CN105832927A - Chinese patent medicine for clearing away heat, dispelling wind, alleviating pain and removing nebula and preparation process of Chinese patent medicine - Google Patents
Chinese patent medicine for clearing away heat, dispelling wind, alleviating pain and removing nebula and preparation process of Chinese patent medicine Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/51—Gentianaceae (Gentian family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/718—Coptis (goldthread)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a Chinese patent medicine for clearing away heat, dispelling wind, alleviating pain and removing nebula and a preparation process of Chinese patent medicine. The Chinese patent medicine for replenishing Qi and nourishing blood is prepared from the following Chinese medicinal materials in parts by weight: 40 to 100 parts of rhizoma rehmanniae, 40 to 100 parts of radix angelicae sinensis, 40 to 100 parts of fructus gardenia, 40 to 100 parts of chrysanthemum, 40 to 100 parts of cassia seeds, 40 to 100 parts of radix bupleuri, 40 to 100 parts of radix saposhnikoviae, 40 to 100 parts of radix scutellariae, 40 to 100 parts of radix gentianae, 40 to 100 parts of salted rhizoma alismatis, 40 to 100 parts of herba equiseti hiemalis, 40 to 100 parts of rhizoma coptidis, 1 to 6 parts of menthol, 1 to 10 parts of borneol and 1 to 2 parts of bear gall powder. The Chinese patent medicine for clearing away the heat, dispelling the wind, alleviating the pain and removing the nebula is reasonable in formula, fewer but exquisite in medicinal materials, synergistic in various medicines and capable of achieving an effect of replenishing Qi and nourishing the blood.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing and preparation technology thereof.
Background technology
Heat clearing away refers to remove pathogenic heat or the various method for the treatment of of deficiency-heat.The commonly referred to as excess-heat caused by diseases caused by exogenous pathogenic factor pathogenic warmth.Evil preferably use clearing heat with pungent and cool-natured drugs at edema caused by disorder of QI;Excessive noxious heat or press from both sides and wet preferably use clearing up internal heat by using drugs of bitter in taste and cold in nature;Intenseness of heat impairment of body fluid preferably use clearing away heat with drugs sweet in flavor and cold in nature;Heat preferably uses heat clearing and blood cooling method etc. in nutrient blood.The interior-heat raw by the deficiency of YIN, referred to as deficiency-heat, preferably use yin nourishing with heat clearing away.Yin nourishing has nourishing lung yin. liver-yin. and kidney yin and nourishing blood. grow the multiple methods such as liquid, must fit applications as the case may be.In the consumption of YIN caused by febrile disease stage, it is possible to refer and synthesize Yin-enching and Heat-cleaning.The heating separately having the deficiency of vital energy and cause, preferably uses sweet temperature gas supplementing medicine to treat, does not belong to heat clearing away scope;
Dissipate wind with regard to wind dispelling. refer to that common wind and cold, wind heat, rheumatism three kinds hold the disease of ailment said due to cold or exposure under the arm;
Nebula removing refers to eliminate the fuzzy foreign body curled up around eyes.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation safely, effectively, having no side effect.
It is a further object to provide a kind of clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing and preparation technology thereof.
To achieve these goals, the present invention, according to theory of Chinese medical science, sums up clinical experience composition effective formula and drug for many years.
Its prescription is as follows:
Radix Rehmanniae 40~100 parts, Radix Angelicae Sinensis 40~100 parts, Fructus Gardeniae 40~100 parts, Flos Chrysanthemi 40~100 parts, Semen Cassiae 40~100 parts, Radix Bupleuri 40~100 parts, Radix Saposhnikoviae 40~100 parts, Radix Scutellariae 40~100 parts, Radix Gentianae 40~100 parts, Rhizoma Alismatis (processeded with salt) 40~100 parts, Herba Equiseti Hiemalis 40~100 parts, Rhizoma Coptidis 40~100 parts, Mentholum 1~6 parts, Borneolum Syntheticum 1~10 parts, Fel Ursi powder 1~2 parts.
The invention has the beneficial effects as follows:
1, the prescription of the present invention is compared with the prescription for the treatment of similar disease at present, reasonable recipe, and flavour of a drug are fewer but better, and each medicine produces synergism, can produce good clearing away heat to dispel wind, pain relieving nebula removing effect.
2, the preparation process research design of the present invention is careful rationally, pharmacodynamics is combined with active component and has formulated extraction process, at good clearing away heat to dispel wind, impurity is farthest removed on the basis of pain relieving nebula removing, ensure that the drug effect of prescription, reducing again injection volume, the Study on Forming for preparation is laid a good foundation.
3, the present invention is clearing away heat to dispel wind, and pain relieving nebula removing Chinese patent medicine can also make dosage form series, including capsule, tablet, granule, soft capsule or other dosage forms etc..These dosage forms all have the advantages such as easy to use, good stability, quality controllability are good, patient adaptability is good.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, but is not limited thereto.
Embodiment
1
A kind of clearing away heat to dispel wind, pain relieving nebula removing Chinese patent medicine, it is made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 60 parts, Radix Angelicae Sinensis 60 parts, Fructus Gardeniae 60 parts, Flos Chrysanthemi 60 parts, Semen Cassiae 60 parts, Radix Bupleuri 60 parts, Radix Saposhnikoviae 60 parts, Radix Scutellariae 60 parts, Radix Gentianae 100 parts, Rhizoma Alismatis (processeded with salt) 60 parts, Herba Equiseti Hiemalis 60 parts, Rhizoma Coptidis 60 parts, Mentholum 6 parts, Borneolum Syntheticum 8 parts, Fel Ursi powder 2 parts.
Embodiment
2
A kind of clearing away heat to dispel wind, pain relieving nebula removing Chinese patent medicine, it is made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 70 parts, Radix Angelicae Sinensis 70 parts, Fructus Gardeniae 70 parts, Flos Chrysanthemi 70 parts, Semen Cassiae 70 parts, Radix Bupleuri 70 parts, Radix Saposhnikoviae 70 parts, Radix Scutellariae 70 parts, Radix Gentianae 100 parts, Rhizoma Alismatis (processeded with salt) 70 parts, Herba Equiseti Hiemalis 70 parts, Rhizoma Coptidis 70 parts, Mentholum 6 parts, Borneolum Syntheticum 8 parts, Fel Ursi powder 2 parts.
Embodiment
3
A kind of clearing away heat to dispel wind, pain relieving nebula removing Chinese patent medicine, it is made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 60 parts, Radix Angelicae Sinensis 60 parts, Fructus Gardeniae 60 parts, Flos Chrysanthemi 80 parts, Semen Cassiae 80 parts, Radix Bupleuri 80 parts, Radix Saposhnikoviae 80 parts, Radix Scutellariae 80 parts, Radix Gentianae 100 parts, Rhizoma Alismatis (processeded with salt) 80 parts, Herba Equiseti Hiemalis 80 parts, Rhizoma Coptidis 80 parts, Mentholum 6 parts, Borneolum Syntheticum 1~8 parts, Fel Ursi powder 2 parts.
Embodiment
4
A kind of clearing away heat to dispel wind, pain relieving nebula removing Chinese patent medicine, it is made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 50 parts, Radix Angelicae Sinensis 50 parts, Fructus Gardeniae 50 parts, Flos Chrysanthemi 50 parts, Semen Cassiae 70 parts, Radix Bupleuri 70 parts, Radix Saposhnikoviae 70 parts, Radix Scutellariae 70 parts, Radix Gentianae 100 parts, Rhizoma Alismatis (processeded with salt) 80 parts, Herba Equiseti Hiemalis 80 parts, Rhizoma Coptidis 80 parts, Mentholum 6 parts, Borneolum Syntheticum 1~8 parts, Fel Ursi powder 2 parts.
Embodiment
5
A kind of clearing away heat to dispel wind, the preparation of pain relieving nebula removing capsule
The Chinese patent medicine of embodiment 1~4 can be made a kind of clearing away heat to dispel wind, pain relieving nebula removing capsule by following technique, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis are ground into fine powder respectively, sieve;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, dry, pulverize after making fine powder standby;
(4) fine powder in (2) and (3) is merged, mixing, add 1% magnesium stearate, 1% silicon dioxide mixing, fill capsule, make clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing.
Using method: oral.
Embodiment
6
One
Plant clearing away heat to dispel wind, the preparation of pain relieving nebula removing sheet
The Chinese patent medicine of embodiment 1~4 can be made a kind of clearing away heat to dispel wind, pain relieving nebula removing sheet by following technique, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis are ground into fine powder respectively, sieve;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, dry, pulverize after making fine powder standby;
(4) merge the fine powder in (2) and (3), add 1% magnesium stearate, 1% silicon dioxide mixing, tabletting, make the Chinese patent medicine of benefiting qi and nourishing blood.
Using method: oral.
Embodiment
7
One
Plant clearing away heat to dispel wind, the preparation that pain relieving nebula removing dissipates
By following technique, the Chinese patent medicine of embodiment 1~4 can be made a kind of clearing away heat to dispel wind, pain relieving nebula removing dissipates, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis are ground into fine powder respectively, sieve;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, dry, pulverize after making fine powder standby;
(4) merge the fine powder in (2) and (3), mix homogeneously, add 1% silicon dioxide mixing, pack, make clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing.
Using method: warm water is taken after mixing it with water.
Embodiment
8
One
Plant clearing away heat to dispel wind, the preparation of pain relieving nebula removing granule
The Chinese patent medicine of embodiment 1~4 can be made a kind of clearing away heat to dispel wind, pain relieving nebula removing granule by following technique, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis are ground into fine powder respectively, sieve;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, dry, pulverize after making fine powder standby;
(4) merge the fine powder in (2) and (3), mix homogeneously, add 1% magnesium stearate, 1% silicon dioxide mixing, pack, make clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing.
Using method: warm water is taken after mixing it with water.
Embodiment
9
One
Plant clearing away heat to dispel wind, the preparation of pain relieving nebula removing soft capsule
The Chinese patent medicine of embodiment 1~4 can be made a kind of clearing away heat to dispel wind, pain relieving nebula removing soft capsule by following technique, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis are ground into fine powder respectively, sieve;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, dry, pulverize after making fine powder standby;
(4) merge the fine powder in (2) and (3), mix homogeneously, add appropriate soybean oil, mixing, as content, prepare suitable rubber, encapsulating machine is made soft capsule, make clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing.
Using method: warm water is taken after mixing it with water.
Claims (8)
1. one kind is used for clearing away heat to dispel wind, the Chinese patent medicine of pain relieving nebula removing, it is characterized in that, be mainly made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 40~100 parts, Radix Angelicae Sinensis 40~100 parts, Fructus Gardeniae 40~100 parts, Flos Chrysanthemi 40~100 parts, Semen Cassiae 40~100 parts, Radix Bupleuri 40~100 parts, Radix Saposhnikoviae 40~100 parts, Radix Scutellariae 40~100 parts, Radix Gentianae 40~100 parts, Rhizoma Alismatis (processeded with salt) 40~100 parts, Herba Equiseti Hiemalis 40~100 parts, Rhizoma Coptidis 40~100 parts, Mentholum 1~6 parts, Borneolum Syntheticum 1~10 parts, Fel Ursi powder 1~2 parts, add proper auxiliary materials and make 300 parts after extraction.
Clearing away heat to dispel wind the most according to claim 1, the Chinese patent medicine of pain relieving nebula removing, it is characterised in that, mainly it is made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 50~80 parts, Radix Angelicae Sinensis 50~80 parts, Fructus Gardeniae 50~80 parts, Flos Chrysanthemi 50~80 parts, Semen Cassiae 50~80 parts, Radix Bupleuri 50~80 parts, Radix Saposhnikoviae 50~80 parts, Radix Scutellariae 50~80 parts, Radix Gentianae 50~100 parts, Rhizoma Alismatis (processeded with salt) 50~80 parts, Herba Equiseti Hiemalis 50~80 parts, Rhizoma Coptidis 50~80 parts, Mentholum 1~6 parts, Borneolum Syntheticum 1~8 parts, Fel Ursi powder 1~2 parts.
Clearing away heat to dispel wind the most according to claim 2, the Chinese patent medicine of pain relieving nebula removing, it is characterised in that, mainly it is made up of the Chinese crude drug of following mass parts: Radix Rehmanniae 60 parts, Radix Angelicae Sinensis 60 parts, Fructus Gardeniae 60 parts, Flos Chrysanthemi 60 parts, Semen Cassiae 60 parts, Radix Bupleuri 60 parts, Radix Saposhnikoviae 60 parts, Radix Scutellariae 60 parts, Radix Gentianae 100 parts, Rhizoma Alismatis (processeded with salt) 60 parts, Herba Equiseti Hiemalis 60 parts, Rhizoma Coptidis 60 parts, Mentholum 6 parts, Borneolum Syntheticum 8 parts, Fel Ursi powder 2 parts.
4. according to Chinese patent medicine described in any one of claims 1 to 3, it is characterised in that described Chinese patent medicine also can add the adjuvant pharmaceutically allowed and make oral formulations.
5. the clearing away heat to dispel wind described in any one of Claims 1 to 4, the preparation method of the Chinese patent medicine of pain relieving nebula removing, comprise the steps:
(1) each medicine is weighed in proportion;
(2) Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis are ground into fine powder respectively, sieve;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, dry, pulverize after making fine powder standby;
(4) merge the fine powder in (2) and (3), add appropriate amount of auxiliary materials, make the Chinese patent medicine of benefiting qi and nourishing blood.
Preparation method the most according to claim 5, step (3) is characterized in that, the condition of the soak by water technology of employing is: adds 8~10 times of water, soaks 0.5~1h.
Preparation method the most according to claim 5, it is characterised in that the technical conditions of step (3) described decocting cooking method are: decoct 2 hours for the first time, second time decocts 1 hour, filters, merging filtrate, concentrates, and is dried, and prepares extract powder.
Preparation method the most according to claim 5, it is characterized in that, the concrete operations of step (4) are: select lactose or sucrose, uniform with medicament mixed such as extract extract powder, Fel Ursi powder, Mentholum, Borneolum Syntheticum, Rhizoma Coptidis powder, again through different process, make the clearing away heat to dispel wind of different dosage form, the Chinese patent medicine of pain relieving nebula removing.
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CN106266331A (en) * | 2016-09-27 | 2017-01-04 | 成都市飞龙水处理技术研究所 | A kind of treat wind heat or the Chinese medicine composition of conjunctival congestion and swelling pain that dampness-heat of the liver causes |
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CN103751307A (en) * | 2014-01-09 | 2014-04-30 | 广东药学院 | External pain-relieving Chinese patent medicine and preparation process thereof |
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CN106266331A (en) * | 2016-09-27 | 2017-01-04 | 成都市飞龙水处理技术研究所 | A kind of treat wind heat or the Chinese medicine composition of conjunctival congestion and swelling pain that dampness-heat of the liver causes |
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