CN105902700B - A kind of composite essential oil and preparation method thereof for alleviating post-exercise muscle soreness - Google Patents
A kind of composite essential oil and preparation method thereof for alleviating post-exercise muscle soreness Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention discloses a kind of composite essential oils for alleviating post-exercise muscle soreness, including following parts by weight composition: 60~97 parts of grape pip essential oil, 0.1~10 part of Rosemary Oil, 0.1~10 part of lemon, 0.1~10 part of clary sage essential oil, 0.1~10 part of Basil Essential.Composite essential oil prepared by the present invention has no irritating odor, and DOMS sense can be effectively relieved after smearing, while reducing serum creatine kinase level, reduces because of DOMS symptom caused by muscle after exercise micro-damage.
Description
Technical field
The present invention relates to a kind of essential oil, more particularly to a kind of composite essential oil for alleviating post-exercise muscle soreness.
Background technique
Essential oil is in the flower from plant, leaf, stem, root or fruit, passes through steam distillation, extrusion, cold-maceration or molten
Agent extraction method refines the volatile flavor of extraction.Essential oil divides diluted (compound essential oil) and not diluted (folk prescription essence again
Oil).The volatility of essential oil is very strong, once ingress of air will volatilize quickly, also based on this reason, essential oil must be used can be close
The dark-colored bottle of envelope stores, once corkage uses, also to cover back lid as early as possible.
In the prior art, essential oil has the smell for making one to feel comfortable, and is mainly used to play the role of antitoxic heart-soothing and sedative.It is passed through in people
After crossing movement, bring is ached sense after alleviating movement using essential oil, but this alleviate is not obvious.Also, existing skill
Often smeared using Chinese materia medica preparation in art, after movement ache place relieve the soreness sense, but Chinese materia medica preparation often have it is strong
Penetrating odor, sense of discomfort can be brought to people, especially in public using the discomfort that will also result in other staff.
Summary of the invention
In view of the deficiencies of the prior art, the present invention intends to provide while one kind has no irritating odor to have
Preferably alleviate the composite essential oil of post-exercise muscle soreness.
To achieve the above object, the present invention provides the following technical scheme that
A kind of composite essential oil for alleviating post-exercise muscle soreness, including following parts by weight composition:
As a further improvement of the present invention:
It is formed including following parts by weight:
As a further improvement of the present invention:
It is formed including following parts by weight:
As a further improvement of the present invention:
Further include following parts by weight composition:
0.1~5 part of sweet almond seed oil
0.1~5 part of methyl trioleate
As a further improvement of the present invention:
Further include following parts by weight composition:
0.1~5 part of hydroxypropyl methyl cellulose tristearin oxygen ether
0.1~5 part of dihydroxypropyl arginine.
As a further improvement of the present invention:
Further include following parts by weight composition:
0.1~5 part of tea polyphenols
0.1~5 part of peppermint oil
0.1~5 part of trehalose.
A kind of preparation method of composite essential oil that alleviating post-exercise muscle soreness
Step 1: by part grape pip essential oil and hydroxypropyl methyl cellulose tristearin oxygen ether, dihydroxypropyl arginine into
Row mixing, obtains defoaming component；
Step 2: by remaining grape pip essential oil and Rosemary Oil, lemon, clary sage essential oil, Basil Essential
And the defoaming component in step 1 is stirred mixing, stirring rate 200r/min, mixing time is 5~20 minutes；
Step 3: sweet almond seed oil, methyl trioleate, peppermint oil are added to the mixing that step 2 obtains simultaneously
In object, it is stirred mixing, stirring rate 200r/min, mixing time is 5~10 minutes, obtains the thick finished product of composite essential oil；
Step 4: tea polyphenols, trehalose are mixed with ethyl alcohol, being heated to 28~30 degrees Celsius later makes ethyl alcohol volatilize
10~20 minutes, obtain function additive；
Step 5: the thick finished product of composite essential oil in step 3 and the function additive in step 4 are stirred mixing, stirred
Mixing rate is 150~200r/min, stirring 5~after twenty minutes, and it stands and obtains composite essential oil in 10~30 minutes.
In formula of the invention, grape pip essential oil is refined by grape seed via five-star cold pressing mode；Fan
Repeatedly essential oil is a kind of colourless to faint yellow volatile liquid, and rosemary stem is about 1 meter high, and leaf is linear, is about 1 centimeter, shape
Like curved pine needle, bottle green, above it is bright, below white, leaf margin crimps to blade back, distills from rosemary by blade water
Extraction；It is the main chemical compositions sobrerone or firpene of lemon, amphene, sabinene, laurel (spiceleaf) alkene, dipentene, linalool, red
Heerabolene, limonene, nerol and neral, extracted in lemon from；Clary sage essential oil, by Salvia japonica distillation
Come, Salvia japonica, English name: CLARY SAGE, draft small shrub plant, leaf is very special, is pale purple green, Hua Weilan
Color, belongs to draft shrub type, and averagely 50~70 centimeters of height, the main place of production is the Balkan Peninsula, essential oil distillation from its leaf with
Flower is in chartreuse, the fragrance with some sweet tastes and fennel, camphor；Basil Essential also known as Fructus Perillae quintessence oil, Basil Essential are exactly
It is called in the plant of aniseed obtained by extraction from a kind of.
In entire composite essential oil system, using grape pip essential oil as carrier, by Rosemary Oil, lemon, happy mouse
Tail grass essential oil, Basil Essential are mixed.Grape pip essential oil all has preferable compatibility to most grease substance, simultaneously
Property is soft, also has the function of preferably protecting skin, therefore very practical with as carrier, is applied on human skin not only
Skin will not be damaged, one preferable protecting effect of skin can be also given.Rosemary Oil itself has the fragrance of calm nerves, energy
It is enough enable people obtained in DOMS one it is spiritual releive, to slow down sense of aching.Meanwhile Rosemary Oil has
There is very strong inoxidizability, and the free radical of muscle after exercise generation can be alleviated, DOMS caused by thus protection moves.
And the addition of lemon, the fragrance with a kind of lemon itself can promote the generation of lactic acid while playing calm nerves
Thank, and fight because lactic acid excessively caused by DOMS, with Rosemary Oil generate synergy, under human body relaxation state,
More be conducive to the recovery from illness of DOMS.The smell of clary sage essential oil is happy and motivates the nut taste of people's spirit, heavy feeling compared with
By force, body immunity can be promoted to enhance, further enhances the alleviation of DOMS.Basil Essential has improvement functional disturbance
Effect can stimulate human body, so that DOMS is eased.A synergy can be played by compounding, is further delayed
Solution muscle is ached, while can also accelerate the metabolism of body lactic acid, is reduced muscle micro-damage and is enabled to restore after exercise more
Fastly.
Sweet almond seed oil is added, the effect for protecting skin not stimulated can be further functioned as, sweet almond seed oil is interior also
Vitamin abundant, one can be played to wound healing by playing the role of wound in time also.In addition sweet almond seed oil can be to multiple
The oil substances closed in essential oil play a protective role, and prevent it from causing quality to change during long-time is stored.
Methyl glucoside trioleate is added in whole system as expanding material, so that each component is dispersed in system
Can be more preferable, so that the effect of entire composite essential oil is more uniform.
Hydroxypropyl methyl cellulose tristearin oxygen ether, dihydroxypropyl arginine are added to entirely as thickener and defoaming agent
It is good defoaming agent since hydroxypropyl methyl cellulose tristearin oxygen ether and dihydroxypropyl arginine have hydroxyl in system,
The viscosity of whole system can be also adjusted simultaneously.The effect for improving whole weatherability can more importantly be played.Guarantee will not
Qualitative change occurs.
Tea polyphenols, peppermint oil, trehalose are added in system, tea polyphenols have preferable antibacterial effect, and whole system is all
Plants essential oil, it is easy to bacteria breed can be prevented by the addition of microbial attack, tea polyphenols, so there is no need to additionally add
Antibacterial agent.Peppermint oil can have a preferable refrigerant sense after smearing human skin, and the muscle ached is enabled to be delayed
Solution.Trehalose has a preferable protective ingredient for plants essential oil, can be improved the weatherability of whole system.
Specific embodiment
Embodiment one
Embodiment two
Embodiment three
Example IV
Embodiment five
Comparative example one
100 parts of of grape pip essential oil
Comparative example two
97 parts of grape pip essential oil
2 parts of Rosemary Oil
Comparative example three
97 parts of grape pip essential oil
0.25 part of lemon
Comparative example four
97 parts of grape pip essential oil
0.25 part of clary sage essential oil.
Comparative example five
97 parts of grape pip essential oil
0.25 part of Basil Essential.
After people carried out strenuous exercise, oneself DOMS is often found.A part is just to move later i.e.
Quarter performance is unobvious, and degree of often aching after 24-48h after exercise reaches peak value, gradually mitigates after 72h, general 7 days left sides
The right side substantially eliminates.Caused by this is in fact two aspect reasons, both DOMSs are divided into the following two kinds in modern medicine:
It is acute to ache:
Pain occurs during exercise or in the one extremely short time after movement just for muscle.It is acute to ache and act on
The interruption that blood flow is formed when flesh is exerted oneself is related, remove metabolite can not, and is deposited in muscle,
And then it stimulates and arrives pain sensation receptor.
It is chronic to ache:
Between the muscle chronic 24-48 hour after being frequently experienced in training of aching.The chronic degree ached of muscle and muscle
The form of contraction is related, and centrifugation contraction, which is easiest to form the chronic of muscle, aches, and isotonic contraction is least significant.Muscle has chronic acid
When the situation of pain occurs, muscular strength is decreased obviously.
By the detection to the intracorporal blood of people, it is acute ache when, muscle cell discovery is exhaled mainly in motion process
Suction effect, generates a large amount of lactic acid, thus caused by ache, generally after movement stops in several hours, lactic acid content in blood
It will be greatly reduced, can be used to measure the acute main indicator ached.
In addition, after exercise, since muscle has different degrees of muscle micro-damage, a large amount of creatine kinase can be generated,
For repairing the damage of muscle, while the generation of creatine kinase, is accumulated on muscle cell, generate sense of aching, this is also chronic
The main reason for aching, therefore creatine kinase can be used to measure muscle damage degree and recovery extent.
Test method: blood lactase acid value university student after the movement of 7~8mmol/L after being trained with resistive exercise+explosive force, with
5 people are one group, and (time point is respectively after moving to detection blood lactase acid level after the formula essential oil of smearing comparative example and embodiment
Can, 5min, 30min, 1h, 2h, 4h), the evaluation of the sense that then carries out aching (it is stiff to be divided into DOMS evaluation, tenderness evaluation, joint
Hardness evaluation, each evaluation basis never feel that extreme pain is divided into 1-10 points), the time for evaluation of aching is respectively to move
Afterwards at once, 1 day after movement, 2 days after movement, 3 days after movement, 7 days after movement, comparative example and Example formulations are smeared in 7 days
Essential oil；Simultaneously serum creatine kinase (CK) level is detected respectively within 1 day after 2h and movement after experiment.
In addition the composite essential oil respectively prepared comparative example and embodiment, after being placed on test in hernia light irradiation 100 hours
Post-exercise muscle soreness personnel are smeared, detection blood lactase acid level, the evaluation for sense of aching, serum creatine kinase (CK) are horizontal.
Smearing mode are as follows: take 20ml composite essential oil, be applied to whole leg.
Table one: DOMS evaluation when without hernia light irradiation
Table two: muscle palpation when without hernia light irradiation is ached evaluation
Table three: creatine kinase evaluation when without hernia light irradiation
Table four: blood lactase acid evaluation when without hernia light irradiation
Table five: the DOMS evaluation after hernia light irradiation 100 hours
Table six: the muscle palpation after hernia light irradiation 100 hours is ached evaluation
Table seven: the creatine kinase evaluation after hernia light irradiation 100 hours
Table eight: the blood lactase acid evaluation after hernia light irradiation 100 hours
In entire composite essential oil system, using grape pip essential oil as carrier, by Rosemary Oil, lemon, happy mouse
Tail grass essential oil, Basil Essential are mixed.Grape pip essential oil all has preferable compatibility to most grease substance, simultaneously
Property is soft, also has the function of preferably protecting skin, therefore very practical with as carrier, is applied on human skin not only
Skin will not be damaged, one preferable protecting effect of skin can be also given.Rosemary Oil itself has the fragrance of calm nerves, energy
It is enough enable people obtained in DOMS one it is spiritual releive, to slow down sense of aching.Meanwhile Rosemary Oil has
There is very strong inoxidizability, and the free radical of muscle after exercise generation can be alleviated, DOMS caused by thus protection moves.
And the addition of lemon, the fragrance with a kind of lemon itself can promote the generation of lactic acid while playing calm nerves
Thank, and fight because lactic acid excessively caused by DOMS, with Rosemary Oil generate synergy, under human body relaxation state,
More be conducive to the recovery from illness of DOMS.The smell of clary sage essential oil is happy and motivates the nut taste of people's spirit, heavy feeling compared with
By force, body immunity can be promoted to enhance, further enhances the alleviation of DOMS.Basil Essential has improvement functional disturbance
Effect can stimulate human body, so that DOMS is eased.A synergy can be played by compounding, is further delayed
Solution muscle is ached, while can also accelerate the metabolism of body lactic acid, is reduced muscle micro-damage and is enabled to restore after exercise more
Fastly.
Sweet almond seed oil is added, the effect for protecting skin not stimulated can be further functioned as, sweet almond seed oil is interior also
Vitamin abundant, one can be played to wound healing by playing the role of wound in time also.In addition sweet almond seed oil can be to multiple
The oil substances closed in essential oil play a protective role, and prevent it from causing quality to change during long-time is stored.
Methyl glucoside trioleate is added in whole system as expanding material, so that each component is dispersed in system
Can be more preferable, so that the effect of entire composite essential oil is more uniform.
Hydroxypropyl methyl cellulose tristearin oxygen ether, dihydroxypropyl arginine are added to entirely as thickener and defoaming agent
It is good defoaming agent since hydroxypropyl methyl cellulose tristearin oxygen ether and dihydroxypropyl arginine have hydroxyl in system,
The viscosity of whole system can be also adjusted simultaneously.The effect for improving whole weatherability can more importantly be played.Guarantee will not
Qualitative change occurs.
Tea polyphenols, peppermint oil, trehalose are added in system, tea polyphenols have preferable antibacterial effect, and whole system is all
Plants essential oil, it is easy to bacteria breed can be prevented by the addition of microbial attack, tea polyphenols, so there is no need to additionally add
Antibacterial agent.Peppermint oil can have a preferable refrigerant sense after smearing human skin, and the muscle ached is enabled to be delayed
Solution.Trehalose has a preferable protective ingredient for plants essential oil, can be improved the weatherability of whole system.
It can be concluded that, by composite essential oil prepared by inventive formulation, there is preferable alleviate by above-mentioned test data
DOMS sense, it is limited shorten it is entire restore the period, the metabolism and decomposition of lactic acid can be promoted, while from creatine kinase content
As can be seen that the restitution of musculature can be accelerated in variation.
Meanwhile be added to sweet almond seed oil, methyl trioleate, hydroxypropyl methyl cellulose tristearin oxygen ether,
The extended shelf-life that whole essential oil is enabled to after dihydroxypropyl arginine, tea polyphenols, peppermint oil, trehalose, it is resistance to improve its
Performance is waited, during long-time storage, appointing can so have the effect of preferably alleviating DOMS.
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation
Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art
Those of ordinary skill for, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications
It should be regarded as protection scope of the present invention.
Claims (2)
1. a kind of composite essential oil for alleviating post-exercise muscle soreness, it is characterised in that: formed including following parts by weight:
Further include following parts by weight composition:
0.1~5 part of sweet almond seed oil
0.1~5 part of methyl trioleate；
Further include following parts by weight composition:
0.1~5 part of hydroxypropyl methyl cellulose tristearin oxygen ether
0.1~5 part of dihydroxypropyl arginine；
Further include following parts by weight composition:
0.1~5 part of tea polyphenols
0.1~5 part of peppermint oil
0.1~5 part of trehalose.
2. the preparation method of composite essential oil as described in claim 1: it is characterized by:
Step 1: part grape pip essential oil and hydroxypropyl methyl cellulose tristearin oxygen ether, dihydroxypropyl arginine are mixed
It closes, obtains defoaming component；
Step 2: by remaining grape pip essential oil and Rosemary Oil, lemon, clary sage essential oil, Basil Essential and
Defoaming component in step 1 is stirred mixing, stirring rate 200r/min, and mixing time is 5~20 minutes；
Step 3: sweet almond seed oil, methyl trioleate, peppermint oil are added to the mixture that step 2 obtains simultaneously
In, it is stirred mixing, stirring rate 200r/min, mixing time is 5~10 minutes, obtains the thick finished product of composite essential oil；
Step 4: tea polyphenols, trehalose are mixed with ethyl alcohol, be heated to later 28~30 degrees Celsius make ethyl alcohol carry out volatilization 10~
20 minutes, obtain function additive；
Step 5: the thick finished product of composite essential oil in step 3 and the function additive in step 4 are stirred mixing, stirring speed
Rate is 150~200r/min, stirring 5~after twenty minutes, and it stands and obtains composite essential oil in 10~30 minutes.
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| CN107308407A (en) * | 2017-06-29 | 2017-11-03 | 芜湖凌梦电子商务有限公司 | A kind of effective composite essential oil for alleviating muscle cramp and joint pain |
| CN110169961B (en) * | 2019-06-12 | 2022-04-08 | 颇黎芳香医药科技（上海）有限公司 | Exercise rehabilitation compound essential oil |
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| CN1733152A (en) * | 2005-08-18 | 2006-02-15 | 谢作印 | Compound essence oil for curing arthralgia and myalgia of human |
| CN101199833A (en) * | 2007-12-21 | 2008-06-18 | 北京中科雍和医药技术有限公司 | Compound essential oil of releasing arthritis ache |
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| CN103386096A (en) * | 2012-05-11 | 2013-11-13 | 苏州纳特苏生物科技有限公司 | Compound essential oil for relieving neck and shoulder aches |
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| CN103285127A (en) * | 2013-05-22 | 2013-09-11 | 钟小强 | Composite essential oil for relieving muscle pain |
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| CN105062684A (en) * | 2015-08-31 | 2015-11-18 | 岭南师范学院 | Vetiver grass compound essential oil and preparation method thereof |
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