CN105963266A - Glucose tablet and preparation method thereof - Google Patents
Glucose tablet and preparation method thereof Download PDFInfo
- Publication number
- CN105963266A CN105963266A CN201610306196.6A CN201610306196A CN105963266A CN 105963266 A CN105963266 A CN 105963266A CN 201610306196 A CN201610306196 A CN 201610306196A CN 105963266 A CN105963266 A CN 105963266A
- Authority
- CN
- China
- Prior art keywords
- glucose
- tablet
- vitis viniferae
- label
- fructus vitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
Abstract
The invention discloses a glucose tablet and a preparation method of the glucose tablet. The glucose tablet comprises a glucose tablet core, the glucose tablet core is internally and auxiliary filled with glucose powder, and the glucose tablet core is prepared from the following components in percentage: 80 to 95 percent of glucose which takes corn as a raw material, 2 to 3 percent of adhesive, 1 to 2 percent of microcrystalline cellulose, 4 to 5 percent of wetting agent, 0.1 to 0.3 percent of a lubricating agent and the like. According to the glucose tablet and the preparation method, disclosed by the invention, glucose is prepared into sugar particles, the carry is convenient, the raw materials are common and natural, the proportion is suitable, and higher safety and high absorbability are obtained.
Description
Technical field
The present invention relates to a kind of Fructus Vitis viniferae sugar-tablet and preparation method thereof.
Background technology
For diabetes patient, control feed and carbohydrate metabolism are the things that part is extremely difficult.Because self metabolism obstacles of blood glucose, or medication
Excessively, by doctor's advice the most arbitrarily do not add and subtract drug dose, it occur frequently that hypoglycemia.When hypoglycemia occurs, the heart can be directly resulted in
Angiopathy and disordered brain function.Hyperglycemia can cause complication, and severe hypoglycemia can threaten life at once.Hypoglycemia ratio
Hyperglycemia is more fearful.
A lot of diabetes patients are not aware that the hypoglycemia serious harm to human body, mistake think that blood glucose is the lowest more good, do not know yet
How to be effectively prevented from and to control hypoglycemia.When there is hypoglycemia, they usually alleviate this situation with the most common food,
Such as confection, laughable, fruit juice, cookies etc..These food contain sucrose or fructose, require time for resolving into glucose, this
Sample can postpone the lifting of blood glucose makes hypoglycemic symptom not improve in time, causes patient more to take food, and works as Hypoglycemic symptoms
During alleviation, blood glucose is the highest, causes blood glucose fluctuation very big, blood glucose the most so can be made to be more difficult to control.So, sugar friend is sending out
Glucose is preferably selected to correct during raw hypoglycemia.
Summary of the invention
The present invention seeks to: aim to provide a kind of Fructus Vitis viniferae sugar-tablet, be used for solving existing food resolves into the glucose time longer,
Hypoglycemic symptoms can not improve in time, causes blood glucose fluctuation big, the problem that blood glucose is more difficult to control.
For realizing above-mentioned technical purpose, the technical solution used in the present invention is as follows:
A kind of Fructus Vitis viniferae sugar-tablet, including glucose label, described glucose sheet in-core auxiliary glucose powder, described glucose label bag
Include the glucose with Semen Maydis as raw material, binding agent, microcrystalline Cellulose, wetting agent and lubricant.
Limiting further, each composition ratio of described glucose label is: the glucose 80%-95% of maize raw material, binding agent
2%-3%, microcrystalline Cellulose 1%-2%, wetting agent and lubricant 4%-5% and 0.1%-0.3% respectively.
Limiting further, described wetting agent is pure distilled water.
Limiting further, described lubricant is magnesium stearate or Stepanol MG.
Limit further, the preparation method of a kind of Fructus Vitis viniferae sugar-tablet, comprise the following steps:
Step one: Semen Maydis is made starch milk, to corn starch milk sterilized after add saccharogenic amylase and carry out saccharifying, be then passed through
The multiple working procedures such as enzyme denaturing decolorization filtering evaporative crystallization separation drying and crushing make the Portugal with Semen Maydis as primary raw material
Grape sugar-tablet core, and and place it in adiabatic drying, aseptic environment；Step 2: glucose powder is used the special stone roller of medicine
Broken machine crushed into powder, and place it in adiabatic drying, aseptic environment；Step 3: by each composition of glucose label
Proportionally take, first the glucose of maize raw material is stirred, add bonding by proportion the most successively and microcrystalline Cellulose continues
Continuous stirring mixing 3-5 minute, now keeps temperature 38-40 degree Celsius；Step 4: then press proportion and add wetting agent and lubrication
Agent etc., continue stirring 2-3 minute, and temperature is continually maintained in 38-40 degree Celsius；Step 5: by the material obtained by step 4
Carry out suitably putting into tablet machine after drying and be pressed into graininess, now the powder of step 2 gained is pressed into by tablet machine
Intragranular.
A kind of Fructus Vitis viniferae sugar-tablet of the present invention compared with prior art, has the advantages that the Fructus Vitis viniferae sugar-tablet of the present invention, system
Become the form of particulate sugar, easy to carry, and raw material is popular, natural, and proportioning is suitable, has higher safety, can absorb
Property, it is possible to help patient to regain one's strength, supplement energy quickly.
Accompanying drawing explanation
Nothing
Detailed description of the invention
In order to make those skilled in the art that the present invention be may be better understood, below in conjunction with embodiment, technical solution of the present invention is entered
One step explanation.
A kind of glucose coating of the present invention, including glucose label, glucose sheet in-core auxiliary glucose powder, glucose label
Including the glucose with Semen Maydis as raw material, binding agent, microcrystalline Cellulose, wetting agent and lubricant.
Preferably each composition ratio of glucose label is: the glucose 80%-95% of maize raw material, binding agent 2%-3%, microcrystalline cellulose
Element 1%-2%, wetting agent and lubricant 4%-5% and 0.1%-0.3% respectively.
Preferably wetting agent is distilled water.
Preferred emollient is magnesium stearate or Stepanol MG.
The preparation method of a kind of Fructus Vitis viniferae sugar-tablet of the present invention, comprises the following steps: step one: Semen Maydis is made starch milk, to jade
Add saccharogenic amylase after rice starch breast is sterilized and carry out saccharifying, be then passed through enzyme denaturing decolorization filtering evaporative crystallization and separate
The multiple working procedure such as drying and crushing makes the glucose label with Semen Maydis as primary raw material, and and place it in adiabatic drying,
Aseptic environment；Step 2: glucose powder is used medicine special crusher crushed into powder, and places it in the most dry
Dry, aseptic environment；Step 3: each composition of glucose label is proportionally taken, first the glucose to maize raw material
It is stirred, presses proportion the most successively and add bonding and microcrystalline Cellulose continuation stirring mixing 3-5 minute, now keep temperature
38-40 degree Celsius；Step 4: then pressing proportion and add wetting agent and lubricant etc., continue stirring 2-3 minute, temperature continues
It is maintained at 38-40 degree Celsius；Step 5: the material obtained by step 4 is carried out suitably puts into tablet machine after drying and is pressed into
Graininess, is now pressed into the powder of step 2 gained in granule by tablet machine.
The Fructus Vitis viniferae sugar-tablet of the present invention, has the advantages that the Fructus Vitis viniferae sugar-tablet of the present invention, makes the form of particulate sugar, carry
Convenient, and raw material is popular, natural, and proportioning is suitable, has higher safety, absorbability, it is possible to help quickly to suffer from
Person regains one's strength, supplements energy.
Above a kind of Fructus Vitis viniferae sugar-tablet that the present invention provides and preparation method thereof is described in detail.The explanation of specific embodiment is only
It is the method and core concept thereof being adapted to assist in and understanding the present invention.It should be pointed out that, those skilled in the art are come
Saying, under the premise without departing from the principles of the invention, it is also possible to the present invention is carried out some improvement and modification, these improve and modify
Also fall in the protection domain of the claims in the present invention.
Claims (5)
1. a Fructus Vitis viniferae sugar-tablet, it is characterised in that: include glucose label, described glucose sheet in-core auxiliary glucose powder, institute
State glucose label and include the glucose with Semen Maydis as raw material, binding agent, microcrystalline Cellulose, wetting agent and lubricant.
A kind of Fructus Vitis viniferae sugar-tablet the most according to claim 1, it is characterised in that: each composition ratio of described glucose label is:
The glucose 80%-95% of maize raw material, binding agent 2%-3%, microcrystalline Cellulose 1%-2%, wetting agent and lubricant 4%-5% respectively
And 0.1%-0.3%.
A kind of Fructus Vitis viniferae sugar-tablet the most according to claim 1, it is characterised in that: described wetting agent is distilled water.
A kind of Fructus Vitis viniferae sugar-tablet the most according to claim 1, it is characterised in that: described lubricant is magnesium stearate or 12
Alkylsurfuric acid magnesium.
5. according to the preparation method of the arbitrary described a kind of Fructus Vitis viniferae sugar-tablet of claim 1-4, it is characterised in that: comprise the following steps:
Step one: Semen Maydis is made starch milk, to corn starch milk sterilized after add saccharogenic amylase and carry out saccharifying, be then passed through enzyme denaturing
The multiple working procedures such as decolorization filtering evaporative crystallization separation drying and crushing make the glucose with Semen Maydis as primary raw material
Label, and and place it in adiabatic drying, aseptic environment；
Step 2: glucose powder is used medicine special crusher crushed into powder, and places it in adiabatic drying, aseptic ring
Border；
Step 3: each composition of glucose label is proportionally taken, first the glucose of maize raw material is stirred, then depends on
Secondary addition by proportion bonds and microcrystalline Cellulose continuation stirring mixing 3-5 minute, now holding temperature 38-40 degree Celsius；
Step 4: then pressing proportion and add wetting agent and lubricant etc., continue stirring 2-3 minute, temperature is continually maintained in 38-40 and takes the photograph
Family name's degree；
Step 5: the material obtained by step 4 is carried out suitably puts into tablet machine after drying and is pressed into graininess, now by step 2
The powder of gained is pressed in granule by tablet machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610306196.6A CN105963266A (en) | 2016-05-09 | 2016-05-09 | Glucose tablet and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610306196.6A CN105963266A (en) | 2016-05-09 | 2016-05-09 | Glucose tablet and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105963266A true CN105963266A (en) | 2016-09-28 |
Family
ID=56991473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610306196.6A Pending CN105963266A (en) | 2016-05-09 | 2016-05-09 | Glucose tablet and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105963266A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1900300A (en) * | 2006-07-20 | 2007-01-24 | 南京工业大学 | Low temperature saccharification process for corn powder |
| CN101096694A (en) * | 2007-07-16 | 2008-01-02 | 南京工业大学 | Maize flour low-temperature synchronous saccharification technique by double enzymatical process and its application |
| CN103981239A (en) * | 2014-05-13 | 2014-08-13 | 江南大学 | Method of improving saccharification product purity of high-concentration starch |
| CN105193760A (en) * | 2015-10-08 | 2015-12-30 | 北京康力基生物科技有限公司 | High-content glucosamine sulfate tablet and preparation method |
-
2016
- 2016-05-09 CN CN201610306196.6A patent/CN105963266A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1900300A (en) * | 2006-07-20 | 2007-01-24 | 南京工业大学 | Low temperature saccharification process for corn powder |
| CN101096694A (en) * | 2007-07-16 | 2008-01-02 | 南京工业大学 | Maize flour low-temperature synchronous saccharification technique by double enzymatical process and its application |
| CN103981239A (en) * | 2014-05-13 | 2014-08-13 | 江南大学 | Method of improving saccharification product purity of high-concentration starch |
| CN105193760A (en) * | 2015-10-08 | 2015-12-30 | 北京康力基生物科技有限公司 | High-content glucosamine sulfate tablet and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| WLKX12345: ""以淀粉为原料双酶法制葡萄糖生产工艺"", 《百度文库》 * |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160928 |
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| RJ01 | Rejection of invention patent application after publication |