CN105944026A - 一种治疗乳腺增生的苗药 - Google Patents
一种治疗乳腺增生的苗药 Download PDFInfo
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Abstract
一种治疗乳腺增生的苗药,该苗药所用药材质量配比为:拔契36~50,桂枝6~10,橘核20~25,柴胡8~15,牡蛎20~30,三棱6~9,文术6~9,赤芍10~15,山慈菇5~10,黄芪25~30,猪鬃草30~35,威灵仙20~25,路路通12~15,当归15~20,五香血芚30~35,皂角刺15。制法是先取山慈菇,去除杂质研末待用;再取余下15味药材,除去杂质,混合,粉碎成粗末,煎煮3次,药液混合、过滤,加温、浓缩成膏状,烘干干燥,研末,与山慈菇混匀,消毒,即得。本苗药具有疏肝理气,活血化瘀功效,疗效明显,治愈率达88%,服用安全,加工方便,适用于治疗乳腺增生及乳腺炎的患者。
Description
技术领域
本发明与医用配制品有关,具体而言,涉及治疗乳房疾病的药物,尤其涉及治疗乳腺增生的苗药。
背景技术
乳腺增生是指乳腺上皮和纤维组织增生,乳腺组织导管和乳小叶在结构上的退行性病变及进行性结缔组织生长。是女性最常见的乳房疾病,可发生于青春期以后的任何年龄的妇女。临床上主要表现为:月经来潮前,乳房胀满疼痛,月经来潮乳房胀痛缓解乃至消失,待下次月经来潮前又出现周期性的变化。传统中药有乳核饮、清肝解郁汤、散癖安乳方等。
近年来,出现一批利用中草药材治疗乳腺小叶增生的药物的中国专利申请件,例如:200410001738.6号《一种治疗乳腺小叶增生的膏药及其制备方法》、200510052266.1号《治疗乳腺小叶增生的药物及其制备工艺》、200610146922.9号《专治乳腺小叶增生的化核膏》、200810231128.3号《治疗乳腺小叶增生的药物》、201010571766.7号《治疗妇女乳腺小叶增生的外用中药制剂及其制备方法》、201110173439.0号《治疗乳腺小叶增生的中药》、201210566042.2号《治疗乳腺小叶增生病中药配方》和201310161952.7号《一种治疗乳腺小叶增生的中药》等,均公开了一些利用中药材配制的药物。但人们仍然在开发更新、更好的药物。
苗族有悠久的民族文化,苗医苗药就是苗族文化的一部分,其中有许多疗效显著的验方,其中201310号《一种治疗乳腺小叶增生的苗药》。但人们仍然继续期待疗效更好的药物。
发明内容
本发明旨在提供一种治疗乳腺增生的苗药,以增加治疗乳房疾患的药物品种,使之能够为妇女的健康服务。
本发明是基于苗族对植物药的研究,优选出来的配方和制备工艺。
本发明的治疗乳腺增生的苗药所用药材的质量配比为:
拔契36~50,桂枝6~10,橘核20~25,柴胡8~15,牡蛎20~30,三棱6~9,文术6~9,赤芍10~15,山慈菇5~10,黄芪25~30,猪鬃草30~35,威灵仙20~25,路路通12~15,当归15~20,五香血芚30~35,皂角刺15。
该苗药的优选配方为:
拔契40,桂枝8,橘核22,柴胡12,牡蛎25,三棱7,文术8,赤芍12,山慈菇8,黄芪28,猪鬃草32,威灵仙22,路路通14,当归18, 32,皂角刺15。
上述药材中:
菝葜,为百合科植物菝葜(Smilax china)的根茎,性平,味甘苦,能祛风湿,利小便,清肿毒(见浙江新医学院编《中药大辞典》1996页);桂枝为樟科植物肉桂(Cinnamomum cassia)的嫩枝,味辛甘,性温,能发汗解肌,温经通脉(见《中药大辞典》1771页);橘核,为芸香科植物福橘(Citrum tangerina)或朱橘(Citrum erythrosa)的种子,味苦,性平,能理气、止痛(见《中药大词典》2640页);柴胡为伞形科植物北柴胡(Bupleurum chinense)的根,味苦,性凉,有和解表里、疏肝升阳功效(见《中药材大辞典》1832页);牡蛎,为牡蛎科动物近江牡蛎(Ostrea rivularis) 等的贝壳,味咸涩、性凉,能敛阴、潜阳,止汗,涩精,化痰,软坚(见《中药大辞典》1124页);三棱为黑三棱科植物黑三棱(Sparganium stoloniferum)的块根,味苦辛,性平,能破血、行气、消积、止痛(见《中药材大辞典》56页);文术,即蓬莪术,为姜科植物莪术(Curcuma lzedoaria)的根茎,味辛苦、性温,有行气、破血、消积、止痛功效(见《中药大辞典》2450页);赤芍药为毛茛科植物芍药(Paeonia lactiflora) 的根,味酸苦,性凉,能行气、止痛、凉血、消肿(见《中药大辞典》1093页);山慈姑,为兰科植物杜鹃兰(Cremastra variabilis)的干燥假鳞茎, 味微甘辛,性温,有消肿散结功效(见《中药材大辞典》201页);黄芪即黄耆,为豆科植物黄耆(Astragalus membranaceus)的干燥根,味甘,性微温,能益卫固表、利水消肿、补中益气(见《中药大辞典》2036页);猪鬃草为铁线蕨科植物铁线蕨(Adiantum capillus-veneris)的全草,味苦,性凉,能清热、祛风。利尿、消肿(见《中药大辞典》2202页);威灵仙为毛茛科植物威灵仙(Clematis chinensis)的根,味辛咸,性温,有毒,能去风湿,通经络,消痰涎,散癖积(见《中药大辞典》1632页);路路通为金缕梅科植物枫香(Liquidambar formoana) 的果实,味苦,性平,能祛风、通络,利水,除湿(见《中药大辞典》2485页);当归,为伞形科植物当归(Angelica sinensis)的根,味甘辛,性温,有补血和血、调经止痛、润燥滑肠的作用(见《中药大辞典》876页);五香血芚为木兰植物长梗五味子(Kadsura longipedunculata)的茎藤,味甘,性温,有活血祛风,消肿镇痛功效(见《中药材大辞典》395页);皂角刺为豆科植物皂荚(Gleditsia sinensis)的棘刺,味辛,性温,有搜风、拔毒、消肿、排脓功效(《中药材大辞典》1145页)。
上述药材应符合《中国药典》1995年版一部中各药材项下的规定。
本发明的治疗乳腺增生的苗药的制备方法是:按照配方比例取山慈菇10份,去除杂质研末,过60目,待用;取拔契36份、桂枝6份、橘核20份、柴胡8份、牡蛎20份、三棱6份、文术6份、赤芍10份;黄芪25份、猪鬃草30份、威灵仙20份、路路通12份、当归10份、五香血芚30份、皂角刺15份,分别除去杂质,混合,粉碎成粗末,入锅内煎煮40分钟,取出药液,如此煎煮三次,混合药液,用两层纱布过滤,加温,浓缩成膏状,烘干干燥,研末过60目,与山慈菇混合拌匀,经紫外线消毒,装入胶囊,即得。
本苗药功能主治:理气活血,消肿散结。主治乳腺增生。
本苗药可以常规中药制剂方法制备成任何一种常用口服剂型。
本发明的治疗乳腺增生的苗药使用方法是口服,一次3至5粒,一天3次,温开水送服。禁忌:孕妇,无乳腺增生者忌服。
本发明的治疗乳腺增生的苗药已在临床进行试验应用,共收治患者17例,治愈15例,2例无效。治愈率88%。典型病例有:
病例一:张某,女38岁,双侧乳房结块3年多,逐渐扩散长大,月经来前胀痛、肿块变硬,经净则软,月经不调,属于典型的乳腺增生。曾服用多种中药,无效,后服用本发明的胶囊1月,肿块消失,月经正常。
病例二:申某,女,39岁,双侧乳房结块胀痛,毕节市医院诊断为乳腺增生,服中药半年无效,后服本发明的胶囊一年后,见面告知病愈,双侧乳房包块散尽。
病例三:方某,42岁,双侧乳腺增生多年,因服用很多药物,均无效,已失去治疗信心,后经人介绍先吃本发明的苗药试用,20天后,双侧包块已消去大半,继服1月,痊愈,半年后随访病未复发。
本发明的治疗乳腺增生的苗药具有疏肝理气,活血化瘀功效,疗效明显,服用安全,加工方便,适用于治疗乳腺增生及乳腺炎的患者。
具体实施方式
实施例 按照下列步骤制备治疗乳腺增生的苗药:
取山慈菇10g,去除杂质研末,过60目,待用,取拔契36g、桂枝6g、橘核20g、柴胡8g、牡蛎20g、三棱6g、文术6g、赤芍10g;黄芪25g、猪鬃草30g、威灵仙20g、路路通12g、当归10g、五香血芚30g、皂刺15g,分别除去杂质,混合,粉碎成粗末,入锅内煎煮40min,取出药液,如此煎煮3次,混合药液,用两层纱布过滤,加温,浓缩成膏状,烘干干燥,研末过60目,与山慈菇混合拌匀,经紫外线消毒,装入胶囊,每粒1g,即得到治疗乳腺增生的胶囊剂。
Claims (3)
1.一种治疗乳腺增生的苗药,其特征在于该苗药所用药材的质量配比为:
拔契36~50,桂枝6~10,橘核20~25,柴胡8~15,牡蛎20~30,三棱6~9,文术6~9,赤芍10~15,山慈菇5~10,黄芪25~30,猪鬃草30~35,威灵仙20~25,路路通12~15,当归15~20,五香血芚30~35,皂角刺15。
2.如权利要求1所述治疗乳腺增生的苗药,其特征在于该苗药所用药材的质量配比为:
拔契40,桂枝8,橘核22,柴胡12,牡蛎25,三棱7,文术8,赤芍12,山慈菇8,黄芪28,猪鬃草32,威灵仙22,路路通14,当归18, 32,皂角刺15。
3.制备权利要求1所述的治疗乳腺增生的苗药的方法,其特征是按照配方比例取山慈菇10份,去除杂质研末,过60目,待用;取拔契36份、桂枝6份、橘核20份、柴胡8份、牡蛎20份、三棱6份、文术6份、赤芍10份;黄芪25份、猪鬃草30份、威灵仙20份、路路通12份、当归10份、五香血芚30份、皂角刺15份,分别除去杂质,混合,粉碎成粗末,入锅内煎煮40分钟,取出药液,如此煎煮三次,混合药液,用两层纱布过滤,加温,浓缩成膏状,烘干干燥,研末过60目,与山慈菇混合拌匀,经紫外线消毒,装入胶囊,即得。
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