CN105960265A - 利用经化学修饰的寡核苷酸处理伤口愈合的方法 - Google Patents

利用经化学修饰的寡核苷酸处理伤口愈合的方法 Download PDF

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Publication number
CN105960265A
CN105960265A CN201480074839.8A CN201480074839A CN105960265A CN 105960265 A CN105960265 A CN 105960265A CN 201480074839 A CN201480074839 A CN 201480074839A CN 105960265 A CN105960265 A CN 105960265A
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nucleic acid
acid molecule
administered
nucleotides
hours
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Chinese (zh)
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格拉尔德·考文贝赫
帕梅拉·A·帕夫科
林恩·利伯蒂娜
卡伦·G·布洛克
詹姆斯·卡迪亚
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Phio Pharmaceuticals Corp
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RXi Pharmaceuticals Corp
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CN201480074839.8A 2013-12-04 2014-12-04 利用经化学修饰的寡核苷酸处理伤口愈合的方法 Pending CN105960265A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361911993P 2013-12-04 2013-12-04
US201361911991P 2013-12-04 2013-12-04
US61/911,993 2013-12-04
US61/911,991 2013-12-04
US201462049299P 2014-09-11 2014-09-11
US62/049,299 2014-09-11
PCT/US2014/068654 WO2015085113A1 (en) 2013-12-04 2014-12-04 Methods for treatment of wound healing utilizing chemically modified oligonucleotides

Publications (1)

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CN105960265A true CN105960265A (zh) 2016-09-21

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Country Status (7)

Country Link
US (1) US20160304875A1 (https=)
EP (1) EP3077050B1 (https=)
JP (2) JP6883987B2 (https=)
KR (1) KR20160110370A (https=)
CN (1) CN105960265A (https=)
CA (1) CA2932753A1 (https=)
WO (1) WO2015085113A1 (https=)

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CN111773392A (zh) * 2020-05-25 2020-10-16 河南省生物工程技术研究中心 一种人血白蛋白/寡核苷酸纳米颗粒及其制备方法和用途
CN113092461A (zh) * 2021-04-09 2021-07-09 四川大学华西医院 一种通过选择性识别叶酸受体的循环肿瘤细胞的均相二维可视化/荧光分析方法及应用
CN113842496A (zh) * 2021-09-28 2021-12-28 五峰赤诚生物科技股份有限公司 一种创面液体敷料及其制备方法

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WO2010059226A2 (en) 2008-11-19 2010-05-27 Rxi Pharmaceuticals Corporation Inhibition of map4k4 through rnai
WO2010078536A1 (en) 2009-01-05 2010-07-08 Rxi Pharmaceuticals Corporation Inhibition of pcsk9 through rnai
US9745574B2 (en) 2009-02-04 2017-08-29 Rxi Pharmaceuticals Corporation RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
EP3494790A1 (en) 2010-03-02 2019-06-12 Phio Pharmaceuticals Corp. Effective sensitizing dose of a gelled immunomodulating topical composition
RU2615143C2 (ru) 2010-03-24 2017-04-04 Адвирна Самодоставляющие PHKi соединения уменьшенного размера
CN103200945B (zh) 2010-03-24 2016-07-06 雷克西制药公司 眼部症候中的rna干扰
EP3560503B1 (en) 2010-03-24 2021-11-17 Phio Pharmaceuticals Corp. Rna interference in dermal and fibrotic indications
CN106061488B (zh) 2013-12-02 2021-04-09 菲奥医药公司 癌症的免疫治疗
WO2015168108A2 (en) 2014-04-28 2015-11-05 Rxi Pharmaceuticals Corporation Methods for treating cancer using nucleic targeting mdm2 or mycn
US10900039B2 (en) 2014-09-05 2021-01-26 Phio Pharmaceuticals Corp. Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1
EP3862005A1 (en) 2015-07-06 2021-08-11 Phio Pharmaceuticals Corp. Nucleic acid molecules targeting superoxide dismutase 1 (sod1)
US10808247B2 (en) 2015-07-06 2020-10-20 Phio Pharmaceuticals Corp. Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
US20210052631A1 (en) * 2015-09-25 2021-02-25 Ionis Pharmaceuticals, Inc. Conjugated antisense compounds and their use
WO2017070151A1 (en) 2015-10-19 2017-04-27 Rxi Pharmaceuticals Corporation Reduced size self-delivering nucleic acid compounds targeting long non-coding rna
US12544344B2 (en) 2017-04-19 2026-02-10 Phio Pharmaceuticals Corp. Topical delivery of nucleic acid compounds
CN111557913B (zh) * 2020-07-07 2022-05-31 中国科学院空天信息创新研究院 靶向癫痫细胞的纳米光敏复合物及调控检测系统

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