CN105902667A - Drops for treating pinkeye - Google Patents
Drops for treating pinkeye Download PDFInfo
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- CN105902667A CN105902667A CN201610385970.7A CN201610385970A CN105902667A CN 105902667 A CN105902667 A CN 105902667A CN 201610385970 A CN201610385970 A CN 201610385970A CN 105902667 A CN105902667 A CN 105902667A
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- drops
- canton love
- pea vine
- filtrate
- chinese magnoliavine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention relates to the field of traditional Chinese medicine technology, and concretely relates to drops for treating pinkeye. The drops are prepared by the following raw materials: lotus stamen, Chinese magnoliavine fruits, canton love-pea vine, Rhynchosia volubilis, masson pine needles, and borneol; during preparation, Rhynchosia volubilis and Chinese magnoliavine fruits are grilled and pulverized, ethanol whose concentration is 95% is added, ultrasonic extraction is carried out with microwave for 60-65 minutes, and filtrate of Rhynchosia volubilis and Chinese magnoliavine fruits is obtained by filtering; lotus stamen, canton love-pea vine and masson pine needles are pulverized, ethanol whose concentration is 70% is added according to a mass ratio 1:10, ultrasonic extraction is carried out with microwave for 18-22 minutes, and filtrate of lotus stamen, canton love-pea vine and masson pine needles is obtained; the filtrates are mixed, vacuum rectification is carried out, fraction at the top of a rectifying tower at 70-75 DEG C is collected, the fraction and borneol are mixed, and the drops for treating pinkeye are obtained. The drops are safe and effective without side-effects for human body, and the drops do not have irritative reactions for eyes; after usage, the eyes feel comfortable, and when the drops are not used, side-effects do not appear.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, be specifically related to a kind of drops treating blood-shoot-eye illness.
Background technology
Blood-shoot-eye illness is to be infected, by bacterium, a kind of common acute Epidemic ophthalmic caused.It is the most congested that it is mainly characterized by conjunctiva, purulence or mucopurulent secretion thing, patient is conscious suffers from urticant sensation of the eye such as foreign body sensation, there is eyelid heavy time serious, photophobia is shed tears and burning heat sensation, sometimes it is attached to anterior corneal surface lesser ring of Merkel because of secretion, cause temporary blurring of vision, eyesight can be recovered after flushing, owing to inflammatory stimulus produces a large amount of mucopurulent secretion things, can realize when patient wakes up morning that the secreted thing of upper lower eyelid is sticked together, when pathology is invaded and during cornea, photophobia, pain and substantially increasing the weight of depending on the symptom such as go down, small number of patients can have the infection of the upper respiratory tract or other constitutional symptoms simultaneously.At present many employing 10% sulfanilyl acyl sodium during patient therapy, 0.25% chloramphenicol, 0.5%～1.0% erythromycin liquid or neomycin carry out dripping with or paintings treat, wherein sulfanilyl acyl sodium has local irritation, and bacterium is easily generated drug resistance to this product, chloramphenicol and erythromycin then have certain damage to liver kidney, and these several drops need to coordinate antibiotic to treat, and are used alone result for the treatment of the best.
Summary of the invention
The present invention provides a kind of drops treating blood-shoot-eye illness, and this drops is made up of following Chinese medicine material:
Stamen nelumbini 30-32 part (dry weight), fruit of Chinese magnoliavine 4-6 part (dry weight), Canton love-pea vine 4-6 part (dry weight), deer beans 10-14 part (dry weight), Lignum Pini Nodi pine needle 5-8(dry weight), borneol 2-3 part；
During making, deer beans, fruit of Chinese magnoliavine low baking temperature being scorched 10-15 minute, be ground into 30-40 mesh, adding concentration by the mass ratio of 1:8 in Xiang Ludou, Fructus Schisandrae Chinensis powder is the ethanol of 95%, ultrasonic extraction 60-65 minute under the microwave power of 95-98W, filters to obtain deer beans, fruit of Chinese magnoliavine filtrate；
Stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle are crushed to 80 mesh, adding concentration by the mass ratio of 1:10 in stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle powder is the ethanol of 70%, ultrasonic extraction 18-22 minute under the microwave power of 115-120W, filters to obtain stamen nelumbini, Canton love-pea vine, masson pine filtrate；
After deer beans, fruit of Chinese magnoliavine filtrate being mixed with stamen nelumbini, Canton love-pea vine, masson pine filtrate, under vacuum is 0.085mpa, carry out rectification under vacuum, collect rectifying tower top 70-75 DEG C gained cut, after mixing with borneol, obtain the drops of this treatment blood-shoot-eye illness.
Drops of the present invention is safe and effective, human body is had no side effect, instill vacuum response in eye, comfort level is good, disable rear without any side effects, the extracted active ingredient obtained of raw material is to Diplococcus pneumopniae bacillus, hemophilus influenzae, staphylococcus aureus and streptococcus have stronger suppression and kill effect, clinical tests prove that according to clinical verification, to acute, chronic blood-shoot-eye illness is respectively provided with preferably treats curative effect, wherein, Acute Red Eye typically drips can cure with 1-2 days, cure rate is up to 100%, chronic blood-shoot-eye illness is typically dripped and can be cured with 15-20 days, cure rate is up to 96.15%.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be described, but protection scope of the present invention is not limited in scope described by embodiment,
Embodiment 1, a kind of drops treating blood-shoot-eye illness, this drops is made up of following Chinese medicine material:
Stamen nelumbini 30 parts (dry weight), 4 parts of the fruit of Chinese magnoliavine (dry weight), Canton love-pea vine 4 parts (dry weight), deer beans 10 parts (dry weight), Lignum Pini Nodi pine needle 5(dry weight), borneol 2 parts；
During making, Jiang Ludou, fruit of Chinese magnoliavine low baking temperature scorch 10 minutes, are ground into 30 mesh, and adding concentration by the mass ratio of 1:8 in Xiang Ludou, Fructus Schisandrae Chinensis powder is the ethanol of 95%, and deer beans, fruit of Chinese magnoliavine filtrate are filtered to obtain in ultrasonic extraction 60 minutes under the microwave power of 95W；
Stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle are crushed to 80 mesh, adding concentration by the mass ratio of 1:10 in stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle powder is the ethanol of 70%, ultrasonic extraction 18 minutes under the microwave power of 115W, filter to obtain stamen nelumbini, Canton love-pea vine, masson pine filtrate；
After deer beans, fruit of Chinese magnoliavine filtrate being mixed with stamen nelumbini, Canton love-pea vine, masson pine filtrate, under vacuum is 0.085mpa, carry out rectification under vacuum, collect 70 DEG C of gained cuts of rectifying tower top, after mixing with borneol, obtain the drops of this treatment blood-shoot-eye illness.
Embodiment 2, a kind of drops treating blood-shoot-eye illness, this drops is made up of following Chinese medicine material:
Stamen nelumbini 32 parts (dry weight), 6 parts of the fruit of Chinese magnoliavine (dry weight), Canton love-pea vine 6 parts (dry weight), deer beans 14 parts (dry weight), Lignum Pini Nodi pine needle 8(dry weight), borneol 3 parts；
During making, Jiang Ludou, fruit of Chinese magnoliavine low baking temperature scorch 15 minutes, are ground into 40 mesh, and adding concentration by the mass ratio of 1:8 in Xiang Ludou, Fructus Schisandrae Chinensis powder is the ethanol of 95%, and deer beans, fruit of Chinese magnoliavine filtrate are filtered to obtain in ultrasonic extraction 65 minutes under the microwave power of 98W；
Stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle are crushed to 80 mesh, adding concentration by the mass ratio of 1:10 in stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle powder is the ethanol of 70%, ultrasonic extraction 18-22 minute under the microwave power of 120W, filters to obtain stamen nelumbini, Canton love-pea vine, masson pine filtrate；
After deer beans, fruit of Chinese magnoliavine filtrate being mixed with stamen nelumbini, Canton love-pea vine, masson pine filtrate, under vacuum is 0.085mpa, carry out rectification under vacuum, collect 75 DEG C of gained cuts of rectifying tower top, after mixing with borneol, obtain the drops of this treatment blood-shoot-eye illness.
Embodiment 3, a kind of drops treating blood-shoot-eye illness, this drops is made up of following Chinese medicine material:
Stamen nelumbini 30.6 parts (dry weight), 4.5 parts of the fruit of Chinese magnoliavine (dry weight), Canton love-pea vine 4.5 parts (dry weight), deer beans 11 parts (dry weight), Lignum Pini Nodi pine needle 6(dry weight), borneol 2.3 parts；
During making, Jiang Ludou, fruit of Chinese magnoliavine low baking temperature scorch 12 minutes, are ground into 32 mesh, and adding concentration by the mass ratio of 1:8 in Xiang Ludou, Fructus Schisandrae Chinensis powder is the ethanol of 95%, and deer beans, fruit of Chinese magnoliavine filtrate are filtered to obtain in ultrasonic extraction 62 minutes under the microwave power of 96W；
Stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle are crushed to 80 mesh, adding concentration by the mass ratio of 1:10 in stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle powder is the ethanol of 70%, ultrasonic extraction 19 minutes under the microwave power of 117W, filter to obtain stamen nelumbini, Canton love-pea vine, masson pine filtrate；
After deer beans, fruit of Chinese magnoliavine filtrate being mixed with stamen nelumbini, Canton love-pea vine, masson pine filtrate, under vacuum is 0.085mpa, carry out rectification under vacuum, collect 72 DEG C of gained cuts of rectifying tower top, after mixing with borneol, obtain the drops of this treatment blood-shoot-eye illness.
Embodiment 4, a kind of drops treating blood-shoot-eye illness, this drops is made up of following Chinese medicine material:
Stamen nelumbini 31.4 parts (dry weight), 5.7 parts of the fruit of Chinese magnoliavine (dry weight), Canton love-pea vine 5.7 parts (dry weight), deer beans 13 parts (dry weight), Lignum Pini Nodi pine needle 7(dry weight), borneol 2.6 parts；
During making, Jiang Ludou, fruit of Chinese magnoliavine low baking temperature scorch 1415 minutes, are ground into 38 mesh, and adding concentration by the mass ratio of 1:8 in Xiang Ludou, Fructus Schisandrae Chinensis powder is the ethanol of 95%, and deer beans, fruit of Chinese magnoliavine filtrate are filtered to obtain in ultrasonic extraction 63 minutes under the microwave power of 97W；
Stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle are crushed to 80 mesh, adding concentration by the mass ratio of 1:10 in stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle powder is the ethanol of 70%, ultrasonic extraction 21 minutes under the microwave power of 117W, filter to obtain stamen nelumbini, Canton love-pea vine, masson pine filtrate；
After deer beans, fruit of Chinese magnoliavine filtrate being mixed with stamen nelumbini, Canton love-pea vine, masson pine filtrate, under vacuum is 0.085mpa, carry out rectification under vacuum, collect 73 DEG C of gained cuts of rectifying tower top, after mixing with borneol, obtain the drops of this treatment blood-shoot-eye illness.
Physical data,
The present invention treats the drops of blood-shoot-eye illness and has treated blood-shoot-eye illness patient 108 example, the wherein male sex 75, women 33, age reckling 8 years old, the maximum 70 years old, acute red eye patient 82 example, chronic blood-shoot-eye illness patient 26 example altogether since putting into experiment；
During treatment, daily drops treating blood-shoot-eye illness by the present invention of above-mentioned patient, each every drips with 1ml, drips every day with 5 times, and wine for giving off smoking, maror, normally works and rests, and notes protecting eye not by environmental stimuli.
Result: acute red eye patient cures after dripping with 1-2 days, and cure rate is 100%.
Chronic blood-shoot-eye illness patient cures after dripping with 15-20 days, and cure rate is 96.15%.
Wherein, after patient terminates with treatment during treating, this drops is showed no side effect generation.
Claims (3)
1. the drops treating blood-shoot-eye illness, it is characterised in that this drops is made up of the Chinese medicine material of following parts by weight:
Stamen nelumbini 30-32 part, fruit of Chinese magnoliavine 4-6 part, Canton love-pea vine 4-6 part, deer beans 10-14 part, Lignum Pini Nodi pine needle 5-8, borneol 2-3 part.
A kind of drops treating blood-shoot-eye illness the most according to claim 1, it is characterised in that:
Described Chinese medicine material is when preparing by weight, and stamen nelumbini, the fruit of Chinese magnoliavine, Canton love-pea vine, deer beans, Lignum Pini Nodi pine needle all take dry weight.
A kind of drops treating blood-shoot-eye illness the most according to claim 1, it is characterised in that this drops make time,
During making, deer beans, fruit of Chinese magnoliavine low baking temperature being scorched 10-15 minute, be ground into 30-40 mesh, adding concentration by the mass ratio of 1:8 in Xiang Ludou, Fructus Schisandrae Chinensis powder is the ethanol of 95%, ultrasonic extraction 60-65 minute under the microwave power of 95-98W, filters to obtain deer beans, fruit of Chinese magnoliavine filtrate；
Stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle are crushed to 80 mesh, adding concentration by the mass ratio of 1:10 in stamen nelumbini, Canton love-pea vine, Lignum Pini Nodi pine needle powder is the ethanol of 70%, ultrasonic extraction 18-22 minute under the microwave power of 115-120W, filters to obtain stamen nelumbini, Canton love-pea vine, masson pine filtrate；
After deer beans, fruit of Chinese magnoliavine filtrate being mixed with stamen nelumbini, Canton love-pea vine, masson pine filtrate, under vacuum is 0.085mpa, carry out rectification under vacuum, collect rectifying tower top 70-75 DEG C gained cut, after mixing with borneol, obtain the drops of this treatment blood-shoot-eye illness.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610385970.7A CN105902667A (en) | 2016-06-03 | 2016-06-03 | Drops for treating pinkeye |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610385970.7A CN105902667A (en) | 2016-06-03 | 2016-06-03 | Drops for treating pinkeye |
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| CN105902667A true CN105902667A (en) | 2016-08-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610385970.7A Pending CN105902667A (en) | 2016-06-03 | 2016-06-03 | Drops for treating pinkeye |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1399995A (en) * | 2001-08-01 | 2003-03-05 | 上海中医药大学附属龙华医院 | Chinese medicine preparation containing cortex fraxini and its preparation method |
| CN1965877A (en) * | 2006-11-06 | 2007-05-23 | 赵因 | Chinese medicinal eye drop for treating bacteria and virus infected conjunctivitis |
| CN102755430A (en) * | 2012-07-25 | 2012-10-31 | 白杰 | Traditional Chinese medicine composition for treating conjunctivitis by external use and applications of composition |
| CN103099975A (en) * | 2013-01-09 | 2013-05-15 | 张大雷 | Traditional Chinese medicine preparation for treating pinkeye |
-
2016
- 2016-06-03 CN CN201610385970.7A patent/CN105902667A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1399995A (en) * | 2001-08-01 | 2003-03-05 | 上海中医药大学附属龙华医院 | Chinese medicine preparation containing cortex fraxini and its preparation method |
| CN1965877A (en) * | 2006-11-06 | 2007-05-23 | 赵因 | Chinese medicinal eye drop for treating bacteria and virus infected conjunctivitis |
| CN102755430A (en) * | 2012-07-25 | 2012-10-31 | 白杰 | Traditional Chinese medicine composition for treating conjunctivitis by external use and applications of composition |
| CN103099975A (en) * | 2013-01-09 | 2013-05-15 | 张大雷 | Traditional Chinese medicine preparation for treating pinkeye |
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Application publication date: 20160831 |