CN105816557A - Infant traditional Chinese medicine fever-reducing paste and preparation method thereof - Google Patents

Infant traditional Chinese medicine fever-reducing paste and preparation method thereof Download PDF

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Publication number
CN105816557A
CN105816557A CN201610238488.0A CN201610238488A CN105816557A CN 105816557 A CN105816557 A CN 105816557A CN 201610238488 A CN201610238488 A CN 201610238488A CN 105816557 A CN105816557 A CN 105816557A
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parts
chinese medicine
fever
paste
raw material
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袁贯丽
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to an infant traditional Chinese medicine fever-reducing paste and a preparation method thereof. The infant traditional Chinese medicine fever reducing paste is prepared from the following raw materials in parts by weight: 5-12 parts of fructus evodiae, 5-15 parts of radix achyranthis bidentatae, 5-15 parts of rheum officinale, 3-8 parts of coptis chinensis and 5-12 parts of jasmine. The infant traditional Chinese medicine fever-reducing paste is simple in preparation process, stable and exact in curative effect and low in price, has a pure traditional Chinese medicine formula, does not have any toxic or side effect to the human body and has the effects of removing toxins and reducing fever.

Description

A kind of child's Chinese medicine is brought down a fever patch and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of child's Chinese medicine and bring down a fever patch and preparation method thereof.
Background technology
Heating is the common sympton of multiple disease.Children's's normal body temperature is often with anus temperature 36.5~37.5 DEG C, axil temperature 36~37 DEG C of measurements.Under normal circumstances, axil temperature is lower than mouth temperature (Sublingual) 0.2~0.5 DEG C, and anus temperature is than axil Wen Yuegao about 0.5 DEG C.If axil temperature more than body temperature fluctuation between 37.4 DEG C, and a day more than more than 1 DEG C, it is believed that heating.So-called low grade fever, refers to that axil temperature is that 37.5 DEG C~38 DEG C, moderate heat 38.1~39 DEG C, high heat 39.1~40 DEG C, excessive heat are then more than 41 DEG C.Fever of children is pathological process common in infant infectious diseases, the growth of the child not only affected, it is also possible to bring other complication.If children's continues high heat, it is possible to affect the growth of brain, so we are looking after the little childhood generated heat, control body temperature the most exactly, it is impossible to burning the highest.Baby within World Health Organization (WHO) advises 2 months prohibits the use of any medicine of bringing down a fever.
Development along with China's Chinese medicine, for infantile hyperpyrexia, it is little for infantile hyperpyrexia side effect that people appreciate Chinese medicine gradually, bear painful little advantage, and organic conception is paid attention in Chinese traditional treatment, pay attention to comprehensive control, pay attention to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, therapeutic effect more demonstrates the Chinese medicine advantage for infantile hyperpyrexia.Chinese medicine has endocrine regulation, for infantile hyperpyrexia, improve qi-blood circulating, the special efficacy coughed of dispelling, and persistent, treating both the principal and secondary aspects of a disease, have no side effect and efficacy consolidation, be difficult to recurrence.
Therefore it provides a kind of preparation technology is simple, pure Chinese medicine formula, to human non-toxic's side effect, the child's Chinese medicine effectively brought down a fever patch and preparation method thereof of bringing down a fever has wide market.
Summary of the invention
The present invention seeks to the deficiency for solving above-mentioned technical problem, it is provided that a kind of preparation technology is simple, pure Chinese medicine formula, to human non-toxic's side effect, the child's Chinese medicine effectively brought down a fever is brought down a fever patch and preparation method thereof, for making up the defect of prior art.
The technical scheme is that and be achieved in that: a kind of child's Chinese medicine is brought down a fever patch, and it is to be prepared from by the raw material of following parts by weight: Fructus Evodiae 5 to 12 parts, Radix Achyranthis Bidentatae 5 to 15 parts, Radix Et Rhizoma Rhei 5 to 15 parts, Rhizoma Coptidis 3 to 8 parts, Fructus Gardeniae 5 to 12 parts.
It is to be prepared from by the raw material of following parts by weight: Fructus Evodiae 9 parts, Radix Achyranthis Bidentatae 10 parts, Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 5 parts, Fructus Gardeniae 9 parts.
Its preparation method is as follows:
1) choosing above-mentioned raw materials, be placed in drying baker by above-mentioned raw materials and be dried, drying time is 60 minutes, and baking temperature is 65 degrees Celsius;
2) by raw material pulverizing dried in step 1) to 150 mesh, the raw material mix homogeneously after then pulverizing, obtain compound;
3) by step 2) in the compound of gained join big fire in water and boil; amount of water is 8 to 10 times of compound; big fire turns little fire after boiling and simmers slowly to paste, then ceases fire stewing 3 to 5 minutes, is sufficiently stirred for obtaining thick paste; by medical proof fabric according to long 10 centimetres; wide 5 centimetres of segmentations, paste lastblock absorbent cotton, coat thick paste on absorbent cotton in the middle part of medical proof fabric; and seal 15 hours, pack and i.e. obtain Chinese medicine and bring down a fever patch.
The present invention has no side effect, and prescription drug pharmacology is:
Fructus Evodiae: pungent, bitter, hot;Slightly poisonous.Return liver, spleen, stomach, kidney channel.Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, and gastral cavity abdomen hypochondriac pain vomits acid regurgitation, Diarrhoea.
Radix Achyranthis Bidentatae: bitter, sweet, acid, flat.Return liver, kidney channel.Eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.For amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizziness, toothache, and aphtha is spitted blood, epistaxis.
Radix Et Rhizoma Rhei: bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, dampness removing jaundice eliminating.Stagnating constipation for excess-heat, heat in blood tells nosebleed, conjunctival congestion pharyngeal swelling, carbuncle furuncle, abdominalgia with intestinal abscess, blood stasis amenorrhea, postpartum stagnation, traumatic injury, hygropyretic dysentery, jaundice dark coloured urine, stranguria, edema;Externally treating burns and scalds.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.
Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomitting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle;External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tying mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomit acid regurgitation.
Fructus Gardeniae: bitter, cold.GUIXIN, lung, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body;Externally used detumescence pain relieving.Vexed for calentura, jaundice due to damp-heat, the puckery pain of stranguria, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles;External treatment bruise pain.
Usage of the present invention and consumption be: spreads on bilateral Yongquan acupoint (hitting exactly position before the vola heart), external application 12 hours, as heat is moved back not yet, replaceable applies 1 time again.
The present invention has following beneficial effect: preparation technology is simple, pure Chinese medicine formula, and stable curative effect is definite, cheap, and to human non-toxic's side effect, effectively removing toxic substances is brought down a fever.
Detailed description of the invention
A kind of child's Chinese medicine is brought down a fever patch, and it is to be prepared from by the raw material of following parts by weight: Fructus Evodiae 5 to 12 parts, Radix Achyranthis Bidentatae 5 to 15 parts, Radix Et Rhizoma Rhei 5 to 15 parts, Rhizoma Coptidis 3 to 8 parts, Fructus Gardeniae 5 to 12 parts.It is to be prepared from by the raw material of following parts by weight: Fructus Evodiae 9 parts, Radix Achyranthis Bidentatae 10 parts, Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 5 parts, Fructus Gardeniae 9 parts.Its preparation method is as follows: 1) choose above-mentioned raw materials, is placed in drying baker by above-mentioned raw materials and is dried, and drying time is 60 minutes, and baking temperature is 65 degrees Celsius;2) by raw material pulverizing dried in step 1) to 150 mesh, the raw material mix homogeneously after then pulverizing, obtain compound;3) by step 2) in the compound of gained join big fire in water and boil; amount of water is 8 to 10 times of compound; big fire turns little fire after boiling and simmers slowly to paste, then ceases fire stewing 3 to 5 minutes, is sufficiently stirred for obtaining thick paste; by medical proof fabric according to long 10 centimetres; wide 5 centimetres of segmentations, paste lastblock absorbent cotton, coat thick paste on absorbent cotton in the middle part of medical proof fabric; and seal 15 hours, pack and i.e. obtain Chinese medicine and bring down a fever patch.
Embodiment 1: taking Fructus Evodiae 5 grams, Radix Achyranthis Bidentatae 5 grams, Radix Et Rhizoma Rhei 5 grams, Rhizoma Coptidis 3 grams, Fructus Gardeniae 5 grams, be placed in drying baker by above-mentioned raw materials and be dried, drying time is 60 minutes, and baking temperature is 65 degrees Celsius;By dried raw material pulverizing to 150 mesh, the raw material mix homogeneously after then pulverizing, obtain compound;Add mixture into big fire in water to boil; amount of water is 8 to 10 times of compound; big fire turns little fire after boiling and simmers slowly to paste, then ceases fire stewing 3 to 5 minutes, is sufficiently stirred for obtaining thick paste; by medical proof fabric according to long 10 centimetres; wide 5 centimetres of segmentations, paste lastblock absorbent cotton, coat thick paste on absorbent cotton in the middle part of medical proof fabric; and seal 15 hours, pack and i.e. obtain Chinese medicine and bring down a fever patch.
Embodiment 2: taking Fructus Evodiae 12 grams, Radix Achyranthis Bidentatae 15 grams, Radix Et Rhizoma Rhei 15 grams, Rhizoma Coptidis 8 grams, Fructus Gardeniae 12 grams, be placed in drying baker by above-mentioned raw materials and be dried, drying time is 60 minutes, and baking temperature is 65 degrees Celsius;By dried raw material pulverizing to 150 mesh, the raw material mix homogeneously after then pulverizing, obtain compound;Add mixture into big fire in water to boil; amount of water is 8 to 10 times of compound; big fire turns little fire after boiling and simmers slowly to paste, then ceases fire stewing 3 to 5 minutes, is sufficiently stirred for obtaining thick paste; by medical proof fabric according to long 10 centimetres; wide 5 centimetres of segmentations, paste lastblock absorbent cotton, coat thick paste on absorbent cotton in the middle part of medical proof fabric; and seal 15 hours, pack and i.e. obtain Chinese medicine and bring down a fever patch.
Embodiment 3: taking Fructus Evodiae 9 grams, Radix Achyranthis Bidentatae 10 grams, Radix Et Rhizoma Rhei 10 grams, Rhizoma Coptidis 5 grams, Fructus Gardeniae 9 grams, be placed in drying baker by above-mentioned raw materials and be dried, drying time is 60 minutes, and baking temperature is 65 degrees Celsius;By dried raw material pulverizing to 150 mesh, the raw material mix homogeneously after then pulverizing, obtain compound;Add mixture into big fire in water to boil; amount of water is 8 to 10 times of compound; big fire turns little fire after boiling and simmers slowly to paste, then ceases fire stewing 3 to 5 minutes, is sufficiently stirred for obtaining thick paste; by medical proof fabric according to long 10 centimetres; wide 5 centimetres of segmentations, paste lastblock absorbent cotton, coat thick paste on absorbent cotton in the middle part of medical proof fabric; and seal 15 hours, pack and i.e. obtain Chinese medicine and bring down a fever patch.

Claims (3)

1. child's Chinese medicine is brought down a fever patch, it is characterised in that it is to be prepared from by the raw material of following parts by weight: Fructus Evodiae 5 to 12 parts, Radix Achyranthis Bidentatae 5 to 15 parts, Radix Et Rhizoma Rhei 5 to 15 parts, Rhizoma Coptidis 3 to 8 parts, Fructus Gardeniae 5 to 12 parts.
Child's Chinese medicine the most according to claim 1 is brought down a fever patch, it is characterised in that it is to be prepared from by the raw material of following parts by weight: Fructus Evodiae 9 parts, Radix Achyranthis Bidentatae 10 parts, Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 5 parts, Fructus Gardeniae 9 parts.
3. child's Chinese medicine as claimed in claim 1 is brought down a fever the preparation method of patch, it is characterised in that its preparation method is as follows:
1) choosing above-mentioned raw materials, be placed in drying baker by above-mentioned raw materials and be dried, drying time is 60 minutes, and baking temperature is 65 degrees Celsius;
2) by raw material pulverizing dried in step 1) to 150 mesh, the raw material mix homogeneously after then pulverizing, obtain compound;
3) by step 2) in the compound of gained join big fire in water and boil; amount of water is 8 to 10 times of compound; big fire turns little fire after boiling and simmers slowly to paste, then ceases fire stewing 3 to 5 minutes, is sufficiently stirred for obtaining thick paste; by medical proof fabric according to long 10 centimetres; wide 5 centimetres of segmentations, paste lastblock absorbent cotton, coat thick paste on absorbent cotton in the middle part of medical proof fabric; and seal 15 hours, pack and i.e. obtain Chinese medicine and bring down a fever patch.
CN201610238488.0A 2016-04-18 2016-04-18 Infant traditional Chinese medicine fever-reducing paste and preparation method thereof Pending CN105816557A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648358A (en) * 2017-11-22 2018-02-02 蚌埠崇迪生物科技有限公司 It is a kind of defervescence plaster used and preparation method thereof
CN107737180A (en) * 2017-11-22 2018-02-27 蚌埠崇迪生物科技有限公司 A kind of externally-applied febricide medicinal agent and preparation method thereof
CN107929406A (en) * 2017-12-28 2018-04-20 刘国锋 If a kind of ligusticumic umbrella and its application method
CN111671807A (en) * 2020-07-20 2020-09-18 玉林师范学院 External traditional Chinese medicine composition for children defervescence, gel plaster and preparation method thereof
CN111773305A (en) * 2020-08-07 2020-10-16 亳州益智健康产业有限公司 Pure traditional Chinese medicine fever reducing plaster for children and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1213559A (en) * 1998-10-28 1999-04-14 孙德培 External-use plaster for cooling and bring down fever, its preparing method and use
CN102846993A (en) * 2012-09-28 2013-01-02 於晶 Externally-used plaster for treating infantile febrile convulsion
CN104857237A (en) * 2015-05-27 2015-08-26 济南方宇文化传媒有限公司 Fever reducing paste, prepared from pure traditional Chinese medicines, for treating infantile diarrhea, and preparation method of fever reducing paste
CN104888123A (en) * 2015-06-15 2015-09-09 韦洪伟 Preparation for infantile respiratory tract infection as well as preparation method and detection method thereof
CN104998200A (en) * 2015-07-30 2015-10-28 庞群 Herpetic keratitis and treatment traditional Chinese medicine thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1213559A (en) * 1998-10-28 1999-04-14 孙德培 External-use plaster for cooling and bring down fever, its preparing method and use
CN102846993A (en) * 2012-09-28 2013-01-02 於晶 Externally-used plaster for treating infantile febrile convulsion
CN104857237A (en) * 2015-05-27 2015-08-26 济南方宇文化传媒有限公司 Fever reducing paste, prepared from pure traditional Chinese medicines, for treating infantile diarrhea, and preparation method of fever reducing paste
CN104888123A (en) * 2015-06-15 2015-09-09 韦洪伟 Preparation for infantile respiratory tract infection as well as preparation method and detection method thereof
CN104998200A (en) * 2015-07-30 2015-10-28 庞群 Herpetic keratitis and treatment traditional Chinese medicine thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648358A (en) * 2017-11-22 2018-02-02 蚌埠崇迪生物科技有限公司 It is a kind of defervescence plaster used and preparation method thereof
CN107737180A (en) * 2017-11-22 2018-02-27 蚌埠崇迪生物科技有限公司 A kind of externally-applied febricide medicinal agent and preparation method thereof
CN107929406A (en) * 2017-12-28 2018-04-20 刘国锋 If a kind of ligusticumic umbrella and its application method
CN111671807A (en) * 2020-07-20 2020-09-18 玉林师范学院 External traditional Chinese medicine composition for children defervescence, gel plaster and preparation method thereof
CN111773305A (en) * 2020-08-07 2020-10-16 亳州益智健康产业有限公司 Pure traditional Chinese medicine fever reducing plaster for children and preparation method thereof

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Application publication date: 20160803