CN105963345A - Composition for treating ichthyophthiriasis of loaches - Google Patents
Composition for treating ichthyophthiriasis of loaches Download PDFInfo
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- CN105963345A CN105963345A CN201610550603.8A CN201610550603A CN105963345A CN 105963345 A CN105963345 A CN 105963345A CN 201610550603 A CN201610550603 A CN 201610550603A CN 105963345 A CN105963345 A CN 105963345A
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- herba
- ichthyophthiriasis
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- misgurni anguillicaudati
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/20—Aceraceae (Maple family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
Abstract
The invention belongs to the field of aquaculture, and particularly discloses a composition for treating ichthyophthiriasis of loaches. The composition is prepared from the following components in parts by mass: 14-16 parts of croton tiglium leaves, 7-10 parts of thymus altaicus, 6-8 parts of longspike uraria and 4-6 parts of polystichum braunii. The composition can be used for curing loaches with ichthyophthiriasis, and does not stimulate affected loaches.
Description
Technical field
The present invention relates to aquaculture field, be specifically related to a kind of compositions treating Misgurni anguillicaudati ichthyophthiriasis.
Background technology
Misgurni anguillicaudati is high protein, low fat, food low in calories, vitamin b race rich content, the effect that vitamin b race is main
It is the Maintenance Of Skin Health, facilitating digestion, safeguards nervous system health etc..Sodium, potassium maintain the normal activities of cell jointly,
Containing substantial amounts of sodium in Sal, cause sodium in people's daily life to take in too much, the absorption relative deficiency of potassium, this just destroy sodium,
Potassium balance, Misgurni anguillicaudati is the food of hyperkalemia hyponatremia, and edible Misgurni anguillicaudati can regulate the balance of internal sodium, potassium.Misgurni anguillicaudati is possibly together with abundant
Ferrum, zinc, selenium.Ferrum is erythrocytic ingredient, can strengthen the band oxygen ability of blood.Zinc can protect skin health, increases
Strong man's body immunity function.Selenium is the mineral of a kind of Wheat Protein, it is particularly possible to prevention of liver disease.Misgurni anguillicaudati also has tonification spleen
Kidney, diuretic, effect of removing toxic substances.Main insufficiency of the spleen dysentery, calentura is thirsty, quenches one's thirst, infantile night sweat edema, dysuria, and male sexuality is not
Lift, viral hepatitis, hemorrhoid, furuncle, skin pruritus etc..The price of Misgurni anguillicaudati grows steadily, and loach breeding has extensively at home
Wealthy market prospect.
The performance of Misgurni anguillicaudati ichthyophthiriasis is: the sick skin of loach, fin, the gill, oral cavity etc. are covered with small particles, and naked eyes are visible, therefore again
Claim ichthyophthiriasis.When being in a bad way, body surface seemingly has one layer of white film, and scale comes off, and fin ray splits, rots.Sick fish body colour
Turn black, become thin, travelling slow, frequently rub on other objects, the most i.e. peel off death.Little melonworm does not has the age to spinal column
Select, all encroached on by it from loach Seedling to adult fish.Ichthyophthiriasis is that loach Seedling then, loach kind are endangered one of the most serious disease.
Major Epidemic is in the end of spring and the beginning of summer.Sick fish skin skin, fin, gill etc. have small particles, during microscopy, and polypide shape of a hoof macronucleus highly significant.
Traditional prevention and controls has: 1. quick lime is thoroughly cleaned up the pond, and kills the cyst of little melonworm.2. before putting fingerling in a suitable place to breed, if being found to have
Little melonworm, every cubic metre of water body adds people's 250mL formalin, embathes 15-20min.3. with the full pool of methylene blue 1-3mg/L
Splash, splashed every 4 days 1 time, be used in conjunction 3 times.4. the every mu every meter depth of water, uses Fructus Capsici powder 250g, Rhizoma Zingiberis Recens dry tablet or fresh
Rhizoma Zingiberis Recens 500g, mixing and water adding 10Kg boil, and are boiled into peppery ginger decoction, full pool spilling head after cooling, once a day, and continuous 3 times,
Fine day is splashed noon.
Formalin, methylene blue used in above method all have bio-toxicity, peppery ginger decoction also to have strong impulse, are killing
Go out while little melonworm, Misgurni anguillicaudati is also had pessimal stimulation.It is badly in need of a treatment Misgurni anguillicaudati little melon non-stimulated to Misgurni anguillicaudati in the market
The compositions of parasitosis.
Summary of the invention
It is an object of the invention to provide a kind of compositions treating Misgurni anguillicaudati ichthyophthiriasis, said composition is possible not only to cure suffers from little melon
The sick loach of parasitosis, and non-stimulated to sick loach.
For reaching above-mentioned purpose, the base case of the present invention is: a kind of compositions treating Misgurni anguillicaudati ichthyophthiriasis, according to mass parts
Number meter, including Folium Crotonis 14-16 part, mulch film perfume (or spice) 7-10 part, Herba urariae macrostachyae 6-8 part, Herba Polystichi Braunii 4-6 part.
Folium Crotonis has treating malaria disease, skin ulcer tinea, traumatic injury, effect of snakebite.Mulch film perfume (or spice) has a heat-clearing and toxic substances removing, relieving stranguria by diuresis,
Effect of parasite killing;Main cold cough, laryngopharynx swelling and pain, the puckery pain of pyretic stranguria, sore and toxic, depulization louse mosquito.Herba urariae macrostachyae has heat clearing away
Reduce phlegm, cooling blood for hemostasis, effect of parasite killing;For catching a cold, cough, malaria, filaricide, infantile malnutrition, spit blood, spitting of blood,
Hematuria.Herba Polystichi Braunii enters lung, spleen channel;There is effect of heat-clearing and toxic substances removing;Cure the disease poison dermexanthesis.
The program have the beneficial effect that one be have parasite killing removing toxic substances effect, both can kill little melonworm, non-stimulated to Misgurni anguillicaudati again
Effect.Two is to regulate Misgurni anguillicaudati homoiostasis, improves the resistance of Misgurni anguillicaudati;Three is that Herba Polystichi Braunii enters lung meridian, lung governing skin and hair,
The healing of damaged skin can be accelerated.
Prioritization scheme one: the optimization as to base case: according to mass fraction meter, also includes Herba Anaphalidis 10-12 part, greatly
JIUGUNIU 6-8 part.The total liquid of Herba Anaphalidis decocting is in vitro to golden yellow and Staphylococcus albus, sonne bacillus, typhoid fever
Bacillus, Salmonella paratyphi, escherichia coli etc. all have inhibitory action in various degree, Herba Anaphalidis ethanol extraction to have the most internal
Anti-infectious function.Radix Dobineae Delavayi has antiinflammatory, pain relieving, cough-relieving, drives effect of sore away;Control cough due to lung-heat, mastitis, the parotid gland
Inflammation, ulcerative carbuncle.This programme adds effect of bactericidal antiphlogistic, it is to avoid the secondary infection wounds such as antibacterial.
Prioritization scheme two: the optimization as to prioritization scheme one: according to mass fraction meter, also includes Herba Sidae Rhombifoliae 5-7 part, ground Fructus Persicae
Flower 2-3 part.Herba Sidae Rhombifoliae has refrigerant drawing out pus by applying a plaster to the affected part, effect of detumescence and apocenosis.Radix Urenae Lobatae has expelling wind and activating blood circulation, clearing away heat-damp and promoting diuresis, removing toxic substances
Effect of detumescence.This programme adds effect of evacuation of pus granulation promoting, may advantageously facilitate wound healing.
Prioritization scheme three: the optimization as to prioritization scheme two: according to mass fraction meter, is by Folium Crotonis 15 parts, mulch film perfume (or spice) 9
Part, Herba urariae macrostachyae 7 parts, Herba Polystichi Braunii 5 parts, Herba Anaphalidis 11 parts, Radix Dobineae Delavayi 7 parts, Herba Sidae Rhombifoliae 6 parts, Radix Urenae Lobatae 2.4
Part, Herba Orchidis Latifoliae 4 parts composition.Herba Orchidis Latifoliae has heart tonifying, the kidney invigorating, promotes the production of body fluid, and quenches the thirst, effect of strengthening the spleen and stomach;Main agitation is thirsty,
Anorexia.This programme can increase the food ration of Misgurni anguillicaudati, thus swallows more compositions, is conducive to shortening the course of disease.
Detailed description of the invention
Below by detailed description of the invention, the present invention is further detailed explanation:
9 box for breeding of Setup Experiments, are divided into 9 groups, often 1 box for breeding of group, and the size of each box for breeding is 1m × 1m × 1m,
It is placed with fine sand and a little water plant in case, ventilates in right amount.Misgurni anguillicaudati (the body suffering from ichthyophthiriasis at the beginning of 80 tails is put in a suitable place to breed in each box for breeding
The number of table small particles is between 20-35), divided by lower process difference outside, other treatment conditions are the most identical:
Blank group: feedstuff of only throwing something and feeding, does not use any medicine.
Matched group: using Fructus Capsici powder 0.4g, fresh ginger 0.8g, add water 15g, and intense fire boils, and slow fire endures 25min, obtains peppery Rhizoma Zingiberis Recens
Soup, after cooling, full case is splashed, and once a day, continuous 3 times, fine day is splashed noon.
Experiment A group to experiment G group compositions will add the water of 3 times of volumes, intense fire boils, and slow fire endures 25min, obtain medicinal liquid with
Medicinal residues.The full case of medicinal liquid is splashed, 0.5L/ case, and once a day, continuous 3 times, fine day is splashed noon.Powder beaten by the medicinal residues of compositions,
Medicinal residues are admixed in feedstuff and throws something and feeds, be used in conjunction 3 days;Medicinal residues and quality of the fodder are than for 1:4.
Experiment A group: compositions, according to mass fraction meter, is by Folium Crotonis 14 parts, fragrant 10 parts of mulch film, Herba urariae macrostachyae 6 parts, cloth
Bright polystichun 4 parts composition.
Experiment B group: compositions, according to mass fraction meter, is by Folium Crotonis 16 parts, fragrant 7 parts of mulch film, Herba urariae macrostachyae 8 parts, cloth
Bright polystichun 6 parts composition.
Experiment C group: compositions, according to mass fraction meter, is by Folium Crotonis 14.8 parts, fragrant 8 parts of mulch film, Herba urariae macrostachyae 6.5 parts,
Herba Polystichi Braunii 4.4 parts, Herba Anaphalidis 10 parts, Radix Dobineae Delavayi 8 parts composition.
Experiment D group: compositions, according to mass fraction meter, is by Folium Crotonis 14.2 parts, fragrant 7.4 parts of mulch film, Herba urariae macrostachyae 7.5 parts,
Herba Polystichi Braunii 5.8 parts, Herba Anaphalidis 12 parts, Radix Dobineae Delavayi 6 parts composition.
Experiment E group: compositions, according to mass fraction meter, is by Folium Crotonis 15.6 parts, fragrant 8.7 parts of mulch film, Herba urariae macrostachyae 7.1 parts,
Herba Polystichi Braunii 4.7 parts, Herba Anaphalidis 10.6 parts, Radix Dobineae Delavayi 6.3 parts, Herba Sidae Rhombifoliae 5 parts, Radix Urenae Lobatae 2 parts composition.
Experiment F group: compositions, according to mass fraction meter, is by Folium Crotonis 15.3 parts, fragrant 9.2 parts of mulch film, Herba urariae macrostachyae 6.2 parts,
Herba Polystichi Braunii 5.2 parts, Herba Anaphalidis 11.2 parts, Radix Dobineae Delavayi 7.8 parts, Herba Sidae Rhombifoliae 7 parts, Radix Urenae Lobatae 3 parts composition.
Experiment G group: compositions, according to mass fraction meter, is by Folium Crotonis 15 parts, fragrant 9 parts of mulch film, Herba urariae macrostachyae 7 parts, cloth
Bright polystichun 5 parts, Herba Anaphalidis 11 parts, Radix Dobineae Delavayi 7 parts, Herba Sidae Rhombifoliae 6 parts, Radix Urenae Lobatae 2.4 parts, Herba Orchidis Latifoliae 4 parts composition
's.
After 5 days, experimental result is as follows:
Blank group | Matched group | Experiment A group | Experiment B group | Experiment C group | Experiment D group | Experiment E group | Experiment F group | Experiment G group | |
Cure (tail) | 0 | 57 | 67 | 70 | 73 | 72 | 76 | 75 | 78 |
Take a turn for the better (tail) | 0 | 20 | 13 | 10 | 7 | 8 | 4 | 5 | 2 |
Dead (tail) | 47 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Result is added up:
Blank group: cure rate 0, improvement rate 0, mortality rate 58.8%.
Matched group: cure rate 71.3%, improvement rate 25.0%, mortality rate 3.7%.
Experiment A group: cure rate 83.8%, improvement rate 16.2%, mortality rate 0.
Experiment B group: cure rate 87.5%, improvement rate 12.5%, mortality rate 0.
Experiment C group: cure rate 91.3%, improvement rate 8.7%, mortality rate 0.
Experiment D group: cure rate 90.0%, improvement rate 10.0%, mortality rate 0.
Experiment E group: cure rate 95.0%, improvement rate 5.0%, mortality rate 0.
Experiment F group: cure rate 93.8%, improvement rate 6.2%, mortality rate 0.
Experiment G group: cure rate 97.5%, improvement rate 2.5%, mortality rate 0.
Interpretation of result: blank group, owing to not applying medicine, causes Misgurni anguillicaudati mortality.Matched group uses peppery ginger decoction, can kill
Go out little melonworm, for treatment Misgurni anguillicaudati ichthyophthiriasis, there is certain effect, but owing to its drug effect is mainly in water body, do not have
In feedstuff, add medicine, thus cure rate to compare the present invention relatively low.After sprinkling peppery ginger decoction, the Misgurni anguillicaudati of matched group occurs restless,
In water, travelling speed is accelerated, and illustrates that peppery ginger decoction has stimulation to Misgurni anguillicaudati.
Experiment A group and B group are to have employed the base case of the present invention, and experiment C group is the base case used to experiment G group
Preferred version, the cure rate of these seven experimental grouies all significantly better than using the matched group of conventional solution, and does not has ill cause
Dead Misgurni anguillicaudati.After sprinkling medicinal liquid, experiment A group is acted normally to the Misgurni anguillicaudati of experiment G group, does not occur restless, it is seen that medicinal liquid pair
Misgurni anguillicaudati has no stimulation.As can be seen here, the present invention compared to existing technology, has prominent substantive distinguishing features and significantly progress.
Above-described is only embodiments of the invention, and in scheme, the known general knowledge such as using method and characteristic is too much retouched at this
State.It should be pointed out that, for a person skilled in the art, under the premise of not departing from the present invention, it is also possible to make some changing
Entering, these also should be considered as protection scope of the present invention, and these are all without affecting effect and the practical applicability that the present invention implements.
The protection domain that this application claims should be as the criterion with the content of its claim, and the detailed description of the invention in description etc. is recorded permissible
For explaining the content of claim.
Claims (4)
1. the compositions treating Misgurni anguillicaudati ichthyophthiriasis, it is characterised in that: according to mass fraction meter, including Folium Crotonis 14-16 part,
Mulch film perfume (or spice) 7-10 part, Herba urariae macrostachyae 6-8 part, Herba Polystichi Braunii 4-6 part.
A kind of compositions treating Misgurni anguillicaudati ichthyophthiriasis the most according to claim 1, it is characterised in that: according to mass fraction meter,
Also include Herba Anaphalidis 10-12 part, Radix Dobineae Delavayi 6-8 part.
A kind of compositions treating Misgurni anguillicaudati ichthyophthiriasis the most according to claim 2, it is characterised in that: according to mass fraction meter,
Also include Herba Sidae Rhombifoliae 5-7 part, Radix Urenae Lobatae 2-3 part.
A kind of compositions treating Misgurni anguillicaudati ichthyophthiriasis the most according to claim 3, it is characterised in that: according to mass fraction meter,
It is by Folium Crotonis 15 parts, fragrant 9 parts of mulch film, Herba urariae macrostachyae 7 parts, Herba Polystichi Braunii 5 parts, Herba Anaphalidis 11 parts, big nine strands
Cattle 7 parts, Herba Sidae Rhombifoliae 6 parts, Radix Urenae Lobatae 2.4 parts, Herba Orchidis Latifoliae 4 parts composition.
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CN201610550603.8A CN105963345A (en) | 2016-07-13 | 2016-07-13 | Composition for treating ichthyophthiriasis of loaches |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103877459A (en) * | 2012-12-20 | 2014-06-25 | 青岛中仁药业有限公司 | Compound Chinese herbal medicine capable of treating grass carp ichthyophthirius multifiliis and its production method |
CN104322418A (en) * | 2014-11-03 | 2015-02-04 | 苏修之 | Monopterus albus water tank aquaculture method capable of preventing Ichthyophthiriasis |
CN105327173A (en) * | 2015-11-19 | 2016-02-17 | 集美大学 | Chinese herbal medicine compound additive for preventing and treating fish parasite diseases and production method of Chinese herbal medicine compound additive |
-
2016
- 2016-07-13 CN CN201610550603.8A patent/CN105963345A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103877459A (en) * | 2012-12-20 | 2014-06-25 | 青岛中仁药业有限公司 | Compound Chinese herbal medicine capable of treating grass carp ichthyophthirius multifiliis and its production method |
CN104322418A (en) * | 2014-11-03 | 2015-02-04 | 苏修之 | Monopterus albus water tank aquaculture method capable of preventing Ichthyophthiriasis |
CN105327173A (en) * | 2015-11-19 | 2016-02-17 | 集美大学 | Chinese herbal medicine compound additive for preventing and treating fish parasite diseases and production method of Chinese herbal medicine compound additive |
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Application publication date: 20160928 |