CN105878689A - 一种治疗强直性脊柱炎的中药 - Google Patents

一种治疗强直性脊柱炎的中药 Download PDF

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CN105878689A
CN105878689A CN201610381435.4A CN201610381435A CN105878689A CN 105878689 A CN105878689 A CN 105878689A CN 201610381435 A CN201610381435 A CN 201610381435A CN 105878689 A CN105878689 A CN 105878689A
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迟涛胜
仲崇华
史永安
隋海明
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Abstract

本发明涉及一种治疗强直性脊柱炎的中药，是由下列原料药物按一定重量配比组成：桂枝，独活，生地，熟地，桑寄生，川断，杜仲，当归，川芎，鹿角胶，忍冬藤，鸡血藤，络石藤，制乌梢蛇，炙麻黄，知母，白芍，炙甘草。本发明中药配制简单，成本低，药源广，疗效快，治愈率高，无毒副作用。治疗强直性脊柱炎有效率100％，治愈率98％，好转2％。

Description

一种治疗强直性脊柱炎的中药
技术领域
本发明涉及一种治疗强直性脊柱炎的中药，属于中药技术领域。
背景技术
强直性脊柱炎属于自身免疫性疾病，是风湿科脊柱关节病中常见的一种，其特点是以HLA-B27为遗传易感因子，以四肢大关节及椎间盘纤维环及其附近结缔组织纤维化和骨化为病理表现，也可伴有关节外表现如虹膜炎、炎症性肠病、心脏传导障碍、淀粉样变及双上肺间质纤维化。如果病情得不到控制，会导致脊柱、关节强直，乃至残疾严重影响患者正常生活。本病属中医“痹证”、“大偻”范畴。《素问·骨空论》说:“督脉为病，脊强反折，腰痛不可以摇转。”临床可辨证分为肝肾亏虚、气血不足、肾虚督寒，瘀血阻络贯穿疾病始终。
发明内容
本发明针对现有技术之不足，提供一种治疗强直性脊柱炎的中药，其特征在于原料药物及重量配比为：桂枝9-12g，独活10-15g，生地15-20g，熟地15-20g，桑寄生10-15g，川断10-15g，杜仲10-20g，当归9-12g，川芎9-12g，鹿角胶6-10g，忍冬藤10-30g，鸡血藤10-30g，络石藤10-30g，制乌梢蛇3-6g，炙麻黄3-6g，知母6-10g，白芍10-30g，炙甘草3-6g。
优选用量：桂枝12g，独活10g，生地15g，熟地15g，桑寄生15g，川断15g，杜仲20g，当归12g，川芎12g，鹿角胶10g，忍冬藤30g，鸡血藤30g，络石藤30g，制乌梢蛇6g，炙麻黄6g，知母10g，白芍30g，炙甘草6g。
本发明中药配制简单，成本低，药源广，疗效快，治愈率高，无毒副作用。
药理分析：本方所治之症是由于肾虚督寒，瘀血阻滞经络所致。方中白芍敛阴养血，柔肝止痛为君药。生地、知母清热凉血，熟地、当归滋阴祛瘀，川芎行气活血共为臣药。炙麻黄、桂枝祛风、温通经络配合鹿角胶驱除督寒；忍冬藤、鸡血藤、络石藤，祛风宣痹，行血补血，舒筋活络；独活、牛膝、续断、桑寄生活血化瘀，补肝肾，强腰膝；乌梢蛇搜刮通络，通痹共为佐药，炙甘草补中益气，缓和药性，又能配芍药缓急止痛，为使药。诸药合用，共奏补肝肾、止痹痛，活血祛瘀，清热利湿之功效。
剂型及用法：本发明中药剂型为汤剂，水煎服，每日一剂，煎煮两遍。头煎加凉水800ml，浸泡两小时，武火煮沸后改文火续煎30分钟，取汁约200ml；二煎加热水800ml，武火煮沸后改文火续煎50分钟，取汁约200ml。两煎所得药汁混合，早晚饭后2小时各服200ml，温开水送服，服药期间忌食辛辣寒凉食物。
具体实施方式：
实施例1：一种治疗强直性脊柱炎的中药，是由下列原料药物和重量配比制成：桂枝9-12g，独活10-15g，生地15-20g，熟地15-20g，桑寄生10-15g，川断10-15g，杜仲10-20g，当归9-12g，川芎9-12g，鹿角胶6-10g，忍冬藤10-30g，鸡血藤10-30g，络石藤10-30g，制乌梢蛇3-6g，炙麻黄3-6g，知母6-10g，白芍10-30g，炙甘草3-6g。
实施例2：一种治疗强直性脊柱炎的中药，其中各种原料药物的优选重量配比为：桂枝12g，独活10g，生地15g，熟地15g，桑寄生15g，川断15g，杜仲20g，当归12g，川芎12g，鹿角胶10g，忍冬藤30g，鸡血藤30g，络石藤30g，制乌梢蛇6g，炙麻黄6g，知母10g，白芍30g，炙甘草6g。
临床疗效总结：
一、一般资料：共收治病人30例，其中男性23例，女性7例；年龄在18-56岁之间。平均28.1±4.2岁。
二、诊断标准：
1、主证：所有患者均符合1984年修订纽约标准，即腰痛、僵3个月以上，活动改善，休息无改善；腰椎额状面和矢状面活动受限；胸廓活动度低于相应年龄、性别的正常人3条临床症状标准中至少1条，同时双侧骶髂关节炎Ⅱ～Ⅲ级或单侧骶髂关节炎Ⅲ～IV级。
2、体征：腰椎生理弧度存在，腰骶不适感，骶髂关节压痛（++），脊柱前屈、后伸、侧弯、转动受限，四字试验（+），直腿抬高试验（+），四肢肌力降低，主被动站立、弯腰困难或受限，骶棘肌痉挛（+-），苔薄黄腻，脉细弦。
三、疗效判定标准：
1、治愈：临床症状消失，站立及行走正常。
2、好转：临床症状减轻。
四、治疗效果：服药一周为一疗程，多数患者两疗程症状明显减轻，三个疗程痊愈。有效率100％，治愈率98％，好转2％。
五、典型病例：
1、田某，男，42岁，农民。2014年10月就诊。素有腰脊疼痛，累及两侧骶髂关节，实验室检HLAB-27（+），曾做过推拿、理疗，服过布洛芬、双氯芬酸钠等药，但病情反复，时轻时重，不能正常劳动。今来诊，要求服用中药治疗。查体：腰脊及两侧骶髂关节疼痛，骶棘肌痉挛（+-），弯腰困难，四肢少温，苔薄黄腻，脉沉弦。给予上述中药服用两疗程，症状明显减轻，继服三疗程，诸症消失而痊愈，半年后随访未复发。
2、陶某，女，31岁，银行职员。2015年8月初诊。因“双下肢、腰部疼痛，活动受限10月，加重1周”入院。患者10月前出现双下肢关节、腰部疼痛，表现为站立困难，腰骶疼痛不适，活在我院查HLA-B27阳性，骶髂关节CT等，被诊断为“AS”，予西乐葆胶囊、柳氮磺吡啶片等治疗，效果不明显，疼痛反复。要求服用中草药治疗。查体：骶髂关节、双膝关节、踝关节压痛阳性，脊柱前屈、后伸、侧弯、转动受限，四字试验（+），直腿抬高试验（+），四肢肌力V级，双下肢踝部肿胀伸展受限，舌质暗红，苔白润，脉弦紧。考虑为肝肾两虚，督脉虚寒，给予上述中药服用一疗程，症状明显缓解，继服三疗程巩固治疗，诸症消失而痊愈，半年后随访未复发。

Claims (1)

1.一种治疗强直性脊柱炎的中药，其特征在于原料药物及重量配比为：桂枝9-12g，独活10-15g，生地15-20g，熟地15-20g，桑寄生10-15g，川断10-15g，杜仲10-20g，当归9-12g，川芎9-12g，鹿角胶6-10g，忍冬藤10-30g，鸡血藤10-30g，络石藤10-30g，制乌梢蛇3-6g，炙麻黄3-6g，知母6-10g，白芍10-30g，炙甘草3-6g。
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CN102526245A (zh) * 2012-01-18 2012-07-04 刘家东 通化丸
CN102846915A (zh) * 2012-09-28 2013-01-02 郑州中医骨伤病医院 治疗强直性脊柱炎的滋阴补肾丸
CN103893427A (zh) * 2014-04-15 2014-07-02 韩世昌 一种治疗强直性脊柱炎的中药组合物及其制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1403103A (zh) * 2001-08-30 2003-03-19 镇水清 痹痛丸及其制备方法
CN102526245A (zh) * 2012-01-18 2012-07-04 刘家东 通化丸
CN102846915A (zh) * 2012-09-28 2013-01-02 郑州中医骨伤病医院 治疗强直性脊柱炎的滋阴补肾丸
CN103893427A (zh) * 2014-04-15 2014-07-02 韩世昌 一种治疗强直性脊柱炎的中药组合物及其制备方法

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