CN105918325A - Pesticide granule containing probenazole and metalaxyl-M - Google Patents

Pesticide granule containing probenazole and metalaxyl-M Download PDF

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Publication number
CN105918325A
CN105918325A CN201610279128.5A CN201610279128A CN105918325A CN 105918325 A CN105918325 A CN 105918325A CN 201610279128 A CN201610279128 A CN 201610279128A CN 105918325 A CN105918325 A CN 105918325A
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Prior art keywords
metalaxyl
probenazole
pesticide granule
pesticide
weight
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CN201610279128.5A
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Chinese (zh)
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CN105918325B (en
Inventor
吴宝国
梁佳韬
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Shandong Aosheng Biotechnology Co ltd
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Guangxi Nanning Yitu Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12Powders or granules
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46N-acyl derivatives

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a pesticide granule containing probenazole and metalaxyl-M. The pesticide granule is composed of the following effective components by weight: 5 to 10% of probenazole and 0.5 to 3.0% of metalaxyl-M, wherein a weight ratio of probenazole to metalaxyl-M is (10-20): (1-5). The pesticide granule provided by the invention is used for prevention and treatment of rice seedling blight in a dry rice seedling period, has significant formula synergism and good systemic properties, can effectively control diseases and pests, and has the effects of saving time, labor and efforts.

Description

A kind of containing probenazole with the granular pesticide of Metalaxyl-M
Technical field
The present invention relates to technical field of pesticide, be specifically related to a kind of containing probenazole with the granular pesticide of Metalaxyl-M.
Background technology
Probenazole, English general entitled: probenazole, it is the one of Meiji Seika Kaisha, Ltd. of Japan exploitation Inducing immunity antibacterial, realizes protection effect, by planting by exciting plant itself to react the immunity (resistance) of disease Thing root absorption, and relatively rapidly infiltration is conducted to plant each several part.Probenazole processes Oryza sativa L., can promote Root Absorption, And relatively rapidly infiltration conduction is to plant each several part, cover crop is not infected by Pyricularia oryzae and rhizoctonia solani..
Metalaxyl-M, English general entitled: metalaxyl-M, it is a kind of efficiently systemic fungicide, protected and therapeutical effect, Drug effect is high, it is low to remain, to Pseudoperonospora cubensis, and phytophthora pathogenic bacteria, the vegetable caused by rotten mildew fungus, fruit tree, Nicotiana tabacum L., oil plant, Cotton Gossypii, The crop pests such as grain have efficiently.
Present stage, raising rice seedlings realizes the transformation from watery ricenursery to dry rice seedling substantially, and rice shoot disease be still watered with medicament spray into Row preventing and treating, relatively time-consuming arduously.In the case of rural labour's shortage, the method for effort-saving prevention and elimination of disease and pests is more and more concerned, The present invention is compounded by effective ingredient probenazole and Metalaxyl-M, makes granular pesticide, and its Uptake and translocation is good, in seedling During operation or seeding stage is used, can effectively prevent and treat rice seedling damping-off, reach the effect of time and labour saving.
At present, probenazole be there are no relevant report to the research of Metalaxyl-M mixture.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of containing probenazole with the granular pesticide of Metalaxyl-M, for drought The preventing and treating of seedling phase rice damping-off, its formula potentiation is notable, and interior absorption is good, can effectively control disease, have time and labour saving laborsaving Effect.
The present invention adopts the technical scheme that: a kind of containing probenazole with the granular pesticide of Metalaxyl-M, effective ingredient allyl Benzene thiazole and Metalaxyl-M composition, wherein the weight ratio of probenazole and Metalaxyl-M is: 10-20:1-5, it is preferred that allyl The weight ratio of benzene thiazole and Metalaxyl-M is 15:2.
Described probenazole percentage by weight in granular pesticide is 5-10%, and Metalaxyl-M is in granular pesticide Percentage by weight is 0.5-3.0%.
The adjuvant that the granular pesticide of the present invention adds includes filler, binding agent, dispersant, wetting agent, disintegrating agent, stablizes Agent or other be of value to the material that effective ingredient is stable in the formulation and drug effect plays, be all conventional in field of pesticide preparation or permission The various compositions used.
The present invention has the following advantages and significant technique effect:
(1) probenazole and Metalaxyl-M have double action mechanism, and mutual mixture pathogenic bacteria is not likely to produce resistance.
(2) indoor biometrics result shows, probenazole and Metalaxyl-M are compounding obvious to rhizoctonia solani potentiation according to a certain percentage, Applications of pesticide amount can be reduced and reduce pesticide cost.
(3) present invention is prepared as granular pesticide, uses in conjunction with during dry rice seedling operation or during seedling, alleviates farming operation, more Add and save labor.
Detailed description of the invention
Being described further technical scheme and beneficial effect below in conjunction with embodiment, percentage ratio of the present invention is equal It is weight percentage.
One, preparation embodiment
Embodiment 1:5.5% probenazole Metalaxyl-M granule (effective ingredient is than 10:1)
Formula: weigh probenazole 5%, Metalaxyl-M 0.5%, naphthalenesulfonate formaldehyde condensation compound 4%, dodecyl by weight Sodium sulfate 3%, polyvinyl alcohol 3.5%, bentonite complements to 100%.
Embodiment 2:8.5% probenazole Metalaxyl-M granule (effective ingredient is than 15:2)
Formula: weigh probenazole 7.5%, Metalaxyl-M 1%, naphthalenesulfonate formaldehyde condensation compound 3%, dodecyl by weight Sodium sulfate 3.5%, polyvinyl alcohol 3%, attapulgite 12%, Kaolin complements to 100%.
Embodiment 3:12.5% probenazole Metalaxyl-M granule (effective ingredient is than 20:5)
Formula: weighing probenazole 10%, Metalaxyl-M 2.5%, sodium lauryl sulphate 2.5% by weight, carboxymethyl is fine Dimension element 3.5%, kieselguhr 15%, bentonite complements to 100%.
Embodiment 4:13% probenazole Metalaxyl-M granule (effective ingredient is than 10:3)
Formula: weigh probenazole 10%, Metalaxyl-M 3%, naphthalenesulfonate formaldehyde condensation compound 5%, dodecyl sulfur by weight Acid sodium 2.5%, polyvinyl alcohol 5%, Kaolin complements to 100%.
Preparation method: by the recipe ingredient mix homogeneously described in above-described embodiment 1-4, pulverizes, stirs after adding water-wet, Use screw extruder pelletizer pelletize again, sieve after drying and i.e. obtain containing probenazole Metalaxyl-M granule.
Two, BIOLOGICAL ACTIVITY EXAMPLES
The BIOLOGICAL ACTIVITY EXAMPLES of the present invention is the method using Toxicity Determination and field test to combine.
Embodiment 1: probenazole, Metalaxyl-M and the built agent Toxicity Determination to rice seedling blight
After prerun determines each medicament effective inhibition concentration scope, by probenazole, Metalaxyl-M and mixed agent thereof by effectively becoming Divide 5 concentration of concentration gradients serial dilution, if clear water comparison.Enter with reference to " farm-chemical indoor determination test rule antibacterial " OK, mycelial growth rate method is used to measure the medicament virulence to rhizoctonia solani.Colony diameter is measured by decussation method after 72h, Calculate each process net growth, mycelial growth inhibition rate.
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) is converted into logarithm value (x), with Little square law tries to achieve virulence regression equation (y=a+bx), and thus calculates the EC of every kind of medicament50Value.
It is antagonism that co-toxicity coefficient method (CTC) according to the abundant method of Sun Yun evaluates the potentiation of pharmacy mix, i.e. CTC≤80 Effect, 80<CTC<120 is summation action, and CTC>=120 are potentiation.Statistical result is as shown in table 1:
Reagent agent Proportioning EC50(mg/L) Co-toxicity coefficient (CTC)
Probenazole (A) / 1.51 /
Metalaxyl-M (B) / 2.57 /
A:B 10:1 1.23 127.6
A:B 10:3 1.26 132.1
A:B 10:5 1.22 142.8
A:B 15:1 1.16 133.4
A:B 15:2 0.95 166.9
A:B 15:5 1.25 134.6
A:B 20:1 1.16 132.6
A:B 20:3 1.27 125.8
A:B 20:5 1.25 131.6
A:B 1:9 3.05 78.6
Measurement result shows, when the proportioning of probenazole and Metalaxyl-M is 10-20:1-5, co-toxicity coefficient (CTC) is more than 120, potentiation is obvious.
Embodiment 2: the preparation of preparation embodiment 2 gained is for preventing and treating the field control effectiveness test of rice seedling blight
(1) EXPERIMENTAL DESIGN: as test group 1#, amount of application be using 8.5% probenazole Metalaxyl-M (15:2) granule 0.1 kilogram/m2;With 8% probenazole granule for matched group 1#, amount of application is 0.15 kilogram/m2;With 12% Metalaxyl-M Granule is matched group 2#, and amount of application is 0.15 kilogram/m2, 1 blank group is set.
(2) application method
Select anosis seedling plot, smooth seedling furrow, by uniform for the mixing with soil with rhizoctonia solani, be layered on successively and will test On seedling furrow, it is desired to the thickness of soil in spite of illness on furrow is consistent.The seed-grain having urged bud is planted in soil, each process 3 in test Secondary repetition, plot area 1m2, by EXPERIMENTAL DESIGN by test group 1#, matched group 1#, matched group 2# corresponding medicament by regulation use Amount uniformly imposes on the community of correspondence, keeps seedbed environment consistent in each community.
(3) result of the test
After medicine 10 days, investigating in conjunction with rice shoot damping-off high-incidence season result, calculate sickness rate and prevention effect, result shows, test group 1# is 91.53% to the prevention effect of rice shoot damping-off, and matched group 1# is 71.24% to the prevention effect of rice shoot damping-off;Matched group 2# is 74.52% to the prevention effect of rice shoot damping-off.Find out from test, after probenazole and Metalaxyl-M mixture, mixture Agent is obvious to rice shoot damping-off potentiation, had both reduced the usage amount of effective ingredient, and had shown again the field efficacy being better than single dose, have Help reduce Pesticide use cost.

Claims (4)

1. one kind contains probenazole and the granular pesticide of Metalaxyl-M, it is characterised in that probenazole and Metalaxyl-M Weight ratio is: 10-20:1-5.
The most according to claim 1 containing probenazole with the granular pesticide of Metalaxyl-M, it is characterised in that phenyl allyloxy The weight ratio of thiazole and Metalaxyl-M is 15:2.
The most according to claim 1 and 2 containing probenazole with the granular pesticide of Metalaxyl-M, it is characterised in that alkene The percentage by weight of propyl benzene thiazole is 5-10%, and the percentage by weight of Metalaxyl-M is 0.5-3%.
4. according to described in claims 1 to 3 containing probenazole and the granular pesticide of Metalaxyl-M, it is characterised in that institute The granular pesticide stated is applicable to prevent and treat the rice damping-off of dry rice seedling.
CN201610279128.5A 2016-04-28 2016-04-28 A kind of granular pesticide containing probenazole and Metalaxyl-M Active CN105918325B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108013077A (en) * 2018-01-17 2018-05-11 河南科技学院 A kind of microbe soil fungicide

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629428A (en) * 1967-09-07 1971-12-21 Meiji Seika Kaisha Pesticide for controlling bacterial and fungal diseases of rice plant
US4855311A (en) * 1987-04-24 1989-08-08 Agro-Kanesho Co., Ltd. Benzoisothiazole oximes which are plant protection agents for control of fungi and bacteria
CN103238622A (en) * 2012-02-10 2013-08-14 陕西美邦农药有限公司 Bactericidal composition containing probenazole

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629428A (en) * 1967-09-07 1971-12-21 Meiji Seika Kaisha Pesticide for controlling bacterial and fungal diseases of rice plant
US4855311A (en) * 1987-04-24 1989-08-08 Agro-Kanesho Co., Ltd. Benzoisothiazole oximes which are plant protection agents for control of fungi and bacteria
CN103238622A (en) * 2012-02-10 2013-08-14 陕西美邦农药有限公司 Bactericidal composition containing probenazole

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张一宾,徐进: "作物抗病激活剂烯丙苯噻唑的合成", 《现代农药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108013077A (en) * 2018-01-17 2018-05-11 河南科技学院 A kind of microbe soil fungicide

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Effective date of registration: 20181206

Address after: 448200 Guodian Village, Jishan Town, Shayang County, Jingmen City, Hubei Province

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Address before: 530000 room 3106, block C, hang Yang International City, No. 131, National Road, Qingxiu District, Nanning, the Guangxi Zhuang Autonomous Region.

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