CN104027439B - Compositions and preparation method thereof - Google Patents

Compositions and preparation method thereof Download PDF

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CN104027439B
CN104027439B CN201310075301.6A CN201310075301A CN104027439B CN 104027439 B CN104027439 B CN 104027439B CN 201310075301 A CN201310075301 A CN 201310075301A CN 104027439 B CN104027439 B CN 104027439B
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oil
order
quintessence oil
mixture
compositions
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CN104027439A (en
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张思佳
黄璐
杨爽
朱江阳
汪小刚
张海峰
熊周权
康辉
汪建
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WUHAN HUADA GENE TECHNOLOGY CO LTD
WUHAN HUADA PHARMACEUTICAL CO Ltd
BGI Shenzhen Co Ltd
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WUHAN HUADA GENE TECHNOLOGY CO LTD
WUHAN HUADA PHARMACEUTICAL CO Ltd
BGI Shenzhen Co Ltd
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Abstract

The present invention relates to compositions, said composition includes: the Geranium Essential of 5 250 weight portions;The orange blossom quintessence oil of 2 100 weight portions;The Herba Lysimachiae foenum-graeci quintessence oil of 3 150 weight portions;The Inca inchi oil of 2 100 weight portions;And 8 400 Jojoba oil of weight portion.Said composition not only has improves microcirculation, pacifies neuralgic effect, moreover it is possible to significantly improve body immunity.

Description

Compositions and preparation method thereof
Technical field
The present invention relates to health product and cosmetic field.In particular to have improve microcirculation, pacify neuralgic Compositions and preparation method thereof.
Background technology
Directly participate in body substance, blood that energy transmits with information, lymph fluid, the flowing of tissue fluid are referred to as micro-following Ring, throughout each organ of whole body, its functional status and clinic are set one's heart, brain and peripheral blood vessel, diabetes, connective tissue disease etc. many Kind of disease wound, infect, the curative effect such as shock and judge in close relations the most afterwards, and improve microcirculation and all kinds of major diseases can be risen To the effect of prevention, after recovering, pathologic sequellae can be improved, nurse one's health body and mind, improve body immunity.And the most on the market Dragons and fishes jumbled together to improve microcirculatory medicine and health food, and curative effect is indefinite.
Neuropathic pain, has another name called neuropathic pain, is called for short neuralgia, is a kind of complexity and is difficult to the disease diagnosed Disease, is one of current clinical treatment facing challenges.In the U.S., the population of about 1.5% suffers neuralgic puzzlement, neural The Clinical symptoms of pain can be divided into spontaneous pain and Induced by Stimulation pain.Spontaneous pain can be described as acupuncture, calcination, Tear, cutting pains;Induced by Stimulation pain includes allodynia and hyperpathia.The neuralgic cause of disease is varied, bag Include the plyability neuropathy from physical injury to metabolic.Although the clinical symptoms of patient is similar, but its cause of disease and physiology Pathomechanism is the most different, and Drug therapy is to treat neuralgic main method at present, and clinical conventional medicine has anti- Epilepsy medicine, antidepressants, nmda antagonist, opium kind analgesics etc., wherein, antuepileptic and antidepressants are treatment neuralgias A line medication, and these medicines exist be only capable of relief of symptoms, various shortcoming that side effect is big, need to develop low toxicity, act on good Good natural drug fills a vacancy.
Plants essential oil is the secondary metabolites in plant.The simple compounds relatively small by molecular weight forms, tool There is certain aromatic odor, the oily liquids material that can volatilize at normal temperatures.Contained by plants essential oil, chemical composition is more complicated, by changing Learn structure can be divided into aliphatic, aromatic series and the big compounds of terpenoid 3 and their containing oxygen derivative such as alcohol, aldehyde, ketone, acid, Ether, ester, lactone etc., in addition with nitrogenous and sulfur-bearing compound.As the natural effective environmental protection composition extracted in plant, plant Quintessence oil, under the trend gone back to nature, has become as the physical therapy articles for use of contemporary society's fashion, and natural essential oil composition Popular, safety natural with it is undivided, and refines the fragrant ingredient of conventional food materials, is prepared as compositions, no matter external Or suck use, physical function can either be nursed one's health, reach to pacify neuralgia, improve microcirculatory effect, and have no side effect, Good effect.
Contemporary society is relatively big due to pressure, and the low crowd of microcirculation disturbance and neuralgia, body immunity is relatively wide, and shows Some medicine many employings chemical drugss, effect is notable not, and side effect is relatively big, there is certain room for improvement.Therefore Improve microcirculation at present, pacify neuralgic product and still have much room for improvement.
Summary of the invention
It is contemplated that solve one of above-mentioned technical problem the most to a certain extent or provide at a kind of useful business Industry selects.To this end, it is an object of the present invention to provide a kind of compositions, said composition has improves microcirculation, alleviation god The effect of dysmenorrhoea, and all components wide material sources in said composition, reasonable recipe, and without chemical addition agent, curative effect is true Cut.
In a first aspect of the present invention, the present invention proposes a kind of compositions, according to embodiments of the invention, said composition Including: Geranium Essential 5-250 part, orange blossom quintessence oil 2-100 part, Herba Lysimachiae foenum-graeci quintessence oil 3-150 part, Inca inchi oil 2-100 part, lotus lotus Bar oil 8-400 part.
Present inventor, through arduous creative work and Optimization Work, has surprisingly found that: by containing Flos Pelargonii Compositions prepared by quintessence oil, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil, has obvious Synergistic and makees With and technological progress feature, compositions of the present invention improving microcirculation, to pacify effect in terms of neuralgia obvious, and The action effect of compositions is substantially better than the effect of single component, has significant synergism.
According to embodiments of the invention, said composition preferably includes: Geranium Essential 60-180 part, orange blossom quintessence oil 20-80 Part, Herba Lysimachiae foenum-graeci quintessence oil 30-100 part, Inca inchi oil 20-80 part, Jojoba oil 100-220 part.Should thus, it is possible to improve further Compositions effect in terms of improving microcirculation and pacifying neuralgia.
According to embodiments of the invention, said composition most preferably includes: Geranium Essential 100 parts, orange blossom quintessence oil 40 parts, smoke Clothing grass quintessence oil 60 parts, Inca inchi oil 40 parts, Jojoba oil 160 parts.It is used for improving micro-thus, it is possible to improve further said composition Circulate and pacify the effect in terms of neuralgia.
The perennial undershrub of Flos Pelargonii Shi Niuer Seedling section Pelargonium, grows under the most semi-tropical weather conditions.I State's planting site mainly in the middle regions of the Yunnan Province, the western regions of the Yunnan Province and South-east of Yunnan, also there is plantation on the ground such as Jiangsu, Zhejiang, Sichuan.In the country such as African, European There is cultivation.Geranium Essential is the whole world one of most important quintessence oil of perfume industry, and fragrance is sweet and lasting stability, is usually used in attacking The compositions such as rare, hyacinth, carnation, Syringa oblata Lindl., fragrant coin in evening, Herba Convallariae and violet, umbrella grass can be used as medicine, and acrid in the mouth is warm in nature, main Be used for treating rheumatism, hernia, eczema scrotum, scabies, modern study also show Geranium Essential have antitumor, antibacterial, control Treat the effects such as condyloma acuminatum.
Orange blossom is the citrous flower of Rutaceae, originates in South China, Northeastern India and Central Asia.Mesh Front China plantation area has Zhong County, Chongqing, longevity, Jiang'an, Sichuan, Yichang, Putian, fujian Province, Jianyang, Guangxi Lipu County, Guangdong splendid Pass, Xunwu of Jiangxi, Yu Dou, Luodian county, Ceheng etc..Orange blossom quintessence oil has the simple and elegant fragrance of a flower and fruital, is widely used in daily The fields such as chemical industry, flavorant, food processing and medical product.In essence produces, orange blossom quintessence oil can be applied as head pastil In floral type, GULONG type, the perfume of east type, floral water, fancy soap, cosmetics essence in.In emerging aromatotherapy health care In industry, orange blossom quintessence oil is widely used as both effectiveness composition, has calm, anti-depression, allays nervousness, promotes cell and live The effects such as power, whitening and softening skin, light speckle.
Lavandula angustifolia Shi Chun type section lavandula angustifolia platymiscium, for perennial undershrub.Lavandula angustifolia mainly originates in France, the former Soviet Union, All there are extensively cultivation in the states such as Italy, Britain, Australia, Bulgaria.The Main Cultivation area of China's lavandula angustifolia have Xinjiang, The ground such as Shaanxi.Lavandula angustifolia leaf, stem, flower Herb are giving off a strong fragrance, aromatic flavor and soft, stingless excitation, have no side effect, by widely Be applied to medicine, make up, wash, food service industry.In lavandula angustifolia, essential oil content is higher, because of its fragrant odour, be commonly used for aromatic, Anthelmintic and the raw material of preparation essence, lavandula angustifolia is precious Chinese crude drug and food flavor.There are some researches show lavandula angustifolia can dampness removing, Stomach invigorating, cephalocathartic, for diseases such as anemofrigid cold.Lavandula angustifolia or traditional medication of Xinjiang Uygur medicine, tie up medical it treat Chest and abdomen swelling and pain, flu cough with asthma, dizziness headache, shortness of breath and palpitation, joint osteodynia etc..
Inca inchi is Euphorbiaceae liana, also known as print with Semen arachidis hypogaeae, Plukenetia volubilis Linneo, astral oil rattan, U.S. rattan fruit.Perennial oil plant Plant, originates in South America Amazon River basin rainforest, is initially become wild into family's kind by Inca, in South America print add area by Local original inhabitants apply the history of more than one thousand years.Planting then, can bear fruit then, seed is rich in oils and fats, protein, aminoacid, also Have vitamin A, vitamin E and some other trace element, Inca inchi oil contain extremely abundant unsaturated fatty acid (ω-3, ω-6, ω-9), and vitamin A, E and protein, and three kinds of unsaturated fatty acid contents are up to more than 92%.Inca inchi oil Containing the abundant phenols with antioxidation, wherein the content of γ and methyltocol is more than 2000 mgs/kg, the highest The tocopherol of content makes its taste and quality the most stable during storing.Inca inchi rich in polyunsaturated fatty acid And oil edible be safe, can be cold and dressed with sauce or fried the most edible.
Jojoba is that one originates in Mexican plant, and Jojoba oil is the most just used as various skin care products and makes The sebum being derived from its molecules align and the mankind by the function that, Jojoba oil is magical is closely similar, so, it is very easy to by skin Skin absorbs.Jojoba oil also has the characteristic of a kind of mystery, solidifies during low temperature, and contact skin just can melt immediately and be inhaled by skin Receive.The textural anomaly of Jojoba oil is stable, will not be by high temperature, also unlike other glycerinated skin care productss, and can be at skin Skin layers forms oil film, and Jojoba oil can provide two-layer effect, rapid osmotic absorption, and horny layer softening layer to skin, allows skin become Obtain soft flexible.Another characteristic of Jojoba oil is great hydrophilic, has the function of regulation moisture to skin, and is suitable for All skin quality, Jojoba oil can be additionally used in unimpeded pore, regulation oiliness or the fat secretion of Combination skin, improves skin and send out The state such as inflammation, sensitivity, chronic eczema, pimples.
In the formula of the present invention, Geranium Essential can alleviate pressure, flat comfort anxiety, dejected, make psychological balance;Orange blossom quintessence oil There is calming nerves effect, also can improve neuralgia, have a headache and dazzle dizzy;Herba Lysimachiae foenum-graeci quintessence oil can tranquillizing and allaying excitement, pacify cardiopalmus, improve Headache, dizzy;Inca inchi oil can produce the plant flavour of uniqueness, can releive and loosen health, can antioxidation, nourishing and maintenance skin Skin;Jojoba oil can improve skin condition.Thus, compositions according to embodiments of the present invention has above-mentioned each composition, and will Various functions after above-mentioned each composition is prepared as compositions is provided with good collaborative facilitation, enhances the merit of separate constituent Effect, therefore the compositions of the embodiment of the present invention has and good improves microcirculation, pacifies the effect in terms of neuralgia.
According to one embodiment of present invention, said composition can be health product or cosmetics.Thus said composition has Good improve microcirculation, pacify the effect in terms of neuralgia.
According to another embodiment of the invention, said composition can be not particularly restricted with the form presented.According to this The concrete example of invention, said composition can be in a liquid state, and can use directly as cosmetics quintessence oil, it is possible in one-tenth spray, Aerosol, ointment, ointment, cream, liniment, oil preparation, drop, it is also possible to add champignon instrument, atomising device be easy to people use, Thus improve said composition for improving microcirculation, pacifying the effect in terms of neuralgia.
In a second aspect of the present invention, the present invention proposes a kind of method preparing compositions noted earlier.According to this Bright embodiment, the method includes: by the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, lotus Lotus bar oil mixes, in order to obtain described compositions.
According to a particular embodiment of the invention, above-mentioned composition can be prepared as compound essential Oil form.According to the present invention Concrete example, concrete preparation method can be: by the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, print Add fruit oil, Jojoba oil mixes, in order to obtain mixture;Obtained mixture is put in stirring container, take the photograph 15 Family name's degree stirs under 25 degrees Celsius, in order to mixture is sufficiently mixed;And the mixture of mix homogeneously is carried out subpackage, sealing, To obtain compound essential Oil.
According to a particular embodiment of the invention, above-mentioned composition can be prepared as the form of spray.According to the present invention Concrete example, concrete preparation method can be: by the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, print Add fruit oil, Jojoba oil mixing, in order to obtain mixture;Obtained mixture is dissolved in the mixed solvent of propylene glycol and ethanol In, in order to obtain clear solution;And clear solution is sub-packed in container, load onto valve, roll tight sealing cap, irrigate with pressure filling Isceon and the mixture of dichlorodifluoromethane, in order to obtain spray.
According to a particular embodiment of the invention, above-mentioned composition can be prepared as the form of ointment.According to the present invention Concrete example, concrete preparation method can be: be incorporated in 50 take the photograph mixed to the stearic acid of predetermined ratio, lanoline and glycerol Heat fusing is added, in order to obtain the first mixture under family name's degree;By the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil mixing, in order to obtain the second mixture;First mixture and the second mixture are mixed, in order to To oil phase;Triethanolamine is dissolved in distilled water, heats at 50 c, in order to obtain aqueous phase;And aqueous phase is mixed with oil phase Merge stirring, in order to obtain ointment.
According to a particular embodiment of the invention, above-mentioned composition can be prepared as the form of ointment.According to the present invention Concrete example, concrete preparation method can be: the vaseline of predetermined ratio, lanoline and liquid paraffin is Celsius in 50 The lower fusing of degree, and it is cooled to 40 degrees Celsius, in order to obtain mixture;And the 3rd obtained mixture will add pre-definite proportion The Geranium Essential of example, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil and ethyl hydroxybenzoate, and stir, with Just ointment is obtained.
According to a particular embodiment of the invention, above-mentioned composition can be prepared as the form of liniment.According to the present invention's Concrete example, concrete preparation method can be: the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, print is added Fruit oil, Jojoba oil mix homogeneously, in order to obtain mixture;And obtained mixture will add glycerol mixing, in order to Obtain liniment.
According to a particular embodiment of the invention, above-mentioned composition can be prepared as the form of drop.According to the present invention's Concrete example, concrete preparation method can be: the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, print is added Fruit oil, Jojoba oil mix homogeneously, in order to obtain mixture;And obtained mixture is carried out through drop production technology Processing, in order to obtain drop.
Thus according to the method for the preparation compositions of the above embodiment of the present invention, compositions can be prepared as compound recipe essence Oil, spray, ointment, ointment, liniment and drop, the most more convenient to use, and combination can be improved further Thing for improving microcirculation, pacifying the effect in terms of neuralgia.
According to embodiments of the invention, Inca inchi oil of the present invention be Inca inchi kernel through low-temperature cold pressing, filtration, Obtaining after removing impurities, the quintessence oil that Flos Pelargonii oil of the present invention, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Jojoba oil are all conventional is former Material, therefore compositions of the present invention is safety non-toxic.
According to embodiments of the invention, compositions of the present invention has the microcirculation that improves significantly, pacifies human body Neuralgic effect, and human body is had no side effect.The compositions of the present invention also has the health-care effect improving immunity.
In the third aspect of the invention, according to embodiments of the invention, the present invention proposes above-mentioned composition of the present invention Purposes in preparing preparation.According to a particular embodiment of the invention, said composition can be prepared as the agent being arbitrarily easy to use Type, for example, it is possible to be prepared as the form of spray, aerosol, ointment, ointment, cream, liniment, oil preparation, drop.According to The specific embodiment of the present invention, the above-mentioned preparation with said composition may be used for improving microcirculation, pacifying neuralgia.Thus, Said composition supplies human body with the form of preparation and uses, and then performance improves microcirculation, pacifies neuralgic effect, additionally may be used Play the effect improving immunity.
The beneficial effects of the present invention is:
1, Geranium Essential, orange blossom quintessence oil, Inca inchi oil, Herba Lysimachiae foenum-graeci quintessence oil, the material of Jojoba oil and function thereof are closed It is integrated, to improving microcirculation, pacifying neuralgia there is collaborative facilitation, and there is the effect improving immunity, and respectively Vegetable oil can be dispersed, is more beneficial for absorption of human body.
2, all raw materials in compositions are taken at nature, come from natural, safe and reliable, and raw material sources are extensively easy to get, group Fang Peiwu is scientific and reasonable, determined curative effect, and preparation technology is simple, storing and application safety, low production cost, and steady quality, Product can preserve for a long time, provides new selection for people's daily health caring and application.
Advantages of the present invention will part be given in the following description, and part will become apparent from the description below, or Recognized by the practice of the present invention.
Accompanying drawing explanation
Fig. 1: pacify in neuralgia test, the variation tendency of rat pain score during treatment.
Detailed description of the invention
Example below is to further illustrate the present invention rather than limit the scope of the invention.Need explanation , unless explicitly stated otherwise, the raw material employed in example below is commercially available.
Embodiment 1: the preparation of spray
Its preparation technology is as follows:
1, weigh the kernel of Inca inchi, after low-temperature cold pressing, filtration, remove impurity, make Inca inchi oil, standby;
2, after being mixed according to weighed amount by composition each in prescription, it is dissolved in the propylene glycol of 80mL and the mixed of ethanol (1:1) In bonding solvent, obtain clear solution, be sub-packed in container, load onto valve, roll tight sealing cap, irrigate isceon with pressure filling And the mixture (30:70) of dichlorodifluoromethane, obtain spray.
Embodiment 2: the preparation of ointment
Its preparation technology is as follows: weigh vaseline 1500g, lanoline 1500g, liquid paraffin 1000g under 50 degrees Celsius Fusing, and is cooled to 40 degrees Celsius, each composition being slowly added in above-mentioned prescription, and adds ethyl hydroxybenzoate 40g and stir, Obtain ointment.
Embodiment 3: the preparation of liniment
Its preparation technology is as follows: by adding the mixing of a small amount of glycerol after composition mix homogeneously each in prescription, obtain liniment.
Embodiment 4: the preparation of ointment
Its preparation technology is as follows: be incorporated in 50 degrees Centigrade melt mixed to stearic acid 800g, lanoline 200g, glycerol 100g Change, add each composition in the above-mentioned prescription being pre-mixed the oil phase that stirs to obtain;Triethanolamine 600g is dissolved in distilled water In, at 50 degrees Centigrade, obtain aqueous phase;And aqueous phase is mixed and stirred for oil phase, obtain emulsifiable paste.
Embodiment 5: the preparation of ointment
Its preparation technology is as follows: weigh vaseline 1000g, lanoline 1000g, liquid paraffin 450g melt in 50 degrees Celsius Change, and be cooled to 40 degrees Celsius, in order to obtain mixture, each composition being slowly added in mixture in above-mentioned prescription, and add Enter ethyl hydroxybenzoate 25g to stir, obtain ointment.
Embodiment 6: the preparation of compositions quintessence oil
Its preparation technology is as follows: weigh above-mentioned each raw material, puts in stirring container, takes the photograph 20 with equidirectional with agitator Stir under family name's degree, make each raw material be sufficiently mixed uniformly, subpackage, sealing, obtain compositions quintessence oil.
Embodiment 7: improve microcirculation test
One, material
The quintessence oil spray that the present embodiment is used, is prepared by embodiment 1, specification 20mL/ bottle, it is recommended to use Method is for being sprayed on affected part.
Laboratory animal: body weight is the ripe Wistar rat 36 of 180-220g, male and female half and half are in a good state of health, Thered is provided by Wuhan University Experimental Animal Center, production licence number: SCXK(Hubei Province) 2008-0004.
Two, method
Rat is randomly divided into 3 groups, and often group 12, is divided into blank group, diabetic groups and quintessence oil group.Diabetes model is big Fasting 24 hours before Mus modeling, according to the dosage lumbar injection streptozotocin citric acid-sodium citrate buffer of 60mg/kg (concentration: 0.1mol/L), sets up rat diabetes model.After injecting 72 hours, gather rat tail vein hematometry blood glucose.At random Blood glucose continues 3 days >=16.7mmol/L person and modeling success is described.Matched group buffers to the citric acid-sodium citrate with isodose Liquid.
Quintessence oil group is sprayed on nasal cavity, 0.1mL/100g, blank group and diabetic groups every day to the normal saline with equivalent, It is administered 2 weeks and 4 weeks, measures rat lower limb microcirculatory blood flow, result is carried out statistical analysis.
Three, result
Each group rat lower limb microcirculatory blood flow the results are shown in Table 1, and result shows, compared with blank group, and diabetic groups Rat lower limb microcirculatory blood flow has pole significant difference (P < 0.01), and quintessence oil group is compared with diabetic groups, and rat lower limb are micro- Blood flow has significant difference (P < 0.05).
Table 1 is respectively organized rat microcirculatory blood flow and is compared
Group Quantity Microcirculatory blood flow when 2 weeks Microcirculatory blood flow when 4 weeks
Blank group 12 38.24±4.31 37.59±2.94
Diabetic groups 12 26.97±1.99 25.71±2.33
Quintessence oil group 12 31.87±2.56 29.65±2.46
Embodiment 8: pacify neuralgia test
One, material
The quintessence oil spray that the present embodiment is used, is prepared by embodiment 1, specification 20mL/ bottle, it is recommended to use Method is for being sprayed on affected part.
Laboratory animal: body weight is the ripe Wistar rat 40 of 180-220g, male, is in a good state of health, by force Chinese University Medical College Experimental Animal Center provides, production licence number: SCXK(Hubei Province) 2008-0004.
Two, method
The method using Banded Rats sciatic nerve-trunk makes neuralgia rat model: exposes left sciatic and does, often Slightly ligaturing one operation gutstring every 2mm, Gong Zha tetra-road, offside does sham-operation.Post operation injection scotcil 100,000 U.Modeling Latter 4th day, use photo-thermal to survey pain method and measure its pain score, occur that negative value both less than-1.0s person show modeling for continuous three times Success, for neuralgia rat.
Rat is randomly divided into 2 groups, often group 20, respectively quintessence oil treatment group and model control group.Quintessence oil group is sprayed on every day At rat sciatic nerve, 5s/ time, model control group gives the normal saline with equivalent, is administered 4 weeks, all surveys pain every day period 3 times, Every minor tick 10min.When taking steady statue, the meansigma methods of 3 pain scores is as the pain score of each time point, to result Carry out statistical analysis.
Three, result
Experimental result is shown in Fig. 1, the basic pain score value of two groups of rats respectively (-2.24 ± 0.17), (-2.09 ± 0.24), difference nonsignificance between group.Along with the increase for the treatment of natural law, treatment group rat pain score absolute value is gradually reduced, The change of pain score absolute value all has significant difference (P < 0.05) compared with matched group.Prompting quintessence oil is administered rat Pain has obvious accumulation analgesic activity..
In the description of this specification, reference term " embodiment ", " some embodiments ", " example ", " specifically show Example " or the description of " some examples " etc. means to combine this embodiment or example describes specific features, structure, material or spy Point is contained at least one embodiment or the example of the present invention.In this manual, to the schematic representation of above-mentioned term not Necessarily refer to identical embodiment or example.And, the specific features of description, structure, material or feature can be any One or more embodiments or example in combine in an appropriate manner.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not These embodiments can be carried out multiple change in the case of departing from the principle of the present invention and objective, revise, replace and modification, this The scope of invention is limited by claim and equivalent thereof.

Claims (11)

1. a compositions, it is characterised in that component is as follows:
The Geranium Essential of 60-180 weight portion;
The orange blossom quintessence oil of 20-80 weight portion;
The Herba Lysimachiae foenum-graeci quintessence oil of 30-100 weight portion;
The Inca inchi oil of 20-80 weight portion;And
The Jojoba oil of 100-220 weight portion.
Compositions the most according to claim 1, it is characterised in that the component of described compositions is as follows:
The Geranium Essential of 100 weight portions;
The orange blossom quintessence oil of 40 weight portions;
The Herba Lysimachiae foenum-graeci quintessence oil of 60 weight portions;
The Inca inchi oil of 40 weight portions;And
The Jojoba oil of 160 weight portions.
Compositions the most according to claim 1 and 2, it is characterised in that described compositions is health product or cosmetics,
Optionally, described compositions is the shape of spray, aerosol, ointment, ointment, cream, liniment, oil preparation or drop Formula.
4. the method for the compositions prepared described in claim 1 or 2, it is characterised in that including: by the India of predetermined ratio Certain herbaceous plants with big flowers quintessence oil, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil mixing, in order to obtain described compositions.
Method the most according to claim 4, it is characterised in that including:
The Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil are mixed, in order to Obtain mixture;
Obtained mixture is put in stirring container, stir under 15 degrees Celsius to 25 degrees Celsius, in order to described mixture It is sufficiently mixed;And
The described mixture of mix homogeneously is carried out subpackage, sealing, in order to obtain compound essential Oil.
Method the most according to claim 4, it is characterised in that including:
By the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil mixing, in order to obtain Mixture;
Obtained mixture is dissolved in the mixed solvent of propylene glycol and ethanol, in order to obtain clear solution;And
Described clear solution is sub-packed in container, loads onto valve, roll tight sealing cap, irrigate isceon and two with pressure filling The mixture of dichlorodifluoromethane, in order to obtain spray.
Method the most according to claim 4, it is characterised in that including:
The stearic acid of predetermined ratio, lanoline and glycerol mixed and adds heat fusing at 50 c, in order to obtaining first Mixture;
By the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil mixing, in order to obtain Second mixture;
Described first mixture and the second mixture are mixed, in order to obtain oil phase;
Triethanolamine is dissolved in distilled water, heats at 50 c, in order to obtain aqueous phase;And
Described aqueous phase is mixed and stirred for oil phase, in order to obtain ointment.
Method the most according to claim 4, it is characterised in that including:
The vaseline of predetermined ratio, lanoline and liquid paraffin are melted under 50 degrees Celsius, and is cooled to 40 degrees Celsius, with Just mixture is obtained;And
The 3rd obtained mixture will add the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi Oil, Jojoba oil and ethyl hydroxybenzoate, and stir, in order to obtain ointment.
Method the most according to claim 4, it is characterised in that including:
By the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil mix homogeneously, in order to Obtain mixture;And
Obtained mixture will add glycerol mixing, in order to obtain liniment.
Method the most according to claim 4, it is characterised in that including:
By the Geranium Essential of predetermined ratio, orange blossom quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, Inca inchi oil, Jojoba oil mix homogeneously, in order to Obtain mixture;And
Obtained mixture is processed through drop production technology, in order to obtain drop.
The compositions described in 11. claim 1 or 2 purposes in preparing preparation, described preparation be used for improving microcirculation and/or Pacify neuralgia.
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