CN1058174C - Medicine for coronary heart disease and production thereof - Google Patents
Medicine for coronary heart disease and production thereof Download PDFInfo
- Publication number
- CN1058174C CN1058174C CN96121454A CN96121454A CN1058174C CN 1058174 C CN1058174 C CN 1058174C CN 96121454 A CN96121454 A CN 96121454A CN 96121454 A CN96121454 A CN 96121454A CN 1058174 C CN1058174 C CN 1058174C
- Authority
- CN
- China
- Prior art keywords
- medicine
- parts
- cinnabaris
- heart disease
- coronary heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to medicine for treating coronary diseases and a production method of the medicine. The medicine contains acanthopanax flower, immature fruit, pleuropterus cordatus, red sage root, corydalis tuber and cinnabar. The present invention can be processed into powder preparation, granular preparation and tablet preparation, and has a simple production method. The medicine is used for treating diseases such as myocardial ischemia, angina pectoris, arrhythmia, myocardial infarction and myocardial sclerosis, and the diseases are caused by stenosis and blockage resulting from coronary atherosclerosis. The medicine has the advantages of easy use, short course of treatment, obvious effect, and no toxicity or side effect for long-term administration. An effective rate is more than 90%, and a recovery rate is more than 70%.
Description
The present invention relates to a kind of medicine and production method thereof for the treatment of coronary heart disease.
At present, the medicine of treatment coronary heart disease mostly is Western medicine greatly, generally temporary transient disease controlling, can not thoroughly treat,, enter heart coronary artery by hypoglossis mucous membrane cell Transdermal absorption as using more general Nitroglycerin Sublingual clinically, the diastole arteria coronaria increases the confession of arteria coronaria blood, allevating angina pectoris, because of its metabolism fast, can't take for a long time, and liver first-pass effect is arranged, so can only when angina pectoris attacks, just use, very inconvenient, and can not adopt oral way; And general Chinese herbal medicine, Time of Administration is long, and therapeutic effect is not obvious.
List of references is:
1. Pharmacopoeia of the People's Republic of China nineteen ninety-five version,
Ministry of Health of the People's Republic of China's committee of pharmacopeia is compiled,
Guangdong science and technology publishing house publishes;
2. " Pharmacopoeia of People's Republic of China Chinese medicine colored atlas " nineteen ninety-five version,
Ministry of Health of the People's Republic of China's committee of pharmacopeia is compiled,
Guangdong science and technology publishing house publishes;
3. " Chinese medicine voluminous dictionary " in October, 1991 version,
The new medical college in Jiangsu is compiled,
Shanghai science tech publishing house publishes;
4. Compendium of Material Medica in November, 1992 version
Bright. Li Shizhen (1518-1593 A.D.) is write,
The People's Health Publisher publishes;
5. " practical coronary heart disease " June in 1981 1 edition,
Zhang Hong repaiies Shi Yushu and compiles,
Tianjin science tech publishing house publishes;
6. " clinical crown cardiology " April in 1994 1 edition,
Chen Zaijia Xu Yi pivot is compiled,
The People's Medical Officer Press publishes;
7. " national distinguished veteran doctors of TCM proved recipe selected works " October in 1989 1 edition,
Wei is waved moral Wang Zhenhai chief editor,
Science books and periodicals publishing house publishes.
Purpose of the present invention just is to overcome the disease controlling temporarily of Western medicine of medicine of present treatment coronary heart disease and the unconspicuous shortcoming of therapeutic effect of Chinese herbal medicine, and a kind of oral Chinese herbal medicine and production method thereof of treatment coronary heart disease of thorough disease controlling is provided.
The present invention realizes like this.
Adopting manyprickle acanthopanax petal and immature fruit is principal agent, also can be equipped with other medicines, makes powder or other peroral dosage form, as electuary, and Chinese herbal medicine tablet etc.Immature fruit is the fruit of the green of firm knot, adopts manyprickle acanthopanax petal and immature fruit, and is standby after drying.
Medicine of the present invention is manyprickle acanthopanax petal and immature fruit, Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Cinnabaris.
The ratio of its medicine is (weight portion): 800～1200 parts of manyprickle acanthopanax petal and immature fruits, 80～120 parts of Radix Polygoni Multiflori, 80～120 parts of Radix Salviae Miltiorrhizaes, 30～60 parts of Rhizoma Corydalis, 10～25 parts in Cinnabaris.
The optimal proportion of medicine is (weight portion): 1000 parts of manyprickle acanthopanax petal and immature fruits, 100 parts of Radix Polygoni Multiflori, 100 parts of Radix Salviae Miltiorrhizaes, 50 parts of Rhizoma Corydalis, 20 parts in Cinnabaris.
Medicine of the present invention can be beaten powder and make powder, also can after water is carried, add adjuvant and make electuary, tablet etc., dosage be 10 the gram medicines/time, every day three times, when half flesh is half-full, early, middle and late servicing once.Period in a medicine is avoided zest things such as Radix Raphani, Fructus Lycopersici esculenti, Fructus Capsici, cigarette, wine.
The preparation method of each raw material is:
(1) gather manyprickle acanthopanax petal and immature fruit clean dry standby.
(2) He Daowu removes stem and leaf to clean and is cut to sheet, adds Semen sojae atricolor and steams that to dry into black standby.
(3) it is standby that Radix Salviae Miltiorrhizae cuts off stem, leaf must go clean silt to dry.
(4) Cinnabaris is washed in a pan and is removed silt, inhales with Magnetitum and removes ferrous contaminants, and porphyrize water flies to dry standby.
(5) Rhizoma Corydalis is removed fibrous root and is cleaned to put into to pull out when boiling the white point that the grain of rice is arranged to inner flavescence, center in the boiling water and dry wine again and fry.
The method for preparing powder is: with the broken sieving to obtain fine powder of each medicated powder, again medicated powder sterilized 1.5 hours down in 1.5 atmospheric pressure, and aseptic subpackaged, be sealed to 10 gram medicated powder/bags.Keep in Dark Place.
The method that is prepared into other preparation is for except that Cinnabaris, and each medicine is carried through water, concentrates, and adds adjuvant, Cinnabaris is granulated into electuary, or further adds additive of tablet and strike out tablet.
The applicant suffers from coronary heart disease, selects for use multiple medicine and traditional therapy all undesirable at first, and the back adopts Radix Acanthopanacis Senticosi root, stem treatment that curative effect has been arranged, but still not obvious.Through reading up the literature, do not see that document is relevant for spending the medicinal of seed.The applicant promptly obeyed the bud that Radix Et Caulis Acanthopanacis Senticosi has just been sent out in spring afterwards, obey Cortex Acanthopanacis Radicis summer, obey the Radix Et Caulis Acanthopanacis Senticosi rhizome autumn, obey Folium Acanthopanacis Senticosi winter, effective with sharp bud effect beguine, stem, skin, the leaf that just sent out spring, then pluck manyprickle acanthopanax petal and just the green immature fruit of knot dry, it is fine to take effect, take better effects if after concoct compatibility.
Narrow to due to the coronary atherosclerosis of year clinical practice surplus the applicant ten, the medicine that shows treatment coronary heart disease of the present invention, the angina pectoris that the myocardial ischemia that obturation causes causes, arrhythmia, disease such as myocardial infarction, myocardiosclerosis is effective, takes for a long time to have no side effect untoward reaction.Easy to use, short treating period, general 4～7 beginning onsets, curative effect is fast, and total effective rate reaches more than 90%, cure rate about 70%.
The invention will be further described below in conjunction with embodiment.
Embodiment 1, gets manyprickle acanthopanax petal and immature fruit, dries.Through pulverizing, make 10 gram/bags.
Embodiment 2, get 1000 parts of manyprickle acanthopanax petal and immature fruits, 100 parts of Radix Polygoni Multiflori, 100 parts of Radix Salviae Miltiorrhizaes, 50 parts of Rhizoma Corydalis, 20 parts in Cinnabaris.
Make powder by the preparation method of above-mentioned each raw material and the preparation method of powder.
Embodiment 3, and medicine is processed into electuary with embodiment 2 with medicine.
Embodiment 4, and medicine is processed into tablet with embodiment 2 with medicine.
Embodiment 5, get 1000 parts of manyprickle acanthopanax petal and immature fruits, 80 parts of Radix Polygoni Multiflori, 80 parts of Radix Salviae Miltiorrhizaes, 30 parts of Rhizoma Corydalis, 10 parts in Cinnabaris.Make electuary.
Embodiment 6, get 800 parts of manyprickle acanthopanax petal and immature fruits, 120 parts of Radix Polygoni Multiflori, 120 parts of Radix Salviae Miltiorrhizaes, 60 parts of Rhizoma Corydalis, and 25 parts in Cinnabaris is made tablet.
Embodiment 7, get 1200 parts of manyprickle acanthopanax petal and immature fruits, 100 parts of Radix Polygoni Multiflori, 80 parts of Radix Salviae Miltiorrhizaes, 60 parts of Rhizoma Corydalis, and 20 parts in Cinnabaris is made powder.
Adopt embodiments of the invention 2, patients with coronary heart disease is treated, it is as follows to take passages some cases now:
1. grandson *, man, 37 years old;
89 years, dyspnea stuffy, constriction is arranged, 2 years because of ambition.
Through Fushun City's hospital diagnosis: coronary heart disease, arrhythmia, myocardiosclerosis, the treatment commentaries on classics of not getting better in 3 months of having a rest of being in hospital.After the people makes referrals to after here treated for 1 week, the heart is vexed obviously to be alleviated, following ground is movable breathe obviously improve, sleep increases, movable health is strong.Take medicine 2 months fundamental symptomss disappear, and do not have uncomfortable sensation, energetic, recovery from illness after 4 months.This medicine one of clothes is continued in the back does not have the effect of paying, not recurrence so far.
2. thunder * *, the man 63 years old, went bald and rheumatism both legs knee arthritis, difficulty in walking, hypopnea, giddy, angina pectoris, about 3 years in 27 years old.Through Fushun City's hospital diagnosis is coronary heart disease and arthritis.Disappear with loose 2 months subjective symptomss of clothes and arthritis of this medicine, continued clothes 2 years, bald tissue regeneration promoting hair.
3. Xing * *, man 59 years old;
Be diagnosed as coronary heart disease because of nauseating, uncomfortable in chest, heart beating, the unable treatment to Fushun City hospital of myocardial infarction, myocardial infarction, chronic coronary artery blood supply insufficiency 55 year old that year.Treat 2 months invalid.The back is treated to take medicine to here and is begun to take effect about 7 days, and subjective symptoms all disappears after 2 months, and feel energy fair abundant, the senile plaque Periostracum Cicadae with face falls on hand, the hair cream hair color is bright, the clothes that continue had no adverse reaction in 1 year, recurs so far.
4. revive * *, the man, 50 years old,
Year hypertension history surplus suffering from 20, the sense chest is close in the time of 89 years, the aroused in interest palpitation with a distress feeling of throbbing with fear, short of breath is felt the preceding angor of the heart suddenly and is takeed on the arm radiation left, and several minutes beginnings were alleviated.ECG ST-T changes.The slight strain of cardiac muscle, X line rabat shows that heart generally increases, be diagnosed as coronary heart disease, take 3 days chest pain cardiopalmus of this medicine and pause and remove, after 7 days, the ultrasoundcardiogram check, except that mitral incompetence, companion's prolapsus, left ventricle load increase, surplus no abnormality seen, 2 first quarter moons of continuation this medicine of clothes, above-mentioned symptom all disappears, and blood pressure is normal, does not see higher.
5. poplar * *, woman, 52 years old;
Pareordia twinge in 91 years outbreak repeatedly in 1 year, shoulder and bottleneck throat diffuse left bitterly, companion's cardiopalmus, breathe hard, perspire, dizziness, insomnia, Western medicine diagnose be angina pectoris, treated 5 days produce effects of this medicine of clothes on February 18th, 93 to here, 2 months stable disease, above-mentioned symptom all disappeared in 3 months, so far not recurrence.
Other embodiments of the invention curative effect is close with embodiment 2, the invention is not restricted to the foregoing description.
Claims (3)
1. a medicine for the treatment of coronary heart disease is characterized in that it being to be made by the following raw materials by weight proportions thing: 800～1200 parts of manyprickle acanthopanax petal and immature fruits, 80～120 parts of Radix Polygoni Multiflori, 80～120 parts of Radix Salviae Miltiorrhizaes, 30～60 parts of Rhizoma Corydalis, 10～25 parts in Cinnabaris.
2. a kind of medicine for the treatment of coronary heart disease according to claim 1, the ratio that it is characterized in that material medicine are 1000 parts of manyprickle acanthopanax petal and immature fruits, 100 parts of Radix Polygoni Multiflori, 100 parts of Radix Salviae Miltiorrhizaes, 50 parts of Rhizoma Corydalis, 20 parts in Cinnabaris.
3. the medicine production method of a treatment coronary heart disease as claimed in claim 1 is characterized in that being prepared as of each raw material:
(1) gather manyprickle acanthopanax petal and immature fruit clean dry standby;
(2) Radix Polygoni Multiflori removes stem and leaf to clean and is cut to sheet, adds Semen sojae atricolor and steams that to dry into black standby;
(3) Radix Salviae Miltiorrhizae cuts off stem, leaf, must to go clean silt to dry standby;
(4) Cinnabaris is washed in a pan and is removed silt, inhales with Magnetitum and removes ferrous contaminants, and porphyrize water flies to dry standby;
(5) Rhizoma Corydalis is removed fibrous root and is cleaned to put into to pull out when boiling the white point that the grain of rice is arranged to inner flavescence, center in the boiling water and dry wine again and fry;
The method for preparing powder is: above-mentioned each medicine is crushed and screened into fine powder in proportion, again medicamental pulverata sterilized 1.5 hours down in 15 atmospheric pressure, and aseptic subpackaged, be sealed to 10 gram medicated powder/bags;
The method for preparing electuary is: except that Cinnabaris, above-mentioned each medicine is carried through water, concentrates, and interpolation adjuvant, Cinnabaris are granulated into electuary;
The method for preparing tablet is: the electuary after granulating, further add additive of tablet and strike out tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96121454A CN1058174C (en) | 1996-12-24 | 1996-12-24 | Medicine for coronary heart disease and production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96121454A CN1058174C (en) | 1996-12-24 | 1996-12-24 | Medicine for coronary heart disease and production thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1185963A CN1185963A (en) | 1998-07-01 |
| CN1058174C true CN1058174C (en) | 2000-11-08 |
Family
ID=5126906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96121454A Expired - Fee Related CN1058174C (en) | 1996-12-24 | 1996-12-24 | Medicine for coronary heart disease and production thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1058174C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8486464B2 (en) * | 2000-12-22 | 2013-07-16 | Tasly Pharmaceutical Group Co. Ltd. | Herbal composition for angina pectoris, method to prepare same and uses thereof |
| US20050037094A1 (en) | 2003-07-31 | 2005-02-17 | Xijun Yan | Composition for heart disease, its active ingredients, method to prepare same and uses thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075648A (en) * | 1993-01-06 | 1993-09-01 | 张良华 | Have one's ideas straightened out comfortable production method |
| CN1103302A (en) * | 1993-12-01 | 1995-06-07 | 董兴武 | Hypolipemic and heart tonifying capsule and preparing process thereof |
| CN1113785A (en) * | 1994-07-04 | 1995-12-27 | 宋士岳 | Acanthopanax root injection freeze-dried powder injection and producing technology for acanthopanax root extract |
-
1996
- 1996-12-24 CN CN96121454A patent/CN1058174C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075648A (en) * | 1993-01-06 | 1993-09-01 | 张良华 | Have one's ideas straightened out comfortable production method |
| CN1103302A (en) * | 1993-12-01 | 1995-06-07 | 董兴武 | Hypolipemic and heart tonifying capsule and preparing process thereof |
| CN1113785A (en) * | 1994-07-04 | 1995-12-27 | 宋士岳 | Acanthopanax root injection freeze-dried powder injection and producing technology for acanthopanax root extract |
Non-Patent Citations (3)
| Title |
|---|
| 《中药通报》6(4) 1981.4.30 黄贵生等，治疗冠心病新药救尔心的研究 * |
| 《药学通报》2(10) 1986.10.31 黄政瑞等，刺五加注射液研究初报 * |
| 《药学通报》2(10) 1986.10.31 黄政瑞等，刺五加注射液研究初报;《中药通报》6(4) 1981.4.30 黄贵生等，治疗冠心病新药救尔心的研究 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1185963A (en) | 1998-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1742939A (en) | Medicine for treating pulmonary fibrosis and preparing method | |
| CN103815111B (en) | Health chuzhou chrysanthemum chewing gum and production method thereof | |
| CN1240416C (en) | Medicine for curing hypertension and its preparation method | |
| CN1772194A (en) | Chinese herbal medicine prepn for strengthening kidney-Yang | |
| CN101745078B (en) | Chinese medicinal composition for treating cardiac failure and preparation method thereof | |
| CN1772196A (en) | Heart failure regulating Chinese medicine | |
| CN1628760A (en) | Traditional Chinese medicinal formulation for treating cardiovascular and cerebrovascular disease | |
| CN1733242A (en) | Medicine for curing qi deficiency induced thoracic obstruction (coronary heart disease) and technique for preparing the same | |
| CN1058174C (en) | Medicine for coronary heart disease and production thereof | |
| CN101041006A (en) | Composite Chinese medicine took orally for treating coronary heart disease | |
| CN101049438A (en) | Composition of Chinese traditional medicine for treating coronary heart disease | |
| CN1947791A (en) | External use traditional Chinese medicine ointment for treating heart diseases | |
| CN1211434A (en) | Oral liquid for resisting altitude stress and its preparation method | |
| CN1261131C (en) | Medicinal plaster for treating cervical vertebra disease | |
| CN1245197C (en) | Chinese medicine preparation for treating coronary heart disease and viral myocarditis | |
| CN101637556B (en) | Pharmaceutical composition for treating heart disease and preparation method thereof | |
| CN1227023C (en) | Drug for treating coronary heart disease, angina and preparation method | |
| CN105497701A (en) | Natural medicine for treating gout diseases and preparation method thereof | |
| CN1883529A (en) | A pharmaceutical composition for treating cardiovascular and cerebrovascular disease and preparation method thereof | |
| CN1296830A (en) | Chinese-medicinal capsule for treating diabetes | |
| CN1051935C (en) | Naoxuekang capsule for curing cerebrovascular disease and its production | |
| CN102671033B (en) | Traditional Chinese medicine composition for improving sleep and strengthening organism immunity, and clinical preparation thereof | |
| CN100345554C (en) | Compounding medicinal capsule for treating angiitis | |
| CN1265829C (en) | Healthy product for preventing and treating cardiovascular and cerebrovascular disease | |
| CN1115160C (en) | Orally-applied medicine for treating hyperosteogeny |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |