CN103356922A - Traditional Chinese medicine granule used for treating liver and gallbladder damp-heat icterus - Google Patents

Abstract

The invention discloses a traditional Chinese medicine granule used for treating liver and gallbladder damp-heat icterus, and relates to a traditional Chinese medicine preparation. The traditional Chinese medicine granule is characterized by being prepared from the following raw traditional Chinese medicines in percentage by weight: 10.2 to 12.5% of capillary Artemisia, 3.3 to 4.1% of coptis chinensis, 1.9 to 2.4% of ginger processed pinellia, 10.2 to 12.5% of trichosanthes kirilowii Maxim, 3.3 to 4.1% of immature bitter orange, 5.0 to 6.2% of cortex magnoliae officinalis, 5.0 to 6.2% of poria cocos, 5.0 to 6.2% of semen coicis, 5.0 to 6.2% of white hyacinth Bean, 10.2 to 12.5% of rhizoma dioscoreae, 10.2 to 12.5% of rhizoma imperatae, 5.0 to 6.2% of endothelium corneum gigeriae galli, 5.0 to 6.2% of dandelion, 5.0 to 6.2% of dark plum, and 5.0 to 6.2% of lycium chinense. The traditional Chinese medicine granule is convenient to take, high in pointing to symtoms, fast to come into effect, and good in treatment effect, and has the recovery rate of 88.8% and effective rate of 100%.

Description

A kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice

Technical field

The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice.

Background technology

The damp and hot pathogenic factor of jaundice system impression, the retardance liver and gall, mechanism of qi is obstructed, and catharsis is not normal, due to bile is excessive.Disease take icteric sclera, yellowish body, yellow urine as main clinical manifestation.Be more common in hepatobiliary system disease.Clinical manifestation is: skin, sclera etc. is organized xanthochromia, and when jaundice was deepened, urine, expectorant, tear and perspiration were also by xanthochromia; The color change of urine and excrement; With abdominal distention, stomachache, inappetence, feel sick, vomiting, diarrhea or constipation; Or loss of appetite, feel sick, detest the symptoms such as greasy, fatigue and weak, yellowish urine such as tea, hepatalgia, heating, oliguria.Doctor trained in Western medicine is thought: the reason that causes jaundice is: or the hematoclasis increase, bilirubin generates too much; Or liver cell lesion to cause bilirubin metabolism not normal; Or the inside and outside biliary system generation of liver mechanical obstruction, affect bilirubinic drainage; Or hepatocyte has some birth defect, can not finish bilirubinic homergy.Symptomatic therapy is taked in treatment, and oral medicine commonly used has prednisone, methotrexate, ciclosporin etc.; In addition, implement the method treatments such as blood transfusion, drain according to the state of an illness.The Therapeutic Method of doctor trained in Western medicine is to take stopgap measures, and can not to patient's internal organs comprehensively regulating, effect a permanent cure far away from the traditional Chinese medical science.The traditional Chinese medical science is thought: the basic pathogenesis of jaundice is the turbid damp retardance.Or the diseases caused by exogenous pathogenic factor turbid damp, damp and hot, epidemic disease is malicious etc., and seasonal pathogen enters from mouth, pents up in middle Jiao, transporting and transforming function of the spleen and stomach is not normal, damp and hot fumigating in taste involved liver and gall; Or injury due to diet irregular diet or be addicted to drink excessively, all can impairing the spleen and stomach, so that the transportation capabilities dereliction of duty, endogenous damp formation, stifling or block in the taste liver and gall; Or plain body body weakness of the spleen and stomach, overstrain, damage of the spleen loses fortune, deficiency of qi and blood, the liver failing to be nourished of a specified duration.It is not normal to cause suffocating of liver and gall, and bile overflows and jaundice occurs.In treatment, the traditional Chinese medical science is particular about determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, so, abide by the medical knowledge of the traditional Chinese medical science, the medicine that development minute disease type is treated jaundice is very necessary.

Summary of the invention

The object of the present invention is to provide a kind of disease type for the treatment of, suiting the medicine to the illness property is strong, and produce effects is fast, and therapeutic effect is good, a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice of this of taking convenience.

In order to reach above purpose, the technical solution used in the present invention is: this a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice is characterized in that: it is to be made by the raw material of Chinese medicine of following percentage by weight: Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, Fructus Lycii 5.0-6.2%; Wherein each raw material of Chinese medicine constituent content percent sum equals 100%.Optimizing prescription is: Herba Artemisiae Scopariae 11.4%, Rhizoma Coptidis 3.7%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2%, Fructus Trichosanthis 11.4%, Fructus Aurantii Immaturus 3.7%, Cortex Magnoliae Officinalis 5.6%, Poria 5.6%, Semen Coicis 5.6%, Semen Lablab Album 5.6%, Rhizoma Dioscoreae 11.4%, Rhizoma Imperatae 11.4%, Endothelium Corneum Gigeriae Galli 5.6%, Herba Taraxaci 5.6%, Fructus Mume 5.6%, Fructus Lycii 5.6%.This a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice, made by following steps: one, by Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, the ratio of Fructus Lycii 5.0-6.2% accurately takes by weighing each raw material of Chinese medicine that cooks, former in taking by weighing each during spice, with the raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae is mixed puts together, Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis is mixed puts Rhizoma Coptidis together, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii is mixed puts together; Two, will weigh up under the temperature that mixed raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae of putting place drying baker 70-80 ℃ dry 24 hours, be down to natural temperature, be ground into the Chinese medicine fine powder of 60 mesh sieves, for subsequent use; Three, will weigh up mixed raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis of putting and put into multifunctional extracting pot, add domestic water, stir, the amount that adds water is alleged Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis quality sum 7-8 times, soaked 20 minutes, volatile oil is carried in heating, and the time of carrying is 60 minutes, carries complete, it is for subsequent use to take off volatile oil cold preservation, medicine liquid mixture in the multifunctional extracting pot is filtered, stay slag, get filtering liquid medicine; Four, will weigh up mixed raw material of Chinese medicine Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii of putting and put into medicine boiler, add domestic water, stir, the amount that adds water is alleged Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 5-6 times, soaks 30 minutes, intense fire is heated to and boils, changed slow fire boiling 60 minutes, stopped heating filters, stay slag, get medicinal liquid one time; Five, incorporate the medicinal residues in the multifunctional extracting pot into medicine boiler, add domestic water, stir, amount of water is alleged raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Coptidis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Fructus Trichosanthis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 4-5 times, and intense fire is heated to and boils, changed slow fire boiling 60 minutes, stopped heating filters, and gets the secondary medicinal residues, the squeezing medicinal residues get the squeezing medicinal residues; Six, all incorporate filtering liquid medicine, medicinal liquid, secondary medicinal liquid, a squeezing medicinal liquid into stainless steel cylinder, get admixing medical solutions, in admixing medical solutions, add chitin, stir evenly, the addition of chitin is that 3/0,000,45 ℃ of admixing medical solutions quality are incubated 10 hours, get supernatant liquid filtering, waste gets the purification medicinal liquid; Seven, will purify medicinal liquid and add medicine boiler, heating is concentrated, and being concentrated into relative density is 1.30～1.35, stopped heating, and cooling gets the Chinese medicine thick paste naturally; Eight, add mixing fine powders for subsequent use in the Chinese medicine thick paste, mix thoroughly, then add edible ethanol, the addition of edible ethanol is 1/5～1/4 of mixing fine powders quality, and mixing is softening, makes the Chinese medicine wet granular by 12 mesh sieves of granulation machine; Nine, the Chinese medicine wet granular is put into drip pan, place 60-80 ℃ of drying in the baking oven, do when being lower than 2% to moisture, stopped heating is lowered the temperature naturally, gets the dried granule of Chinese medicine; Ten, the dried granule stranding of Chinese medicine is broken, volatile oil is evenly sprayed on it, to mix thoroughly, airtight placement absorbed volatile oil in 48 hours, pack, sealing, every bag of 10g is a kind of Chinese medicinal granule finished product for the treatment of the liver gallbladder damp-heat type jaundice.

This a kind of prescription pharmacology for the treatment of the Chinese medicinal granule of liver gallbladder damp-heat type jaundice is: heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting, dampness removing jaundice eliminating, invigorating the spleen and regulating the stomach, nourishing the liver and kidney.

Wherein, Herba Artemisiae Scopariae bitter in the mouth, suffering, cold nature; Return spleen, stomach, liver, gallbladder meridian.Has clearing away heat-damp and promoting diuresis, the effect of jaundice eliminating.Cure mainly jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis etc.; Pharmaceutical research proof Herba Artemisiae Scopariae has function of gallbladder promoting, and liver function protecting is analgesic, antiinflammatory, blood fat reducing, the effects such as coronary dilating.

The Rhizoma Coptidis bitter in the mouth, cold in nature; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache.

The Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) acrid in the mouth, warm in nature; Return spleen, stomach, lung meridian.Have warming middle-JIAO and reduce phlegm, the effect of stopping nausea and vomiting by lowering the adverse flow of QI.Cure mainly vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.

Fructus Trichosanthis sweetness and bitterness, cold in nature; Return lung, stomach, large intestine channel.Have lung moistening, reduce phlegm, eliminating stagnation, the effect of intestine moistening.Cure mainly phlegm-heat cough, the thoracic obstruction, blocked-up chest, the consumptive lung disease hemoptysis is quenched one's thirst, jaundice, constipation, carbuncle from the beginning of.

Fructus Aurantii Immaturus bitter in the mouth, suffering, cold in nature.Return spleen, stomach, liver, heart channel.Cure mainly and stop in stagnant, the feeling of fullness distending pain, constipation, heavy behind the dysentery, blocked-up chest, gastroptosis, uterine prolapse, proctoptosis.Pharmacological research: Fructus Aurantii Immaturus has diuresis.

Cortex Magnoliae Officinalis bitter in the mouth, suffering, warm in nature; Return spleen, stomach, large intestine channel.Have the circulation of qi promoting removing food stagnancy, dampness is except expiring the effect of lowering the adverse QI to relieve asthma; Cure mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough.

Poria sweet in the mouth, light, property is flat; GUIXIN warp, lung meridian, spleen channel, kidney channel.Effect with promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful.

The Semen Coicis slightly sweet flavor, cool in nature; Return spleen, stomach, lung meridian.Function with spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, diuretic.Semen Coicis property is partially cold and cool, is longer than promoting diuresis to eliminate damp pathogen, clearing away heat and discharging pus, and the eliminating impediment pain relieving is usually used in dysuria, edema, beriberi, lung abscess, acute appendicitis, rheumatic arthralgia, muscle arteries and veins contraction urgency and damp-warm diseases are at edema caused by disorder of QI.

The Semen Lablab Album slightly sweet flavor, property is flat; Return spleen channel, stomach warp.Has spleen invigorating, removing dampness, the effect of relieving summer heat.Cure mainly: insufficiency of the spleen resulting in production of dampness, anorexia and loose stool, leukorrhagia, heat-damp in summer is vomited and diarrhoea, and excessive thirst is uncomfortable in chest.

The Rhizoma Dioscoreae sweet in the mouth, property is flat; Return spleen, lung, kidney channel.Has the spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the effect of the kidney invigorating arresting seminal emission.Cure mainly insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.

Rhizoma Imperatae sweet in the mouth, cold in nature; Return lung, stomach, small intestine meridian.Has removing heat from blood, hemostasis, heat clearing away, the effect of diuresis.Cure mainly the calentura excessive thirst, spit blood epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.

The Endothelium Corneum Gigeriae Galli sweet in the mouth, cold in nature; Return spleen, stomach, small intestinal, urinary bladder channel.Has promoting digestion and invigorating the stomach, the effect of arresting seminal emission.

Herba Taraxaci sweet in the mouth, little hardship, cold in nature.Return spleen, stomach, kidney three warps.Has heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation.Cure mainly upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis is controlled acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.

Fructus Mume sour in the mouth, puckery, property is flat; Return liver, spleen, lung, large intestine channel.Have promote the production of body fluid, quench the thirst, astringe the lung, the effect of astringing intestine to stop diarrhea, relieving colic caused by ascaris worm, cure mainly chronic cough of deficiency lung, the deficiency-heat excessive thirst, chronic malaria, chronic diarrhea, dysentery is had blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis.Studies show that: the malic acid in the Fructus Mume can be guided to large intestine to an amount of moisture, forms feces and excretes, with appetite stimulator.

The Fructus Lycii sweet in the mouth, property is flat; Return liver, kidney, lung meridian.Has nourishing the liver and kidney, the effect of replenishing vital essence to improve eyesight.Cure mainly chronic consumptive disease damage of essence, soreness of waist and knee joint; Vertigo and tinnitus, thirsty, the blood deficiency and yellow complexion of interior-heat Xiao, blurred vision is not clear.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual deterioration; Soreness of the waist and knees; Seminal emission is quenched one's thirst; Cough due to consumptive disease.

This a kind of instructions of taking for the treatment of the Chinese medicinal granule of liver gallbladder damp-heat type jaundice: after meal half an hour warm boiled water, early, the evening each once, be grown up each 2 bags, child's dosing is cut down according to the circumstance.20 days is a course for the treatment of.

Taboo: period in a medicine is avoided living, cold, zest and delicious food savoury.The careful usefulness of anemia of pregnant woman.

Beneficial effect of the present invention is: a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice is provided, and this Chinese medicinal granule taking convenience, suiting the medicine to the illness property is strong, and produce effects is fast, and therapeutic effect is good, and cure rate is 88.8%, effective percentage 100%.

Analysis of clinical

One, diagnosis basis

Formulate according to the jaundice dampness-heat in the liver and gallbladder disease type diagnostic criteria that " People's Republic of China's Chinese medicine industry standard (disease of tcm Standardization of diagnosis and curative effect) " (ZY/T001.1-94) stipulated:

1, yellow skin and eye is yellow distinct.It is thirsty to generate heat, regretful Nang in the heart, xerostomia and covering with mat, the tending to vomit of feeling sick, abdominal distention hypochondriac pain, constipation or be canescence, oliguria with yellow urine.

2, red tongue, yellow and greasy fur, wiry and frequent pulse.

3, eating and drinking without temperance is arranged, the medical histories such as hepatitis contact or applied chemistry goods medicine.

4, liver, spleen or gallbladder enlargement are with tenderness or tenderness.

Two, criterion of therapeutical effect

Formulate according to the jaundice liver criterion of therapeutical effect that " People's Republic of China's Chinese medicine industry standard (disease of tcm Standardization of diagnosis and curative effect) " (ZY/T001.1-94) stipulated:

1, cure: jaundice disappears, other transference cures, and lab index is normal.

2, take a turn for the better: jaundice and other sx↓s, bilirubin is normal or reduce other lab index improvements.

3, do not heal: jaundice is not moved back or is deepened, and other symptoms and lab index are without improvement.

Three, therapeutic effect analysis

From in January, 2011 to 2012 year December, make a definite diagnosis altogether liver gallbladder damp-heat type Patients with Jaundice 125 examples, male patient's 89 examples wherein, female patient 36 examples, oldest 81 years old, minimum 9 years old, take this a kind of 2～3 courses for the treatment of of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice, cure 111 examples, cure rate 88.8%, 14 examples that take a turn for the better, effective percentage 100%.

Specific embodiment

Embodiment 1

By Herba Artemisiae Scopariae 11.4%, Rhizoma Coptidis 3.7%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2%, Fructus Trichosanthis 11.4%, Fructus Aurantii Immaturus 3.7%, Cortex Magnoliae Officinalis 5.6%, Poria 5.6%, Semen Coicis 5.6%, Semen Lablab Album 5.6%, Rhizoma Dioscoreae 11.4%, Rhizoma Imperatae 11.4%, Endothelium Corneum Gigeriae Galli 5.6%, Herba Taraxaci 5.6%, Fructus Mume 5.6%, the ratio of Fructus Lycii 5.6% accurately takes by weighing each the raw material of Chinese medicine 100kg that cooks, wherein, Herba Artemisiae Scopariae 11.4kg, Rhizoma Coptidis 3.7kg, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2kg, Fructus Trichosanthis 11.4kg, Fructus Aurantii Immaturus 3.7kg, Cortex Magnoliae Officinalis 5.6kg, Poria 5.6kg, Semen Coicis 5.6kg, Semen Lablab Album 5.6kg, Rhizoma Dioscoreae 11.4kg, Rhizoma Imperatae 11.4kg, Endothelium Corneum Gigeriae Galli 5.6kg, Herba Taraxaci 5.6kg, Fructus Mume 5.6kg, Fructus Lycii 5.6kg; Former in taking by weighing each during spice, raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae are mixed and put together, Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis are mixed and are put together, and Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii mix and put together; With weighing up mixed raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae of putting and place under drying baker 70-80 ℃ the temperature dry 24 hours, be down to natural temperature, be ground into the Chinese medicine fine powder of 60 mesh sieves, for subsequent use; Put into multifunctional extracting pot with weighing up mixed raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis of putting, add domestic water 150kg, stir, soaked 20 minutes, volatile oil is carried in heating, the time of carrying is 60 minutes, carry completely, it is for subsequent use to take off volatile oil cold preservation, and the medicine liquid mixture in the multifunctional extracting pot is filtered, stay slag, get filtering liquid medicine; Put into medicine boiler with weighing up mixed raw material of Chinese medicine Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii of putting, add domestic water 340kg, stir, soaked 30 minutes, intense fire is heated to and boils, and changes slow fire boiling 60 minutes, stopped heating, filter, stay slag, get medicinal liquid one time; Incorporate the medicinal residues in the multifunctional extracting pot into medicine boiler, add domestic water 350kg, stir, intense fire is heated to and boils, and changes slow fire boiling 60 minutes, and stopped heating filters, and gets the secondary medicinal residues, and the squeezing medicinal residues get the squeezing medicinal residues; Six, all incorporate filtering liquid medicine, medicinal liquid, secondary medicinal liquid, a squeezing medicinal liquid into stainless steel cylinder, get admixing medical solutions, in admixing medical solutions, add chitin, stir evenly, the addition of chitin is that 3/0,000,45 ℃ of admixing medical solutions quality are incubated 10 hours, get supernatant liquid filtering, waste gets the purification medicinal liquid; Seven, will purify medicinal liquid and add medicine boiler, heating is concentrated, and being concentrated into relative density is 1.30～1.35, stopped heating, and cooling gets the Chinese medicine thick paste naturally; Eight, add mixing fine powders for subsequent use in the Chinese medicine thick paste, mix thoroughly, then add edible ethanol, the addition of edible ethanol is 1/5～1/4 of mixing fine powders quality, and mixing is softening, makes the Chinese medicine wet granular by 12 mesh sieves of granulation machine; Nine, the Chinese medicine wet granular is put into drip pan, place 60-80 ℃ of drying in the baking oven, do when being lower than 2% to moisture, stopped heating is lowered the temperature naturally, gets the dried granule 30.1kg of Chinese medicine; Ten, the dried granule stranding of Chinese medicine is broken, volatile oil is evenly sprayed on it, to mix thoroughly, airtight placement absorbed volatile oil in 48 hours, pack, sealing, every bag of 10g is a kind of Chinese medicinal granule finished product for the treatment of the liver gallbladder damp-heat type jaundice.

With these a kind of Chinese medicinal granule treatment dampness-heat in the liver and gallbladder patient 44 examples for the treatment of the liver gallbladder damp-heat type jaundice, cure 40 examples, cure rate 90.9%; 4 examples that take a turn for the better, improvement rate 9.1%; Effective percentage 100%.

Model case

The Wei * *, man, 46 years old, Laiwu City Gangcheng District Yan Zhuan town peasant.On June 11st, 2011 is to our hospital.The main suit: before 10 days without inducement malaise appearred, inappetence, the tending to vomit of sometimes feeling sick, icteric sclera, yellowish body, yellowish urine appear in activity postemphasis then, accompany upper right abdomen dull pain uncomfortable, and without diarrhoea, without heating, without nervous uncomfortable in chest, no headache is dizzy, and it is poor that sleep night.Treat by " gastritis " medication at this village's clinic after the morbidity, the state of an illness is examined out of admiration for a famous person without improvement.Examine and see: shallow complexion, the whole skin xanthochromia, the obvious xanthochromia of sclera, upper right abdominal pressure pain, pain is kowtowed in the hepatic region; Red tongue, yellow and greasy fur, stringy pulse.Look into liver function and show glutamate pyruvate transaminase 261U/L, GOT2 11U/L, total bilirubin 180.6umol/L, blood fat, blood glucose and routine blood test result are normal, and color ultrasound is shown liver parenchyma lesion, and the electrocardiogram result is normal.Be diagnosed as the liver gallbladder damp-heat type jaundice, take this Chinese medicinal granule treatment, subjective symptoms alleviates after the course for the treatment of, and liver function takes a turn for the better, and total bilirubin is down to 60.36umol/L; General malaise transference cure after two courses for the treatment of, the check liver function recovery is normal, and total bilirubin is down to 13.6umol/L; Adhere to again taking course for the treatment of of this Chinese medicinal granule after leaving hospital, follow up a case by regular visits to 1 year without recurrence.

Embodiment 2

By Herba Artemisiae Scopariae 11.5%, Rhizoma Coptidis 3.5%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.0%, Fructus Trichosanthis 11.0%, Fructus Aurantii Immaturus 3.5%, Cortex Magnoliae Officinalis 5.5%, Poria 5.5%, Semen Coicis 5.5%, Semen Lablab Album 5.5%, Rhizoma Dioscoreae 11.0%, Rhizoma Imperatae 11.5%, Endothelium Corneum Gigeriae Galli 6.0%, Herba Taraxaci 6.0%, Fructus Mume 6.0%, the ratio of Fructus Lycii 6.0% accurately takes by weighing each the raw material of Chinese medicine 100kg that cooks, wherein, Herba Artemisiae Scopariae 11.5kg, Rhizoma Coptidis 3.5kg, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2kg, Fructus Trichosanthis 11kg, Fructus Aurantii Immaturus 3.5kg, Cortex Magnoliae Officinalis 5.5kg, Poria 5.5kg, Semen Coicis 5.5kg, Semen Lablab Album 5.5kg, Rhizoma Dioscoreae 11kg, Rhizoma Imperatae 11.5kg, Endothelium Corneum Gigeriae Galli 6kg, Herba Taraxaci 6kg, Fructus Mume 6kg, Fructus Lycii 6kg.

Manufacture method is with embodiment 1.

With these a kind of Chinese medicinal granule treatment dampness-heat in the liver and gallbladder patient 40 examples for the treatment of the liver gallbladder damp-heat type jaundice, cure 35 examples, cure rate 87.5%; 5 examples that take a turn for the better, improvement rate 12.5%; Effective percentage 100%.

Model case

Lee * *, man, 63 years old, Laiwu City Laicheng district teacher.December in 2011 6 days is because of weak, poor appetite 3 years, increases the weight of to accompany icteric sclera, yellowish urine 7 days to our hospital.Main suit: malaise occurred without inducement before 3 years, the activity postemphasis, inappetence, sometimes the tending to vomit of feeling sick, and upper right abdomen dull pain is diagnosed as " chronic hepatitis B " in the court, and sb.'s illness took a favorable turn in more than 20 days to give the Drug therapys such as hepatoprotective antiinflammatory, antiviral in hospital, long-term taking antiviral drugs over 3 years is interrupted and is taken liver-protecting medicine.Weak without the inducement appearance before 7 days, poor appetite increases the weight of, companion's icteric sclera, yellowish urine, and upper right abdomen dull pain is uncomfortable, without diarrhoea, the nothing heating, without nervous uncomfortable in chest, no headache is dizzy, and night, dormancy was poor.Do not take notice of at that time after the morbidity, but the state of an illness gradually increases the weight of, satisfy to examine.Examine and see: dim complexion, the whole skin xanthochromia, the obvious xanthochromia of sclera, upper right abdominal pressure pain, pain is kowtowed in the hepatic region; Red tongue, yellow and greasy fur, stringy pulse.Look into liver function and show glutamate pyruvate transaminase 169U/L, glutamate-oxaloacetate transaminase 01U/L, total bilirubin 158.6umol/L, blood fat, blood glucose and routine blood test result are normal, and color ultrasound is shown liver parenchyma lesion, and the electrocardiogram result is normal.Be diagnosed as the liver gallbladder damp-heat type jaundice, take this Chinese medicinal granule treatment, subjective symptoms alleviates after the course for the treatment of, and liver function takes a turn for the better, and total bilirubin is down to 80.36umol/L; The general malaise symptom is obviously improved after two courses for the treatment of, looks into liver function and shows glutamate pyruvate transaminase 79U/L, glutamic oxaloacetic transaminase, GOT 71U/L, and total bilirubin is down to 31.6umol/L; Subjective symptoms disappears after three courses for the treatment of, and liver function recovery is normal, and total bilirubin is down to normally, follows up a case by regular visits to 1 year without recurrence.

Embodiment 3

By Herba Artemisiae Scopariae 12.0%, Rhizoma Coptidis 4.0%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.0%, Fructus Trichosanthis 10.5%, Fructus Aurantii Immaturus 4.0%, Cortex Magnoliae Officinalis 6.0%, Poria 6.0%, Semen Coicis 6.0%, Semen Lablab Album 6.0%, Rhizoma Dioscoreae 10.5%, Rhizoma Imperatae 11.0%, Endothelium Corneum Gigeriae Galli 5.5%, Herba Taraxaci 5.5%, Fructus Mume 5.5%, the ratio of Fructus Lycii 5.5% accurately takes by weighing each the raw material of Chinese medicine 100kg that cooks, wherein, Herba Artemisiae Scopariae 12kg, Rhizoma Coptidis 4kg, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2kg, Fructus Trichosanthis 10.5kg, Fructus Aurantii Immaturus 4kg, Cortex Magnoliae Officinalis 6kg, Poria 6kg, Semen Coicis 6kg, Semen Lablab Album 6kg, Rhizoma Dioscoreae 10.5kg, Rhizoma Imperatae 11kg, Endothelium Corneum Gigeriae Galli 5.5kg, Herba Taraxaci 5.5kg, Fructus Mume 5.5kg, Fructus Lycii 5.5kg.

Manufacture method is with embodiment 1.

With these a kind of Chinese medicinal granule treatment dampness-heat in the liver and gallbladder patient 41 examples for the treatment of the liver gallbladder damp-heat type jaundice, cure 36 examples, cure rate 87.8%; 5 examples that take a turn for the better, improvement rate 12.2%; Effective percentage 100%.

Model case

Qi * *, woman, 38 years old, Laiwu City Laicheng district worker.On February 10th, 2012 is to our hospital because of weak, poor appetite icteric sclera, yellowish urine more than 10 days.The main suit: took continuously a kind of hair growth medicine 2 months, and malaise occurred without inducement before 10 days, inappetence is felt sick sometimes, and upper right abdomen dull pain is uncomfortable, icteric sclera, yellowish body, yellowish urine then occur, without diarrhoea, without heating, without dysurea, frequent micturition, no headache is dizzy, and it is poor that sleep night.Medical at that time after the morbidity, think due to the fatigue, but the state of an illness gradually increases the weight of, examine out of admiration for a famous person.Examine and see: spirit is poor, and yellow complexion, whole skin xanthochromia, the obvious xanthochromia of sclera, heart and lung auscultation be without unusually, upper right abdominal pressure pain, and about 2cm under the liver rib, tenderness, kowtow bitterly the hepatic region, two lower limb Mild edema; Red tongue, yellow and greasy fur, wiry and frequent pulse.Look into liver function and show glutamate pyruvate transaminase 399U/L, glutamic oxaloacetic transaminase, GOT 301U/L, total bilirubin 178.1umol/L, blood fat, blood glucose and routine blood test result are normal, and color ultrasound is shown liver parenchyma lesion.Be diagnosed as the liver gallbladder damp-heat type jaundice, take this Chinese medicinal granule treatment, subjective symptoms alleviates after the course for the treatment of, and liver function takes a turn for the better, and total bilirubin is down to 90.3umol/L; The general malaise symptom is obviously improved after two courses for the treatment of, looks into liver function and shows glutamate pyruvate transaminase 68U/L, glutamic oxaloacetic transaminase, GOT 71U/L, and total bilirubin is down to 41.3umol/L; Subjective symptoms disappears after three courses for the treatment of, and liver function recovery is normal, and total bilirubin is down to normally, follows up a case by regular visits to 1 year without recurrence.

Claims (3)

1. Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice, it is characterized in that: it is to be made by the raw material of Chinese medicine of following percentage by weight: Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, Fructus Lycii 5.0-6.2%; Wherein each raw material of Chinese medicine constituent content percent sum equals 100%.

2. a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice according to claim 1, it is characterized in that: made by following steps: one, by Herba Artemisiae Scopariae 10.2-12.5%, Rhizoma Coptidis 3.3-4.1%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 1.9-2.4, Fructus Trichosanthis 10.2-12.5%, Fructus Aurantii Immaturus 3.3-4.1%, Cortex Magnoliae Officinalis 5.0-6.2%, Poria 5.0-6.2%, Semen Coicis 5.0-6.2%, Semen Lablab Album 5.0-6.2%, Rhizoma Dioscoreae 10.2-12.5%, Rhizoma Imperatae 10.2-12.5%, Endothelium Corneum Gigeriae Galli 5.0-6.2%, Herba Taraxaci 5.0-6.2%, Fructus Mume 5.0-6.2%, the ratio of Fructus Lycii 5.0-6.2% accurately takes by weighing each raw material of Chinese medicine that cooks, former in taking by weighing each during spice, with the raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae is mixed puts together, Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis is mixed puts Rhizoma Coptidis together, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii is mixed puts together; Two, will weigh up under the temperature that mixed raw material of Chinese medicine Poria, Semen Coicis, Rhizoma Dioscoreae of putting place drying baker 70-80 ℃ dry 24 hours, be down to natural temperature, be ground into the Chinese medicine fine powder of 60 mesh sieves, for subsequent use; Three, will weigh up mixed raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis of putting and put into multifunctional extracting pot, add domestic water, stir, the amount that adds water is alleged Herba Artemisiae Scopariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Cortex Magnoliae Officinalis quality sum 7-8 times, soaked 20 minutes, volatile oil is carried in heating, and the time of carrying is 60 minutes, carries complete, it is for subsequent use to take off volatile oil cold preservation, medicine liquid mixture in the multifunctional extracting pot is filtered, stay slag, get filtering liquid medicine; Four, will weigh up mixed raw material of Chinese medicine Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii of putting and put into medicine boiler, add domestic water, stir, the amount that adds water is alleged Rhizoma Coptidis, Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 5-6 times, soaks 30 minutes, intense fire is heated to and boils, changed slow fire boiling 60 minutes, stopped heating filters, stay slag, get medicinal liquid one time; Five, incorporate the medicinal residues in the multifunctional extracting pot into medicine boiler, add domestic water, stir, amount of water is alleged raw material of Chinese medicine Herba Artemisiae Scopariae, Rhizoma Coptidis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Fructus Trichosanthis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Semen Lablab Album, Rhizoma Imperatae, Endothelium Corneum Gigeriae Galli, Herba Taraxaci, Fructus Mume, Fructus Lycii quality sum 4-5 times, and intense fire is heated to and boils, changed slow fire boiling 60 minutes, stopped heating filters, and gets the secondary medicinal residues, the squeezing medicinal residues get the squeezing medicinal residues; Six, all incorporate filtering liquid medicine, medicinal liquid, secondary medicinal liquid, a squeezing medicinal liquid into stainless steel cylinder, get admixing medical solutions, in admixing medical solutions, add chitin, stir evenly, the addition of chitin is that 3/0,000,45 ℃ of admixing medical solutions quality are incubated 10 hours, get supernatant liquid filtering, waste gets the purification medicinal liquid; Seven, will purify medicinal liquid and add medicine boiler, heating is concentrated, and being concentrated into relative density is 1.30～1.35, stopped heating, and cooling gets the Chinese medicine thick paste naturally; Eight, add mixing fine powders for subsequent use in the Chinese medicine thick paste, mix thoroughly, then add edible ethanol, the addition of edible ethanol is 1/5～1/4 of mixing fine powders quality, and mixing is softening, makes the Chinese medicine wet granular by 12 mesh sieves of granulation machine; Nine, the Chinese medicine wet granular is put into drip pan, place 60-80 ℃ of drying in the baking oven, do when being lower than 2% to moisture, stopped heating is lowered the temperature naturally, gets the dried granule of Chinese medicine; Ten, the dried granule stranding of Chinese medicine is broken, volatile oil is evenly sprayed on it, to mix thoroughly, airtight placement absorbed volatile oil in 48 hours, pack, sealing, every bag of 10g is a kind of Chinese medicinal granule finished product for the treatment of the liver gallbladder damp-heat type jaundice.

3. a kind of Chinese medicinal granule for the treatment of the liver gallbladder damp-heat type jaundice according to claim 1 is characterized in that: optimizing prescription is: Herba Artemisiae Scopariae 11.4%, Rhizoma Coptidis 3.7%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 2.2%, Fructus Trichosanthis 11.4%, Fructus Aurantii Immaturus 3.7%, Cortex Magnoliae Officinalis 5.6%, Poria 5.6%, Semen Coicis 5.6%, Semen Lablab Album 5.6%, Rhizoma Dioscoreae 11.4%, Rhizoma Imperatae 11.4%, Endothelium Corneum Gigeriae Galli 5.6%, Herba Taraxaci 5.6%, Fructus Mume 5.6%, Fructus Lycii 5.6%.