anemia symptoms, and injuries caused by anemia are reduced; when radix angelica sinensis and dried tangerine peel are fermented to prepare ferment, the medicine effect can be enhanced, and the tablet can be rapidly absorbed easily; the tablet is wrapped in a microsphere, so irritant odor and taste of the tablet can be effectively covered, and the tablet can be easily taken.
Description
Technical field
The present invention relates to food processing technology field, particularly relate to a kind of angelica and dried orange peel chewable tablet rich in soybean protein and preparation method thereof.
Background technology
Radix Angelicae Sinensis, for the dry root of umbelliferae angelica.Main product the southeast of Gansu, is secondly that Yunnan, Sichuan, Shaanxi, Hubei etc. save, is cultivation.There is replenishing and activating blood, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.It is usually used in blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis weighs due to its sweet in the mouth, therefore specially can enrich blood, and its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, has benefit in row, is the panacea enriched blood of circulation of qi promoting.
Pericarpium Citri Reticulatae is conventional Chinese medicine, has regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm.Ming Dynasty's Li Shizhen (1518-1593 A.D.) cloud: " then mend with tonic, then rush down with cathartic, then rise with Hydrargyri Oxydum Rubrum, then drop with fall medicine.Spleen is the mother of Primordial Qi, is the label taking the photograph gas, therefore Pericarpium Citri tangerinae is two through the medicine of edema caused by disorder of QI, but with join and reinforcing and reducing lift also." Pericarpium Citri Reticulatae can significantly reduce blood fat, significantly alleviates hepatocellular esterified degree, there are obvious blood fat reducing, prevention of arterial hardening and anti-high blood coagulation state effect, and Pericarpium Citri Reticulatae can suppress platelet aggregation, and there is reduction erythrocyte aggregation.
Anemia refers to that human peripheral blood erythrocyte volume reduces, less than a kind of common clinical symptoms of lower limit normal range.Pericarpium Citri Reticulatae and Radix Angelicae Sinensis collocation have effect of well enriching blood, and daily can have some improvement anemia.But owing to inconvenience taken by Chinese medicine, need to be processed making it easy to carry and take to them.The chewable tablet occurred on market can meet requirement, therefore they can be made chewable tablet, the most easy to carry, conveniently takes, and can quantitatively take, it is to avoid disposably takes and damage human body too much.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of angelica and dried orange peel chewable tablet rich in soybean protein and preparation method thereof.
The present invention is achieved by the following technical solutions:
A kind of angelica and dried orange peel chewable tablet rich in soybean protein, is made up of the raw material of following weight portion: Radix Angelicae Sinensis 60-70, Pericarpium Citri Reticulatae 20-25, soybean protein powder 15-18, wheat germ powder 6-8, white kernel powder 2-4, Fructus Perillae powder 1.3-1.6, Oyster sauce 2.4-2.8, Herba amaranthi ascendentis 6-8, rape flower 3.6-4.4, Fructus Chaenomelis 7-10, mannitol 8-10, magnesium stearate 6-8, chitosan 50-60, sodium alginate soln are appropriate.
The preparation method of described a kind of angelica and dried orange peel chewable tablet rich in soybean protein, comprises the following steps:
(1) the soak by water 60-70min of 5-6 times is added after Radix Angelicae Sinensis, Pericarpium Citri Reticulatae being cleaned together, after filtration, medicinal residues are pulverized standby, filtrate adds ethanol stirring after being concentrated into the 20-30% of volume be 65-70% to alcohol content, take supernatant after standing 20-24h and reclaim ethanol, after spray drying, obtain angelica and dried orange peel water extract；
(2) it is ground into 40-50 mesh after draining moisture after Herba amaranthi ascendentis, rape flower, Fructus Chaenomelis being cleaned roguing, the water of the weight such as addition and the peptone of 2-3%, through 110-120 DEG C of autoclave sterilization 25-30min, then first regulating mixture pH after being cooled to 35-37 DEG C is 5.5-6, then the bacillus acidophilus after overactivation accessing 4-5% is fermented 20-25h, then the medicinal residues adding angelica and dried orange peel continue fermentation 8-12h, and dried ultramicronising is pulverized and obtained angelica and dried orange peel ferment；
(3) add chitosan in 1% acetum of certain mass and dissolve, then with after sodium hydroxide solution regulation pH to 6.0, obtain chitosan solution standby, angelica and dried orange peel ferment is added in the sodium alginate soln of appropriate 15g/L and dissolve, it is then added in certain density calcium chloride solution, continuously stirred 25-30min, bead is collected after filtration, bead is put in chitosan solution, continuously stirred crosslinking 50-60min, at a temperature of 40 DEG C, it is dried 20-24h after sucking filtration washing, obtains angelica and dried orange peel ferment microsphere；
(4) angelica and dried orange peel ferment microsphere, the water extract of angelica and dried orange peel, soybean protein powder, wheat germ powder, white kernel powder, Fructus Perillae powder, Oyster sauce, mannitol co-grinding are crossed 60 mesh sieves, it is subsequently adding the water of 10% weight portion, stir and be placed in the vacuum drying oven of 55-65 DEG C that to be dried to water content be 2.5-3.5%, obtain mixing soft material；
(5) will mix after soft material is pulverized and cross 14-18 mesh sieve, and be subsequently adding magnesium stearate, after mix homogeneously, carry out tabletting, obtain the angelica and dried orange peel chewable tablet rich in soybean protein.
The invention have the advantage that the present invention is by making chewable tablet and have, by Radix Angelicae Sinensis and Pericarpium Citri Reticulatae combination, effect of well enriching blood, anemia crowd can be made conveniently to take when Anemia, reduce its harm brought, angelica and dried orange peel is made ferment by fermentation and can strengthen drug effect, contribute to quickly absorbing, it is wrapped in microsphere and can effectively be covered its irritating abnormal smells from the patient and mouthfeel, be conducive to taking.The raw materials such as the soybean protein of interpolation, Fructus Tritici aestivi contain rich in protein and other nutrient substance, supplement needed by human body.
Detailed description of the invention
A kind of angelica and dried orange peel chewable tablet rich in soybean protein, is made up of the raw material of following weight portion (kg): Radix Angelicae Sinensis 60, Pericarpium Citri Reticulatae 20, soybean protein powder 15, wheat germ powder 6, white kernel powder 2, Fructus Perillae powder 1.3, Oyster sauce 2.4, Herba amaranthi ascendentis 6, rape flower 3.6, Fructus Chaenomelis 7, mannitol 8, magnesium stearate 6, chitosan 50, sodium alginate soln are appropriate.
The preparation method of described a kind of angelica and dried orange peel chewable tablet rich in soybean protein, comprises the following steps:
(1) the soak by water 60min of 5 times is added after Radix Angelicae Sinensis, Pericarpium Citri Reticulatae being cleaned together, after filtration, medicinal residues are pulverized standby, filtrate be concentrated into volume 20% after to add ethanol stirring be 65% to alcohol content, stand and take supernatant after 20h and reclaim ethanol, after spray drying, obtain angelica and dried orange peel water extract；
(2) it is ground into 40 mesh after draining moisture after Herba amaranthi ascendentis, rape flower, Fructus Chaenomelis being cleaned roguing, the water of the weight such as addition and the peptone of 2%, through 110 DEG C of autoclave sterilization 25min, then first regulating mixture pH after being cooled to 35 DEG C is 5.5, then access the bacillus acidophilus after overactivation of 4% to ferment 20h, then the medicinal residues adding angelica and dried orange peel continue fermentation 8h, and dried ultramicronising is pulverized and obtained angelica and dried orange peel ferment；
(3) add chitosan in 1% acetum of certain mass and dissolve, then with after sodium hydroxide solution regulation pH to 6.0, obtain chitosan solution standby, angelica and dried orange peel ferment is added in the sodium alginate soln of appropriate 15g/L and dissolve, it is then added in certain density calcium chloride solution, continuously stirred 25min, bead is collected after filtration, bead is put in chitosan solution, continuously stirred crosslinking 50min, at a temperature of 40 DEG C, it is dried 20h after sucking filtration washing, obtains angelica and dried orange peel ferment microsphere；
(4) angelica and dried orange peel ferment microsphere, the water extract of angelica and dried orange peel, soybean protein powder, wheat germ powder, white kernel powder, Fructus Perillae powder, Oyster sauce, mannitol co-grinding are crossed 60 mesh sieves, it is subsequently adding the water of 10% weight portion, stir and be placed in the vacuum drying oven of 55 DEG C that to be dried to water content be 2.5%, obtain mixing soft material；
(5) will mix after soft material is pulverized and cross 14 mesh sieves, and be subsequently adding magnesium stearate, after mix homogeneously, carry out tabletting, obtain the angelica and dried orange peel chewable tablet rich in soybean protein.
Claims (2)
1. the angelica and dried orange peel chewable tablet rich in soybean protein, it is characterized in that, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 60-70, Pericarpium Citri Reticulatae 20-25, soybean protein powder 15-18, wheat germ powder 6-8, white kernel powder 2-4, Fructus Perillae powder 1.3-1.6, Oyster sauce 2.4-2.8, Herba amaranthi ascendentis 6-8, rape flower 3.6-4.4, Fructus Chaenomelis 7-10, mannitol 8-10, magnesium stearate 6-8, chitosan 50-60, sodium alginate soln are appropriate.
The preparation method of a kind of angelica and dried orange peel chewable tablet rich in soybean protein the most according to claim 1, it is characterised in that comprise the following steps:
(1) the soak by water 60-70min of 5-6 times is added after Radix Angelicae Sinensis, Pericarpium Citri Reticulatae being cleaned together, after filtration, medicinal residues are pulverized standby, filtrate adds ethanol stirring after being concentrated into the 20-30% of volume be 65-70% to alcohol content, take supernatant after standing 20-24h and reclaim ethanol, after spray drying, obtain angelica and dried orange peel water extract；
(2) it is ground into 40-50 mesh after draining moisture after Herba amaranthi ascendentis, rape flower, Fructus Chaenomelis being cleaned roguing, the water of the weight such as addition and the peptone of 2-3%, through 110-120 DEG C of autoclave sterilization 25-30min, then first regulating mixture pH after being cooled to 35-37 DEG C is 5.5-6, then the bacillus acidophilus after overactivation accessing 4-5% is fermented 20-25h, then the medicinal residues adding angelica and dried orange peel continue fermentation 8-12h, and dried ultramicronising is pulverized and obtained angelica and dried orange peel ferment；
(3) add chitosan in 1% acetum of certain mass and dissolve, then with after sodium hydroxide solution regulation pH to 6.0, obtain chitosan solution standby, angelica and dried orange peel ferment is added in the sodium alginate soln of appropriate 15g/L and dissolve, it is then added in certain density calcium chloride solution, continuously stirred 25-30min, bead is collected after filtration, bead is put in chitosan solution, continuously stirred crosslinking 50-60min, at a temperature of 40 DEG C, it is dried 20-24h after sucking filtration washing, obtains angelica and dried orange peel ferment microsphere；
(4) angelica and dried orange peel ferment microsphere, the water extract of angelica and dried orange peel, soybean protein powder, wheat germ powder, white kernel powder, Fructus Perillae powder, Oyster sauce, mannitol co-grinding are crossed 60 mesh sieves, it is subsequently adding the water of 10% weight portion, stir and be placed in the vacuum drying oven of 55-65 DEG C that to be dried to water content be 2.5-3.5%, obtain mixing soft material；
(5) will mix after soft material is pulverized and cross 14-18 mesh sieve, and be subsequently adding magnesium stearate, after mix homogeneously, carry out tabletting, obtain the angelica and dried orange peel chewable tablet rich in soybean protein.
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| CN201610371739.2A CN105963672A (en) | 2016-05-31 | 2016-05-31 | Radix angelica sinensis and dried tangerine peel chewable tablet rich in soybean protein and preparation method of chewable tablet |
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| CN201610371739.2A CN105963672A (en) | 2016-05-31 | 2016-05-31 | Radix angelica sinensis and dried tangerine peel chewable tablet rich in soybean protein and preparation method of chewable tablet |
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Application publication date: 20160928 |