CN105816515A - Composition for dispelling effect of alcohol and protecting liver - Google Patents
Composition for dispelling effect of alcohol and protecting liver Download PDFInfo
- Publication number
- CN105816515A CN105816515A CN201610347391.3A CN201610347391A CN105816515A CN 105816515 A CN105816515 A CN 105816515A CN 201610347391 A CN201610347391 A CN 201610347391A CN 105816515 A CN105816515 A CN 105816515A
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- Prior art keywords
- liver
- effect
- radix puerariae
- herba lysimachiae
- composition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention belongs to the field of healthcare food and provides a composition for dispelling the effect of alcohol and protecting the liver .The composition is composed of a main material and auxiliary materials .The main material is extract of the root of kudzu vines and penthorum chinense pursh .By mass, the extract of the root of kudzu vines and penthorum chinense pursh accounts for 20-40% of the total weight of 100% of the product; the auxiliary materials comprise 40-60% of sucrose, 4.5-15% of honey, 4-8% of milk powder, 0-0.3% of sodium citrate, 0-0.3% of citric acid, 0-3.4% of malic acid, 0-10% of starch and 0-0.5% of talcum powder .The composition overcomes the defects that raw material composition of an existing product for dispelling the effect of the alcohol is complex, the production process is complex, and the effect of dispelling the effect of the alcohol is not remarkable, the raw material composition of the composition for dispelling the effect of alcohol and protecting the liver are simple, the process is simple and easy to implement, and the effect of dispelling the effect of alcohol and protecting the liver is obvious.
Description
Technical field
The invention belongs to field of health care food, be specifically related to a kind of Soboring-up liver-protecting compositions.
Background technology
People in daily life, are frequently encountered by the situation of insobriety.In order to alleviate the sense of discomfort that insobriety brings, it is developed multiple relieving alcoholic intoxication product.But, these relieving alcoholic intoxication products materials composition complexity, complex production process, sober up effect is the most notable.
Summary of the invention
It is an object of the invention to overcome existing relieving alcoholic intoxication products material composition complexity, complex production process, the inapparent defect of sober up effect, provide a kind of raw material composition simple for people, simple process is easy, effect obvious Soboring-up liver-protecting compositions of relieving alcoholism and protecting the liver.
It is an object of the invention to be achieved through the following technical solutions:
The Soboring-up liver-protecting compositions of the present invention, is made up of major ingredient and adjuvant, it is characterised in that major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, and by percentage to the quality, product gross weight is 100%, and Radix Puerariae and Herba Lysimachiae Clethroids extract are 20%~40%;Adjuvant is the sucrose of 40%~60%, the Mel of 4.5%~15%, the milk powder of 4%~8%, 0~the sodium citrate of 0.3%, 0~the citric acid of 0.3%, 0~the malic acid of 3.4%, 0~the starch of 10%, 0~the Pulvis Talci of 0.5%.
In such scheme, described Soboring-up liver-protecting compositions, its preparation method is as follows:
By Radix puerariae root and dry Herba Lysimachiae Clethroids, through cleaning, after cutting, by Radix puerariae root: dry Herba Lysimachiae Clethroids=1: the part by weight of 0.5~2 compounds, and must compound material.Extracting in water, during extraction, adds water by 8~10 times of multiple ingredients by weight, and normal pressure boils 1~1.5 hour, filters, and filtering residue extracts again, extracts 2~3 times altogether;Merging filtrate, concentrates, and concentrated solution adds 95% ethanol, is 60% to ethanol content, stirs, and stands 4~8 hours, filters;Filtrate heating recovery ethanol, concentrates, and measures solid content, adds adjuvant, mixing granulation or film-making, weight packaging by formula, obtains finished product.
The present invention, with Radix Puerariae, Herba Lysimachiae Clethroids as main material, carries through water, alcohol extraction, and extracting solution is mainly composed of Flavonoid substances, is equipped with adjuvant and makes electuary or tablet, has obvious relieving alcoholic intoxication, liver tonifying and protecting effects.
The Soboring-up liver-protecting compositions of the present invention has the liver protecting, eliminates uncomfortable after drinking, appetite stimulator, and sunstroke prevention is promoted the production of body fluid, effect of refreshment.
Radix Puerariae is the tuber of leguminous plant Pueraria lobota, containing a large amount of isoflavonoid derivatives.Radix Puerariae total flavones has coronary artery dilator, promotes coronary artery blood flow and reduce the effects such as myocardial oxygen consumption.Herba Lysimachiae Clethroids is saxifragaceae plant Herba Lysimachiae Clethroids herb, has another name called Penthorum chinense, Herba Penthori chinensis, Radix Homonoiae Ripariae, also contains flavones ingredient material.Radix Puerariae and Herba Lysimachiae Clethroids are edible plants.
Through multiple formula test, compare, inventor finds, Radix Puerariae is compatible with Herba Lysimachiae Clethroids, has a following effect unique:
A, Radix Puerariae return spleen, stomach two warp, invigorating spleen and reinforcing stomach, promoting the production of body fluid to quench thirst, and alcohol user's digestive tract is had good protective effect;Herba Lysimachiae Clethroids returns liver, gallbladder two warp, has effect of hepatoprotective function of gallbladder promoting, reducing enzyme and treating jaundice.So, Radix Puerariae is compatible with Herba Lysimachiae Clethroids, and its effect can hold up soil to press down wood, suppressing the hyperactive liver nourishing the stomach with superposition, complementation, enhances the effect of relieving alcoholic intoxication removing toxic substances, and effect of relieving alcoholism and protecting the liver is obvious.
B, Radix Puerariae are compatible with Herba Lysimachiae Clethroids, and its effective ingredient character is close, are conducive at that same temperature, utilize identical solvent to realize higher extraction ratio, and production technology is relatively simple.
And existing relieving alcoholic intoxication product uses the combination of many herbal medicines, although meeting the principle of Chinese medicine " monarch ", but it is low to result in effective ingredient in formula, and be prone in extraction produce precipitation and muddiness, it is difficult to carry out high efficiency extraction in identical temperature and solvent, due to formula and technologic defect, product effective ingredient is low, it is impossible to obtain significant sober up effect.The present invention then breaches " monarch " principle, only with two taste principal agents, in product, contained flavones ingredient is apparently higher than the product of other many herbal medicines, does not only result in production technology easy, achieve higher effective component extraction rate, it is often more important that achieve obvious sober up effect.
Therefore, instant invention overcomes existing relieving alcoholic intoxication products material composition complexity, complex production process, the inapparent defect of sober up effect, it is provided that Soboring-up liver-protecting composition material composition simple, simple process is easy, and effect of relieving alcoholism and protecting the liver is obvious.
Detailed description of the invention
Further illustrating the present invention below by embodiment, the present invention is not limited only to described embodiment.
Embodiment one
The Soboring-up liver-protecting compositions of this example, is made up of major ingredient and adjuvant, and major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, product gross weight be 100kg, Radix Puerariae and Herba Lysimachiae Clethroids extract be 30kg;Adjuvant is the sucrose of 50kg, the Mel of 10kg, the milk powder of 6kg, the sodium citrate of 0.3kg, the citric acid of 0.3kg, the malic acid of 3.4kg.
The Soboring-up liver-protecting compositions of this example, its preparation method is as follows:
By Radix puerariae root and dry Herba Lysimachiae Clethroids, through cleaning, after cutting, by Radix puerariae root: dry Herba Lysimachiae Clethroids=1: the part by weight of 1 compounds, and must compound material.Extracting in water, during extraction, adds water by 8 times of multiple ingredients by weight, and normal pressure boils 1.5 hours, filters, and filtering residue extracts again, extracts 3 times altogether;Merging filtrate, stands, takes 60 DEG C~80 DEG C concentrating under reduced pressure of supernatant, and being concentrated into proportion is 1.15, is cooled to less than 40 DEG C, and concentrated solution adds 95% ethanol, is 60% to ethanol content, stirs, and stands 4~8 hours, filters;Filtrate heating recovery ethanol, concentrates, and measures solid content.Take the concentrated juice that solid content is 30kg, first sucrose and milk powder are mixed, add concentrated juice and Mel mixing, then citric acid, malic acid, sodium citrate it are sequentially added into, mix and blend 15~20 minutes, 12 mesh pelletize, 60 DEG C of drying under reduced pressure, 20 mesh granulate, the Soboring-up liver-protecting compositions obtained is graininess, weight packaging, quality inspection, packaging and warehousing, applies as electuary.
This example product sober up effect example:
Mr. Chen, 48 years old, drink Chinese liquor was less than 50 milliliters the most once in a while, just feels dizzy.Putting in cup dissolved with this example product 10 grams, work as beverage, while drink this example product limit drink Chinese liquor (53 ° of Maotai-flavor red pool wine), drink Chinese liquor has no dizziness and distending sensation of the head to 150 milliliters.
Embodiment two
The Soboring-up liver-protecting compositions of this example, is made up of major ingredient and adjuvant, and major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, product gross weight be 100kg, Radix Puerariae and Herba Lysimachiae Clethroids extract be 30kg;Adjuvant is the sucrose of 50kg, the starch of 10kg, the milk powder of 5kg, the Mel of 4.5kg, the Pulvis Talci of 0.5kg.
In preparation technology, take the concentrated juice that solid content is 30kg, first sucrose, milk powder and starch are mixed, adding concentrated juice and Mel mixing, 14 mesh are pelletized, and are dried, 20 mesh granulate, adding Pulvis Talci mixing, tabletting, the Soboring-up liver-protecting compositions obtained is lamellar, weight packaging, quality inspection, packaging and warehousing, apply as buccal sheet.
Remaining is with embodiment one.
This example product sober up effect example:
Miss Wu, 58 years old, can not drink at ordinary times.During experiment, she has first swallowed two panels this example product by warm water, and every 0.5 gram, after having drunk 100ml Chinese liquor (52 ° of Luzhou Old Cellars 1573), buccal two panels again, conscious do not have sense of discomfort.
Embodiment three
The Soboring-up liver-protecting compositions of this example, is made up of major ingredient and adjuvant, and major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, product gross weight be 100kg, Radix Puerariae and Herba Lysimachiae Clethroids extract be 20kg;Adjuvant is the sucrose of 60kg, the Mel of 9kg, the milk powder of 8kg, the citric acid of 0.4kg, the malic acid of 2.6kg.
Remaining is with embodiment one.
Embodiment four
The Soboring-up liver-protecting compositions of this example, is made up of major ingredient and adjuvant, and major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, product gross weight be 100kg, Radix Puerariae and Herba Lysimachiae Clethroids extract be 40kg;Adjuvant is the sucrose of 40kg, the Mel of 15kg, the milk powder of 4kg, the sodium citrate of 0.2kg, the malic acid of 0.8kg.
Remaining is with embodiment one.
Embodiment five
The Soboring-up liver-protecting compositions of this example, its preparation method is as follows:
By Radix puerariae root and dry Herba Lysimachiae Clethroids, through cleaning, after cutting, by Radix puerariae root: dry Herba Lysimachiae Clethroids=1: the part by weight of 0.5 compounds, and must compound material.Extracting in water, during extraction, adds water by 8 times of multiple ingredients by weight, and normal pressure boils 1 hour, filters, and filtering residue extracts again, extracts 2 times altogether;Merging filtrate, stands, takes 60 DEG C~80 DEG C concentrating under reduced pressure of supernatant, and being concentrated into proportion is 1.15, is cooled to less than 40 DEG C, and concentrated solution adds 95% ethanol, is 60% to ethanol content, stirs, and stands 4~8 hours, filters;Filtrate heating recovery ethanol, concentrates, and measures solid content.
Remaining is with embodiment one.
Embodiment six
The Soboring-up liver-protecting compositions of this example, its preparation method is as follows:
By Radix puerariae root and dry Herba Lysimachiae Clethroids, through cleaning, after cutting, by Radix puerariae root: dry Herba Lysimachiae Clethroids=1: the part by weight of 2 compounds, and must compound material.Extracting in water, during extraction, adds water by 10 times of multiple ingredients by weight, and normal pressure boils 1.5 hours, filters, and filtering residue extracts again, extracts 3 times altogether;Merging filtrate, stands, takes 60 DEG C~80 DEG C concentrating under reduced pressure of supernatant, and being concentrated into proportion is 1.15, is cooled to less than 40 DEG C, and concentrated solution adds 95% ethanol, is 60% to ethanol content, stirs, and stands 4~8 hours, filters;Filtrate heating recovery ethanol, concentrates, and measures solid content.
Remaining is with embodiment one.
Embodiment seven
The Soboring-up liver-protecting compositions of this example, is made up of major ingredient and adjuvant, and major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, product gross weight be 100kg, Radix Puerariae and Herba Lysimachiae Clethroids extract be 30kg;Adjuvant is the sucrose of 50kg, the starch of 5kg, the milk powder of 8kg, the Mel of 6.7kg, the Pulvis Talci of 0.3kg.Remaining is with embodiment two.
Claims (2)
1. a Soboring-up liver-protecting compositions, is made up of major ingredient and adjuvant, it is characterised in that major ingredient is the extract of Radix Puerariae and Herba Lysimachiae Clethroids, and by percentage to the quality, product gross weight is 100%, and Radix Puerariae and Herba Lysimachiae Clethroids extract are 20%~40%;Adjuvant is the sucrose of 40%~60%, the Mel of 4.5%~15%, the milk powder of 4%~8%, 0~the sodium citrate of 0.3%, 0~the citric acid of 0.3%, 0~the malic acid of 3.4%, 0~the starch of 10%, 0~the Pulvis Talci of 0.5%.
Soboring-up liver-protecting compositions the most according to claim 1, it is characterised in that the preparation method of described Soboring-up liver-protecting compositions is as follows:
By Radix puerariae root and dry Herba Lysimachiae Clethroids, through cleaning, after cutting, by Radix puerariae root: dry Herba Lysimachiae Clethroids=1: the part by weight of 0.5~2 compounds, and must compound material.Extracting in water, during extraction, adds water by 8~10 times of multiple ingredients by weight, and normal pressure boils 1~1.5 hour, filters, and filtering residue extracts again, extracts 2~3 times altogether;Merging filtrate, concentrates, and concentrated solution adds 95% ethanol, is 60% to ethanol content, stirs, and stands 4~8 hours, filters;Filtrate heating recovery ethanol, concentrates, and measures solid content, adds adjuvant, mixing granulation or film-making, weight packaging by formula, obtains finished product.
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CN201610347391.3A CN105816515A (en) | 2016-05-16 | 2016-05-16 | Composition for dispelling effect of alcohol and protecting liver |
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CN201610347391.3A CN105816515A (en) | 2016-05-16 | 2016-05-16 | Composition for dispelling effect of alcohol and protecting liver |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107951030A (en) * | 2017-12-04 | 2018-04-24 | 浙江农林大学 | A kind of compound granule with Antialcoholic liver-protecting and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN87105710A (en) * | 1987-08-24 | 1988-05-18 | 河南省医学科学研究所 | The production technology of kudzu root beverage |
CN1224618A (en) * | 1998-12-22 | 1999-08-04 | 陈臻 | Preparation of liver protecting and drunkenness dispelling liquid medicine |
-
2016
- 2016-05-16 CN CN201610347391.3A patent/CN105816515A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN87105710A (en) * | 1987-08-24 | 1988-05-18 | 河南省医学科学研究所 | The production technology of kudzu root beverage |
CN1224618A (en) * | 1998-12-22 | 1999-08-04 | 陈臻 | Preparation of liver protecting and drunkenness dispelling liquid medicine |
Non-Patent Citations (1)
Title |
---|
黄亚东,等。: ""葛根醒酒保肝饮料的开发研究"", 《酿酒科技》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107951030A (en) * | 2017-12-04 | 2018-04-24 | 浙江农林大学 | A kind of compound granule with Antialcoholic liver-protecting and preparation method thereof |
CN107951030B (en) * | 2017-12-04 | 2021-01-01 | 浙江农林大学 | Compound granule with functions of dispelling effects of alcohol and protecting liver and preparation method thereof |
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Application publication date: 20160803 |