CN103356922B - Traditional Chinese medicine granule used for treating liver and gallbladder damp-heat icterus - Google Patents

Abstract

The invention discloses a traditional Chinese medicine granule used for treating liver and gallbladder damp-heat icterus, and relates to a traditional Chinese medicine preparation. The traditional Chinese medicine granule is characterized by being prepared from the following raw traditional Chinese medicines in percentage by weight: 10.2 to 12.5% of capillary Artemisia, 3.3 to 4.1% of coptis chinensis, 1.9 to 2.4% of ginger processed pinellia, 10.2 to 12.5% of trichosanthes kirilowii Maxim, 3.3 to 4.1% of immature bitter orange, 5.0 to 6.2% of cortex magnoliae officinalis, 5.0 to 6.2% of poria cocos, 5.0 to 6.2% of semen coicis, 5.0 to 6.2% of white hyacinth Bean, 10.2 to 12.5% of rhizoma dioscoreae, 10.2 to 12.5% of rhizoma imperatae, 5.0 to 6.2% of endothelium corneum gigeriae galli, 5.0 to 6.2% of dandelion, 5.0 to 6.2% of dark plum, and 5.0 to 6.2% of lycium chinense. The traditional Chinese medicine granule is convenient to take, high in pointing to symtoms, fast to come into effect, and good in treatment effect, and has the recovery rate of 88.8% and effective rate of 100%.

Description

A kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice

Technical field

The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice.

Background technology

The damp and hot pathogenic factor of jaundice system impression, retardance liver and gall, mechanism of qi is obstructed, and catharsis is not normal, due to bile is excessive.Take the disease that icteric sclera, yellowish body, yellow urine be main clinical manifestation.Be more common in hepatobiliary system disease.Clinical manifestation is: skin, sclera etc. is organized xanthochromia, and when jaundice is deepened, urine, expectorant, tear and perspiration are also by xanthochromia; The color change of urine and excrement; With abdominal distention, stomachache, inappetence, feel sick, vomiting, diarrhea or constipation; Or loss of appetite, feel sick, detest greasy, fatigue and weak, yellowish urine as symptoms such as tea, hepatalgia, heating, oliguria.Doctor trained in Western medicine is thought: the reason that causes jaundice is: or hematoclasis increase, bilirubin generates too much; Or liver cell lesion to cause bilirubin metabolism not normal; Or the inside and outside biliary system generation of liver mechanical obstruction, affect bilirubinic excretion; Or hepatocyte has some birth defect, can not complete bilirubinic homergy.Symptomatic therapy is taked in treatment, and conventional oral medicine has prednisone, methotrexate, ciclosporin etc.; In addition, according to the state of an illness, implement the method treatments such as blood transfusion, drain.The Therapeutic Method of doctor trained in Western medicine is to take stopgap measures, and internal organs comprehensively regulating that can not be to patient, effects a permanent cure far away from the traditional Chinese medical science.The traditional Chinese medical science is thought: the basic pathogenesis of jaundice is turbid damp retardance.Or diseases caused by exogenous pathogenic factor turbid damp, damp and hot, epidemic disease is malicious etc., and seasonal pathogen enters from mouth, pents up in middle Jiao, transporting and transforming function of the spleen and stomach is not normal, and damp and hot fumigating in taste involved liver and gall; Or injury due to diet irregular diet or be addicted to drink excessively, all can impairing the spleen and stomach, so that transportation capabilities dereliction of duty, endogenous damp formation, stifling or block in taste liver and gall; Or plain body body weakness of the spleen and stomach, overstrain, damage of the spleen loses fortune, deficiency of qi and blood, the liver failing to be nourished of a specified duration.Cause suffocating of liver and gall not normal, bile overflows and jaundice occurs.In treatment, the traditional Chinese medical science is particular about determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, so, abide by the medical knowledge of the traditional Chinese medical science, the medicine that development minute disease type is treated jaundice is very necessary.

Summary of the invention

The object of the present invention is to provide a kind of disease type for the treatment of, suiting the medicine to the illness property is strong, and effective fast, therapeutic effect is good, this kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice of taking convenience.

In order to reach above object, the technical solution used in the present invention is: this kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice, it is characterized in that: it is to be made by the raw material of Chinese medicine of following percentage by weight: Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4%, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, Fructus Lycii 5.0-6.2%, wherein each raw material of Chinese medicine constituent content percent sum equals 100%.Optimizing prescription is: Herba Artemisiae Scopariae 11.4%, Rhizoma Coptidis 3.7%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2%, Fructus Trichosanthis 11.4%, Fructus Aurantii Immaturus 3.7%, Cortex Magnoliae Officinalis 5.6%, Poria 5.6%, Semen Coicis 5.6%, Semen Lablab Album 5.6%, Rhizoma Dioscoreae 11.4%, Rhizoma Imperatae 11.4%, Endothelium Corneum Gigeriae Galli 5.6%, Herba Taraxaci 5.6%, Fructus Mume 5.6%, Fructus Lycii 5.6%.This a kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice, by following steps, made: one, by Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4%, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, the ratio of Fructus Lycii 5.0-6.2% accurately takes each raw material of Chinese medicine cooking, in taking each during spice, by raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae is mixed puts together, Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis is mixed puts together, Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii is mixed puts together, two, by weighing up mixed raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae of putting and be placed at the temperature of drying baker 70-80 ℃ dry 24 hours, be down to natural temperature, be ground into the Chinese medicine fine powder of 60 mesh sieves, standby, three, by weighing up mixed raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis of putting, put into multifunctional extracting pot, add domestic water, stir, the amount that adds water is alleged Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis quality sum 7-8 times, soak 20 minutes, volatile oil is carried in heating, and the time of carrying is 60 minutes, carries complete, take off volatile oil cold preservation standby, medicine liquid mixture in multifunctional extracting pot is filtered, stay slag, obtain filtering liquid medicine, four, by weighing up mixed raw material of Chinese medicine Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii of putting, put into medicine boiler, add domestic water, stir, the amount that adds water is alleged Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 5-6 times, soaks 30 minutes, intense fire is heated to boil, change slow fire boiling 60 minutes, stop heating, filter, stay slag, obtain medicinal liquid one time, five, the medicinal residues in multifunctional extracting pot are incorporated to medicine boiler, add domestic water, stir, amount of water is alleged raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Coptidis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Fructus Trichosanthis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 4-5 times, and intense fire is heated to boil, change slow fire boiling 60 minutes, stop heating, filter, obtain secondary medicinal residues, squeezing medicinal residues, obtain squeezing medicinal residues, six, filtering liquid medicine, medicinal liquid, secondary medicinal liquid, a squeezing medicinal liquid are all incorporated to stainless steel cylinder, obtain admixing medical solutions, in admixing medical solutions, add chitin, stir evenly, the addition of chitin is that 3/0,000,45 ℃ of admixing medical solutions quality are incubated 10 hours, get supernatant liquid filtering, waste, obtains purification medicinal liquid, seven, purification medicinal liquid is added to medicine boiler, heating is concentrated, and being concentrated into relative density is 1.30～1.35, stops heating, and cooling, obtains Chinese medicine thick paste naturally, eight, in Chinese medicine thick paste, add standby mixing fine powders, mix thoroughly, then add edible ethanol, the addition of edible ethanol is 1/5～1/4 of mixing fine powders quality, mixes softeningly, by 12 mesh sieves of granulation machine, makes Chinese medicine wet granular, nine, Chinese medicine wet granular is put into drip pan, be placed in baking oven 60-80 ℃ dry, do to moisture lower than 2% time, stop heating, naturally lower the temperature, obtain the dry granule of Chinese medicine, ten, the dry granule stranding of Chinese medicine is broken, volatile oil is evenly sprayed on it, to mix thoroughly, airtight placement absorbs volatile oil for 48 hours, pack, sealing, every bag of 10g, is a kind of Chinese medicinal granule finished product for the treatment of liver gallbladder damp-heat type jaundice.

This kind of prescription pharmacology for the treatment of the Chinese medicinal granule of liver gallbladder damp-heat type jaundice is: heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting, dampness removing jaundice eliminating, invigorating the spleen and regulating the stomach, nourishing the liver and kidney.

Wherein, Herba Artemisiae Scopariae bitter in the mouth, pungent, cold nature; Return spleen, stomach, liver, gallbladder meridian.There is clearing away heat-damp and promoting diuresis, the effect of jaundice eliminating.Cure mainly jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis etc.; Pharmaceutical research proof Herba Artemisiae Scopariae has function of gallbladder promoting, and liver function protecting is antipyretic, antiinflammatory, blood fat reducing, the effects such as coronary dilating.

Rhizoma Coptidis bitter in the mouth, cold in nature; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is heat clearing and damp drying, the effect of eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle.

Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) acrid in the mouth, warm in nature; Return spleen, stomach, lung meridian.There is warming middle-JIAO and reduce phlegm, the effect of stopping nausea and vomiting by lowering the adverse flow of QI.Cure mainly vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.

Fructus Trichosanthis sweetness and bitterness, cold in nature; Return lung, stomach, large intestine channel.There is lung moistening, reduce phlegm, eliminating stagnation, the effect of intestine moistening.Cure mainly phlegm-heat cough, the thoracic obstruction, blocked-up chest, consumptive lung disease hemoptysis, quenches one's thirst, jaundice, constipation, carbuncle from the beginning of.

Fructus Aurantii Immaturus bitter in the mouth, pungent, cold in nature.Return spleen, stomach, liver, heart channel.Cure mainly in stagnant and stop, feeling of fullness distending pain, constipation, heavy after dysentery, blocked-up chest, gastroptosis, uterine prolapse, proctoptosis.Pharmacological research: Fructus Aurantii Immaturus has diuresis.

Cortex Magnoliae Officinalis bitter in the mouth, pungent, warm in nature; Return spleen, stomach, large intestine channel.Have circulation of qi promoting removing food stagnancy, dampness is removed full, the effect of lowering the adverse QI to relieve asthma; Cure mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough.

Poria sweet in the mouth, light, property is flat; GUIXIN warp, lung meridian, spleen channel, kidney channel.The effect with promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful.

Semen Coicis slightly sweet flavor, cool in nature; Return spleen, stomach, lung meridian.The function with spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, diuretic.Semen Coicis property is partially cold and cool, is longer than promoting diuresis to eliminate damp pathogen, clearing away heat and discharging pus, and eliminating impediment pain relieving, is usually used in dysuria, edema, beriberi, lung abscess, acute appendicitis, rheumatic arthralgia, muscle arteries and veins contraction urgency and damp-warm diseases are at edema caused by disorder of QI.

Semen Lablab Album slightly sweet flavor, property is flat; Return spleen channel, stomach warp.There is spleen invigorating, removing dampness, the effect of relieving summer heat.Cure mainly: insufficiency of the spleen resulting in production of dampness, anorexia and loose stool, leukorrhagia, heat-damp in summer is vomited and diarrhoea, and excessive thirst is uncomfortable in chest.

Rhizoma Dioscoreae sweet in the mouth, property is flat; Return spleen, lung, kidney channel.There is spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the effect of the kidney invigorating arresting seminal emission.Cure mainly insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.

Rhizoma Imperatae sweet in the mouth, cold in nature; Return lung, stomach, small intestine meridian.There is removing heat from blood, hemostasis, heat clearing away, the effect of diuresis.Cure mainly calentura excessive thirst, spit blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.

Endothelium Corneum Gigeriae Galli sweet in the mouth, cold in nature; Return spleen, stomach, small intestinal, urinary bladder channel.There is promoting digestion and invigorating the stomach, the effect of arresting seminal emission.

Herba Taraxaci sweet in the mouth, micro-hardship, cold in nature.Return spleen, stomach, kidney three warps.There is heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation.Cure mainly upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.

Fructus Mume sour in the mouth, puckery, property is flat; Return liver, spleen, lung, large intestine channel.Have promote the production of body fluid, quench the thirst, astringe the lung, the effect of astringing intestine to stop diarrhea, relieving colic caused by ascaris worm, cure mainly chronic cough of deficiency lung, deficiency-heat excessive thirst, chronic malaria, chronic diarrhea, dysentery, has blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis.Research shows: the malic acid in Fructus Mume can be guided to large intestine appropriate moisture, forms feces and excretes, with appetite stimulator.

Fructus Lycii sweet in the mouth, property is flat; Return liver, kidney, lung meridian.There is nourishing the liver and kidney, the effect of replenishing vital essence to improve eyesight.Cure mainly chronic consumptive disease damage of essence, soreness of waist and knee joint; Vertigo and tinnitus, interior-heat Xiao are thirsty, blood deficiency and yellow complexion, and blurred vision is not clear.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual deterioration; Soreness of the waist and knees; Seminal emission is quenched one's thirst; Cough due to consumptive disease.

This kind of instructions of taking for the treatment of the Chinese medicinal granule of liver gallbladder damp-heat type jaundice: after meal half an hour warm boiled water, early, evening each once, be grown up each 2 bags, child's dosing is cut down according to the circumstance.It within 20 days, is a course for the treatment of.

Taboo: period in a medicine is avoided raw, cold, zest and delicious food savoury.Anemia of pregnant woman is cautious use of.

Beneficial effect of the present invention is: a kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice is provided, and this Chinese medicinal granule taking convenience, suiting the medicine to the illness property is strong, and effective fast, therapeutic effect is good, and cure rate is 88.8%, effective percentage 100%.

Analysis of clinical

One, diagnosis basis

Jaundice dampness-heat in the liver and gallbladder disease type diagnostic criteria according to Chinese medicine industry standard (disease of tcm Standardization of diagnosis and curative effect) the > > of the < < People's Republic of China (PRC) (ZY/T001.1-94) regulation is formulated:

1, yellow skin and eye is yellow distinct.Generate heat thirsty, regretful Nang in the heart, xerostomia and covering with mat, the tending to vomit of feeling sick, abdominal distention hypochondriac pain, constipation or be canescence, oliguria with yellow urine.

2, red tongue, yellow and greasy fur, wiry and frequent pulse.

3, there is eating and drinking without temperance, the medical histories such as hepatitis contact or applied chemistry goods medicine.

4, liver, spleen or gallbladder enlargement, with tenderness or tenderness.

Two, criterion of therapeutical effect

Jaundice liver criterion of therapeutical effect according to Chinese medicine industry standard (disease of tcm Standardization of diagnosis and curative effect) the > > of the < < People's Republic of China (PRC) (ZY/T001.1-94) regulation is formulated:

1, cure: jaundice disappears, other transference cures, lab index is normal.

2, take a turn for the better: jaundice and other symptoms alleviate, bilirubin is normal or reduce other lab index improvements.

3, do not heal: jaundice is not moved back or deepened, other symptoms and lab index are without improvement.

Three, therapeutic effect analysis

From in January, 2011 to 2012 year December, make a definite diagnosis altogether liver gallbladder damp-heat type Patients with Jaundice 125 examples, male patient's 89 examples wherein, female patient 36 examples, oldest 81 years old, minimum 9 years old, take this kind of 2～3 courses for the treatment of of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice, cure 111 examples, cure rate 88.8%, 14 examples that take a turn for the better, effective percentage 100%.

Specific embodiment

Embodiment 1

By Herba Artemisiae Scopariae 11.4%, Rhizoma Coptidis 3.7%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2%, Fructus Trichosanthis 11.4%, Fructus Aurantii Immaturus 3.7%, Cortex Magnoliae Officinalis 5.6%, Poria 5.6%, Semen Coicis 5.6%, Semen Lablab Album 5.6%, Rhizoma Dioscoreae 11.4%, Rhizoma Imperatae 11.4%, Endothelium Corneum Gigeriae Galli 5.6%, Herba Taraxaci 5.6%, Fructus Mume 5.6%, the ratio of Fructus Lycii 5.6% accurately takes each raw material of Chinese medicine 100kg cooking, wherein, Herba Artemisiae Scopariae 11.4kg, Rhizoma Coptidis 3.7kg, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2kg, Fructus Trichosanthis 11.4kg, Fructus Aurantii Immaturus 3.7kg, Cortex Magnoliae Officinalis 5.6kg, Poria 5.6kg, Semen Coicis 5.6kg, Semen Lablab Album 5.6kg, Rhizoma Dioscoreae 11.4kg, Rhizoma Imperatae 11.4kg, Endothelium Corneum Gigeriae Galli 5.6kg, Herba Taraxaci 5.6kg, Fructus Mume 5.6kg, Fructus Lycii 5.6kg, in taking each during spice, by raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae is mixed puts together, Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis is mixed puts together, and Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii is mixed puts together, by weighing up mixed raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae of putting and be placed at the temperature of drying baker 70-80 ℃ dry 24 hours, be down to natural temperature, be ground into the Chinese medicine fine powder of 60 mesh sieves, standby, by weighing up mixed raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis of putting, put into multifunctional extracting pot, add domestic water 150kg, stir, soak 20 minutes, volatile oil is carried in heating, the time of carrying is 60 minutes, carry completely, take off volatile oil cold preservation standby, the medicine liquid mixture in multifunctional extracting pot is filtered, stay slag, obtain filtering liquid medicine, by weighing up mixed raw material of Chinese medicine Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii of putting, put into medicine boiler, add domestic water 340kg, stir, soak 30 minutes, intense fire is heated to boil, and changes slow fire boiling 60 minutes, stop heating, filter, stay slag, obtain medicinal liquid one time, medicinal residues in multifunctional extracting pot are incorporated to medicine boiler, add domestic water 350kg, stir, intense fire is heated to boil, and changes slow fire boiling 60 minutes, stops heating, filters, and obtains secondary medicinal residues, and squeezing medicinal residues, obtain squeezing medicinal residues, six, filtering liquid medicine, medicinal liquid, secondary medicinal liquid, a squeezing medicinal liquid are all incorporated to stainless steel cylinder, obtain admixing medical solutions, in admixing medical solutions, add chitin, stir evenly, the addition of chitin is that 3/0,000,45 ℃ of admixing medical solutions quality are incubated 10 hours, get supernatant liquid filtering, waste, obtains purification medicinal liquid, seven, purification medicinal liquid is added to medicine boiler, heating is concentrated, and being concentrated into relative density is 1.30～1.35, stops heating, and cooling, obtains Chinese medicine thick paste naturally, eight, in Chinese medicine thick paste, add standby mixing fine powders, mix thoroughly, then add edible ethanol, the addition of edible ethanol is 1/5～1/4 of mixing fine powders quality, mixes softeningly, by 12 mesh sieves of granulation machine, makes Chinese medicine wet granular, nine, Chinese medicine wet granular is put into drip pan, be placed in baking oven 60-80 ℃ dry, do to moisture lower than 2% time, stop heating, naturally lower the temperature, obtain the dry granule 30.1kg of Chinese medicine, ten, the dry granule stranding of Chinese medicine is broken, volatile oil is evenly sprayed on it, to mix thoroughly, airtight placement absorbs volatile oil for 48 hours, pack, sealing, every bag of 10g, is a kind of Chinese medicinal granule finished product for the treatment of liver gallbladder damp-heat type jaundice.

By these a kind of Chinese medicinal granule treatment dampness-heat in the liver and gallbladder patient 44 examples for the treatment of liver gallbladder damp-heat type jaundice, cure 40 examples, cure rate 90.9%; 4 examples that take a turn for the better, improvement rate 9.1%; Effective percentage 100%.

Model case

Wei * *, man, 46 years old, Yan Zhuan town, Laiwu City Gangcheng District peasant.On June 11st, 2011 is to our hospital.Main suit: before 10 days, without inducement, there is malaise, inappetence, the tending to vomit of sometimes feeling sick,, then there is icteric sclera, yellowish body, yellowish urine in activity postemphasis, and companion upper right abdomen dull pain is uncomfortable, and without diarrhoea, without heating, without nervous uncomfortable in chest, no headache is dizzy, and it is poor that sleep night.Morbidity Hou Zhe village clinic is by " gastritis " medication treatment, and the state of an illness, without improvement, is examined out of admiration for a famous person.Examine and see: shallow complexion, whole skin xanthochromia, the obvious xanthochromia of sclera, upper right abdominal pressure pain, pain is kowtowed in hepatic region; Red tongue, yellow and greasy fur, stringy pulse.Look into liver function and show glutamate pyruvate transaminase 261U/L, GOT2 11U/L, total bilirubin 180.6umol/L, blood fat, blood glucose and routine blood test result are normal, and color ultrasound is shown liver parenchyma lesion, and electrocardiogram result is normal.Be diagnosed as liver gallbladder damp-heat type jaundice, take this Chinese medicinal granule treatment, after the course for the treatment of, subjective symptoms alleviates, and liver function takes a turn for the better, and total bilirubin is down to 60.36umol/L; General malaise transference cure after two courses for the treatment of, check liver function recovery is normal, and total bilirubin is down to 13.6umol/L; After leaving hospital, adhere to again taking a course for the treatment of of this Chinese medicinal granule, follow up a case by regular visits to 1 year without recurrence.

Embodiment 2

By Herba Artemisiae Scopariae 11.5%, Rhizoma Coptidis 3.5%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.0%, Fructus Trichosanthis 11.0%, Fructus Aurantii Immaturus 3.5%, Cortex Magnoliae Officinalis 5.5%, Poria 5.5%, Semen Coicis 5.5%, Semen Lablab Album 5.5%, Rhizoma Dioscoreae 11.0%, Rhizoma Imperatae 11.5%, Endothelium Corneum Gigeriae Galli 6.0%, Herba Taraxaci 6.0%, Fructus Mume 6.0%, the ratio of Fructus Lycii 6.0% accurately takes each raw material of Chinese medicine 100kg cooking, wherein, Herba Artemisiae Scopariae 11.5kg, Rhizoma Coptidis 3.5kg, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2kg, Fructus Trichosanthis 11kg, Fructus Aurantii Immaturus 3.5kg, Cortex Magnoliae Officinalis 5.5kg, Poria 5.5kg, Semen Coicis 5.5kg, Semen Lablab Album 5.5kg, Rhizoma Dioscoreae 11kg, Rhizoma Imperatae 11.5kg, Endothelium Corneum Gigeriae Galli 6kg, Herba Taraxaci 6kg, Fructus Mume 6kg, Fructus Lycii 6kg.

Manufacture method is with embodiment 1.

By these a kind of Chinese medicinal granule treatment dampness-heat in the liver and gallbladder patient 40 examples for the treatment of liver gallbladder damp-heat type jaundice, cure 35 examples, cure rate 87.5%; 5 examples that take a turn for the better, improvement rate 12.5%; Effective percentage 100%.

Model case

Lee * *, man, 63 years old, Laiwu City Laicheng district teacher.December in 2011 6 days is because of weak, poor appetite 3 years, increases the weight of to accompany icteric sclera, yellowish urine 7 days to our hospital.Main suit: occurred malaise without inducement before 3 years, activity postemphasis, inappetence, sometimes the tending to vomit of feeling sick, and upper right abdomen dull pain, is diagnosed as in the court " chronic hepatitis B ", and sb.'s illness took a favorable turn in more than 20 days to give the Drug therapys such as hepatoprotective antiinflammatory, antiviral in hospital, long-term taking antiviral drugs over 3 years, is interrupted and takes liver-protecting medicine.Before 7 days, without inducement, occurred that weak, poor appetite increased the weight of, companion's icteric sclera, yellowish urine, upper right abdomen dull pain is uncomfortable, and without diarrhoea, without heating, without nervous uncomfortable in chest, no headache is dizzy, and it is poor that sleep night.After morbidity, do not take notice of at that time, but the state of an illness gradually increases the weight of, then examine.Examine and see: dim complexion, whole skin xanthochromia, the obvious xanthochromia of sclera, upper right abdominal pressure pain, pain is kowtowed in hepatic region; Red tongue, yellow and greasy fur, stringy pulse.Look into liver function and show glutamate pyruvate transaminase 169U/L, glutamate-oxaloacetate transaminase 01U/L, total bilirubin 158.6umol/L, blood fat, blood glucose and routine blood test result are normal, and color ultrasound is shown liver parenchyma lesion, and electrocardiogram result is normal.Be diagnosed as liver gallbladder damp-heat type jaundice, take this Chinese medicinal granule treatment, after the course for the treatment of, subjective symptoms alleviates, and liver function takes a turn for the better, and total bilirubin is down to 80.36umol/L; After two courses for the treatment of, general malaise symptom is obviously improved, and looks into liver function and shows glutamate pyruvate transaminase 79U/L, glutamic oxaloacetic transaminase, GOT 71U/L, and total bilirubin is down to 31.6umol/L; After three courses for the treatment of, subjective symptoms disappears, and liver function recovery is normal, and total bilirubin is down to normally, follows up a case by regular visits to 1 year without recurrence.

Embodiment 3

By Herba Artemisiae Scopariae 12.0%, Rhizoma Coptidis 4.0%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.0%, Fructus Trichosanthis 10.5%, Fructus Aurantii Immaturus 4.0%, Cortex Magnoliae Officinalis 6.0%, Poria 6.0%, Semen Coicis 6.0%, Semen Lablab Album 6.0%, Rhizoma Dioscoreae 10.5%, Rhizoma Imperatae 11.0%, Endothelium Corneum Gigeriae Galli 5.5%, Herba Taraxaci 5.5%, Fructus Mume 5.5%, the ratio of Fructus Lycii 5.5% accurately takes each raw material of Chinese medicine 100kg cooking, wherein, Herba Artemisiae Scopariae 12kg, Rhizoma Coptidis 4kg, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2kg, Fructus Trichosanthis 10.5kg, Fructus Aurantii Immaturus 4kg, Cortex Magnoliae Officinalis 6kg, Poria 6kg, Semen Coicis 6kg, Semen Lablab Album 6kg, Rhizoma Dioscoreae 10.5kg, Rhizoma Imperatae 11kg, Endothelium Corneum Gigeriae Galli 5.5kg, Herba Taraxaci 5.5kg, Fructus Mume 5.5kg, Fructus Lycii 5.5kg.

Manufacture method is with embodiment 1.

By these a kind of Chinese medicinal granule treatment dampness-heat in the liver and gallbladder patient 41 examples for the treatment of liver gallbladder damp-heat type jaundice, cure 36 examples, cure rate 87.8%; 5 examples that take a turn for the better, improvement rate 12.2%; Effective percentage 100%.

Model case

Qi * *, female, 38 years old, Laiwu City Laicheng district worker.On February 10th, 2012 because of weak, poor appetite icteric sclera, yellowish urine more than 10 days to our hospital.Main suit: take continuously a kind of hair growth medicine 2 months, occurred malaise before 10 days without inducement, inappetence, feels sick sometimes, and upper right abdomen dull pain is uncomfortable, then occurs icteric sclera, yellowish body, yellowish urine, without diarrhoea, without heating, without dysurea, frequent micturition, no headache is dizzy, and it is poor that sleep night.Medical at that time after morbidity, think due to fatigue, but the state of an illness gradually increases the weight of, examine out of admiration for a famous person.Examine and see: spirit is poor, yellow complexion, whole skin xanthochromia, the obvious xanthochromia of sclera, heart and lung auscultation is without extremely, upper right abdominal pressure pain, about 2cm under liver rib, touches a tender spot, and kowtow bitterly hepatic region, two lower limb Mild edema; Red tongue, yellow and greasy fur, wiry and frequent pulse.Look into liver function and show glutamate pyruvate transaminase 399U/L, glutamic oxaloacetic transaminase, GOT 301U/L, total bilirubin 178.1umol/L, blood fat, blood glucose and routine blood test result are normal, and color ultrasound is shown liver parenchyma lesion.Be diagnosed as liver gallbladder damp-heat type jaundice, take this Chinese medicinal granule treatment, after the course for the treatment of, subjective symptoms alleviates, and liver function takes a turn for the better, and total bilirubin is down to 90.3umol/L; After two courses for the treatment of, general malaise symptom is obviously improved, and looks into liver function and shows glutamate pyruvate transaminase 68U/L, glutamic oxaloacetic transaminase, GOT 71U/L, and total bilirubin is down to 41.3umol/L; After three courses for the treatment of, subjective symptoms disappears, and liver function recovery is normal, and total bilirubin is down to normally, follows up a case by regular visits to 1 year without recurrence.

Claims (3)

1. a Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice, is characterized in that: it is to be made by the raw material of Chinese medicine of following percentage by weight: Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4%, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, Fructus Lycii 5.0-6.2%; Wherein each raw material of Chinese medicine constituent content percent sum equals 100%.

2. a kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice according to claim 1, it is characterized in that: by following steps, made: one, by Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4%, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, the ratio of Fructus Lycii 5.0-6.2% accurately takes each raw material of Chinese medicine cooking, in taking each during spice, by raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae is mixed puts together, Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis is mixed puts together, Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii is mixed puts together, two, by weighing up mixed raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae of putting and be placed at the temperature of drying baker 70-80 ℃ dry 24 hours, be down to natural temperature, be ground into the Chinese medicine fine powder of 60 mesh sieves, standby, three, by weighing up mixed raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis of putting, put into multifunctional extracting pot, add domestic water, stir, the amount that adds water is alleged Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis quality sum 7-8 times, soak 20 minutes, add hot stripping volatile oil, carrying the time of heating up in a steamer is 60 minutes, carry heat up in a steamer complete, take off volatile oil cold preservation standby, medicine liquid mixture in multifunctional extracting pot is filtered, stay slag, obtain filtering liquid medicine, four, by weighing up mixed raw material of Chinese medicine Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii of putting, put into medicine boiler, add domestic water, stir, the amount that adds water is alleged Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 5-6 times, soaks 30 minutes, intense fire is heated to boil, change slow fire boiling 60 minutes, stop heating, filter, stay slag, obtain medicinal liquid one time, five, the medicinal residues in multifunctional extracting pot are incorporated to medicine boiler, add domestic water, stir, amount of water is alleged raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Coptidis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Fructus Trichosanthis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 4-5 times, and intense fire is heated to boil, change slow fire boiling 60 minutes, stop heating, filter, obtain secondary medicinal residues, squeezing medicinal residues, obtain squeezing medicinal residues, six, filtering liquid medicine, medicinal liquid, secondary medicinal liquid, a squeezing medicinal liquid are all incorporated to stainless steel cylinder, obtain admixing medical solutions, in admixing medical solutions, add chitin, stir evenly, the addition of chitin is that 3/0,000,45 ℃ of admixing medical solutions quality are incubated 10 hours, get supernatant liquid filtering, waste, obtains purification medicinal liquid, seven, purification medicinal liquid is added to medicine boiler, heating is concentrated, and being concentrated into relative density is 1.30～1.35, stops heating, and cooling, obtains Chinese medicine thick paste naturally, eight, in Chinese medicine thick paste, add standby mixing fine powders, mix thoroughly, then add edible ethanol, the addition of edible ethanol is 1/5～1/4 of mixing fine powders quality, mixes softeningly, by 12 mesh sieves of granulation machine, makes Chinese medicine wet granular, nine, Chinese medicine wet granular is put into drip pan, be placed in baking oven 60-80 ℃ dry, do to moisture lower than 2% time, stop heating, naturally lower the temperature, obtain the dry granule of Chinese medicine, ten, the dry granule stranding of Chinese medicine is broken, volatile oil is evenly sprayed on it, to mix thoroughly, airtight placement absorbs volatile oil for 48 hours, pack, sealing, every bag of 10g, is a kind of Chinese medicinal granule finished product for the treatment of liver gallbladder damp-heat type jaundice.

3. a kind of Chinese medicinal granule for the treatment of liver gallbladder damp-heat type jaundice according to claim 1, is characterized in that: optimizing prescription is: Herba Artemisiae Scopariae 11.4%, Rhizoma Coptidis 3.7%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2%, Fructus Trichosanthis 11.4%, Fructus Aurantii Immaturus 3.7%, Cortex Magnoliae Officinalis 5.6%, Poria 5.6%, Semen Coicis 5.6%, Semen Lablab Album 5.6%, Rhizoma Dioscoreae 11.4%, Rhizoma Imperatae 11.4%, Endothelium Corneum Gigeriae Galli 5.6%, Herba Taraxaci 5.6%, Fructus Mume 5.6%, Fructus Lycii 5.6%.