CN105853304A - Traditional Chinese medicine composition with skin whitening effect as well as preparation method and application thereof - Google Patents
Traditional Chinese medicine composition with skin whitening effect as well as preparation method and application thereof Download PDFInfo
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- CN105853304A CN105853304A CN201610382061.8A CN201610382061A CN105853304A CN 105853304 A CN105853304 A CN 105853304A CN 201610382061 A CN201610382061 A CN 201610382061A CN 105853304 A CN105853304 A CN 105853304A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention provides a traditional Chinese medicine composition with a skin whitening effect as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw medicines in parts by weight: 3-24 parts of costus root, 1-18 parts of phyllanthus emblica, 2-16 parts of licorice, 1-22 parts of bighead atractylodes rhizome, 3-10 parts of coptis root, 1-15 parts of forsythia, 2-20 parts of sea buckthorn and 1-9 parts of hyacinth bletilla. The invention also provides a skin care cosmetic which contains the traditional Chinese medicine composition and skin care auxiliary materials and has a skin whitening effect. The traditional Chinese medicine composition can promote blood circulation of capillary vessels in the skin, improve the nutrition supply of the skin, enhance the elasticity of the skin and reduce the keratinization and pigmentation of the skin so as to achieve the aim of effectively whitening the skin; and the traditional Chinese medicine composition is free of toxic or side effect on the human body and is favorable for being popularized and applied.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition with white-skinned face function, particularly relate to a kind of by the Radix Aucklandiae, emblic
Son, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Coptidis, Fructus Forsythiae, Fructus Hippophae and the Pseudobulbus Bletillae (Rhizoma Bletillae) are the Chinese medicine composition made of raw material and preparation thereof
Method and application.
Background technology
Melanin is present in a kind of protein of everyone skin base layer, and ultraviolet irradiation can make black
Element produces change, generates a kind of material protecting skin, moving layer by layer via cellular metabolism again, has arrived flesh
Skin epidermal area, thus define the skin problems such as seen mottle, the colour of skin be irregular, dark yellow.Female face
Pigmentation, tarnish, dark yellow etc. be the young and middle-aged women face that especially this age working woman is most commonly seen
Portion's skin problem, affects emotion and the life of young and middle-aged women.
The Effect raw material that at present skin-lightening cosmetic of commercial type is added mainly include arbutin, kojic acid,
One or more in the raw material such as ascorbic acid, cell growth factor, containing the skin-lightening cosmetic of above-mentioned raw materials
Also skin is caused while there is whitening effect certain injury, and makes product easily produce change
The phenomenon that complexion changed taste is unstable.Along with science and technology development, growth in the living standard and to skin health consciousness
Improving, people are more and more higher to the attention rate of cosmetics, and Chinese medicine natural, green, safe and effective is beautiful
Albefaction cosmetic particularly receives publicity.Chinese medicine skin-lightening cosmetic is little with its toxic and side effects, the occupancy volume of the market share
Expand year by year, but be usually present the problems such as curative effect is rapid not, effective ingredient is inconspicuous.
Summary of the invention
It is an object of the invention to overcome the Chinese medicine composition whitening effect in the presence of prior art undesirable,
The traditional Chinese medicinal material raw materials irrational above-mentioned deficiency of collocation, it is provided that a kind of Chinese medicine composition with white-skinned face function.
Another object of the present invention is to propose the extracting method of a kind of above-mentioned Chinese medicine composition active component.
The third object of the present invention is the skin protection cosmetics combination proposing to utilize above-mentioned Chinese medicine extract to prepare
Thing.
The fourth object of the present invention is to propose the optimal preparation method of a kind of above-mentioned skin care cosmetic compositions.
In order to realize foregoing invention purpose, the invention provides techniques below scheme:
A kind of Chinese medicine composition with white-skinned face function, described compositions is by the crude drug of following weight
Make: the Radix Aucklandiae 3～24 parts, Fructus Phyllanthi 1～18 parts, Radix Glycyrrhizae 2～16 parts, the Rhizoma Atractylodis Macrocephalae 1～22 parts, Rhizoma Coptidis 3～10
Part, Fructus Forsythiae 1～15 parts, Fructus Hippophae 2～20 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1～9 parts.
The invention thinking of the present invention is: according to tcm theory, in conjunction with clinical practice, from Chinese medicine material treasure-house
In filter out the pure middle YAOJING of the Radix Aucklandiae, Fructus Phyllanthi, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Coptidis, Fructus Forsythiae, Fructus Hippophae and the Pseudobulbus Bletillae (Rhizoma Bletillae) eight taste
System forms, and regulates the weight of each raw material, makes to play between each raw material the effect of Synergistic, energy
Enough promote that in skin, the blood of blood capillary follows bad, to improve skin nutrition supply, strengthens skin elasticity, subtracts
Few Keratoderma and pigmentation, reach the purpose of whitening effect.
In Chinese medicine composition of the present invention, the pharmacological action of each raw medicinal material is respectively as follows: Radix Aucklandiae acrid in the mouth, hardship, property
Temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Abdominal distention is coerced for breast,
Weight after dysentery, food stagnation does not disappears, anorexia.Radix Aucklandiae (roasted) reality intestinal antidiarrheal.For stomachache of having loose bowels.
Fructus Phyllanthi, bitter but sweet flavor, cold in nature.Attach to the lung and stomach meridians.Relieving sore-throat by clearing away heat, moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst." four
River Chinese medicinal herbal ": " entering spleen, stomach paralysis is reduced phlegm, and promotes the production of body fluid, cough-relieving, removing toxic substances.Cure cold heating, pharyngalgia of coughing,
Diphtheria, restlessness and fever with thirst.”
Radix Glycyrrhizae, nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp, have a QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, dispel
Phlegm and relieving cough, relieving spasm to stop pain, the function of the mediation property of medicine.
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.
For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Rhizoma Coptidis, heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomit acid regurgitation, dysentery, jaundice, height
Hot coma, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache is quenched one's thirst, carbuncle furuncle；Outward
Controlling eczema, eczema, auditory meatus is suppurated.
Fructus Forsythiae, nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian；Heat clearing away, removing toxic substances, eliminating stagnation, detumescence；Control warm,
Erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Fructus Hippophae, warm in nature, sour-puckery flavor, there is promoting blood circulation to remove blood stasis, the chest stuffiness relieving that reduces phlegm, promoting the production of body fluid to quench thirst, clearing away heat to stop diarrhea
Effect, cure mainly traumatic injury, lung abscess, cough with copious phlegm, dyspnea, dyspepsia, high thermal burn cloudy,
The diseases such as enteritis and dysentery, stomachache, amenorrhea.
The Pseudobulbus Bletillae (Rhizoma Bletillae), meridian distribution of property and flavor: bitter in the mouth, sweet, puckery, cold in nature, return lung, liver, stomach warp.There is astringing to arrest bleeding,
The merit of detumescence and promoting granulation, for all cards of interior external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc..
Applicant finds through many experiments, and Chinese medicine composition of the present invention is by the raw material of above-mentioned weight
Make, can preferably play the synergistic function of each raw material components, not only can whitening effect skin, with
Time instant effect, have no side effect.
Preferably, described compositions is made up of the crude drug of following weight: the Radix Aucklandiae 5～20 parts, emblic
Son 3～15 parts, Radix Glycyrrhizae 2～15 parts, the Rhizoma Atractylodis Macrocephalae 1～18 parts, Rhizoma Coptidis 3～7 parts, Fructus Forsythiae 2～12 parts, Fructus Hippophae 2～14
Part and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1～6 parts.
It is further preferred that described compositions is made up of the raw material of following weight proportion: described compositions by under
The raw material of row weight proportion is made: the Radix Aucklandiae 10～15 parts, Fructus Phyllanthi 5～10 parts, Radix Glycyrrhizae 5～12 parts, the Rhizoma Atractylodis Macrocephalae
2～9 parts, Rhizoma Coptidis 3～6 parts, Fructus Forsythiae 4～8 parts, Fructus Hippophae 3～10 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1～5 parts.
The most preferably, described compositions is made up of the raw material of following weight proportion: the Radix Aucklandiae 12 parts, Fructus Phyllanthi
9 parts, 9 parts of Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 6 parts, Rhizoma Coptidis 6 parts, Fructus Forsythiae 6 parts, Fructus Hippophae 6 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 3 parts.
By above preferred, the curative effect of Chinese medicine composition can be improved further.
A kind of Chinese medicine extract with white-skinned face function, described extract is normal through Chinese materia medica by combinations of the above thing
Rule extracting method extracts and obtains.
Above-mentioned Chinese medicine extract can be prepared as various skin care item in conjunction with skin protection cosmetics field customary adjuvant,
Such as facial film, essence, face frost and cosmetic water etc..
A kind of above-mentioned Chinese medicine composition prepare extract method, specifically comprise the following steps that
(1) each crude drug is weighed according to said ratio；
(2) described crude drug is separately added into 75% ethanol of 8～10 times of volumes, 55 DEG C of reflux, extract, three times,
Extraction time is respectively 2.0h, 1.5h, 1.5h, filters, merges 3 filtrates；
(3) by described filtrate recycling ethanol and concentrate, then by the concentrated solution mix homogeneously of each crude drug, it is dried,
Obtain activity extract.
Six kinds of concentrated solutions are mixed after being concentrated by the alcohol extract of crude drug by above-mentioned steps again, prepared
The effective ingredient of activity extract higher.
Preparation method of the present invention can effectively extract the effective ingredient in each crude drug so that it is more preferably
Play Synergistic effect.
A kind of skin care cosmetic compositions with white-skinned face function, described skin care cosmetic compositions is by following matter
The raw material of amount percentage ratio is made:
Described Chinese medicine extract is Chinese medicine extract prepared by said method.
A kind of method preparing above-mentioned skin care cosmetic compositions, it is characterised in that described in specifically comprise the following steps that
(1) Chinese medicine extract, guar hydroxypropyltrimonium chloride are uniformly mixed at 65-75 DEG C
5-15min, puts 20-30min afterwards at 65-75 DEG C, forms mixed liquor；
(2) mixed liquor in step (1) is heated to 75-85 DEG C, and adds glycerol, hyaluronic acid and go
Ionized water is stirred, and stirs 10-12min；
(3), after being cooled to 45-50 DEG C, add preservative, i.e. obtain after stirring.
A kind of cosmetic water with white-skinned face function, described cosmetic water is prepared into through said method by above-mentioned raw materials
Arrive.
Compared with prior art, beneficial effects of the present invention:
Various raw medicinal materials used by the present invention are and meet country or Chinese crude drug that provincial standard specifies.This
There is the Chinese medicine composition of white-skinned face function, according to tcm theory, in conjunction with clinical practice, from the traditional Chinese medical science described in bright
Medical material treasure-house filters out the Radix Aucklandiae, Fructus Phyllanthi, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Coptidis, Fructus Forsythiae, Fructus Hippophae and the Pseudobulbus Bletillae (Rhizoma Bletillae) eight taste
Pure purification of tcm forms, and regulates the weight of each raw material, makes to play between each raw material Synergistic
Effect, it is possible to promote that in skin, the blood of blood capillary follows bad, to improve skin nutrition supply, strengthens skin
Elasticity, reduces Keratoderma and pigmentation, reaches the purpose of whitening effect.
Accompanying drawing explanation
Fig. 1 is that the Chinese medicine composition of the present invention is to tyrosinase inhibition test result figure.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But should be by
This is interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to below example, all real based on present invention institute
Existing technology belongs to the scope of the present invention.
Embodiment 1
There is described in the present embodiment the Chinese medicine composition of white-skinned face function, be made up of the raw material of following weight: the Radix Aucklandiae
12g, Fructus Phyllanthi 9g, Radix Glycyrrhizae 9g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Coptidis 6g, Fructus Forsythiae 6g, Fructus Hippophae 6g and Pseudobulbus Bletillae (Rhizoma Bletillae) 3g.
Above-mentioned Chinese medicine composition to prepare extract method as follows: the raw material of above-mentioned weight is added respectively
Enter 75% ethanol of 9 times of volumes, 55 DEG C of reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h,
Filter, merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, obtain work
Property extract.
There is the skin care cosmetic compositions of white-skinned face function, former by following mass percent described in the present embodiment
Material is made: Chinese medicine extract 10%, hyaluronic acid 0.02%, guar hydroxypropyltrimonium chloride 3%,
Glycerol 3%, preservative 0.02%, surplus is deionized water.
The preparation method of above-mentioned skin care cosmetic compositions, comprises the following steps:
(1) Chinese medicine extract, guar hydroxypropyltrimonium chloride are uniformly mixed 10min at 70 DEG C,
At 70 DEG C, put 25min afterwards, form mixed liquor；
(2) mixed liquor in step (1) is heated to 80 DEG C, and adds glycerol, hyaluronic acid and deionization
Water is stirred, and stirs 10min；
(3), after being cooled to 45 DEG C, add preservative, i.e. obtain after stirring.
Embodiment 2
There is described in the present embodiment the Chinese medicine composition of white-skinned face function, be made up of the raw material of following weight: the Radix Aucklandiae
3g, Fructus Phyllanthi 18g, Radix Glycyrrhizae 2g, Rhizoma Atractylodis Macrocephalae 5g, Rhizoma Coptidis 10g, Fructus Forsythiae 1g, Fructus Hippophae 2g and Pseudobulbus Bletillae (Rhizoma Bletillae) 1g.
Above-mentioned Chinese medicine composition to prepare extract method as follows: the raw material of above-mentioned weight is added respectively
Enter 75% ethanol of 10 times of volumes, 55 DEG C of reflux, extract, three times, extraction time be respectively 2.0h, 1.5h,
1.5h, filters, and merges 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, is dried,
Obtain activity extract.
The present embodiment preparation has raw material dosage and the same embodiment of preparation process of the skin protection cosmetics of white-skinned face function
1
Embodiment 3
There is described in the present embodiment the Chinese medicine composition of white-skinned face function, be made up of the raw material of following weight: the Radix Aucklandiae
24g, Fructus Phyllanthi 1g, Radix Glycyrrhizae 16g, Rhizoma Atractylodis Macrocephalae 22g, Rhizoma Coptidis 3g, Fructus Forsythiae 15g, Fructus Hippophae 18g and Pseudobulbus Bletillae (Rhizoma Bletillae) 19g.
Above-mentioned Chinese medicine composition to prepare extract method as follows: the raw material of above-mentioned weight is added respectively
Enter 75% ethanol of 9 times of volumes, 55 DEG C of reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h,
Filter, merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, obtain work
Property extract.
The present embodiment preparation has raw material dosage and the same embodiment of preparation process of the skin protection cosmetics of white-skinned face function
1
Embodiment 4
There is described in the present embodiment the Chinese medicine composition of white-skinned face function, be made up of the raw material of following weight: the Radix Aucklandiae
20g, Fructus Phyllanthi 12g, Radix Glycyrrhizae 10g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Coptidis 8g, Fructus Forsythiae 7g, Fructus Hippophae 10g and Pseudobulbus Bletillae (Rhizoma Bletillae) 6g.
Above-mentioned Chinese medicine composition to prepare extract method as follows: the raw material of above-mentioned weight is added respectively
Enter 75% ethanol of 10 times of volumes, 55 DEG C of reflux, extract, three times, extraction time be respectively 2.0h, 1.5h,
1.5h, filters, and merges 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, is dried,
Obtain activity extract.
The present embodiment preparation has raw material dosage and the same embodiment of preparation process of the skin protection cosmetics of white-skinned face function
1
Comparative example 1
There is described in the present embodiment the Chinese medicine composition of white-skinned face function, be made up of the raw material of following weight: emblic
Sub-9g, Radix Glycyrrhizae 9g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Coptidis 6g, Fructus Forsythiae 6g, Fructus Hippophae 6g and Pseudobulbus Bletillae (Rhizoma Bletillae) 3g.
Above-mentioned Chinese medicine composition to prepare extract method as follows: the raw material of above-mentioned weight is added respectively
Enter 75% ethanol of 9 times of volumes, 55 DEG C of reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h,
Filter, merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, obtain work
Property extract.
The present embodiment preparation has raw material dosage and the same embodiment of preparation process of the skin protection cosmetics of white-skinned face function
1
Comparative example 2
There is described in the present embodiment the Chinese medicine composition of white-skinned face function, be made up of the raw material of following weight: Radix Glycyrrhizae
9g, Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Coptidis 6g, Fructus Forsythiae 6g, Fructus Hippophae 6g and Pseudobulbus Bletillae (Rhizoma Bletillae) 3g.
Above-mentioned Chinese medicine composition to prepare extract method as follows: the raw material of above-mentioned weight is added respectively
Enter 75% ethanol of 9 times of volumes, 55 DEG C of reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h,
Filter, merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, obtain work
Property extract.
The present embodiment preparation has raw material dosage and the same embodiment of preparation process of the skin protection cosmetics of white-skinned face function
1
Test example 1 suppresses tyrosinase activity to test
(1) material
1. solution preparation
(1) PBS solution (pH=6.8,0.1mol/L): 1. 17.91g disodium hydrogen phosphate is dissolved in deionization
In water, it is settled to 500ml with deionized water.2. 7.8g sodium dihydrogen phosphate dihydrate is dissolved in deionized water, spends
Ionized water is settled to 500ml.Take 92.6ml the most respectively and be 1. 2. configured to the phosphorus of 200ml pH=6.8 with 107.4ml
Acid buffering solution.
(2) TYR solution: 0.05g TYR is dissolved in the HCl of 35ml0.1mol/L, uses pH6.8
PBS (0.1mol/L) buffer be settled to 100mL.
(3) tryrosinase: enzyme is lived as 100U/ml.
2. sample preparation
The traditional Chinese medicine composition extract liquid of embodiment 1 deionized water is diluted, be made into concentration be 0.05%, 0.1%,
0.2%, the sample solution of 0.4%, 0.8%, carries out testing below.
(2) test method
1. it is loaded according to table 1, is not added with tryrosinase.
Table 1 tyrosinase inhibition test preparation table
2. solution is placed in constant temperature 10min in 37 DEG C of water-baths.
3. add tryrosinase, solution is placed in 37 DEG C of water-baths after constant temperature 10min, measure under 475nm
Its absorbance, and compare with arbutin.
Inhibitory activity against tyrosinase calculates according to formula (1):
Inhibitory activity against tyrosinase=(Blank absorbance values-sample absorbance value)/Blank absorbance values × 100
(1)
(3) experimental result
Experimental result is shown in accompanying drawing 1.Embodiment 1 Chinese medicine composition extract, just shows 0.05% in concentration
Tyrosinase inhibitory activity, is 44% to inhibitory activity against tyrosinase；When concentration reaches 0.2%, to cheese
Propylhomoserin inhibition of enzyme activity rate reaches more than 90%.
Clinical trial example
Clinical 240 example female volunteers are tested, age distribution scope be 16-50 year, be divided into 6 groups,
Use above-mentioned prepared skin protection cosmetics respectively, smear in cervical region and face, be massaged into gently and absorb, often
People is the most each once for every day, according to therapeutic effect, uses February and observes, and by following criterion of therapeutical effect
Determine using effect.
Recovery from illness: patient skin colour of skin phenomenon irregular, dark yellow is wholly absent.
Effective: the patient skin colour of skin is irregular, dark yellow phenomenon has been alleviated.
Invalid: before and after patient's use, symptom is without improving.
Through clinical usage, 160 example examinations of the Chinese medicine composition with white-skinned face function that prepared by above-described embodiment 1-4
Testing in example, effective example is 136 examples, accounting 85%, and recovery from illness example is 112 examples, accounting 70%.
And in the 80 example test examples of the Chinese medicine composition with white-skinned face function prepared of above-mentioned comparative example 1-2, have
Effect example is 48 examples, and accounting is only 60%, and recovery from illness example is 24 examples, and accounting is only 30%.Without patient, skin occurs
Skin discomfort and other side effect.
Claims (10)
1. a Chinese medicine composition with white-skinned face function, it is characterised in that described compositions is joined by following weight portion
The crude drug of ratio is made: the Radix Aucklandiae 3～24 parts, Fructus Phyllanthi 1～18 parts, Radix Glycyrrhizae 2～16 parts, the Rhizoma Atractylodis Macrocephalae 1～22 parts,
Rhizoma Coptidis 3～10 parts, Fructus Forsythiae 1～15 parts, Fructus Hippophae 2～20 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1～9 parts.
A kind of Chinese medicine composition with white-skinned face function the most according to claim 1, it is characterised in that described
Compositions is made up of the crude drug of following weight: the Radix Aucklandiae 5～20 parts, Fructus Phyllanthi 3～15 parts, Radix Glycyrrhizae
2～15 parts, the Rhizoma Atractylodis Macrocephalae 1～18 parts, Rhizoma Coptidis 3～7 parts, Fructus Forsythiae 2～12 parts, Fructus Hippophae 2～14 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1～6
Part.
A kind of Chinese medicine composition with white-skinned face function the most according to claim 2, it is characterised in that described
Compositions is made up of the raw material of following weight proportion: the Radix Aucklandiae 10～15 parts, Fructus Phyllanthi 5～10 parts, Radix Glycyrrhizae 5～12
Part, the Rhizoma Atractylodis Macrocephalae 2～9 parts, Rhizoma Coptidis 3～6 parts, Fructus Forsythiae 4～8 parts, Fructus Hippophae 3～10 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1～5 parts.
A kind of Chinese medicine composition with white-skinned face function the most according to claim 3, it is characterised in that described
Compositions is made up of the raw material of following weight proportion: the Radix Aucklandiae 12 parts, Fructus Phyllanthi 9 parts, 9 parts of Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae
6 parts, Rhizoma Coptidis 6 parts, Fructus Forsythiae 6 parts, Fructus Hippophae 6 parts and the Pseudobulbus Bletillae (Rhizoma Bletillae) 3 parts.
5. a Chinese medicine extract with white-skinned face function, it is characterised in that described extract is by claim 1-4
Compositions described in any one is extracted through Chinese materia medica general extraction methods and is obtained.
6. the application in preparing skin protection cosmetics of the Chinese medicine extract described in claim 5.
7. the Chinese medicine composition described in a claim 1 prepare extract method, it is characterised in that specifically walk
Rapid as follows:
(1) each crude drug is weighed according to the proportioning of any one of claim 1-4；
(2) described crude drug is separately added into 75% ethanol of 8～10 times of volumes, 55 DEG C of reflux, extract, three times, extract
Time is respectively 2.0h, 1.5h, 1.5h, filters, merges 3 filtrates；
(3) by described filtrate recycling ethanol and concentrate, then by the concentrated solution mix homogeneously of each crude drug, it is dried,
To activity extract.
8. a skin care cosmetic compositions with white-skinned face function, it is characterised in that described skin protection cosmetics combines
Thing is made up of the raw material of following mass percent:
Described Chinese medicine extract is extract described in claim 5 or the Chinese medicine extract of claim 7 preparation.
9. the method preparing skin care cosmetic compositions described in claim 8, it is characterised in that described specifically
Step is as follows:
(1) Chinese medicine extract, guar hydroxypropyltrimonium chloride are uniformly mixed 5-15min at 65-75 DEG C,
At 65-75 DEG C, put 20-30min afterwards, form mixed liquor；
(2) mixed liquor in step (1) is heated to 75-85 DEG C, and adds glycerol, hyaluronic acid and deionization
Water is stirred, and stirs 10-12min；
(3), after being cooled to 45-50 DEG C, add preservative, i.e. obtain after stirring.
10. a cosmetic water with white-skinned face function, it is characterised in that described cosmetic water is by described in claim 8
Raw material prepare through method described in claim 9.
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Application publication date: 20160817 |