CN105963156A - Pregnancy line massage lotion and method for preparing same - Google Patents

Pregnancy line massage lotion and method for preparing same Download PDF

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CN105963156A
CN105963156A CN 201610485100 CN201610485100A CN105963156A CN 105963156 A CN105963156 A CN 105963156A CN 201610485100 CN201610485100 CN 201610485100 CN 201610485100 A CN201610485100 A CN 201610485100A CN 105963156 A CN105963156 A CN 105963156A
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component
massage
water
2wt
ratio
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CN 201610485100
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妤煎姜
楼彪
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娇时日化(杭州)股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toilet preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/72Cosmetics or similar toilet preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/72Cosmetics or similar toilet preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toilet preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/96Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention discloses pregnancy line massage lotion. The pregnancy line massage lotion comprises first components, second components, third components and fourth components. The first components comprise water, disodium EDTA (ethylene diamine tetraacetic acid) and humectants; the second components comprise PEG-60 dehydrated sorbitol stearate and softening and wetting agents; the third components comprise water and acrylic acid (ester)/C10-30 alkyl alcohol acrylate cross-linked polymers; the fourth components comprise acetyl hexapeptide-8, acetyl tripeptide-30 melon amino acid and pentapeptide. The pregnancy line massage lotion has the advantage of effects of reducing the quality difference of products.

Description

孕纹按摩乳及其制备方法 Pregnancy massage milk lines and preparation method

技术领域 FIELD

[0001 ]本发明涉及护肤领域,特别涉及一种孕纹按摩乳及其制备方法。 [0001] The present invention relates to skin care field, particularly to a massage pattern pregnant milk and its preparation method.

背景技术 Background technique

[0002] 孕纹,指的是出现在皮肤过度膨胀和荷尔蒙变化之后的皮肤的条或带。 [0002] pregnancy pattern, refers to a strip of skin excessive expansion occurs after hormonal changes and skin or belt. 妇女在妊娠期间受荷尔蒙影响,腹部膨隆使皮肤的弹力纤维与胶原纤维因外力牵拉而受到不同程度的损伤或断裂,皮肤变薄变细,腹壁皮肤变薄变细,腹壁皮肤会出现一些宽窄不同、长短不一的粉红色或紫红色的波浪状花纹;分娩后,这些花纹会逐渐消失,留下白色或银白色的疤痕浅痕。 Women receiving hormonal influence during pregnancy, abdominal distension of the skin elastic fibers and collagen fibers due to external forces pulling been varying degrees of damage or breakage, thinning of the skin becomes thin, thin and small abdominal skin, the abdominal skin will be some width different, varying lengths of pink or purple wavy pattern; after delivery, these patterns will gradually disappear, leaving a white or silver scar light marks. 孕纹不容易消失,且其使妇女的皮肤出现松弛、褶皱、腹部脂肪堆积、乳房下坠等, 严重影响了妇女产后的体态和身心健康。 Pregnant grain is not easy to disappear, and the women of loose skin, wrinkles, accumulation of abdominal fat, breast falling, etc., seriously affecting the health of women and postpartum body. 目前行业内共同认为,孕纹的最佳处理时间是刚出现孕纹的怀孕期间;市面上也有大量处理孕纹的产品,其中采用精油来去除孕纹是常见的方式。 At present the industry's common that the best treatment time is pregnant grain patterns during pregnancy pregnant just appear; there are also a large number of pregnant grain processing products, including the use of essential oils to remove pregnant pattern is a common way.

[0003] 申请公布号为CN105534746A、申请公布日为2016年5月4日的中国专利公开了一种按摩用修复妊娠纹精油,其原料包括甜杏仁油、小麦胚芽油、香茅醛、安基苯甲酸甲酯、丝素肽、透明质酸、氨基酸、椰子胶原蛋白、橘子精油、乳香精油、橙花精油、熏衣草精油、柑橘精油、乳香精油和酪梨油。 [0003] Application Publication No. CN105534746A, Chinese patent application publication date of May 4, 2016 discloses a repair stretch marks massage oil, raw materials including sweet almond oil, wheat germ oil, citronella aldehyde, Kay benzoate, silk peptide, hyaluronic acid, amino acid, collagen, coconut, orange oil, frankincense, neroli oil, lavender oil, citrus oil, frankincense oil, and avocado.

[0004] 现有技术的不足之处在于,其采用相当量的不同精油来实现修复妊娠纹的目的, 然而这些精油存在易挥发的特点且不同精油的挥发程度不同,这将造成存放的产品品质不一,影响使用效果。 Deficiencies [0004] prior art in that it uses a considerable amount of different essential oils to achieve the purpose of repair stretch marks, but the presence of these volatile oils of different characteristics and different levels of volatile essential oils, which will cause the quality of stored products different, affect the results.

发明内容 SUMMARY

[0005] 本发明的第一目的是提供一种孕纹按摩乳,其解决了产品挥发引起的产品品质不一的问题,具有减少产品品质差异性的效果。 [0005] The first object of the present invention is to provide a massage milk pregnant pattern, which solves the problem of varying quality product volatilization products, with a reduced quality of product differentiation effects.

[0006] 本发明的上述技术目的是通过以下技术方案得以实现的: 一种孕纹按摩乳,包括第一组份、第二组份、第三组份和第四组份;其中, 所述第一组份包括水、EDTA二钠和保湿剂; 所述第二组份包括PEG-60失水山梨醇硬脂酸酯和柔润剂; 第三组份包括水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物; 所述第四组份包括乙酰基六肽-8、乙酰基三肽-30瓜氨酸和五肽。 [0006] The technical object of the present invention is achieved by the following technical solutions: A pregnancy massage milk lines, comprising a first component, a second component, the third component and the fourth component; wherein, said the first component comprises water, EDTA disodium, and humectants; the second component comprises PEG-60 sorbitan monostearate, and emollients; a third component comprising water and acrylic acid (acrylate) s / C10 -30 alkanol crosslinked acrylate polymer; the fourth component include acetyl hexapeptide -8, -30 tripeptide acetyl citrulline and pentapeptides.

[0007] 采用上述技术方案,乙酰基六肽-8、乙酰基三肽-30瓜氨酸和五肽结合作用,影响融泡复合体,减少囊泡释放神经递质的速度和释放量,从而减弱肌肉收缩,减少妊娠纹和皱纹的产生;同时其对受损肌肤进行营养补充,肌肤吸收后能改善并减少已有的妊娠纹;同时利用保湿剂和柔润剂,起到锁水和补水的目的,进一步改善肌肤状况; 本申请的技术方案中未采用精油这类挥发性物质,产品中各成分挥发可忽略不计,且本申请通过各成分之间的相互作用而进一步减少各成分挥发的可能性,使存放的产品品质稳定,确保使用效果。 [0007] With the above technical solution, acetyl hexapeptide -8, -30 acetyl citrulline and tripeptide pentapeptide binding, affect the melt bubble complex, reduction rate and release vesicles neurotransmitter release, thereby weakened muscle contraction, reduce stretch marks and wrinkles; while its damaged skin nutritional supplement, can improve the skin to absorb and reduce existing stretch marks; while taking advantage of moisturizer and emollient, moisturizing and replenishment of play purpose, to further improve skin condition; aspect of the present disclosure is not employed in the essential oil of such volatile substances, volatile components in the product is negligible, and the present application by the interaction between the components and the components to further reduce the possibility of volatilization , making the product quality and shelf-stable to ensure results.

[0008] 研究发现,按质量计,所述第一组份、第二组份、第三组份和第四组份的用量比为18~22:19~23:10~13:1; 所述第一组份中,水、EDTA二钠和保湿剂的用量比为1:0.1 %~0.2% :0.25~0.35; 所述第二组份中,PEG-60失水山梨醇硬脂酸酯和柔润剂的用量比为3%~6% : 1; 所述第三组份中,水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物的用量比为1: 0.8%~2% ; 所述第四组份中,乙酰基六肽-8、乙酰基三肽-30瓜氨酸和五肽的用量比为1:0.5~ 1.5:0.5~1.5,其工艺过程和产品品质能得到最佳平衡点。 [0008] found, by mass, of the first component, a second component, the third component and the fourth component with a ratio of 18 to 22: 19 to 23: 10 to 13: 1; the in said first component, water, EDTA disodium humectant with an equivalent ratio of 1: 0.1 to 0.2%: 0.25 to 0.35; the second set of compositions, PEG-60 sorbitan monostearate and emollients with a ratio of 3% to 6%: 1; the third component, the water and acrylic acid (acrylate) s / C10-30 alkanol acrylate polymer crosslinked with a ratio of 1: 0.8% to 2%; the fourth component, the acetyl hexapeptide -8, -30 tripeptide acetyl citrulline and pentapeptide with a ratio of 1: 0.5 to 1.5: 0.5 to 1.5, which process and product quality to get the best balance.

[0009] 进一步优选为:所述保湿剂包括3wt%~5wt%的三乙醇胺、2wt%~3wt%的透明质酸、55wt%~60wt%的甘油和32wt%~40wt%的双丙甘醇。 [0009] more preferably: said humectant comprises 3wt% ~ 5wt% of triethanolamine, 2wt% ~ 3wt% of hyaluronic acid, 55wt% ~ 60wt% of glycerol and 32wt% ~ 40wt% in dipropylene glycol.

[0010]采用上述技术方案,三乙醇胺、透明质酸、甘油和双丙甘醇之间联合作用,从肌肤的多层上进行锁水补水,且其清透,适用于体温相对较高的孕妇使用。 [0010] With the above technical solution, between the combined action triethanolamine, hyaluronic acid, glycerol and dipropylene glycol, the water replenishment for the lock from the skin layers, and it perfectly clear, relatively high temperature suitable for pregnant women use.

[0011 ] 进一步优选为:所述柔润剂包括Iwt %~2wt %的硬脂酸、2wt %~4wt %的甘油硬脂酸酯、2wt%~4wt%的聚二甲基硅氧烷、50wt%~60wt%的碳酸二辛酯、20wt%~25wt% 的辛酸/癸酸甘油三酯、2wt %~4wt %的海棠果籽油、5wt %~IOwt %的异壬酸异壬酯和8wt%~15wt%的鲸錯醇乙基己酸酯。 [0011] more preferably: said emollient comprises Iwt% ~ 2wt% of stearic acid, 2wt% ~ 4wt% glycerol stearate, 2wt% ~ 4wt% of polydimethylsiloxane, 50wt% ~ 60wt% of dioctyl carbonate, 20wt% ~ 25wt% caprylic / capric triglyceride, 2wt% ~ 4wt% of Malus oil, 5wt% ~ IOwt% of isononyl isononanoate and 8wt% ~ 15wt% of cetyl alcohol fault ethylhexanoate.

[0012] 采用上述技术方案,硬脂酸、甘油硬脂酸酯、聚二甲基硅氧烷、碳酸二辛酯、辛酸/ 癸酸甘油三酯、海棠果籽油、异壬酸异壬酯和鲸蜡醇乙基己酸酯联合作用,降粘及屈服点, 改善乳液体系的流动性和表面张力,易分散和易制备,得到分散均匀的乳状且该乳状稳定; 这些柔润剂联合作用后,涂抹时展开性好且易促进本申请的孕纹按摩乳吸收,使得皮肤光滑、柔润、富有弹性,肤感清透。 [0012] With the above technical solution, stearic acid, glyceryl stearate, dimethicone, dicaprylyl carbonate, caprylic / capric triglyceride, crabapple oil, isononyl isononanoate and cetyl ethylhexanoate combined effect of viscosity reduction and yield point, improving fluidity and surface tension of the emulsion system, easy to disperse and easy, to give a uniform dispersion and emulsion stability of the emulsion; the combined action of these emollients expand good when applied and easy to promote the application of this pattern massage milk pregnant absorbed, making the skin smooth and soft, flexible skin feeling perfectly clear.

[0013] 进一步优选为:所述第四组份还包括防腐剂和香精;按质量计,所述乙酰基六肽- 8、防腐剂和香精的用量比为1:0.2~0.5:0.1~0.2。 [0013] more preferably: The fourth component further comprises a preservative and fragrances; by mass, the hexapeptide acetyl - 8, preservatives and flavor with an equivalent ratio of 1: 0.2 to 0.5: 0.1 to 0.2 .

[0014] 采用上述技术方案,增加产品的使用寿命和调节产品的香味,提高产品的适用性。 [0014] With the above technical solution, increase the service life of the product and adjusting the fragrance of the product, to improve the suitability of the product. [0015] 进一步优选为:所述透明质酸包括Mr为(1~2) X IO6的HA和Mr为(1~8) X IO4的HA。 [0015] more preferably: Mr of the hyaluronic acid comprises (1 ~ 2) X IO6 HA and Mr of (1 ~ 8) HA X IO4 of.

[0016] 采用上述技术方案,小分子透明质酸进入肌肤对内层补水,而大分子透明质酸位于肌肤外内对皮肤表面进行锁水和吸水,提高皮肤含水量。 [0016] With the above aspect, a small molecule of hyaluronic acid into the skin moisturizing inner layer, the outer skin located in the hyaluronic acid molecules for the water-absorbing and water lock surface of the skin, enhancing skin moisture content.

[0017] 本发明的第二目的是提供所述孕纹按摩乳的制备方法。 [0017] The second object of the present invention is to provide a massage pattern pregnant milk preparation.

[0018] 本发明的上述技术目的是通过以下技术方案得以实现的: 一种所述的孕纹按摩乳的制备方法,包括如下步骤: 步骤1:将第一组份的各原料按配方量混合,搅拌加热至70~75°C,得到分散均匀的第一组份; 步骤2:将第二组份的各原料按配方量混合,搅拌加热至70~75°C,得到分散均匀的第二组份; 步骤3:将第三组份的各原料按配方量混合,搅拌,得到分散均匀的第三组份; 步骤4:将第四组份的各原料按配方量混合,搅拌,得到分散均匀的第四组份; 步骤5:保温状态下,于步骤1得到的第一组份中加入经步骤2处理得到的第二组份,均质,分散均匀;之后于保温状态下,于其中加入经步骤3处理得到的第三组份,均质,分散均匀;之后将料体冷却至42~45°C,再于其中加入经步骤4处理得到的第四组份,均质,分散均匀;之后冷却至25~30°C,即得。 [0018] The technical object of the present invention is achieved by the following technical solution: A method for preparing the pregnant pattern massage milk, comprising the following steps: Step 1: The first component formulation amount of each raw material mixed stirred and heated to 70 ~ 75 ° C, to obtain a uniform dispersion of the first component; step 2: the second component of the raw materials according to the formula amount of the mixed, stirred and heated to 70 ~ 75 ° C, to obtain a uniform dispersion of second component; step 3: the third component of the formulation according to the amount of the raw materials were mixed and stirred to obtain a uniform dispersion of the third component; step 4: the fourth component formulation amount of each raw material by mixing, with stirring, to obtain a dispersion even fourth component; step 5: the insulating state, added to the first component 1 obtained in step a second component obtained by the second processing step, a homogeneous, uniform dispersion; then incubated state, in which step 3 was added to give third component treated, homogeneous, uniform dispersion; after the material was cooled to 42 ~ 45 ° C, then was added to the fourth component obtained by the process of step 4, a homogeneous, uniform dispersion ; after cooling to 25 ~ 30 ° C, that is, too.

[0019]采用上述技术方案,过程中易分散且保持各原料活性,得到的产品分散性好且易展开。 [0019] With the above technical solution, easily dispersed and held during the respective active material, the product obtained is good dispersibility and easy deployment.

[0020]研究发现,按质量计,所述第一组份、第二组份、第三组份和第四组份的用量比为18~22:19~23:10~13:1; 所述第一组份包括水、EDTA二钠和保湿剂;第一组份中,水、EDTA二钠和保湿剂的用量比为1:0.1%~0.2%:0.25~0.35;所述保湿剂包括3wt %~5wt %的三乙醇胺、2wt %~ 3wt%的透明质酸、55wt%~60wt%的甘油和32wt%~40wt%的双丙甘醇;所述透明质酸包括Mr为(1 ~2) X IO6的HA和Mr为(1 ~8) X IO4的HA; 所述第二组份包括PEG-60失水山梨醇硬脂酸酯和柔润剂;所述第二组份中,PEG-60失水山梨醇硬脂酸酯和柔润剂的用量比为3%~6% : 1;所述柔润剂包括Iwt %~2wt%的硬脂酸、2wt %~4wt %的甘油硬脂酸酯、2wt %~4wt %的聚二甲基硅氧烷、50wt %~60wt %的碳酸二辛酯、20wt%~25wt%的辛酸/癸酸甘油三酯、2wt%~4wt%的海棠果籽油、5wt%~ IOwt %的异壬酸异壬酯和8wt %~15wt %的鲸錯醇乙基己酸酯; 第三组份包括水和丙烯酸(酯)类/C10-30烷 [0020] found, by mass, of the first component, a second component, the third component and the fourth component with a ratio of 18 to 22:19 to 23: 10 to 13: 1; the said first component comprising water, EDTA disodium, and humectants; a first component, the water, EDTA disodium humectant with an equivalent ratio of 1: 0.1 to 0.2%: 0.25 to 0.35; the humectant comprises 3wt% ~ 5wt% of triethanolamine, 2wt% ~ 3wt% of hyaluronic acid, 55wt% ~ 60wt% of glycerol and 32wt% ~ 40wt% in dipropylene glycol; Mr of the hyaluronic acid comprises (1 ~ 2 ) X IO6 HA and Mr of (1 ~ 8) HA X IO4; and the second component comprises PEG-60 sorbitan monostearate, and emollients; the second set of compositions, PEG- 60 sorbitan monostearate and emollients with a ratio of 3% to 6%: 1; the emollient comprises Iwt% ~ 2wt% of stearic acid, 2wt% ~ 4wt% of glyceryl stearate , 2wt% ~ 4wt% of polydimethylsiloxane, 50wt% ~ 60wt% of dioctyl carbonate, 20wt% ~ 25wt% caprylic / capric triglyceride, 2wt% ~ 4wt% oil of Malus , 5wt% ~ IOwt% of isononyl isononanoate and 8wt% ~ 15wt% of cetyl alcohol fault ethylhexanoate; a third component comprising water and acrylic acid (acrylate) s / C10-30 alkyl 丙烯酸酯交联聚合物,且所述第三组份中,水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物的用量比为1:0.8%~2%; 所述第四组份包括乙酰基六肽-8、乙酰基三肽-30瓜氨酸、五肽、防腐剂和香精,且所述第四组份中,乙酰基六肽-8、乙酰基三肽-30瓜氨酸、五肽、防腐剂和香精的用量比为1:0.5 ~1.5:0.5~1.5:0.2~0.5:0.1~0.2,其工艺过程和产品品质能得到最佳平衡点。 Crosslinked acrylate polymer, and the third component, the water and acrylic acid (acrylate) s / C10-30 alkanol acrylate polymer crosslinked with a ratio of 1: 0.8% to 2%; the first four-component include acetyl hexapeptide -8, -30 tripeptide acetyl citrulline, pentapeptides, preservatives and fragrances, and the fourth component, the acetyl hexapeptide-8, acetyl tripeptide - 30 citrulline, pentapeptides, preservatives and flavor with an equivalent ratio of 1: 0.5 to 1.5: 0.5 to 1.5: 0.2 to 0.5: 0.1 to 0.2, which process and product quality to obtain the best balance.

[0021 ]进一步优选为:所述海棠果籽油由如下方法制备得到: 取海棠果籽,加入乙醇水溶液,于5~30°C下保温超声0.5~2hr来浸提,浸提2~3次,合并浸提液,过滤并于5~30°C下保温浓缩得到醇提取物;于浓缩后的醇提取物中加入水,萃取后于5~30°C下挥干溶剂,即得。 [0021] more preferably: said Malus oil was prepared by the following method: taking Malus seeds, aqueous ethanol was added, incubated ultrasound at 5 ~ 30 ° C 0.5 ~ 2hr to leaching, extraction 3 times 2 the combined extract was filtered and the lower insulation 5 ~ 30 ° C and concentrated to give an alcohol extract; water was added to the concentrated alcohol extract, the lower and extracted after 5 ~ 30 ° C the solvent evaporated to dryness, to obtain.

[0022]采用上述技术方案,低温操作能保持海棠果籽的生物活性,同时通过上述方法制备得到的海棠果籽油收率高、润肤效果更好;采用挥干溶剂的海棠果籽油,无刺激,适用于孕妇。 [0022] With the above technical solution, low temperature operation can retain the biological activity of Malus seed, seed yield while crabapple obtained by preparing the above-described method, better emollient; solvent evaporated to dryness using Begonia fruit oil, no stimulation, suitable for pregnant women.

[0023]进一步优选为:所述海棠果籽原料经干燥和粉碎预处理,所述干燥为-20~(TC下冷冻干燥,粉碎为5~30 °C下保温粉碎;所述乙醇水溶液由75wt %~90wt %的乙醇和IOwt % ~25wt%的水构成,且按质量计所述海棠果籽的干重和每次浸提所用的乙醇水溶液的用量比为1:2~5,所述浓缩后的醇提取物和水的质量用量比为1:2~5。 [0023] more preferably: said Malus seed pretreated material dried and pulverized, the drying is -20 ~ (TC freeze-dried, crushed to the insulation 5 ~ 30 ° C pulverizing; the ethanol solution of 75wt % ~ 90wt% of ethanol and IOwt% ~ 25wt% of the aqueous composition, and by dry weight of the mass of seeds and each Malus aqueous ethanol extract prepared with a ratio of 1: 2 ~ 5, the concentrate after the mass of the alcohol extract and water with a ratio of 1: 2 ~ 5.

[0024] 采用上述技术方案,先用冷冻干燥对原料进行处理,使得原料瞬间失水而原来还基本保持原形态,其易粉碎且能与提取溶剂能快速作用来加速原料内的有效成分的溶出。 [0024] With the above technical solution, before the raw material is treated with freeze-dried, so that the original raw material and also substantially instantaneous loss to maintain the original shape, which is friable and can be fast acting with an extraction solvent able to accelerate dissolution of the active ingredient in the feed .

[0025] 综上所述,本发明具有以下有益效果: 1、 本申请采用的原料均无刺激或低刺激,且其混合后未产生刺激性产物,其温和无刺激,适用于孕妇和产妇使用; 2、 本申请的孕纹按摩乳去妊娠纹速度更快且效果更好,且其适用于孕期中、后期的孕妇和产妇; 3、 使用本申请的孕纹按摩乳后,肤感更清透,且提高涂抹展开性; 4、 使用本申请的孕纹按摩乳后皮肤更紧实,能改善皮肤松弛的情况,使皮肤更有光泽和富有弹性。 [0025] In summary, the present invention has the following advantages: 1, raw materials used in the present application low stimulation or no stimulation, and which is not irritating product after mixing, which moderate without stimulation, and the use of suitable pregnant women ; 2, pregnant pattern of this application to stretch marks massage milk faster and better, and it applies to pregnancy, the late pregnant women and mothers; 3, the use of this application pattern after pregnancy massage milk, skin feeling clearer permeability, spreadability and improve the smear; 4, used in this application pregnant breast massage pattern firmer skin, sagging skin can improve the situation, the skin shiny and flexible.

具体实施方式 detailed description

[0026] 除非特殊注明,本申请所用的原料均符合国际化妆品原料标准,因此在本申请中单一成分未注明来源。 [0026] Unless otherwise specified, starting materials used herein are in accordance with international standards of raw materials of cosmetics, in the present application thus does not indicate the source of a single component. 本具体实施例仅仅是对本发明的解释,其并不是对本发明的限制,本领域技术人员在阅读完本说明书后可以根据需要对本实施例做出没有创造性贡献的修改, 但只要在本发明的权利要求范围内都受到专利法的保护。 Embodiment of this particular embodiment is only illustrative of the present invention, and are not restrictive of the invention, those skilled in the art upon reading this specification modifications may be made without inventive contribution of the present embodiment as desired, but the claims of the present invention as long as the They are protected within the requirements of the patent laws.

[0027] 实施例1-3:海棠果籽油,其由如下方法制备得到: 预处理:取海棠果籽原料,于-20~0 °C下冷冻干燥至恒重,于5~30 °C下保温粉碎至100 ~200目; 提取:取经预处理的海棠果籽,加入乙醇水溶液,于5~30°C下保温超声0.5~2hr来浸提,浸提2~3次,合并浸提液,过滤并于5~30°C下保温浓缩得到醇提取物;于浓缩后的醇提取物中加入水,萃取后于5~30°C下挥干溶剂,即得; 实施例1_3的原料彳目息如表1所不。 [0027] Example 1-3: Malus oil, which is prepared by the following method: Pretreatment: Take Malus raw seeds, freeze-dried to constant weight at -20 ~ 0 ° C, at 5 ~ 30 ° C incubated pulverized to 100-200 mesh; extract: Malus learn seed pretreatment, aqueous ethanol was added, heat extraction by ultrasonic 0.5 ~ 2hr, leaching 2 to 3 times at 5 ~ 30 ° C, combined extracts , filtered and the insulation 5 ~ 30 ° C and concentrated to give an alcohol extract; water was added to the concentrated alcohol extract, the lower and extracted after 5 ~ 30 ° C the solvent evaporated to dryness, to obtain; Example 1_3 embodiment starting material left foot entry information in table 1 is not. 表1实施例1-3的海棠果籽油中各原料信息 Each oil feed information Malus Table 1. Example 1-3

Figure CN105963156AD00071

[0028] 实施例4-6:孕纹按摩乳,其由如下方法制备得到: 步骤1:将第一组份的各原料按配方量混合,搅拌加热至70~75°C,得到分散均匀的第一组份; 步骤2:将第二组份的各原料按配方量混合,搅拌加热至70~75°C,得到分散均匀的第二组份; 步骤3:将第三组份的各原料按配方量混合,搅拌,得到分散均匀的第三组份; 步骤4:将第四组份的各原料按配方量混合,搅拌,得到分散均匀的第四组份; 步骤5:保温状态下,于步骤1得到的第一组份中加入经步骤2处理得到的第二组份,均质,分散均匀;之后于保温状态下,于其中加入经步骤3处理得到的第三组份,均质,分散均匀;之后将料体冷却至42~45°C,再于其中加入经步骤4处理得到的第四组份,均质,分散均勾;之后冷却至25~30°C,即得; 实施例4_6的原料彳目息如表2所不。 [0028] Examples 4-6: pregnant pattern massage milk, which is prepared by the following method: Step 1: The first component formulation amount of each raw material by mixing, stirring and heated to 70 ~ 75 ° C, to obtain a uniform dispersion a first component; step 2: the second component formulation amount of each raw material mixed, stirred and heated to 70 ~ 75 ° C, to obtain a uniform dispersion of the second component; step 3: the third component of the raw materials according to the formula amount of the mixed and stirred to obtain a uniform dispersion of the third component; step 4: the fourth component formulation amount of each raw material mixed and stirred to obtain a uniform dispersion of the fourth component; step 5: the insulating state, was added to the second processing step a first component obtained in step 1 was the second component, the homogeneous, uniform dispersion; after incubation at a state, in which the third component is added in step 3 by treating the resulting homogeneous , evenly dispersed; after the material was cooled to 42 ~ 45 ° C, then was added to the fourth component obtained by the fourth processing step, a homogeneous dispersion were hook; after cooling to 25 ~ 30 ° C, to obtain; Example 4_6 starting material left foot destination information in table 2 is not. 表2实施例4-6的孕纹按摩乳中各原料信息 Table 2 Examples 4-6 pregnancy massage pattern of each raw material milk information

Figure CN105963156AD00081

[0029] 实施例7:孕纹按摩乳,与实施例5的不同之处在于,其海棠果籽油由法国绿科提供。 [0029] Example 7: Massage pregnant milk lines, with the exception that in Example 5, crabapple oil provided by the French Green Section.

[0030] 实施例8:孕纹按摩乳,与实施例5的不同之处在于,第一组份的保湿剂中,甘油用双丙甘醇替代。 [0030] Example 8: Massage pregnant milk lines, described in Example 5 except that the first set of parts of a humectant, the glycerine was replaced with dipropylene glycol.

[0031] 实施例9:孕纹按摩乳,与实施例5的不同之处在于,第一组份的保湿剂中,双丙甘醇用甘油替代。 [0031] Example 9: progesterone massage milk lines, described in Example 5 except that the first set of parts of a humectant, dipropylene glycol was replaced with glycerol.

[0032] 实施例10:孕纹按摩乳,与实施例5的不同之处在于,第一组份的保湿剂中,未添加三乙醇胺、Mr为(1~2) X IO6的HA和Mr为(1~8) X IO4的HA。 [0032] Example 10: Massage pregnant milk lines, described in Example 5 except that the first set of parts of a humectant, triethanolamine is not added, the Mr (1 ~ 2) X IO6 Mr of HA and (1 ~ 8) HA X IO4 of.

[0033] 实施例11:孕纹按摩乳,与实施例5的不同之处在于,第二组份的柔润剂中,未添加硬脂酸、甘油硬脂酸酯和聚二甲基硅氧烷。 [0033] Example 11: Massage pregnant milk lines, described in Example 5 except that the second component of emollients, no addition of stearic acid, glyceryl stearate, and dimethicone .

[0034] 实施例12:孕纹按摩乳,与实施例5的不同之处在于,第二组份的柔润剂中,未添加异壬酸异壬酯和鲸蜡醇乙基己酸酯。 [0034] Example 12: pregnancy massage milk lines, described in Example 5 except that the second component of emollients, no added isononyl isononanoate and cetyl ethylhexanoate.

[0035] 实施例13:孕纹按摩乳,与实施例5的不同之处在于,第二组份的柔润剂中,未添加辛酸/癸酸甘油三酯和海棠果籽油。 [0035] Example 13: Massage pregnant milk lines, described in Example 5 except that the second component of the emollient not added caprylic / capric triglyceride and Malus oil.

[0036]实施例14:孕纹按摩乳,与实施例5的不同之处在于,所有原料于室温(25°C)下直接搅拌混合,搅拌2hr,即得。 [0036] Example 14: Massage pregnant milk lines, the embodiment is different from Embodiment 5 is that all raw material is directly mixed with stirring at room temperature (25 ° C), stirred for 2 hr, to obtain.

[0037] 实施例15:按摩用修复妊娠纹精油,参照CN105534746A的实施例1制备,取50g甜杏仁油、8g小麦胚芽油、Ig香茅醛、Ig安基苯甲酸甲酯、1.5g丝素肽、0.5g透明质酸、2g赖氨酸、 2g椰子胶原蛋白、9g橘子精油、2g乳香精油、2g橙花精油、2g熏衣草精油、13g柑橘精油、5g乳香精油和Ig酪梨油,于室温(25°C)下直接搅拌混合,分散均匀,即得。 [0037] Example 15: repairing stretch marks massage oils, with reference to Preparation Example 1 CN105534746A, whichever 50g sweet almond oil, 8g of wheat germ oil, an Ig citronellal, an Ig Kay benzoate, 1.5 g fibroin peptides, 0.5g hyaluronic acid, 2g lysine, 2g coconut collagen protein, 9g orange essential oil, 2g frankincense, 2g orange blossom oil, 2g lavender essential oil, 13g citrus oils, 5g frankincense and Ig avocado oil, at room temperature (25 ° C) directly to the mixture under stirring, distributed evenly, ie.

[0038]实施例16:使用评价试验对象:以实施例4-14为试验样品,以实施例15为对照样。 [0038] Example 16: Evaluation using subjects: Example 4-14 as a test sample in Example 15 is still on.

[0039]试验内容A:随机选120名孕期为3-6个月且有轻微妊娠纹(呈粉红色)的孕妇,随机分成12组,每组10个人,每组使用一个试验对象;使用频率均为3次/天;分别于使用1周和1 个月后按表3对去妊娠纹效果进行评价,同时按表4和表5对涂抹体验进行评价; 试验内容B:随机选120名孕期为6-10个月且有明显妊娠纹(呈紫红色或黑色)的孕妇, 随机分成12组,每组10个人,每组使用一个试验对象;使用频率均为3次/天;分别于使用1周和1个月后按表3对去妊娠纹效果进行评价; 试验内容C:随机选120名生产1个月内且有明显妊娠纹(呈黑色)的产妇,随机分成12 组,每组10个人,每组使用一个试验对象;使用频率均为3次/天;分别于使用1周和1个月后按表3对去妊娠纹效果进行评价; 试验结果:妊娠纹去除效果如表6、8和9所示,涂抹体验评价如表7所示。 [0039] Content Test A: 120 randomly selected from 3-6 months of pregnancy and slightly stretch marks (pink) pregnant women were randomly divided into 12 groups of 10 individuals each, each using a test subject; frequency were 3 times / day; respectively, using 1 week and 1 month after stretch marks according to table 3 to evaluate the effects, while table 4 and table 5 were evaluated applicator experience; content test B: 120 randomly selected pregnancy 6-10 months and significantly stretch marks (purple or black) pregnant women were randomly divided into 12 groups of 10 individuals each, each using a test subject; frequency was 3 times / day; respectively use 1 week and 1 month after table 3 according to evaluate the effect of stretch marks; content test C: 120 randomly selected women within 1 month and produced a significant stretch marks (black) were randomly divided into 12 groups, each group 10 individuals, each using a test subject; frequency was 3 times / day; were used according to table 3 to evaluate the effect of stretch marks 1 week and 1 month; test results: table 6 stretch marks removal 8 and 9, the smear evaluation experience as shown in table 7.

[0040]表6、8和9显示:相比对照样,实施例4-14的孕纹按摩乳的去妊娠纹速度更快且效果更好,特别是在使用实施例4-6的按摩乳一个月后能妊娠纹变淡且范围缩小50%以上;实施例4-14的孕纹按摩乳的去妊娠纹适用于孕期中、后期的孕妇和产妇。 [0040] TABLE 6, 8 and 9 show: compared to control sample, lines 4-14 pregnancy stretch marks massage milk velocity to the embodiment faster and better, in particular in Example 4-6 Massage Milk stretch marks can fade after a month and more than 50% narrowing; Example 4-14 gestational pattern of massage milk suitable to stretch marks during pregnancy, and late pregnant women.

[0041 ]表7显示:相比对照样,涂抹实施例4-14后的肤感更清透,且涂抹展开性一般或易展开,特别是在使用实施例4-6的按摩乳后易展开且肤感清透。 [0041] Table 7 shows: in comparison to the still, the applicator according to Embodiment 4-14 afterfeel more perfectly clear and easy to apply deployment of ships or expand, especially when using the embodiment of Example 4-6 easily massage expand milk and skin feel refreshed.

[0042]同时,研究发现,使用实施例4-14后皮肤更紧实,能改善皮肤松弛的情况,使皮肤更有光泽和富有弹性;且使用实施例4-6后的皮肤改善效果最佳。 [0042] At the same time, found that the use of embodiments 4-14 firmer skin, improves flabby skin, the skin shiny and flexible; and most skin improvement effect after use of embodiment Examples 4-6 . 表3妊娠纹去除效果评价标准 Table 3 Evaluation standard stretch marks removal

Figure CN105963156AD00091

Figure CN105963156AD00101

Figure CN105963156AD00111

Claims (10)

  1. 1. 一种孕纹按摩乳,其特征在于,包括第一组份、第二组份、第三组份和第四组份;其中, 所述第一组份包括水、EDTA二钠和保湿剂; 所述第二组份包括PEG-60失水山梨醇硬脂酸酯和柔润剂; 第三组份包括水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物; 所述第四组份包括乙酰基六肽-8、乙酰基三肽-30瓜氨酸和五肽。 A pregnancy massage milk lines, characterized by comprising a first component, a second component, the third component and the fourth component; wherein the first component comprises water, EDTA disodium and moisturizing agent; the second component comprises PEG-60 sorbitan monostearate, and emollients; a third component comprising water and acrylic acid (acrylate) s / C10-30 alkanol acrylate cross-linked polymer; the said fourth component include acetyl hexapeptide -8, -30 tripeptide acetyl citrulline and pentapeptides.
  2. 2. 根据权利要求1所述的孕纹按摩乳,其特征在于,按质量计,所述第一组份、第二组份、第三组份和第四组份的用量比为18~22:19~23:10~13:1; 所述第一组份中,水、EDTA二钠和保湿剂的用量比为1:0.1%~0.2%:0.25~0.35; 所述第二组份中,PEG-60失水山梨醇硬脂酸酯和柔润剂的用量比为3%~6%: 1; 所述第三组份中,水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物的用量比为1: 0.8%~2%; 所述第四组份中,乙酰基六肽-8、乙酰基三肽-30瓜氨酸和五肽的用量比为1:0.5~1.5: 0·5~1·5〇 The massage pattern pregnant milk according to claim 1, characterized by mass of the first component, a second component, the third component and the fourth component with a ratio of 18 to 22 : 19 to 23: 10 to 13: 1; the first component, the water, EDTA disodium humectant with an equivalent ratio of 1: 0.1 to 0.2%: 0.25 to 0.35; the second set of compositions , PEG-60 sorbitan monostearate, and emollients with a ratio of 3% to 6%: 1; the third component, the water and acrylic acid (acrylate) s / C10-30 alkanol acrylate crosslinked polymer with an equivalent ratio of 1: 0.8% to 2%; the fourth component, the acetyl hexapeptide -8, -30 tripeptide acetyl citrulline and pentapeptide with a ratio of 1: 0.5 to 1.5: 5 to 1 · 0 · 5〇
  3. 3. 根据权利要求2所述的孕纹按摩乳,其特征在于,所述保湿剂包括3wt%~5wt%的三乙醇胺、2wt%~3wt%的透明质酸、55wt%~60wt%的甘油和32wt%~40wt%的双丙甘醇。 The pregnant breast massage pattern according to claim 2, wherein said humectant comprises 3wt% ~ 5wt% of triethanolamine, 2wt% ~ 3wt% of hyaluronic acid, 55wt% ~ 60wt% of glycerol and of 32wt% ~ 40wt% dipropylene glycol.
  4. 4. 根据权利要求2所述的孕纹按摩乳,其特征在于,所述柔润剂包括lwt%~2wt%的硬脂酸、2wt%~4wt%的甘油硬脂酸酯、2wt%~4wt%的聚二甲基硅氧烷、50wt%~60wt%的碳酸二辛酯、 20wt%~25wt%的辛酸/癸酸甘油三酯、2wt%~4wt%的海棠果籽油、5wt%~10wt%的异壬酸异壬酯和8wt%~15wt%的鲸錯醇乙基己酸酯。 The pregnant breast massage pattern according to claim 2, characterized in that said emollient comprises lwt% ~ 2wt% of stearic acid, 2wt% ~ 4wt% glycerol stearate, 2wt% ~ 4wt% polydimethyl siloxane, 50wt% ~ 60wt% of dioctyl carbonate, 20wt% ~ 25wt% caprylic / capric triglyceride, 2wt% ~ 4wt% of Malus oil, 5wt% ~ 10wt% the isononyl isononanoate and 8wt% ~ 15wt% of cetyl alcohol fault ethylhexanoate.
  5. 5. 根据权利要求2所述的孕纹按摩乳,其特征在于,所述第四组份还包括防腐剂和香精;按质量计,所述乙酰基六肽-8、防腐剂和香精的用量比为1:0.2~0.5:0.1~0.2。 According to claim pregnancy massage milk lines 2, wherein the fourth component further comprises a preservative and fragrances; amount by mass, the acetyl hexapeptide-8, preservatives and flavors ratio of 1: 0.2 to 0.5: 0.1 to 0.2.
  6. 6. 根据权利要求3所述的孕纹按摩乳,其特征在于,所述透明质酸包括Mr为(1~2) X106 的HA和Mr为(1~8) X 104的HA。 According to claim pregnancy massage milk lines 3, wherein the HA comprises a Mr of hyaluronic acid (1 ~ 2) X106 HA and Mr of (1 ~ 8) X 104 in.
  7. 7. -种如权利要求1-6任一项所述的孕纹按摩乳的制备方法,其特征在于,包括如下步骤: 步骤1:将第一组份的各原料按配方量混合,搅拌加热至70~75°C,得到分散均匀的第一组份; 步骤2:将第二组份的各原料按配方量混合,搅拌加热至70~75°C,得到分散均匀的第二组份; 步骤3:将第三组份的各原料按配方量混合,搅拌,得到分散均匀的第三组份; 步骤4:将第四组份的各原料按配方量混合,搅拌,得到分散均匀的第四组份; 步骤5:保温状态下,于步骤1得到的第一组份中加入经步骤2处理得到的第二组份,均质,分散均匀;之后于保温状态下,于其中加入经步骤3处理得到的第三组份,均质,分散均匀;之后将料体冷却至42~45°C,再于其中加入经步骤4处理得到的第四组份,均质,分散均匀;之后冷却至25~30°C,即得。 7. - Preparation pregnant pattern of one of the claims 1-6 kinds of massage milk as claimed in claim, characterized in that it comprises the following steps: Step 1: The first component formulation amount of each raw material by mixing, heated with stirring to 70 ~ 75 ° C, to obtain a uniform dispersion of the first component; step 2: the second component formulation amount of each raw material mixed, stirred and heated to 70 ~ 75 ° C, to obtain a uniform dispersion of the second component; step 3: the third component of the formulation according to the amount of the raw materials were mixed and stirred to obtain a uniform dispersion of the third component; step 4: the fourth component of the raw materials were mixed in formulation amounts, and stirred to obtain a uniform dispersion of four parts; step 5: the insulating state, in a first step by the addition of component 1 obtained in step 2 to obtain a second processing component, the homogeneous, uniform dispersion; after incubation at a state, in which the step was added the third component of the third process obtained, a homogeneous, uniform dispersion; after the material was cooled to 42 ~ 45 ° C, then was added to the fourth component obtained by the process of step 4, a homogeneous, uniform dispersion; after cooling to 25 ~ 30 ° C, that is, too.
  8. 8. 根据权利要求7所述的孕纹按摩乳的制备方法,其特征在于, 按质量计,所述第一组份、第二组份、第三组份和第四组份的用量比为18~22:19~23:10 ~13:1; 所述第一组份包括水、EDTA二钠和保湿剂;第一组份中,水、EDTA二钠和保湿剂的用量比为1:0.1%~0.2%: 0.25~0.35;所述保湿剂包括3wt%~5wt%的三乙醇胺、2wt%~3wt%的透明质酸、55wt%~60wt%的甘油和32wt%~40wt%的双丙甘醇;所述透明质酸包括Mr为(1~2)X10 6的HA和Mr为(1~8) X 104的HA; 所述第二组份包括PEG-60失水山梨醇硬脂酸酯和柔润剂;所述第二组份中,PEG-60失水山梨醇硬脂酸酯和柔润剂的用量比为3%~6%: 1;所述柔润剂包括lwt%~2wt%的硬脂酸、 2wt%~4wt%的甘油硬脂酸酯、2wt%~4wt%的聚二甲基硅氧烷、50wt%~60wt%的碳酸二辛酯、 20wt%~25wt%的辛酸/癸酸甘油三酯、2wt%~4wt%的海棠果籽油、5wt%~10wt%的异壬酸异壬酯和8wt%~15wt%的鲸錯醇乙基己酸酯; 第三 Pregnant pattern according to claim 7, said method for preparing milk massage, characterized by mass of the first component, a second component, the third component and the fourth component with an equivalent ratio of 18 ~ 22: 19 ~ 23: 10 ~ 13: 1; the first component comprises water, EDTA disodium, and humectants; a first component, the water, EDTA disodium humectant with an equivalent ratio of 1: 0.1% to 0.2%: 0.25 to 0.35; the humectant comprises 3wt% ~ 5wt% of triethanolamine, 2wt% ~ 3wt% of hyaluronic acid, 55wt% ~ 60wt% of glycerol and 32wt% ~ 40wt% dipropylene glycol; Mr of the hyaluronic acid comprises (1 ~ 2) HA and Mr X10 6 is (1 ~ 8) HA X 104; and the second component comprises PEG-60 sorbitan stearate esters and emollients; the second set of compositions, PEG-60 sorbitan monostearate, and emollients with a ratio of 3% to 6%: 1; the emollient comprises lwt% ~ 2wt% of stearic acid, 2wt% ~ 4wt% glycerol stearate, 2wt% ~ 4wt% of polydimethylsiloxane, 50wt% ~ 60wt% of dioctyl carbonate, 20wt% ~ 25wt% of caprylic / capric triglyceride, 2wt% ~ 4wt% of Malus oil, 5wt% ~ 10wt% of isononyl isononanoate and 8wt% ~ 15wt% of cetyl alcohol fault ethylhexanoate; third 份包括水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物,且所述第三组份中,水和丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物的用量比为1:0.8%~2%; 所述第四组份包括乙酰基六肽-8、乙酰基三肽-30瓜氨酸、五肽、防腐剂和香精,且所述第四组份中,乙酰基六肽-8、乙酰基三肽-30瓜氨酸、五肽、防腐剂和香精的用量比为1:0.5~ 1·5:0·5~1·5:0·2~0·5:0·1~0·2〇 Including parts of water and acrylic acid (acrylate) s / C10-30 alkanol acrylate cross-linked polymer, and the third component, the water and acrylic acid (acrylate) s / C10-30 alkanol acrylate cross-linked polymer with a ratio of 1: 0.8% to 2%; the fourth component include acetyl hexapeptide -8, -30 tripeptide acetyl citrulline, pentapeptides, preservatives and fragrances, and the fourth group parts, acetyl hexapeptide -8, -30 tripeptide acetyl citrulline, pentapeptides, preservatives and flavor with an equivalent ratio of 1: 0.5 to 1.5: 5 to 1 · 0 · 5: 0 · 2 ~ 0 · 5: 0 · 1 to 0 · 2〇
  9. 9. 根据权利要求8所述的孕纹按摩乳的制备方法,其特征在于,所述海棠果籽油由如下方法制备得到: 取海棠果籽,加入乙醇水溶液,于5~30°C下保温超声0.5~2hr来浸提,浸提2~3次,合并浸提液,过滤并于5~30°C下保温浓缩得到醇提取物;于浓缩后的醇提取物中加入水,萃取后于5~30°C下挥干溶剂,即得。 9. The gestational pattern according to claim 8 massage milk production method, wherein said crabapple oil prepared by the following method: taking Malus seeds, an aqueous solution of ethanol was added, incubated at 5 ~ 30 ° C 0.5 ~ 2hr leach to ultrasound, extraction 2-3 times, extracts were combined, filtered and the alcoholic extract at 5 ~ 30 ° C and concentrated to give insulation; water was added to the concentrated alcohol extract is extracted after at 5 ~ 30 ° C the solvent evaporated to dryness, to obtain.
  10. 10. 根据权利要求9所述的孕纹按摩乳的制备方法,其特征在于,所述海棠果籽原料经干燥和粉碎预处理,所述干燥为-20~0 °C下冷冻干燥,粉碎为5~30°C下保温粉碎;所述乙醇水溶液由75wt%~90wt%的乙醇和10wt%~25wt%的水构成,且按质量计所述海棠果籽的干重和每次浸提所用的乙醇水溶液的用量比为1:2~5,所述浓缩后的醇提取物和水的质量用量比为1:2~5 〇 10. The pattern of the progesterone production method of claim 9 massage milk, wherein said seed material Malus pre-dried and pulverized, the drying is freeze drying at -20 ~ 0 ° C, was pulverized under incubated 5 ~ 30 ° C pulverizing; the aqueous ethanol solution composed of 75wt% ~ 90wt% ethanol and 10wt% ~ 25wt% of water, and by the mass of the dry weight of seed Malus each extraction and used aqueous ethanol ratio of 1: 2 to 5, and the mass of the alcohol extract water after the concentrate with a ratio of 1: 2 to 5 billion
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JP2016056205A (en) * 2016-01-14 2016-04-21 花王株式会社 Mfap-4 production promoter

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102341A1 (en) * 2001-06-14 2002-12-27 Alfred Denner Cosmetic treatment method for stretch marks
US20070280898A1 (en) * 2006-06-06 2007-12-06 P & H Enterprises Of Marco Inc. Dermatological compositions
WO2008080443A2 (en) * 2007-01-04 2008-07-10 Labo Cosprophar Ag Cosmetic composition for the treatment and/or prevention of skin stretch marks
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