CN105919903B - A kind of freckle-removing mask and freckle-removing mask preparation method - Google Patents
A kind of freckle-removing mask and freckle-removing mask preparation method Download PDFInfo
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- CN105919903B CN105919903B CN201610494798.9A CN201610494798A CN105919903B CN 105919903 B CN105919903 B CN 105919903B CN 201610494798 A CN201610494798 A CN 201610494798A CN 105919903 B CN105919903 B CN 105919903B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/985—Skin or skin outgrowth, e.g. hair, nails
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
Abstract
The invention discloses a kind of freckle-removing masks and preparation method thereof, by plant antiseptic agent composition, polyvinyl alcohol crosslinked polymer, ethyl alcohol, papain, donkey-hide gelatin, ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract, ginkgo biloba p.e, Baical Skullcap root P.E, stephania tetrandra extract, carbomer, deionized water composition.The freckle-removing mask of the present invention not only has improved safe freckle effect, also has extended shelf life of products.
Description
Technical field
The invention belongs to cosmetic additive agent technical fields, and in particular to a kind of freckle-removing mask and freckle-removing mask preparation side
Method.
Background technology
Containing abundant amino acid, protein, collagen, vitamin, moisture etc. in cosmetics, these maintenance ingredients are simultaneously
It is bacterium, microbial growth " Nutrient medium ", it is therefore desirable to preservative is added in cosmetics so as to maintenance for a long time
The quality of cosmetic.In general, the moisture of cosmetics is higher, and rotten possibility is bigger, more needs to add preservative.Face
Film is a kind of product that water content is larger in cosmetics, therefore the addition of preservative is also more.Since common chemical synthesis is anti-
Rotten agent has higher irritation to skin, and the natural antiseptic agent non-stimulated to skin has been favored by people.But natural antiseptic agent
The color is too dark and raw material is highly seasoned for a part for raw material, broad spectrum antibacterial is poor compared with chemical preservative, and the activity in plant extracts
Ingredient is low to the physical stability of light, heat, oxygen, its antiseptic activity cannot be fully kept during circulation, limits natural anti-
The use of rotten agent.
In numerous skin problems, it is color spot to cause a problem of quite big puzzlement to people.The producing cause of color spot
Have following several：Life stress is big, hormone imbalance, metabolism ultraviolet radiation unsmooth, in daylight, cosmetics make
With improper etc..Present nti-freckle product is palliative based on chemical addition agent, and rebound is easy after deactivating, and is used for a long time
Skin naturally elasticity and gloss can be damaged again.Some people there is also the phenomenon that cutaneous anaphylaxis, skin ageing, to skin
It causes centainly to injure, pain and heavy financial burden is brought to consumer.
Invention content
One of the technical problem to be solved in the present invention is to provide a kind of plant antiseptic agent composition, plant antiseptic agent combination
The main active of object comes from natural plants, the butanediol and pentanediol of collaboration bacteriostasis has been equipped with, without routinizing
Preservative is learned, it is non-stimulated to human body, have no toxic side effect, allergy will not be led to, and promote mutually between each ingredient, collaboration plays
Effect, can effective restraining and sterilizing bacteria；The invention solves another problem be to provide and a kind of containing plant antiseptic agent composition
Freckle-removing mask, the main component of the facial mask is Chinese medical extract, can not only play safe freckle effect, also extend product
Shelf-life.
One aspect of the present invention provides a kind of plant antiseptic agent composition, and the composition has been equipped with by active components of plants
The butanediol and pentanediol for cooperateing with bacteriostasis are composed, and the active components of plants includes that long and thin hot pepper berry extract, Korea are white
Head father-in-law extract, must extractive of usnea, the long and thin hot pepper berry extract, pasque flower extract, must extractive of usnea weight
Proportioning is 2：1~3：1~3；The active components of plants, butanediol, pentanediol weight proportion be 0.03~3：5~10：3~
5；
The long and thin hot pepper berry extract is prepared as follows：According to the ratio of every gram of prickly ash berries 25mL Extraction solvent,
A concentration of 80% ethyl alcohol Extraction solvent is added in cleaning the prickly ash berries after drying, 80~85 ° keep the temperature 1~2h of refluxing extraction,
Cooling, centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The pasque flower extract is prepared as follows：According to every gram of pasque flower 25mL Extraction solvent
Ratio, is added a concentration of 80% ethyl alcohol Extraction solvent in cleaning the pasque flower after drying, and 80~85 ° of heat preservation reflux carry
1~2h, cooling, centrifugation, filtering, filtered extracting solution is taken to be concentrated under reduced pressure, freeze-drying preserves；
The palpus extractive of usnea is prepared as follows：According to every gram must sunglo 25mL Extraction solvents ratio,
Clean be added in the palpus sunglo after drying a concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extraction 1~2h are cold
But it, centrifuges, filter, filtered extracting solution is concentrated under reduced pressure, and freeze-drying preserves；
Another aspect of the present invention provides a kind of freckle-removing mask, and containing plant antiseptic agent composition, the composition is by plant
Active constituent has been equipped with the butanediol of collaboration bacteriostasis and pentanediol is composed, and the active components of plants includes prickly ash berries
Extract, pasque flower extract, palpus extractive of usnea, the long and thin hot pepper berry extract, pasque flower extract, palpus sunglo
The weight proportion of extract is 2：1~3：1~3；With the total weight of facial mask, weight of the active components of plants in facial mask
Percentage is 0.03~3%, and weight percent of the butanediol in facial mask is 5~10%, quality hundred of the pentanediol in facial mask
Divide than being 3~5%；
The long and thin hot pepper berry extract is prepared as follows：According to the ratio of every gram of prickly ash berries 25mL Extraction solvent,
A concentration of 80% ethyl alcohol Extraction solvent is added in cleaning the prickly ash berries after drying, 80~85 ° keep the temperature 1~2h of refluxing extraction,
Cooling, centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The pasque flower extract is prepared as follows：According to every gram of pasque flower 25mL Extraction solvent
Ratio, is added a concentration of 80% ethyl alcohol Extraction solvent in cleaning the pasque flower after drying, and 80~85 ° of heat preservation reflux carry
1~2h, cooling, centrifugation, filtering, filtered extracting solution is taken to be concentrated under reduced pressure, freeze-drying preserves；
The palpus extractive of usnea is prepared as follows：According to every gram must sunglo 25mL Extraction solvents ratio,
Clean be added in the palpus sunglo after drying a concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extraction 1~2h are cold
But it, centrifuges, filter, filtered extracting solution is concentrated under reduced pressure, and freeze-drying preserves；
The other components and weight percentage of the facial mask are as follows：
Polyvinyl alcohol crosslinked polymer 10~15%
Ethyl alcohol 3~5%
Papain 0.6~1%
Donkey-hide gelatin 4~10%
Ginseng root extract 0.5~0.8%
Leonurus extract 5~8%
Licorice root extract 5~8%
Kuh-seng root extract 5~8%
Ginkgo biloba p.e 0.5~5%
Baical Skullcap root P.E 2~5%
Stephania tetrandra extract 0.1~1%
Carbomer 0.05~0.2%
Remaining is deionized water.
Effect of the said components in prescription is as follows：
Polyvinyl alcohol crosslinked polymer：Film forming agent；
Ethyl alcohol：Anti-inflammatory, convergence pore；
Papain：Abbreviation papain is extracted from papaya fruit and is obtained, and papain is easy to and forms the black of color spot
Copper ion in pigment forms complex compound, reduces the formation of melanin and removes the melanin of color spot, and the three of pawpaw enzyme hydrolysis
Titanium substance can directly inhibit to form the tyrosine of melanin activity, Free Radical be eliminated, to achieve the effect that whitening spot-removing；
Donkey-hide gelatin：Skin collagen can be supplemented, the formation of melanin is inhibited, moreover it is possible to body cell be stimulated to generate glutathione
And superoxide dismutase, and superoxide dismutase can scavenging activated oxygen, have antitumor, anti-aging, whitening, nti-freckle
The effect of；
Ginseng root extract：Wrinkle is comforted with extremely strong oxidation resistance, and with flat, promotes blood circulation, enhances skin
Skin nutrition accelerates the multi-efficiencies such as metabolism, can effectively improve skin, prevent skin dehydration, hardening, corrugation while ginseng
Active material also has the reducing property for inhibiting melanin, keeps skin pure white smooth；
Leonurus extract：It is micro- containing selenium and manganese etc., it can be anti-oxidant, anti-aging；
Licorice root extract：By inhibiting a variety of enzyme (such as tyrosinases and dopachrome change in melanin forming process
Enzyme) activity, achieve the effect that whitening, nti-freckle；
Kuh-seng root extract：Whitening, anti-inflammatory, anti-acne, antibacterial etc.；
Ginkgo biloba p.e：The brass ingredient contained in ginkgo leaf can hinder formation and calmness of the pigment in genuine piece layer,
Have the function that skin whitening and prevention color spot；And brass ingredient is the street cleaner of free radical, can protect corium confluent monolayer cells, change
Kind blood circulation, prevents cell from generating wrinkle by oxidation；
Baical Skullcap root P.E：The flavone compound contained in Baical Skullcap root P.E can absorb ultraviolet light, scavenging activated oxygen, again
The generation that can inhibit melanin has the effect of anti-aging, whitening, nti-freckle；
Stephania tetrandra extract：Antiallergy；
Carbomer：Thickener.
Further, the pH value of the freckle-removing mask is adjusted to 5~6 with 10% potassium hydroxide solution, makes the acid of facial mask
Basicity is close with skin.
Further, the ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract, ginkgo
Leaf extract, Baical Skullcap root P.E raw material keep the temperature 1~2h of refluxing extraction with 80% ethyl alcohol respectively, centrifugation, filtered carries filtering
It takes liquid to be concentrated under reduced pressure into 5 times of concentration and obtains extract.
The present invention also provides a kind of preparation methods of freckle-removing mask, include the following steps：
(1) polyvinyl alcohol crosslinked polymer is added in deionized water, is heated to 80 ° of dissolvings,；
(2) above-mentioned temperature is kept, carbomer is slowly added into (1) while stirring, until carbomer complete swelling, fully divides
It dissipates in (1)；
(3) pH to 5~6 is adjusted with 10% potassium hydroxide solution, starts to cool down, when temperature is down to 40 °, ethyl alcohol is added
(2) in stirring, then add donkey-hide gelatin, ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract,
Ginkgo biloba p.e, Baical Skullcap root P.E, stephania tetrandra extract, plant antiseptic agent composition stir evenly up to facial mask liquid.
The advantage of the invention is that：
1, plant antiseptic agent composition of the invention is equipped with butanediol using natural plant active component and pentanediol combines
It forms, is free of conventional chemical preservative, it is non-stimulated to human body, have no toxic side effect, allergy will not be led to, wherein contain in prickly ash berries
There are many unsaturated fatty acid, there is local anaesthesia and fight Escherichia coli, shigella dysenteriae, corynebacteria, dermatophyte etc.
Effect；Pasque flower have it is antitumor, enhancing immune function, anti-inflammatory, resisting pathogenic microbes, anti parasitic, liver protection, toxicity and
The effects that treatment endotoxemia etc. is made；Palpus sunglo is a kind of natural extract from lichens tree, its main component sunglo
Acid is considered as a kind of potent antibiotic and antiseptic, is prevented carefully as natural antiseptic agent in cosmetics and personal care articles
Bacterium and fungi growth, it has effects that broad-spectrum antiseptic, is believed to effectively antagonize all gram-positive bacterias and pulmonary tuberculosis
Bacterium.Long and thin hot pepper berry extract, pasque flower extract, palpus extractive of usnea are combined, promoted mutually between each ingredient,
Collaboration plays effect, can effective restraining and sterilizing bacteria.Although three of the above active components of plants can not be with restraining and sterilizing bacteria, effect
It is most strong, therefore butanediol and pentanediol have been compounded in the plant antiseptic agent composition of the present invention, keep bactericidal and bacteriostatic effect best.
2, the plant antiseptic agent composition is applied in the freckle-removing mask that active ingredient of Chinese herbs develops by the present invention,
The effect for not only reached safe nti-freckle, also makes freckle effect be enhanced, and extends the shelf-life of product.
3, freckle-removing mask of the invention is by papain, donkey-hide gelatin, ginseng root extract, Leonurus extract, licorice
Extract, kuh-seng root extract, ginkgo biloba p.e, each active constituent of Baical Skullcap root P.E configure by a certain percentage, to black
Pigment has coordinate repression, while also having the effect of anti-aging, whitening.
Specific implementation mode
It is the non-limiting examples of the present invention below, these embodiments are only given for illustrative purposes, not
It can be interpreted as limitation of the invention.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creation
Property labour under the premise of the every other embodiment that is obtained, shall fall within the protection scope of the present invention.
Embodiment one
A kind of plant antiseptic agent composition, including long and thin hot pepper berry extract, pasque flower extract, palpus extractive of usnea,
The long and thin hot pepper berry extract, pasque flower extract, must extractive of usnea weight proportion be 1：1：1；
The long and thin hot pepper berry extract is prepared as follows：According to the ratio of every gram of prickly ash berries 25mL Extraction solvent,
A concentration of 80% ethyl alcohol Extraction solvent is added in cleaning the prickly ash berries after drying, 80~85 ° keep the temperature 1~2h of refluxing extraction,
Cooling, centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The pasque flower extract is prepared as follows：According to every gram of pasque flower 25mL Extraction solvent
Ratio, is added a concentration of 80% ethyl alcohol Extraction solvent in cleaning the pasque flower after drying, and 80~85 ° of heat preservation reflux carry
1~2h, cooling, centrifugation, filtering, filtered extracting solution is taken to be concentrated under reduced pressure, freeze-drying preserves；
The palpus extractive of usnea is prepared as follows：According to every gram must sunglo 25mL Extraction solvents ratio,
Clean be added in the palpus sunglo after drying a concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extraction 1~2h are cold
But it, centrifuges, filter, filtered extracting solution is concentrated under reduced pressure, and freeze-drying preserves.
Embodiment two
A kind of plant antiseptic agent composition has been equipped with the butanediol and pentanediol of collaboration bacteriostasis by active components of plants
Be composed, the active components of plants include long and thin hot pepper berry extract, pasque flower extract, must extractive of usnea, it is described
Long and thin hot pepper berry extract, pasque flower extract, must extractive of usnea, butanediol, pentanediol weight proportion be 1：1：1：6：
4；
The preparation method and one phase of embodiment of the long and thin hot pepper berry extract, pasque flower extract, palpus extractive of usnea
Together.
Embodiment three
A kind of freckle-removing mask, containing plant antiseptic agent composition, the composition includes long and thin hot pepper berry extract, towards Common Squill Bulb
Father-in-law's extract, palpus extractive of usnea, with the total weight of facial mask, weight percent of the long and thin hot pepper berry extract in facial mask is 1%,
Weight percent of the pasque flower extract in facial mask is 1%, and weight percent of the palpus extractive of usnea in facial mask is
1%；
The long and thin hot pepper berry extract is prepared as follows：According to the ratio of every gram of prickly ash berries 25mL Extraction solvent,
Clean be added in the prickly ash berries after drying a concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extraction 1~2h are cold
But it, centrifuges, filter, filtered extracting solution is concentrated under reduced pressure, and freeze-drying preserves；
The pasque flower extract is prepared as follows：According to every gram of pasque flower 25mL Extraction solvent
Ratio, is added a concentration of 80% ethyl alcohol Extraction solvent in cleaning the pasque flower after drying, and 80~85 ° of heat preservation reflux carry
1~2h, cooling, centrifugation, filtering, filtered extracting solution is taken to be concentrated under reduced pressure, freeze-drying preserves；
The palpus extractive of usnea is prepared as follows：According to every gram must sunglo 25mL Extraction solvents ratio,
Clean be added in the palpus sunglo after drying a concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extraction 1~2h are cold
But it, centrifuges, filter, filtered extracting solution is concentrated under reduced pressure, and freeze-drying preserves；
The other components and weight percentage of the facial mask are as follows：
Polyvinyl alcohol crosslinked polymer 10~15%
Ethyl alcohol 3~5%
Papain 0.6~1%
Donkey-hide gelatin 4~10%
Ginseng root extract 0.5~0.8%
Leonurus extract 5~8%
Licorice root extract 5~8%
Kuh-seng root extract 5~8%
Ginkgo biloba p.e 0.5~5%
Baical Skullcap root P.E 2~5%
Stephania tetrandra extract 0.1~1%
Carbomer 0.05~0.2%
Remaining is deionized water.
The pH value of the freckle-removing mask is adjusted to 5~6 with 10% potassium hydroxide solution.
The ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract, ginkgo biloba p.e,
The raw material of Baical Skullcap root P.E keeps the temperature 1~2h of refluxing extraction, centrifugation, filtering, the decompression of filtered extracting solution with 80% ethyl alcohol respectively
It is concentrated into 5 times of concentration and obtains extract.
Example IV
A kind of freckle-removing mask, containing plant antiseptic agent composition, the composition has been equipped with collaboration by active components of plants
The butanediol and pentanediol of bacteriostasis are composed, and the active components of plants includes long and thin hot pepper berry extract, pasque flower
Extract, palpus extractive of usnea, with the total weight of facial mask, weight percent of the long and thin hot pepper berry extract in facial mask is 1%, court
Weight percent of the Common Squill Bulb father-in-law's extract in facial mask is 1%, and weight percent of the palpus extractive of usnea in facial mask is
1%, weight percent of the butanediol in facial mask is 6%, and mass percent of the pentanediol in facial mask is 4%；
The long and thin hot pepper berry extract, pasque flower extract, must extractive of usnea preparation method and embodiment one or
Embodiment three is identical, and the other components and weight percentage of the facial mask are identical as embodiment three；
The pH value of the freckle-removing mask is adjusted to 5~6 with 10% potassium hydroxide solution.
Ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract, ginkgo biloba p.e, radix scutellariae
The raw material of extract keeps the temperature 1~2h of refluxing extraction with 80% ethyl alcohol respectively, and centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure
Extract is obtained to 5 times of concentration.
Embodiment five
A kind of preparation method of freckle-removing mask, includes the following steps：
(1) polyvinyl alcohol crosslinked polymer is added in deionized water, is heated to 80 ° of dissolvings,；
(2) above-mentioned temperature is kept, carbomer is slowly added into (1) while stirring, until carbomer complete swelling, fully divides
It dissipates in (1)；
(3) pH to 5~6 is adjusted with 10% potassium hydroxide solution, starts to cool down, when temperature is down to 40 °, ethyl alcohol is added
(2) in stirring, then add donkey-hide gelatin, ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract,
Ginkgo biloba p.e, Baical Skullcap root P.E, stephania tetrandra extract, plant antiseptic agent composition stir evenly up to facial mask liquid.
Embodiment six
Bacteriostatic experiment
1, experiment material
Sample 1：According to freckle-removing mask prepared by the method for embodiment five, containing polyvinyl alcohol crosslinked polymer 12%,
Ethyl alcohol 3%, papain 1%, donkey-hide gelatin 10%, ginseng root extract 0.8%, Leonurus extract 5%, licorice root extract
5%, kuh-seng root extract 6%, ginkgo biloba p.e 3%, Baical Skullcap root P.E 4%, stephania tetrandra extract 0.8%, carbomer
0.1%, surplus is deionized water；
Sample 2：According to freckle-removing mask prepared by the method for embodiment five, whole compositions containing sample 1 contain with percentage
Amount also contains long and thin hot pepper berry extract 1%, pasque flower extract 1%, palpus extractive of usnea 1%；
Sample 3：According to freckle-removing mask prepared by the method for embodiment five, whole compositions containing sample 1 contain with percentage
Amount is outer, also contains butanediol 6%, pentanediol 4%；
Sample 4：According to freckle-removing mask prepared by the method for embodiment five, whole compositions containing sample 1 contain with percentage
Amount is outer, also contains long and thin hot pepper berry extract 1%, pasque flower extract 1%, palpus extractive of usnea 1%；Butanediol 6%, penta 2
Alcohol 4%.
2, experimental method
Bacterium (staphylococcus aureus, Escherichia coli) is inoculated into lecithin Tween 80-nutrient agar respectively
Inclined-plane is cultivated for 24 hours under 37 °；Mould (candida albicans bacterium, aspergillus niger) is inoculated with Cha Shi fluid nutrient mediums, is cultivated under 25 °
5d.The appropriate four kinds of bacterium colonies of picking respectively, are diluted to certain density bacteria suspension, bacterial suspension concentration is with sterile saline
1.0×106cfu/g。
Above-mentioned four kinds of bacteria suspensions are coated on nutrient agar panel respectively with aseptic cotton carrier, lawn is made, then takes diameter
For the sterilizing filter paper disk of 3cm, after uniformly picking facial mask made of 3 kinds of samples respectively, then it is attached to four kinds of different bacteria suspensions respectively
On manufactured tablet, bacterium and mycotic culture 7d observe result.
3, evaluation method
Paper disk method bacteriostatic diameter >=10mm is effective, and bacteriostatic diameter ＜ 10mm are invalid.
4, experimental result is shown in Table 1
1 paper disk method fungistatic effect of table
As shown in Table 1, anticorrosive composite is free of in sample 1, therefore fungistatic effect is worst；Sample 2, sample 3 and sample 4 add
Enter antiseptic composition, all shows preferable bactericidal and bacteriostatic effect.By comparing discovery, active components of plants is added
Sample of the sample 2 than adding butanediol and pentanediol of long and thin hot pepper berry extract, pasque flower extract, palpus extractive of usnea
3 fungistatic effects are more notable；And add long and thin hot pepper berry extract, pasque flower extract, must extractive of usnea, butanediol and
4 fungistatic effect of sample of pentanediol is best, illustrates butanediol, the addition of pentanediol has collaboration fungistatic effect, makes the plant of composition
Active constituent compounds butanediol and the plant antiseptic agent composition fungistatic effect of pentanediol reaches best.
Embodiment seven
Facial mask nti-freckle is tested
1, object select：Choose 25~40 years old age, face has the women of the pigments such as different degrees of chloasma, butterfly macules
200, wherein 25~30 years old 100,30~35 years old 50,35~40 years old 50.
2, film sample：Using the sample 1 and the sample tested as this facial mask nti-freckle of sample 4 in embodiment six.
3, experimental method：Before sleep every night after cleaning skin, the facial mask of 5g or so is uniformly applied on the face, is kept
20 minutes, facial mask formed a film at this time, threw off the facial mask of film forming, cleans residual liquor with clear water, is used continuously 6 months.
4, curative effect determinate standard：It is almost recovered：Naked eyes disappear substantially depending on color spot；It is effective：Naked eyes regard color spot subside 60% with
On；Effectively：Naked eyes regard 20% or more color spot recession；In vain：Naked eyes regard 20% or less color spot recession.
Cure rate=recovery from illness number/total number of cases
Efficient=(recovery from illness number of cases+effective number of cases+effective number of cases)/total number of cases
5, therapeutic effect is shown in Table 2
2 freckle-removing mask using effect statistical form of table
As can be seen from Table 2, sample 1 and sample 4 all have preferable freckle effect to the women of 25~40 age brackets, have
Efficiency reaches 84% or more.The age freckle-removing mask effect of the women application present invention between 25~30 years old is best, cures
Rate and effective percentage are above women of the age between 30~40 years old.Contrast sample 1 and sample 4, discovery contain plant antiseptic agent
The facial mask freckle effect of composition is more preferable, this may be due to its in certain ingredients and the facial mask in plant antiseptic agent composition
The coefficient result of his ingredient.
The above is only presently preferred embodiments of the present invention, is not intended to limit the present invention in any form, it is every according to
According to the technical spirit of the present invention to any simple modification, equivalent variations made by above example, the protection of the present invention is each fallen within
Within the scope of.
Claims (5)
1. a kind of freckle-removing mask, which is characterized in that containing plant antiseptic agent composition, the plant antiseptic agent composition is by plant
Active constituent has been equipped with the butanediol of collaboration bacteriostasis and pentanediol is composed, and the active components of plants includes prickly ash berries
Extract, pasque flower extract, palpus extractive of usnea, the long and thin hot pepper berry extract, pasque flower extract, palpus sunglo
The weight proportion of extract is 2：1~3：1~3；With the total weight of facial mask, weight of the active components of plants in facial mask
Percentage is 0.03~3%, and weight percent of the butanediol in facial mask is 5~10%, quality hundred of the pentanediol in facial mask
Divide than being 3~5%；
The long and thin hot pepper berry extract is prepared as follows：According to the ratio of every gram of prickly ash berries 25mL Extraction solvent, washing
Only a concentration of 80% ethyl alcohol Extraction solvent is added in the prickly ash berries after drying, 80~85 ° keep the temperature 1~2h of refluxing extraction, cool down,
Centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The pasque flower extract is prepared as follows：According to the ratio of every gram of pasque flower 25mL Extraction solvent
A concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extractions are added in example in cleaning the pasque flower after drying
1~2h, cooling, centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The palpus extractive of usnea is prepared as follows：According to the ratio of every gram of palpus sunglo 25mL Extraction solvent, cleaning
Be added a concentration of 80% ethyl alcohol Extraction solvent in palpus sunglo after drying, 80~85 ° of heat preservation 1~2h of refluxing extraction, it is cooling, from
The heart, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The other components and weight percentage of the facial mask are as follows：
Polyvinyl alcohol crosslinked polymer 10~15%
Ethyl alcohol 3~5%
Papain 0.6~1%
Donkey-hide gelatin 4~10%
Ginseng root extract 0.5~0.8%
Leonurus extract 5~8%
Licorice root extract 5~8%
Kuh-seng root extract 5~8%
Ginkgo biloba p.e 0.5~5%
Baical Skullcap root P.E 2~5%
Stephania tetrandra extract 0.1~1%
Carbomer 0.05~0.2%
Remaining is deionized water.
2. freckle-removing mask according to claim 1, which is characterized in that the pH value of the freckle-removing mask with 10% hydroxide
Potassium solution is adjusted to 5~6.
3. freckle-removing mask according to claim 1, which is characterized in that the ginseng root extract, Leonurus extract, sweet
Grass roots extract, kuh-seng root extract, ginkgo biloba p.e, Baical Skullcap root P.E raw material respectively with 80% ethyl alcohol heat preservation reflux carry
1~2h, centrifugation, filtering, filtered extracting solution is taken to be concentrated under reduced pressure into 5 times of concentration and obtain extract.
4. a method of preparing freckle-removing mask as described in claim 1, which is characterized in that include the following steps：
(1) polyvinyl alcohol crosslinked polymer is added in deionized water, is heated to 80 ° of dissolvings；
(2) above-mentioned temperature is kept, carbomer is slowly added into (1) while stirring, until carbomer complete swelling, is well dispersed in
(1) in；
(3) pH to 5~6 is adjusted with 10% potassium hydroxide solution, starts to cool down, when temperature is down to 40 °, (2) are added in ethyl alcohol
Middle stirring then adds donkey-hide gelatin, ginseng root extract, Leonurus extract, licorice root extract, kuh-seng root extract, silver
Apricot leaf extract, Baical Skullcap root P.E, stephania tetrandra extract, the plant antiseptic agent composition stir evenly up to facial mask liquid.
5. a kind of method for the freckle effect improving freckle-removing mask, is included in addition plant antiseptic agent composition in freckle-removing mask,
The wherein described freckle-removing mask contains polyvinyl alcohol crosslinked polymer 12%, ethyl alcohol 3%, papain 1%, donkey-hide gelatin 10%, people
Join root extract 0.8%, Leonurus extract 5%, licorice root extract 5%, kuh-seng root extract 6%, ginkgo biloba p.e
3%, Baical Skullcap root P.E 4%, stephania tetrandra extract 0.8%, carbomer 0.1%；With the total weight of facial mask, the antiseptic
Agent composition contains long and thin hot pepper berry extract 1%, pasque flower extract 1%, palpus extractive of usnea 1%；Butanediol 6%, penta
Glycol 4%；
The long and thin hot pepper berry extract is prepared as follows：According to the ratio of every gram of prickly ash berries 25mL Extraction solvent, washing
Only a concentration of 80% ethyl alcohol Extraction solvent is added in the prickly ash berries after drying, 80~85 ° keep the temperature 1~2h of refluxing extraction, cool down,
Centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The pasque flower extract is prepared as follows：According to the ratio of every gram of pasque flower 25mL Extraction solvent
A concentration of 80% ethyl alcohol Extraction solvent, 80~85 ° of heat preservation refluxing extractions are added in example in cleaning the pasque flower after drying
1~2h, cooling, centrifugation, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves；
The palpus extractive of usnea is prepared as follows：According to the ratio of every gram of palpus sunglo 25mL Extraction solvent, cleaning
Be added a concentration of 80% ethyl alcohol Extraction solvent in palpus sunglo after drying, 80~85 ° of heat preservation 1~2h of refluxing extraction, it is cooling, from
The heart, filtering, filtered extracting solution are concentrated under reduced pressure, and freeze-drying preserves.
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| KR101708156B1 (en) * | 2016-09-30 | 2017-02-17 | 주식회사 유로프 | Bio cellulose sheet, articles for bio cellulose sheet, and manufacturing methods thereof |
| CN107536746A (en) * | 2017-07-19 | 2018-01-05 | 广州市馨雨化妆品有限公司 | A kind of plant extract composition with antisepsis and its preparation method and application |
| CN107308064A (en) * | 2017-08-08 | 2017-11-03 | 广州蜜妆生物科技有限公司 | A kind of compound natural preservative |
| CN107854349A (en) * | 2017-09-19 | 2018-03-30 | 丰小为 | One kind reduction elite and its processing technology |
| CN108066266A (en) * | 2017-12-20 | 2018-05-25 | 钱小平 | A kind of facial mask with skin makeup function |
| CN109793680B (en) * | 2018-12-25 | 2022-04-19 | 深圳市唯可依日用品有限公司 | Skin-care composite fruit and plant anti-allergy extracting solution and preparation method and application thereof |
| CN109646324A (en) * | 2019-02-25 | 2019-04-19 | 高源� | The compact whitening spot-relieving cream and preparation method thereof that collagen composite plant extracts |
| CN109998970A (en) * | 2019-04-30 | 2019-07-12 | 广州方媚化妆品有限公司 | The compact maintenance stoste of plant quintessence |
| CN110151660B (en) * | 2019-07-08 | 2022-07-12 | 北京书路一品文化发展有限公司 | Eye care gel and preparation method thereof |
| CN110279599B (en) * | 2019-07-10 | 2022-04-01 | 中山卡丝生物科技有限公司 | Whitening composition, set containing whitening composition and preparation method of set |
| CN111888307A (en) * | 2020-07-17 | 2020-11-06 | 重庆珂蓝健康管理集团有限公司 | Composition for repairing and healing face and application thereof |
| CN115487125B (en) * | 2022-01-28 | 2023-09-12 | 山西海博贝马生物科技有限公司 | Sterilization composition and application thereof |
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| CN103535385A (en) * | 2013-10-25 | 2014-01-29 | 北京桑普生物化学技术有限公司 | Plant extract and synergist contained antimicrobial composition |
| CN104825381A (en) * | 2015-05-18 | 2015-08-12 | 中山安理汇日用品有限公司 | Essence with self-preservative characteristic |
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| CN103535385A (en) * | 2013-10-25 | 2014-01-29 | 北京桑普生物化学技术有限公司 | Plant extract and synergist contained antimicrobial composition |
| CN105687005A (en) * | 2014-11-26 | 2016-06-22 | 天津科丝美特生物科技有限公司 | Spot-fading whitening skin care composition |
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