CN105920342A - 一种治疗气阴两虚型慢性肾小球肾炎的中药组合物 - Google Patents
一种治疗气阴两虚型慢性肾小球肾炎的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗气阴两虚型慢性肾小球肾炎的中药组合物,其特征是由下列重量配比的药材制成:沙参10‑15份、玄精石20‑25份、玉竹9‑12份、棒棒草6‑9份、黑阳参12‑15份、牛毛七12‑15份、浙地黄25‑30份、余甘子25‑30份、黄花鸢尾6‑9份、跳八丈15‑20份、二色补血草20‑25份、过山枫12‑15份、鸡卵草20‑25份、炙甘草6‑9份。本发明的中药组合物,用于治疗气阴两虚型慢性肾小球肾炎,有效率高,疗效可靠,愈后不再复发。
Description
技术领域
本发明涉及一种中药,特别是一种用于治疗气阴两虚型慢性肾小球肾炎的中药组合物。
背景技术
中医将慢性肾小球肾炎归属于“水肿”、“虚劳”、“腰痛”、“血尿”等范畴。引起其发病原因主要有以下几点:①、外邪侵袭,内伤脾肾,脾肾虚损。②、外界气候的寒冷、潮湿,可以引起身体沉重,腹大胫肿。在五行中湿属土,寒属水,外湿侵袭多能伤脾,寒水外受多致伤肾。另外,脾虚则易有湿邪为患,肾阳不足则可寒水泛滥而致病。③、慢性肾炎一般多属阴水,故其诱因与酒色、饮食、劳累有关。慢性肾小球肾炎临床表现呈多样性,蛋白尿、血尿、高血压、水肿为其基本临床表现,可有不同程度肾功能减退,病情时轻时重、迁延,渐进性发展为慢性肾衰竭。目前,治疗慢性肾小球肾炎的方法主要有:中医治疗、西医治疗等,中医治疗取得了很好的疗效。中医根据不同原因引起的慢性肾小球肾炎,结合临床实际进行辨证治疗,将本病分为:肺肾气虚型、脾肾阳虚型、肝肾阴亏型、气阴两虚型、脾肾衰败型等。
发明内容
本发明的目的旨在提供一种治疗气阴两虚型慢性肾小球肾炎的中药组合物,通过选择合适的药材及其配比,达到安全有效治愈气阴两虚型慢性肾小球肾炎的目的。
为达到上述目的,本发明采用以下技术方案:一种治疗气阴两虚型慢性肾小球肾炎的中药组合物,其特征是由下列重量配比的药材制成:
沙参10-15份、玄精石20-25份、玉竹9-12份、棒棒草6-9份、黑阳参12-15份、牛毛七12-15份、浙地黄25-30份、余甘子25-30份、黄花鸢尾6-9份、跳八丈15-20份、二色补血草20-25份、过山枫12-15份、鸡卵草20-25份、炙甘草6-9份。
配方中所涉及到的药材的来源及功能主治如下:
沙参【来源】药材基源:为桔梗科植物沙参、杏叶沙参、轮叶沙参、云南沙参、泡沙参及其同属数种植物的根。【性味】味甘;微苦;性微寒【归经】归肺;胃经【功能主治】养阴清热;润肺化痰;益胃生津。主阴虚久咳;痨嗽痰血;燥咳痰少;虚热喉痹;津伤口渴。
玄精石【来源】药材基源:为硫酸盐类石膏族矿物石膏的晶体。【性味】咸;寒【归经】肾;脾;胃经【功能主治】滋阴;降火;软坚;消痰。主阳盛阴虚;壮热烦渴;头风脑痛;目赤障翳;重舌;木舌;咽喉肿痛;头疮;水火烫伤。
玉竹【来源】药材基源:为百合科植物玉竹的根茎。【性味】甘;平【归经】肺;胃经【功能主治】滋阴润肺;养胃生津。主燥咳;劳嗽;热病阴液耗伤之咽干口渴;内热消渴;阴虚外感;头昏眩晕;筋脉挛痛。
棒棒草【来源】药材基源:为石竹科植物短小孩儿参的干燥块根。【性味】甘;苦;微温【功能主治】补肺;健脾;养阴生津。主肺虚咳嗽;脾虚食少;心悸自汗;疲惫乏力;口干。
黑阳参【来源】药材基源:为紫草科植物长蕊斑种草的根。【性味】苦;微甘;微寒【归经】肺;胃经【功能主治】养阴清热;利湿解毒;散瘀消肿。主虚瘤发热;小便淋涩;痈肿疮毒;走马牙疳;跌打损伤。
牛毛七【来源】药材基源:为曲尾藓科植物山毛藓的全草。【性味】甘;淡;平【归经】心;肺经【功能主治】养阴清热;安神定志;祛风除湿;止血镇痛。主骨蒸潮热;神经衰弱;风湿麻木;筋骨疼痛;癫狂;外伤出血。
浙地黄【来源】药材基源:为玄参科植物天目地黄的根状茎。【性味】味甘;苦;性寒【功能主治】清热凉血;养阴生津。主温热病高热烦躁;吐血衄血;口干;咽喉肿痛;中耳炎;烫伤。
余甘子【来源】药材基源:为大戟科植物余甘子的果实。【性味】味苦;甘;酸;性凉【归经】脾;胃经【功能主治】清热利咽;润肺化痰;生津止渴。主感冒发热;咳嗽;咽痛;白喉;烦热口渴;高血压。
黄花鸢尾【来源】药材基源:为鸢尾科植物黄花鸢尾的根茎。【性味】苦;凉【功能主治】清热利咽。主咽喉肿痛。
跳八丈【来源】萝藦科匙羹藤属植物华宁藤Gymnema foetidum
Tsiang,以根入药。四季可采,洗净切段,鲜用或晒干。【性味】辛、涩,微温。【功能主治】舒筋活血,安胎止痛。用于跌打损伤,风湿骨痛,腰痛,胎动不安,肾炎,闭经,痛经。
二色补血草【来源】药材基源:为白花丹科植物二色补血草的根或全草。【性味】甘;微苦;性微温【归经】脾;肝;膀胱经【功能主治】益气血;散瘀止血。主病后体弱;胃脘痛;消化不良;妇女月经不调,崩漏;带下;尿血;痔血。
过山枫【来源】药材基源:为卫矛科植物过山枫的根【性味】苦;辛;凉【归经】肝;胆;肾经【功能主治】清热解毒;祛风除湿。主风湿痹痛;痛风;肾炎;胆囊炎;白血病。
鸡卵草【来源】兰科鸡卵草Habenaria tentaculata
Reichb. f.,以块根入药。【功能主治】止痛,消炎,生肌,止血,行气,补肾。
炙甘草【来源】本品为甘草的炮制加工品。【性味】甘,平。【归经】归心、肺、脾、胃经 。【功能主治】补脾和胃,益气复脉。用于脾胃虚弱,倦怠乏力,心动悸,脉结代。
气阴两虚型慢性肾小球肾炎临床表现为面色无华或面色晦黯,少气乏力或易感冒,午后低热或手足心热,口干咽燥或长期咽痛,舌偏红,少苔,脉细或细数或细涩。配方中的各药物之间相互配合,协同作用,所制成的中药具有益气养阴、清热活血等功效,能有效治疗气阴两虚型慢性肾小球肾炎,多年来,通过对50例此类患者的跟踪调查统计,有效率达96%,治疗效果好。
下面结合临床实验数据来说明本发明的有益效果:
1、抽样方法
从我单位近五年来确诊为气阴两虚型慢性肾小球肾炎的患者中,随机选取100例病人,年龄30-60岁。随机分为对照组和治疗组,每组各50人。两组年龄等资料无显著性差异,具有可比性。
2、试验方法
2.1对照组患者使用百令胶囊 ,按说明书服用。
2.2治疗组口服本发明按照具体实施例1制得的中药颗粒,早、中、晚各一次。疗程8周。
3、疗效标准及治疗结果
完全缓解:水肿等症状与体征完全消失,尿蛋白检查持续阴性,或24小时尿蛋白定量持续小于0.2g,高倍镜下尿红细胞消失,尿沉渣计数正常,肾功能正常。基本缓解:水肿等症状与体征基本消失,尿蛋白检查持续减少50%以上,高倍镜下尿红细胞不超过3个,尿沉渣计数接近正常。肾功能正常或基本(与正常值相差不超过15%)。好转:水肿等症状与体征明显好转,尿蛋白持续减少一个(+),或24小时尿蛋白定量持续减少25%以上,高倍镜下尿红细胞不超过5个,肾功能正常或有改善。无效:临床表现与上述实验室检查均无明显改善或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
由此可见,采用本发明的组方制得的药物能够安全有效治疗气阴两虚型慢性肾小球肾炎。
具体实施方式
下面结合具体实施的例子对本发明做进一步详细的描述。
实施例1
称取沙参10克、玄精石20克、玉竹9克、棒棒草6克、黑阳参12克、牛毛七12克、浙地黄25克、余甘子25克、黄花鸢尾6克、跳八丈15克、二色补血草20克、过山枫12克、鸡卵草20克、炙甘草6克。将以上各种药材粉磨成末,然后用常规方法“全成分”提取制成速溶中药颗粒,按照每小袋10克进行分装,密闭,于阴凉、干燥处保存。
用于治疗气阴两虚型慢性肾小球肾炎。口服,每日分早、中、晚三次服用。
实施例2
称取沙参13克、玄精石22克、玉竹10克、棒棒草8克、黑阳参13克、牛毛七14克、浙地黄27克、余甘子28克、黄花鸢尾8克、跳八丈18克、二色补血草22克、过山枫14克、鸡卵草22克、炙甘草8克。将以上各种药材粉磨成末,然后用常规方法“全成分”提取制成速溶中药颗粒,按照每小袋10克进行分装,密闭,于阴凉、干燥处保存。
用于治疗气阴两虚型慢性肾小球肾炎。口服,每日分早、中、晚三次服用。
实施例3
称取沙参15克、玄精石25克、玉竹12克、棒棒草9克、黑阳参15克、牛毛七15克、浙地黄30克、余甘子30克、黄花鸢尾9克、跳八丈20克、二色补血草25克、过山枫15克、鸡卵草25克、炙甘草9克。将以上各种药材粉磨成末,然后用常规方法“全成分”提取制成速溶中药颗粒,按照每小袋10克进行分装,密闭,于阴凉、干燥处保存。
用于治疗气阴两虚型慢性肾小球肾炎。口服,每日分早、中、晚三次服用。
Claims (1)
1.一种治疗气阴两虚型慢性肾小球肾炎的中药组合物,其特征是由下列重量配比的药材制成:沙参10-15份、玄精石20-25份、玉竹9-12份、棒棒草6-9份、黑阳参12-15份、牛毛七12-15份、浙地黄25-30份、余甘子25-30份、黄花鸢尾6-9份、跳八丈15-20份、二色补血草20-25份、过山枫12-15份、鸡卵草20-25份、炙甘草6-9份。
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CN103127420A (zh) * | 2013-02-26 | 2013-06-05 | 山东省立医院 | 一种治疗慢性肾小球肾炎的中药组合物 |
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