CN105943714A - Pharmaceutical composition for treating carbuncle - Google Patents

Pharmaceutical composition for treating carbuncle Download PDF

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Publication number
CN105943714A
CN105943714A CN201610471342.0A CN201610471342A CN105943714A CN 105943714 A CN105943714 A CN 105943714A CN 201610471342 A CN201610471342 A CN 201610471342A CN 105943714 A CN105943714 A CN 105943714A
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CN
China
Prior art keywords
skin
pharmaceutical composition
pericarpium citri
citri reticulatae
anas domestica
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Pending
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CN201610471342.0A
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Chinese (zh)
Inventor
符如忠
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Individual
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Individual
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Priority to CN201610471342.0A priority Critical patent/CN105943714A/en
Publication of CN105943714A publication Critical patent/CN105943714A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli

Abstract

The invention discloses a pharmaceutical composition for treating carbuncle, which is prepared by a preparation method comprising the following steps of: (1) raw material preparation: preparing three raw materials including the bark of Indian stringbush root, rock sugar and green duck eggs according to a weight ratio of (4-6) to (22-28) to (70-80) for later use; (2) raw material treatment: adding 10 times of water to the Indian stringbush root, decocting and filtering to obtain decoction; and (3) adding broken green duck effects with shell removed and rock sugar, boiling and cooling. The pharmaceutical composition is used for overcoming the defects of the existing medicines for treating carbuncle, and has a good treatment effect when used for treating carbuncle.

Description

A kind of pharmaceutical composition treating skin infection
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of pharmaceutical composition treating skin infection.
Background technology
Skin infection, refers to carry on skin virose scar to swell rotten suppuration, also known as Peptic Ulcers.Peptic Ulcers Canker is by Valsa (Valsa), Botryosphaeria (Botryos-phaeria), the red shell of clump Belong to funguses such as (Nectria) and yellow pseudomonas bacillus belongs to (Xanthomonas), pseudomonas.Poison Skin ulcer is to suppurate, and makes blood vessel and muscular tissue and skin be corroded, becomes the thinnest very destructible.Skin infection heat Skin infection and eczema of lower limb.Pyretic toxicity skin ulcer i.e. heat-toxin type skin sore.Heat-toxin type skin sore symptom: pustule type pimple is main, Pustule is assembled, time have a small amount of bonum et laudabile pus liquid excessive, around often have blush, conscious pain, pustule disappears After, skin surface can leave over the little cicatrix of pitting, shape such as Pericarpium Citri Reticulatae, and thoracic dorsal is often involved, is hard and dry Or constipated, a few days is not all right, yellowish or reddish urine, has pantatrophia, and immunity is poor, red tongue, tongue Yellow dry;Eczema of lower limb, has noxious dampness in being because health, removes with regard to president's skin infection not in time, also with self Immunocompetence have much relations.
Therapeutic Method, around cleaning skin infection, wash clean of sterilizing, then discharge skin with Chinese patent medicine targetedly Malicious water below skin tissue, conditioning endocrine increases immunity and just can fully recover.Can also take The medicine enhanced metabolism, or antibiotic, promote immunity of organisms.Take a good rest at ordinary times, Strike a proper balance between work and rest, strengthen taking exercise, improve the immunity of self, it is also possible to reduce the incidence probability of skin infection. Conventional Chinese medicine, it is possible to use Flos Lonicerae, Flos Chrysanthemi Indici, Herba Taraxaci, Chinese medicine decoction, the every day five such as pale reddish brown Secondary averagely with Flos Lonicerae and Radix Isatidis decoction or oral cefixime glue assist 0.1g/ time, Beijing together Core hall compound recipe cattleSheet 3 pieces/times, dab for four times totally night with medicinal alcohol Morning Afternoon Evening, also have certain Effect, but also there is also to middle deficiency.
Therefore, research will have important meaning for the Chinese medicine of skin infection.
Summary of the invention
The technical problem to be solved in the present invention is the deficiency overcoming existing treatment skin infection medicine, it is provided that a kind of The treatment preferable pharmaceutical composition of skin infection effect.
In pharmaceutical composition of the present invention, consumption and the preparation method of each component are that inventor is through a large amount of real Trampling what summary drew, the pharmaceutical composition for the treatment of skin infection of the present invention, by following preparation method Obtain:
1) raw material prepares: prepare the skin of Radix Wikstroemae, ice according to the weight ratio of 4-6:22-28:70-80 Sugar, three kinds of raw materials of Pericarpium Citri Reticulatae Viride Ovum Anas domestica, standby;
2) Feedstock treating: add 10 times of water in the skin of Radix Wikstroemae, decoct, be filtrated to get decoction liquor;
3) to step 2) in the decoction liquor that obtains, add the Pericarpium Citri Reticulatae Viride Ovum Anas domestica after broken shelling and crystal sugar, Boil, cooling, both.
Step 1 of the present invention) described in the skin of Radix Wikstroemae, crystal sugar, Pericarpium Citri Reticulatae Viride Ovum Anas domestica, preferably according to 5:25:75 Weight ratio.
Step 1) the Pericarpium Citri Reticulatae Viride Ovum Anas domestica that used is the most effective, and Rhizoma Euonymus Ovum Anas domestica does not has effect.
Step 2) described in decoction, with reference to prior art.
In pharmaceutical composition side of the present invention, with Radix Wikstroemae as monarch drug, treating the poisonous disease with poisonous drugs, take its heat-clearing and toxic substances removing, The effect of dispersing swelling and dissipating binds, with crystal sugar as ministerial drug, replenishing YIN and removing heat, eliminating damp, detoxifying, Pericarpium Citri Reticulatae Viride Ovum Anas domestica is adjuvant drug, Attack with poison, first effect a permanent cure, after take stopgap measures, take after can treating the poisonous disease with poisonous drugs can promote that soft tissue regeneration flesh is put on flesh.
Radix Wikstroemae (Wikstroemia indica (Linn.) C.A.Mey), Latin literary fame: Wikstroemia indica(Linn.)C.A.Mey.Have another name called wikstroemia indica, cotton skin, Clausena lansium (Lour.) Skeels Son, cotton root, mountain bean or pea, little Flos Wikstroemiae Nutantis, Cortex paulowniae, brother's spring scenery, passeris montani saturati infantile paralysis etc..Widely distributed Each province on the south China the Changjiang river, is mainly born in grass slope, hills or shrubbery.Belong to Isolated From Thymelaeaceae Species, winter daphne Section, Flos Wikstroemiae Dolichanthae belong to shrub.Root bark (wikstroemin) Han wickstoemin, and containing wickstromol (wikstoeniol), arctigenin-4'-gentiobioside (arctigenin), martairesinol (matairesinol) With fir pinoresinol (pinamoresinol).Root separates 4 materials with anticancer activity, wherein One of for daphnoretin (daphnoretn);Another proposition Radix Wikstroemae polysaccharide body-1 (WIP-1) from root, Mean molecule quantity 5000-6000, paper chromatography and thin layer qualification result, WIP-1 be by glucose, Ah Drawing uncle's sugar, galacturonic acid, galactose and xylose composition, its mol ratio is 28:6:2:1, between monosaccharide Connected mode be connected as main with α-(1-4), next to that α (1-3) connects.Wickstromol is to rabbit Central nervous system has inhibitory action, shock the mice spasm caused is had spasmolysis, LD50 For 65mg/kg.Radix Wikstroemae begins to be loaded in " south of the Five Ridges gather medicinal herbs record ", has another name called nine letter dishes, is loaded in " the SHENGCAO property of medicine For wanting ".Root, stem, leaf and fruit medicine, poisonous, there is heat-clearing and toxic substances removing, dissipating blood stasis of subsiding a swelling, control scrofula Scrofula, the effect swollen and ache.The water cooking liquid of its blade can parasite killing, peel of stem fiber can papermaking, make cotton, seed Because of containing oils and fats can soapmaking, whole strain can make poison fish medicine.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, pain relieving. Control scrofula, carbuncle, rheumatalgia, pertussis, traumatic injury.Taboo: this product has severe toxicity, with appropriate to the occasion Careful, the person of having a delicate constitution be not taken by pregnant women.
Crystal sugar, the traditional Chinese medical science thinks that crystal sugar has lung moistening, cough-relieving, clearing away phlegm and the effect reduced internal heat.Also it is bubble Pharmacy wine, the stewed adjuvant boiling tonic.Crystal sugar has invigorating the spleen and replenishing QI, stomach function regulating lung moistening, relieving cough and resolving phlegm, dispels Tired quench one's thirst, heat clearing away the turbid descending, YIN nourishing and the production of body fluid promoting, the function such as hidroschesis removing toxic substances, can be used for treating deficiency of QI in middle-JIAO, Cough due to lung-heat, sputum with blood, deficiency of YIN chronic cough, dryness of the mouth and throat, laryngopharynx swelling and pain, infantile night sweat, wind-fire The diseases such as toothache.Effect: invigorating the spleen and replenishing QI, stomach function regulating lung moistening, relieving cough and resolving phlegm.Nature and flavor: sweet in the mouth, property be flat, Nontoxic.Gui Jing: enter lung, spleen channel.Effect: YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough.Cure mainly: xeropulmonary cough, Dry cough without phlegm, sputum with blood.Crystal sugar is put down, and has effect of relieving cough and resolving phlegm, is widely used in food and doctor The high-grade tonic of medicine industry production and health product.Old man can also alleviate dry mouth and tougue containing changing crystal sugar.Medicine Reason effect: internal water and sugar can be supplemented, have supplementary body fluid, supply energy, supplement blood glucose, Heart tonifying diuresis, removing toxic substances etc. act on.Indication: its 5% solution is isotonic solution, for various acute poisonings, To promote poisonous substance excretion;10-50% is high solution, for hypoglycemia, malnutrition, or for the heart The treatment of force failure, cerebral edema, pulmonary edema etc..
Pharmaceutical composition of the present invention, cures mainly various skin infection, and can solve pressurized position with patient and draw Play the pressure ulcer in portion, decubital ulcer, furuncle or the moon such as local skin necrosis, ulcer, back, bone portion, heel Skin ulcer, also can cure simultaneously: the diseases such as parotitis, not broken skin infection, skin ulcer intestinal, cirrhotic ascites.
Detailed description of the invention
With specific embodiment, the invention will be further described below, but the invention is not limited in these Embodiment.
Embodiment 1
A kind of pharmaceutical composition treating skin infection, is prepared by the following preparation method:
1) raw material prepares: prepare the skin of Radix Wikstroemae, crystal sugar, Pericarpium Citri Reticulatae Viride according to the weight ratio of 4:28:70 Three kinds of raw materials of Ovum Anas domestica, standby;
2) Feedstock treating: add 10 times of water in the skin of Radix Wikstroemae, decoct, be filtrated to get decoction liquor;
3) to step 2) in the decoction liquor that obtains, add the Pericarpium Citri Reticulatae Viride Ovum Anas domestica after broken shelling and crystal sugar, Boil, cooling, both.
Embodiment 2
A kind of pharmaceutical composition treating skin infection, is prepared by the following preparation method:
1) raw material prepares: prepare the skin of Radix Wikstroemae, crystal sugar, Pericarpium Citri Reticulatae Viride according to the weight ratio of 6:22:80 Three kinds of raw materials of Ovum Anas domestica, standby;
2) Feedstock treating: add 10 times of water in the skin of Radix Wikstroemae, decoct, be filtrated to get decoction liquor;
3) to step 2) in the decoction liquor that obtains, add the Pericarpium Citri Reticulatae Viride Ovum Anas domestica after broken shelling and crystal sugar, Boil, cooling, both.
Embodiment 3
A kind of pharmaceutical composition treating skin infection, is prepared by the following preparation method:
1) raw material prepares: prepare the skin of Radix Wikstroemae, crystal sugar, Pericarpium Citri Reticulatae Viride according to the weight ratio of 5:25:75 Three kinds of raw materials of Ovum Anas domestica, standby;
2) Feedstock treating: add 10 times of water in the skin of Radix Wikstroemae, decoct, be filtrated to get decoction liquor;
3) to step 2) in the decoction liquor that obtains, add the Pericarpium Citri Reticulatae Viride Ovum Anas domestica after broken shelling and crystal sugar, Boil, cooling, both.
Use the pharmaceutical composition of the present invention, to the cure rate of skin infection more than 99%, to parotitis, The diseases such as not broken skin infection, skin ulcer intestinal, cirrhotic ascites, effective percentage is more than 98%.
As a comparison, present invention applicant's skin folk prescription to Radix Wikstroemae the most respectively, and the skin of Radix Wikstroemae, Crystal sugar, the combination of Rhizoma Euonymus Ovum Anas domestica, done contrast test, and experimental result shows the effect of prescription of the present invention Considerably beyond above contrast experiment's effect.
Model case 1: accord with certain, man, 52 years old, in April, 1992 was thrown from eminence, has got injured by a fall the right side Brain cranial injury and waist 2 vertebra folding, becoming left and right hip after central nervous system injury has pressure ulcer, cotton-padded mattress Skin ulcer, on August 28th, the 2014 the most totally 22 older pressure ulcers that nobody can cure, decubital ulcer, takes this Bright pharmaceutical composition, eats egg and eats soup, and once a day, serve on 7 days, recovery from illness.
Model case 2: Zhang, female, 55 years old, decubital ulcer 3 years, take pharmaceutical composition of the present invention, Eat egg to eat soup, once a day, serve on 3 days, recovery from illness.
Model case 3: Zhao, female, 35 years old, suffer from the erosion of vulva, take pharmaceutical composition of the present invention, Eat egg to eat soup, once a day, serve on 4 days, recovery from illness.

Claims (2)

1. the pharmaceutical composition treating skin infection, it is characterised in that obtained by following preparation method Arrive:
1) raw material prepares: prepare the skin of Radix Wikstroemae, ice according to the weight ratio of 4-6:22-28:70-80 Sugar, three kinds of raw materials of Pericarpium Citri Reticulatae Viride Ovum Anas domestica, standby;
2) Feedstock treating: add 10 times of water in the skin of Radix Wikstroemae, decoct, be filtrated to get decoction liquor;
3) to step 2) in the decoction liquor that obtains, add the Pericarpium Citri Reticulatae Viride Ovum Anas domestica after broken shelling and crystal sugar, Boil, cooling, both.
A kind of pharmaceutical composition treating skin infection the most according to claim 1, it is characterised in that: Step 1) described in the skin of Radix Wikstroemae, crystal sugar, Pericarpium Citri Reticulatae Viride Ovum Anas domestica, according to the weight ratio of 5:25:75.
CN201610471342.0A 2016-06-24 2016-06-24 Pharmaceutical composition for treating carbuncle Pending CN105943714A (en)

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Application Number Priority Date Filing Date Title
CN201610471342.0A CN105943714A (en) 2016-06-24 2016-06-24 Pharmaceutical composition for treating carbuncle

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Application Number Priority Date Filing Date Title
CN201610471342.0A CN105943714A (en) 2016-06-24 2016-06-24 Pharmaceutical composition for treating carbuncle

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263548A (en) * 2013-05-27 2013-08-28 布焕景 Embrocation for treating haemorrhoids and application thereof
CN103356812A (en) * 2012-04-01 2013-10-23 杨文龙 Indian stringbush root granule

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103356812A (en) * 2012-04-01 2013-10-23 杨文龙 Indian stringbush root granule
CN103263548A (en) * 2013-05-27 2013-08-28 布焕景 Embrocation for treating haemorrhoids and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
黄變才主编: "《常用中草药识别与应用》", 30 September 2003, 化学工业出版社 *

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Application publication date: 20160921

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