CN105920270A - Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof - Google Patents

Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof Download PDF

Info

Publication number
CN105920270A
CN105920270A CN201610407136.3A CN201610407136A CN105920270A CN 105920270 A CN105920270 A CN 105920270A CN 201610407136 A CN201610407136 A CN 201610407136A CN 105920270 A CN105920270 A CN 105920270A
Authority
CN
China
Prior art keywords
parts
chinese medicine
herba
fructus
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610407136.3A
Other languages
Chinese (zh)
Inventor
谭英
夏冰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610407136.3A priority Critical patent/CN105920270A/en
Publication of CN105920270A publication Critical patent/CN105920270A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and a preparation method thereof, and belongs to the field of traditional Chinese medicines. Raw materials of effective ingredients of the traditional Chinese medicine injection are as follows: python gallbladder, herb of cornuted pugionium, fetid gymnema, mulberry fruit, fruit of fragrant melodinus, herb of drooping carpesium, shorttube lycoris, fruit of Indian nightshade, root of hemandialeaf stephania, root of common embelia, medicated leaven, root of Chinese indigo, Shouliang yam rhizome, rhizome of drug sweetflag, wormseed mustard and Hainan rambutan. The selected medicines of the traditional Chinese medicine injection are compatible properly, meet the theories of traditional Chinese medicine and pharmacy and modern medicine and pharmacology; the traditional Chinese medicine injection has the effects of releasing the liver and activating the blood circulation, decreasing swelling and relieving pain, and resolving toxin and dissipating binds, and has unique curative effects after being used for nursing the postoperative anesthetic adverse reactions; and the traditional Chinese medicine injection is low in cost, is safe and reliable without any toxic or side effects, provides safe guarantee for operation success, has miraculous effects, is practicable, and is worthy of wide popularization and application in clinic.

Description

A kind of Chinese medicine for nursing postoperative anesthetis untoward reaction and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine for nursing postoperative anesthetis untoward reaction And preparation method.
Background technology
When anesthesia is to perform a surgical operation or carry out diagnostic test operation time for eliminate pain, ensure patient safety, create good Good surgical condition and the various methods taked, mainly include general anesthesia, local anesthesia and combined anesthesia.Anesthesia original meaning refers to sense Feel or the forfeiture of consciousness, the most then refer to make patient not feel pain and uncomfortable shape when undergoing surgery or invasive operates State.It is generally believed that anesthesia is a kind of nervus centralis and the reversibility merit of peripheral nervous system produced by medicine or additive method Can suppress, the feature of this suppression mainly feels the forfeiture of the particularly pain sensation.Over the course for the treatment of, anaesthetic effect is bad and art The reasons such as middle operating difficulties, need to extend operating time, increase anesthetics dosage, thus cause anaesthetic in various degree secondary The generation of reaction, common are paraesthesia, dysphoria, muscular tremor, convulsions, respiration inhibition etc..
It is clinically used for nursing postoperative anesthetis untoward reaction at present many based on Western medicine, but treated symptom itself is bad Reaction, even can increase the weight of this untoward reaction when using western medicine.Therefore, a kind of Chinese medicine without any side effects is selected to note Penetrate agent to solve the misery of patient.
Summary of the invention
The invention provides a kind of Chinese medicine for nursing postoperative anesthetis untoward reaction and preparation method;This Selected by bright Chinese medicine, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has soothing liver-QI and invigorate blood circulation, subside a swelling Pain relieving, effect of detoxicating and resolving stagnation of pathogens, be used for nursing postoperative anesthetis untoward reaction and have unique curative effect, and cost is relatively low, and safety can Lean on, without any side effects, provide safety guarantee for successful surgery, special effect is practical, wide popularization and application on clinic.
For achieving the above object, technical scheme is implemented as follows:
A kind of Chinese medicine for nursing postoperative anesthetis untoward reaction, makes described Chinese medicine effective ingredient Raw material composition and parts by weight be:
Make described Chinese medicine effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Chinese medicine for nursing postoperative anesthetis untoward reaction, walks including following technique Rapid:
(1) Fel python, Herba Solani Surattensis, Radix Stephaniae hemandifoliae, Rhizoma Acori Calami and Herba Erysimi Cheiranthoidis are put into container, carry out pulverization process, grind into powder, obtain Cross the fine powder of 180 mesh, standby;
(2) Herba Pugionii Cornuti, Fructus Melodini Suaveolentis, Massa Medicata Fermentata, Radix indigoferae incarnatae, Rhizoma Dioscoreae Cirrhosae and Fructus nephelii topengii are cleaned, put into container, add 8~10 times amount Distilled water, after soaking 5~6 hours, boils 3~4 hours, extracts;Again add 6~8 times amount distilled water, boil 2~3 hours, Extract;Finally, add 4~6 times amount distilled water, heated and boiled 1~2 hours, extract;Merge three extracting solution, filter, obtain filter Liquid, standby;
(3) moccasin tree and Fructus Mori are cleaned, immerse 5 times amount 80% alcohol solution dipping 1~2 hours, heating extraction 3 Hour, reclaim ethanol, filter, obtain filtrate, standby;
(4) Herba Carpesii Cernui, Bulbus Lycoridis Radiatae and Radix embeliae laetae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby;
(5) fine powder obtained by above-mentioned steps (1)~(4), filtrate and juice are mixed, and add 10~12 times amount Distilled water, after stirring and dissolving is uniform, heated and boiled 0.5 hour, stand 1 hour, extract and filter, obtain liquid medicine, liquid medicine fill is sealed Deposit, obtain the described Chinese medicine for nursing postoperative anesthetis untoward reaction.
The property of medicine of Chinese medicine used by the present invention is as follows:
Fel python: sweet-bitter flavor, cold in nature;Enter liver, spleen two warp.Dampness, parasite killing, improving eyesight.Control gastral cavity abdomen worm pain, dysentery, epilepsy disease, hemorrhoid Skin ulcer, corneal nebula swells and ache." not Lu " carries: " main trusted subordinate reveals pain, and hideing skin ulcer in bottom, mesh swells and ache.”
Herba Pugionii Cornuti: acrid in the mouth, warm in nature;GUIXIN, lung, stomach warp.Circulation of qi promoting, pain relieving, help digestion, removing toxic substances.Main fullness and distention in the chest and hypochondrium, dyspepsia, Alimentary toxicosis." Inner Mongol Chinese herbal medicine " carries: " circulation of qi promoting, pain relieving help digestion, removing toxic substances.Control dyspepsia, fullness and distention in the chest and hypochondrium, alimentary toxicosis.”
Moccasin tree;Sweet in the mouth, pungent, slightly warm in nature.Expelling wind and removing dampness, menstruction regulating and pain relieving.Curing mainly rheumatic numbness, bones and muscles pain, traumatic injury damages Wound, epilepsy, menoxenia, dysmenorrhea, trick in menstrual period cold type of pain." China's book on Chinese herbal medicine " carries: " wind-expelling pain-stopping;Promoting blood flow to regulate menstruation.Main air arthralgia chiefly caused by damp pathogen Bitterly, traumatic injury, menoxenia, dysmenorrhea, furuncle furuncle and phyma.”
Fructus Mori: sweet in the mouth, acid, cold in nature;GUIXIN, liver, kidney channel.Enrich blood YIN nourishing, promote the production of body fluid and moisturize.For vertigo and tinnitus, cardiopalmus is lost Sleeping, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation." occupying diet spectrum with breath " carries: " liver nourishing kidney, congested liquid dispel the wind Wet, walk with vigorous strides to carry out, cease wind syndrome caused by deficiency, clear asthenic fire.”
Fructus Melodini Suaveolentis: bitter in the mouth, cool in nature.Promoting the circulation of QI to relieve pain, removing food stagnancy reduces phlegm.For dyspepsia, infantile malnutrition, orchitis, colicky, Stomachache, cough with copious phlegm." Guangdong Chinese medicine " carries: " circulation of qi promoting, pain relieving.Controlling peratodynia, chest and diaphragm is glutted, lymphoid tuberculosis.”
Herba Carpesii Cernui: bitter in the mouth, pungent, cold in nature.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For cold, fever, laryngopharynx swelling and pain, have a toothache, acute Enteritis, dysentery, urinary tract infection, tuberculous lymphadenitis;Furuncle toxic swelling, mastitis, parotitis, herpes zoster, venom are controlled in external. " Yunnan Chinese herbal medicine " carries: " control infantile pneumonia, urinary tract infection.Furuncle mashes deposited affected part with fresh leaf.”
Bulbus Lycoridis Radiatae: acrid in the mouth, sweet, warm in nature.Eliminate the phlegm emetic, detoxicating and resolving stagnation of pathogens.Curing mainly acute throat trouble, single bilateral tonsillitis, laryngopharynx swelling and pain, sputum is stopped up Plug, alimentary toxicosis, chest and abdomen hydrops, malignant boil toxic swelling, sucutaneous nodule scrofula, anal fistula, traumatic injury, rheumatic arthritis, stubborn dermatitis, burn and scald, Venom.
Herba Solani Surattensis: bitter in the mouth, cold in nature, under rushing down, antidote against snake bite.Cure mainly constipation, venom." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control tooth Toothache, is coated with it for end.Treat nasal sinusitis, dispel the wind, only headache, exorcising.”
Radix Stephaniae hemandifoliae: bitter in the mouth, cold in nature;GUIXIN, liver, large intestine channel.Heat-clearing and toxic substances removing, eliminating stasis to stop pain.Main flu, pharyngalgia, diarrhoea, dysentery Disease, cellulitis toxic swelling, stomachache, wind syndrome of head pain, rheumatic arthralgia, traumatic injury.
Radix embeliae laetae: sour in the mouth, puckery, cool in nature.Heat-clearing and toxic substances removing, dissipating blood stasis stops blooding.Control laryngopharynx swelling and pain, gingiva bleeding gingival hemorrhage, diarrhea due to hypofunction of the spleen, fall Beat stasis of blood pain, hemorrhoid." Luchuan book on Chinese herbal medicine " carries: " antiinflammatory, sterilization.Control stomatitis, laryngitis, gingivitis, furuncle ulcer etc..And Xie great Cha Poison of drug, wood eat poison, Fructus Crotonis poison.”
Massa Medicata Fermentata: sweet in the mouth, pungent, warm in nature, nontoxic;Return spleen, stomach warp.Invigorating the spleen and regulating the stomach, helps digestion in tune.Control retention of food and drink, feeling of stuffiness in chest abdomen Swollen, vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen heavily fortified point amasss." book on Chinese herbal medicine is stated " carries: " cure the wound summer-heat, and being affected by fluid-retention is eaten, and hinders overstrain, malaria flatulence due to stagnation of QI Card, edema distension gathers, cough due to fluid-retention, vomiting regurgitation, cholera, and blood-retention is pained, gastric abscess, hypochondriac pain, numbness flaccidity dizziness, heavy sensation of the body, no Can eat, jaundice.”
Radix indigoferae incarnatae: acrid in the mouth, acid, property is put down;Return liver, kidney channel.Reason traumatic injury, reuniting the fractured tendons and bones, the meridian dredging, dissipating blood stasis amasss, detumescence pain.Control and fall Beat damage, the long-pending stasis of blood, Fengshi Guanjie pain.
Rhizoma Dioscoreae Cirrhosae: bitter in the mouth, cool in nature.Promoting blood circulation and hemostasis, regulating QI to relieve pain, heat-clearing and toxic substances removing.Main hemoptysis, spitting of blood, hematemesis, epistaxis, hematuria, Have blood in stool, metrorrhagia, menoxenia, dysmenorrhea, amenorrhea, puerperal abdonimal pain, abdominal distention, erputive abdominal disease, toxic-heat and blood stasis, watery diarrhea, arthralgia, Treating swelling and pain by traumatic injury, furuncle, herpes zoster, traumatic hemorrhage." Guizhou side among the people medicine collection " carries: " dysentery relieving disease.Control puerperal abdonimal pain, tympanites;Again Control asthma.”
Rhizoma Acori Calami: acrid in the mouth, hardship, warm in nature;GUIXIN, liver, stomach warp;Waking up the patient from unconsciousness by dissipating phlegm, dehumidify stomach invigorating, killing parasites for relieving itching.Main syncope due to accumulation of phlegm dusk Fan, apoplexy, epilepsy, to palpitate with fear forgetful, Hiccough and deaf, abdominal pain due to retention of food, dysentery has loose bowels, rheumatalgia, eczema, scabies.
Herba Erysimi Cheiranthoidis: bitter in the mouth, pungent, cold in nature;Attach to the lung and stomach meridians.Invigorating the spleen and regulating the stomach, diuresis heart tonifying.Main incoordination between the spleen and stomach, accumulation of food in the stomach and intes tine due to indigestion, and The edema of heart failure." Chinese herbal medicine is commonly used in Tibet " carries: " clearing away heat from blood, antitussive, heart tonifying.Being in harmony the heating of empty infections, pulmonary tuberculosis is coughed, for a long time Sick cardianeuria, can solve meat poisoning.”
Fructus nephelii topengii: sweet in the mouth, acid, warm in nature;Return spleen, stomach warp.Cold expelling, dysentery relieving, removing toxic substances.Main dysentery, trusted subordinate's cold type of pain, skin infection." Luchuan Book on Chinese herbal medicine " carry: " anti-inflammation and sterilization.Control stomatitis, dysentery, wash ulcer.”
The present invention compared with prior art, has the advantages that
Selected by Chinese medicine of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has Soothing liver-QI is invigorated blood circulation, effect of reducing swelling and alleviating pain, detoxicating and resolving stagnation of pathogens, is used for nursing postoperative anesthetis untoward reaction and has unique curative effect, and becomes This is relatively low, safe and reliable, without any side effects, provides safety guarantee for successful surgery, and special effect is practical, wide on clinic General popularization and application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine effective ingredient of the present invention forms and weight is:
The preparation method of Chinese medicine of the present invention, comprises the following steps that:
(1) Fel python, Herba Solani Surattensis, Radix Stephaniae hemandifoliae, Rhizoma Acori Calami and Herba Erysimi Cheiranthoidis are put into container, carry out pulverization process, grind into powder, obtain Cross the fine powder of 180 mesh, standby;
(2) Herba Pugionii Cornuti, Fructus Melodini Suaveolentis, Massa Medicata Fermentata, Radix indigoferae incarnatae, Rhizoma Dioscoreae Cirrhosae and Fructus nephelii topengii are cleaned, put into container, add 8~10 times amount Distilled water, after soaking 5~6 hours, boils 3~4 hours, extracts;Again add 6~8 times amount distilled water, boil 2~3 hours, Extract;Finally, add 4~6 times amount distilled water, heated and boiled 1~2 hours, extract;Merge three extracting solution, filter, obtain filter Liquid, standby;
(3) moccasin tree and Fructus Mori are cleaned, immerse 5 times amount 80% alcohol solution dipping 1~2 hours, heating extraction 3 Hour, reclaim ethanol, filter, obtain filtrate, standby;
(4) Herba Carpesii Cernui, Bulbus Lycoridis Radiatae and Radix embeliae laetae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby;
(5) fine powder obtained by above-mentioned steps (1)~(4), filtrate and juice are mixed, and add 10~12 times amount Distilled water, after stirring and dissolving is uniform, heated and boiled 0.5 hour, stand 1 hour, extract and filter, obtain liquid medicine, liquid medicine fill is sealed Deposit, obtain the described Chinese medicine for nursing postoperative anesthetis untoward reaction.
Usage and dosage: used for intravenous injection, extracts liquid medicine 20~25ml, must not exceed 50ml every time, and frequency injection must not surpass Crossing 3 times, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of Chinese medicine effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Chinese medicine effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Chinese medicine effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 5
The raw material of Chinese medicine effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
As for nursing the Chinese medicine of postoperative anesthetis untoward reaction, select anaesthesia process occurs bad instead Answering patient 220 example clinical observation, patient is randomly divided into treatment group and matched group two groups, treatment group 110 example, wherein male 55 example, Women 55 example, age 20~67 years old, 43.5 years old mean age, average course of disease 3 days;Matched group 110 example, wherein male 55 example, female Property 55 examples, age 21~68 years old, 44.5 years old mean age, average course of disease 3 days.
Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparable Property.
2, medicament selection:
Treatment group uses Chinese medicine of the present invention, intravenous injection, extraction liquid medicine 20~25 milligrams, must not exceed every time 50ml, frequency injection must not exceed 3 times, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group uses propofol, intravenous injection, the adult patient less than 55 years old of most of ages, takes around The propofol of 2.0~2.5 mgs/kg, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: the untoward reaction symptom that anesthesia causes all disappears, and physical recovery is as usual.
(2) effective: the untoward reaction symptom that anesthesia causes substantially alleviates, and health is clearly better.
(3) effective: the untoward reaction symptom that anesthesia causes has alleviated, and health has taken a turn for the better.
(4) invalid: by anaesthetizing the untoward reaction symptom caused without alleviating or increasing the weight of after treatment.
4, result:
Select in the treatment group of Chinese medicine of the present invention, cure 77 examples, effective 24 examples, effective 8 examples, invalid 1 example, cure Rate 70%, total effective rate 99.1%.
Matched group is cured 68 examples, effective 19 examples, effective 10 examples, invalid 13 examples, cure rate 61.8%, total effective rate 88.2%.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, model, man, 23 years old, Anhui people from Chizhou City.The left lower limb of patient scratches, wound about 3 centimetres, carries out primary haemostasis, uses After anesthetics pain relieving, sewing up further, after stitching, there is untoward reaction in patient, injects Chinese medicine of the present invention treatment, injects 1 After secondary, above-mentioned symptom substantially alleviates, and after injecting 2 times, above-mentioned symptom disappears, and follows up a case by regular visits to without recurrence after 3 days.
2, side certain, female, 30 years old, people from Shiyan, Hubei.Patient's cesarean is in hospital, and uses anesthetis, anaesthetizes, postoperative patient The untoward reaction such as nausea and vomiting occur, doctor gives and injects Chinese medicine of the present invention treatment, and after injecting 1 time, above symptom is obvious Alleviating, after continuing to inject 1 time, above-mentioned symptom disappears, recovery from illness.
3, stone, man, 37 years old, Shanwei people.Swelling and ache after patient's right ancon traumatic injury, limitation of activity, with right capitulum radii Fracture, physical examination of being admitted to hospital: right forearm spinfunction is limited, right ancon swelling, tenderness.Anaesthetize descending at brachial plexus nerve after being admitted to hospital Right fracture of capitulum radii open reduction Kirschner wire internal fixation operation, postoperative because of anesthesia occur that untoward reaction, doctor give the present invention Chinese medicine is treated, and after injecting 1 time, symptom has been alleviated, and after injecting 2 times, symptom all disappears, recovery from illness.
4, Yao, man, 29 years old, Heihe In The Heilongjiang River people.Patient removes hospital admission because of abdominal pain, is diagnosed as through ultrasound diagnosis Acute appendicitis, needs operative treatment at once, operation consent injecting anesthetic medicine, and postoperative discovery patient has untoward reaction to anesthetics, Injecting Chinese medicine of the present invention treatment, after injecting 1 time, symptom substantially alleviates, after continuing to inject 1 time, and transference cure, recovery from illness.
5, Tan, female, 51 years old, people from Siping.Patient's prolapse of lumbar intervertebral disc companion's spinal canal stenosis, need to carry out Wicresoft's acicular hook and dial Pine art treatment, uses anesthetis, carries out Wicresoft's acicular hook and dial pine art treatment operation after 15 minutes, painless in art, postoperative appearance Untoward reaction, doctor gives Chinese medicine of the present invention treatment, and after injecting 1 time, untoward reaction is substantially alleviated, and continues injection 1 time After, untoward reaction all disappears, and remains in a hospital under observation and does not recurs.
6, Liao, female, 33 years old, people from Huangpu District, Shanghai.There is a lump inside patient's right breast, need to excise, use After anesthetics, untoward reaction occur, doctor gives after injecting Chinese medicine of the present invention treatment, and symptom all disappears, recovery from illness.

Claims (5)

1. the Chinese medicine being used for nursing postoperative anesthetis untoward reaction, it is characterised in that: make described Chinese medicine injection The raw material of agent effective ingredient forms and parts by weight are:
Fel python 35~59 parts of Herba Pugionii Cornutis 34~58 parts of moccasin trees 33~33~57 parts of 57 portions of Fructus Moris
Fructus Melodini Suaveolentis 32~56 parts of Herba Carpesii Cernui 32~31~55 parts of Herba Solani Surattensiss of 56 portions of Bulbus Lycoridis Radiataes 30~54 parts
Radix Stephaniae hemandifoliae 30~54 parts of Radix embeliae laetae 29~53 parts of Massa Medicata Fermentata 28~52 parts of Radix indigoferae incarnataes 28~52 parts
Rhizoma Dioscoreae Cirrhosae 28~52 parts of Rhizoma Acori Calami 27~50 parts of Herba Erysimi Cheiranthoidiss 24~48 parts of Fructus nephelii topengii 24~48 parts.
A kind of Chinese medicine for nursing postoperative anesthetis untoward reaction the most according to claim 1, its feature exists In: make described Chinese medicine effective ingredient raw material composition and parts by weight be:
Fel python 39~55 parts of Herba Pugionii Cornutis 38~54 parts of moccasin trees 37~37~53 parts of 53 portions of Fructus Moris
Fructus Melodini Suaveolentis 36~52 parts of Herba Carpesii Cernui 36~35~51 parts of Herba Solani Surattensiss of 52 portions of Bulbus Lycoridis Radiataes 34~50 parts
Radix Stephaniae hemandifoliae 34~50 parts of Radix embeliae laetae 33~49 parts of Massa Medicata Fermentata 32~48 parts of Radix indigoferae incarnataes 32~48 parts
Rhizoma Dioscoreae Cirrhosae 32~48 parts of Rhizoma Acori Calami 30~46 parts of Herba Erysimi Cheiranthoidiss 28~44 parts of Fructus nephelii topengii 28~44 parts.
A kind of Chinese medicine for nursing postoperative anesthetis untoward reaction the most according to claim 1, its feature exists In: make described Chinese medicine effective ingredient raw material composition and parts by weight be:
Fel python 43~51 parts of Herba Pugionii Cornutis 42~50 parts of moccasin trees 41~41~49 parts of 49 portions of Fructus Moris
Fructus Melodini Suaveolentis 40~48 parts of Herba Carpesii Cernui 40~39~47 parts of Herba Solani Surattensiss of 48 portions of Bulbus Lycoridis Radiataes 38~46 parts
Radix Stephaniae hemandifoliae 38~46 parts of Radix embeliae laetae 37~45 parts of Massa Medicata Fermentata 36~44 parts of Radix indigoferae incarnataes 36~44 parts
Rhizoma Dioscoreae Cirrhosae 36~44 parts of Rhizoma Acori Calami 34~42 parts of Herba Erysimi Cheiranthoidiss 32~40 parts of Fructus nephelii topengii 32~40 parts.
A kind of Chinese medicine for nursing postoperative anesthetis untoward reaction the most according to claim 1, its feature exists In: make described Chinese medicine effective ingredient raw material composition and parts by weight be:
45 parts of 47 parts of Herba Pugionii Cornutis of Fel python, 45 portions of Fructus Moris of 46 parts of moccasin trees
44 parts of Herba Carpesii Cernui of Fructus Melodini Suaveolentis, 43 parts of Herba Solani Surattensiss of 44 portions of Bulbus Lycoridis Radiataes 42 parts
42 parts of Radix embeliae laetae of Radix Stephaniae hemandifoliae, 40 parts of Radix indigoferae incarnataes of 41 parts of Massa Medicata Fermentata 40 parts
40 parts of Rhizoma Acori Calami of Rhizoma Dioscoreae Cirrhosae, 36 parts of Fructus nephelii topengii of 38 parts of Herba Erysimi Cheiranthoidiss 36 parts.
5. the system being used for nursing the Chinese medicine of postoperative anesthetis untoward reaction as described in any one of Claims 1 to 4 Preparation Method, it is characterised in that: comprise the following steps that:
(1) Fel python, Herba Solani Surattensis, Radix Stephaniae hemandifoliae, Rhizoma Acori Calami and Herba Erysimi Cheiranthoidis are put into container, carry out pulverization process, grind into powder, obtained The fine powder of 180 mesh, standby;
(2) Herba Pugionii Cornuti, Fructus Melodini Suaveolentis, Massa Medicata Fermentata, Radix indigoferae incarnatae, Rhizoma Dioscoreae Cirrhosae and Fructus nephelii topengii are cleaned, put into container, add the distillation of 8~10 times amount Water, after soaking 5~6 hours, boils 3~4 hours, extracts;Again add 6~8 times amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times amount distilled water, heated and boiled 1~2 hours, extract;Merge three extracting solution, filter, obtain filtrate, standby With;
(3) moccasin tree and Fructus Mori are cleaned, immerse 5 times amount 80% alcohol solution dipping 1~2 hours, heating extraction 3 hours, Reclaim ethanol, filter, obtain filtrate, standby;
(4) Herba Carpesii Cernui, Bulbus Lycoridis Radiatae and Radix embeliae laetae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby;
(5) fine powder obtained by above-mentioned steps (1)~(4), filtrate and juice are mixed, and add the distillation of 10~12 times amount Water, after stirring and dissolving is uniform, heated and boiled 0.5 hour, stand 1 hour, extract and filter, obtain liquid medicine, liquid medicine fill is sealed up for safekeeping, i.e. The Chinese medicine for nursing postoperative anesthetis untoward reaction described in.
CN201610407136.3A 2016-06-12 2016-06-12 Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof Pending CN105920270A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610407136.3A CN105920270A (en) 2016-06-12 2016-06-12 Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610407136.3A CN105920270A (en) 2016-06-12 2016-06-12 Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105920270A true CN105920270A (en) 2016-09-07

Family

ID=56832846

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610407136.3A Pending CN105920270A (en) 2016-06-12 2016-06-12 Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105920270A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432369A (en) * 2013-08-29 2013-12-11 王冉 Medicament for treating narcotic adverse reactions
CN104189849A (en) * 2014-09-22 2014-12-10 宋吉玲 Traditional Chinese medicine composition for preventing adverse reaction after anesthesia and preparation method of traditional Chinese medicine composition
CN104524286A (en) * 2014-12-19 2015-04-22 刘瑞全 Traditional Chinese medicinal liquid for treating adverse reaction after anesthesia and preparation method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432369A (en) * 2013-08-29 2013-12-11 王冉 Medicament for treating narcotic adverse reactions
CN104189849A (en) * 2014-09-22 2014-12-10 宋吉玲 Traditional Chinese medicine composition for preventing adverse reaction after anesthesia and preparation method of traditional Chinese medicine composition
CN104524286A (en) * 2014-12-19 2015-04-22 刘瑞全 Traditional Chinese medicinal liquid for treating adverse reaction after anesthesia and preparation method

Similar Documents

Publication Publication Date Title
CN103920051B (en) A kind of medicine and preparation method for the treatment of infantile malnutrition
CN103800800B (en) A kind of medicine for adult respiratory distress syndrome nursing and preparation method
CN103961634A (en) Traditional Chinese medicine preparation for treating nausea and vomiting caused by anesthesia and preparation method thereof
CN103768457B (en) A kind of medicine and preparation method for the treatment of infantile anorexia
CN103394030B (en) Traditional Chinese medicine composition for treating depressed liver and deficient spleen
CN103893613A (en) Medicament for treating canker sore and preparation method thereof
CN103393943A (en) Traditional Chinese medicine composition for treating sequela of cerebral infarction
CN103877490B (en) A kind of Chinese medicine preparation and preparation method for the treatment of prolapse of lumbar intervertebral disc
CN105362914A (en) Traditional Chinese medicinal composition for treating chronic gastritis
CN103736031A (en) Drug for treating viral hepatitis type C and preparation method thereof
CN103933402A (en) Traditional Chinese medicine preparation for treating brain tumor and preparation method
CN105920270A (en) Traditional Chinese medicine injection applied to nursing postoperative anesthetic adverse reactions and preparation method thereof
CN102335314B (en) Chinese medicinal composition for treating stomach diseases
CN103800685B (en) A kind of Chinese medicine preparation and preparation method for the treatment of prolapse of lumbar intervertebral disc
CN102641442B (en) Traditional Chinese medicine preparation for treating recurrent aphthae
CN104547447A (en) Traditional Chinese medicine liquid for treating adverse reaction of anesthetic and preparation method of traditional Chinese medicine liquid
CN105012737A (en) Medicine for treating adverse responses due to anaesthetics and preparation method thereof
CN105250871A (en) Traditional Chinese medicine composition for treating stomach illness and preparing method thereof
CN104784588A (en) Traditional Chinese medicine preparation for treating nerve headache and preparation method
CN104435503A (en) Traditional Chinese medicine anesthetic special for pre-operation and preparation method
CN104491364A (en) Pill for treating chronic lymphocytic thyroiditis and preparation method
CN114601900A (en) Formula and preparation method of infant height-increasing spleen-tonifying intelligence-developing paste
CN117363446A (en) Noon health-preserving wine
CN109200194A (en) A kind of medicine pill and preparation method thereof for treating the postoperative low fever of obstetrics
CN108042722A (en) A kind of Chinese medicine for treating cloudy closed form apoplexy

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160907