CN105794785A - Fungicidal composition - Google Patents
Fungicidal composition Download PDFInfo
- Publication number
- CN105794785A CN105794785A CN201610196282.6A CN201610196282A CN105794785A CN 105794785 A CN105794785 A CN 105794785A CN 201610196282 A CN201610196282 A CN 201610196282A CN 105794785 A CN105794785 A CN 105794785A
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- CN
- China
- Prior art keywords
- bactericidal composition
- ammonium salt
- quaternary ammonium
- weight ratio
- fluoxastrobin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a fungicidal composition.The fungicidal composition is characterized by being prepared by compounding biquaternary ammonium salt with azoxystrobin, wherein the weight ratio of the biquaternary ammonium salt to the azoxystrobin is 15:1-1:15.According to the fungicidal composition, the two effective ingredients are combined to be used, the fungicidal spectrum is widened, multiple crop diseases caused by fusarium oxysporum, small spore withering bacteria, powdery mildew, penicillium, botrytis cinerea, verturia noshicola, rust fungi, physalospora piricola and the like can be excellently prevented and treated, the fungicidal effect is improved compared with the effect generated when the biquaternary ammonium salt or the azoxystrobin is used as a fungicide alone, and the cost is reduced.
Description
Technical field
The present invention relates to technical field of pesticide, particularly to a kind of bactericidal composition.
Background technology
Since quaternary ammonium salt antibacterial emerges, with superiority such as its low toxicity, efficient, broad-spectrum antiseptics
Can, have been widely used for the fields such as medical science, food, cosmetics, weaving and Treatment of Industrial Water,
The applied research in the field such as leather, timber industry also has been achieved with being in progress.Quaternary ammonium salt is a class
Cationic surfactant, has hydrophilic, adsorptivity and the surface activity of excellence.Its sterilization machine
Reason is usually so thought: the cell wall of bacterium surface is electronegative, carries in quaternary ammonium compound
The organic cation of positive charge can be adsorbed by electronegative selective bacterium, is made by infiltration and diffusion
With, through surface entrance cell membrane, thus the semi-permeable effect of block cell film, and be further penetrated through
Cell interior, makes cellular enzymes be passivated, it is impossible to produce protease, so that protein denaturation reaches to kill
The effect of dead bacterial cell.
Although quaternary ammonium salt bactericide has good bactericidal property, but if long-term solely use should
Class medicament, easily develops immunity to drugs, and need to be continuously increased dosage.While increasing Financial cost,
Due to the increase of dosage, its toxicity also can not be ignored, thus limits the use of this series products.
In order to improve bactericidal property, reduce toxicity, reduce Drug resistance as far as possible, it is thus proposed that double quaternary ammoniums
Salt compound, and carried out substantial amounts of research work.This compounds uses a connection base or claims chain
The quaternary ammonium salt molecule that two are traditional is linked up by bridge so that each compound molecule contain two hydrophilic
Base and two hydrophobic groups, and the N of two positive charges+Ion.Show as bigger surface activity, especially
It is owing to molecule having two positively charged N+, it is more beneficial for the biocide molecules suction at bacterium surface
Attached, thus change the permeability of cell wall, make thalline rupture；After antibacterial is adsorbed onto phage surface,
Be conducive to hydrophobic group and hydrophilic group to penetrate into class lipid layer and the albumin layer of somatic cells respectively, cause enzyme to lose
Activity.
Kresoxim-methyl be a kind of efficiently, wide spectrum, new type bactericide, have Uptake and translocation, prevent, protect,
The multiple actions such as treatment, can suppress almost all of mycota (Ascomycotina, Basidiomycotina,
Mastigomycotina and Deuteromycotina) sprouting of pathogenic bacteria spore and generation, it is possible to control mycelial life
Long.And may also suppress Spores to invade, there is good protection activity, the most effectively control vegetables
The various fungal diseases of the plants such as dish, fruit tree, flowers, such as powdery mildew, downy mildew, scab, charcoal
Cellulitis disease, rust, epidemic disease, glume blight, net blotch, rice blast etc..Especially to powdery mildew of strawberry, sweet
Melon powdery mildew, powdery mildew of cucumber, pear scab specially good effect.
Summary of the invention
For solving the problem of above-mentioned existence, it is an object of the invention to provide a kind of bactericidal composition.Institute
Stating bactericidal composition, two kinds of combination of active principles use, and expand fungicidal spectrum, preventing and treating that can be fabulous
Fusarium spp., the little spore bacterium that withers, powdery mildew, penicillium, botrytis cinerea, black star bacterium, aecidium, ring spot
The various crop disease that bacterium etc. cause, is relatively used alone bi-quaternary ammonium salt or Fluoxastrobin and improves as antibacterial
Bactericidal effect, and reduce cost.
For reaching above-mentioned purpose, the technical scheme is that
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 15:1-1:15.
Separately having, the weight ratio of described bi-quaternary ammonium salt and Fluoxastrobin is 8:1-1:8.
And, the weight ratio of described bi-quaternary ammonium salt and Fluoxastrobin is 1:3.
Meanwhile, described bactericidal composition is prepared as wettable powder or suspending agent or water dispersible granules or breast
Any one in oil.
Again, in described wettable powder, the mass fraction of bactericidal composition is 15-25%.
And have, in described suspending agent or water dispersible granules or cream, the mass fraction of bactericidal composition is
10-18%.
Further, described bactericidal composition is applied to agricultural vegetable, the preventing and treating of melon and fruit disease.
The beneficial effects of the present invention is:
(1) a kind of bactericidal composition that the present invention provides, two kinds of combination of active principles use, and expand
Fungicidal spectrum, preventing and treating Fusarium spp. that can be fabulous, the little spore bacterium that withers, powdery mildew, penicillium, botrytis cinerea,
The various crop disease that black star bacterium, aecidium, Target spot pathogen etc. cause.
(2) a kind of bactericidal composition that the present invention provides, potentiation is notable, is relatively used alone bi-quaternary ammonium salt
Or Fluoxastrobin improves bactericidal effect as antibacterial, and reduce cost.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with enforcement
Example further describes.
Embodiment 1
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:3, and described bactericidal composition is prepared as wettable powder,
In described wettable powder, the mass fraction of bactericidal composition is 18%.
Embodiment 2
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 8:1, and described bactericidal composition is prepared as wettable powder,
In described wettable powder, the mass fraction of bactericidal composition is 15%.
Embodiment 3
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 18:1, and described bactericidal composition is prepared as water dispersible granules,
In described water dispersible granules, the mass fraction of bactericidal composition is 10%.
Embodiment 4
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:1, and described bactericidal composition is prepared as cream, described breast
In oil, the mass fraction of bactericidal composition is 18%.
Embodiment 5
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:3.5, and described bactericidal composition is prepared as suspending agent, institute
Stating the mass fraction of bactericidal composition in suspending agent is 10%.
Embodiment 6
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:5, and described bactericidal composition is prepared as suspending agent, described
In suspending agent, the mass fraction of bactericidal composition is 15%.
Embodiment 7
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:10, and described bactericidal composition is prepared as wettable powder,
In described wettable powder, the mass fraction of bactericidal composition is 25%.
Embodiment 8
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:12, and described bactericidal composition is prepared as suspending agent, institute
Stating the mass fraction of bactericidal composition in suspending agent is 15%.
Embodiment 9
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:18, and described bactericidal composition is prepared as water dispersible granules,
In described water dispersible granules, the mass fraction of bactericidal composition is 10%.
Embodiment 10
A kind of bactericidal composition, described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, institute
The weight ratio stating bi-quaternary ammonium salt and Fluoxastrobin is 1:6, and described bactericidal composition is prepared as cream, described breast
In oil, the mass fraction of bactericidal composition is 12%.
In order to the effect of bactericidal composition in embodiment 1-10 being tested, by embodiment 1-10 not
Bi-quaternary ammonium salt and Fluoxastrobin with proportioning have carried out Toxicity Determination.Test uses leaf butterfly moisturizing method to enter
Row toxicity test.The infected leaves of collection is prepared as the leaf dish of a diameter of 1.5cm, mixes at random,
Being respectively placed in the series concentration medicinal liquid configured immersion 1h, 50 leaf dishes of each concentration, test is not with
The process of adding medicine is blank.After immersion terminates, leaf faces up, and to be placed in identical medicinal liquid dense
In the absorbent paper that degree is moistening, the medicinal liquid on blade is blotted, the spore suspension 10L prepared is connect
Kind in leaf dish central authorities, room temperature is placed after 5min, is placed in 20 DEG C, cultivates under conditions of 12 alternation of light and darkness,
Measure the onset area on leaf dish after 10d, calculate EC50, then calculate co-toxicity coefficient by the abundant method of Sun Yun
(CTC)。
Co-toxicity coefficient (CTC) >=120 shows as potentiation；Co-toxicity coefficient (CTC) 80 table
It it is now antagonism；< 120 show as summation action to 80 < co-toxicity coefficient (CTC).
Actual measurement toxicity index (ATI)=(standard agent EC50/ reagent agent EC50)×100
Theoretical toxicity index (TTI)=(percentage composition of A in the toxicity index × mixture of A)+(B
Toxicity index × mixture in the percentage composition of B)
Co-toxicity coefficient (CTC)=[mixture actual measurement virulence coefficient (ATI)/mixture theory virulence coefficient (TTI)]
× 100 co-toxicity coefficients.
Table 1 is the embodiment 1-10 recipe determination result to powdery mildew of cucumber pathogenic bacteria.
| EC50(μg/mL) | ATI | TTI | CTC | |
| Embodiment 1 | 39.2 | 190.7 | 121.1 | 147.7 |
| Embodiment 2 | 48.1 | 161.1 | 119.4 | 134.9 |
| Embodiment 3 | 41.5 | 178.5 | 131.6 | 135.6 |
| Embodiment 4 | 50.3 | 154.8 | 120.5 | 128.5 |
| Embodiment 5 | 23.5 | 223.3 | 124.9 | 178.8 |
| Embodiment 6 | 17.9 | 242.6 | 175.7 | 138.1 |
| Embodiment 7 | 33.7 | 202.5 | 156.5 | 129.4 |
| Embodiment 8 | 10.6 | 299.8 | 180.6 | 166.0 |
| Embodiment 9 | 9.5 | 331.5 | 209.5 | 158.2 |
| Embodiment 10 | 11.2 | 270.4 | 186.4 | 145.1 |
As seen from the above table, bi-quaternary ammonium salt and azoxystrobin compound, the CTC value of embodiment 1-10 all exceedes
120, good potentiation has been described.Two kinds of combination of active principles use, and have good sterilization effect
Really, can be applicable to the preventing and treating of the disease of agricultural vegetable, melon and fruit.
It should be noted that above example is only in order to illustrate technical scheme and unrestricted.
Although being described in detail the present invention with reference to preferred embodiment, those of ordinary skill in the art should
Work as understanding, the technical scheme of invention can be modified or equivalent, without deviating from the present invention
The scope of technical scheme, it all should be contained in scope of the presently claimed invention.
Claims (7)
1. a bactericidal composition, it is characterised in that described bactericidal composition is formed by bi-quaternary ammonium salt and azoxystrobin compound, the weight ratio of described bi-quaternary ammonium salt and Fluoxastrobin is 15:1-1:15.
A kind of bactericidal composition the most according to claim 1, it is characterised in that the weight ratio of described bi-quaternary ammonium salt and Fluoxastrobin is 8:1-1:8.
A kind of bactericidal composition the most according to claim 1, it is characterised in that the weight ratio of described bi-quaternary ammonium salt and Fluoxastrobin is 1:3.
A kind of bactericidal composition the most according to claim 1, it is characterised in that described bactericidal composition is prepared as any one in wettable powder or suspending agent or water dispersible granules or cream.
A kind of bactericidal composition the most according to claim 1, it is characterised in that in described wettable powder, the mass fraction of bactericidal composition is 15-25%.
A kind of bactericidal composition the most according to claim 1, it is characterised in that in described suspending agent or water dispersible granules or cream, the mass fraction of bactericidal composition is 10-18%.
A kind of bactericidal composition the most according to claim 1, it is characterised in that described bactericidal composition is applied to agricultural vegetable, the preventing and treating of melon and fruit disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610196282.6A CN105794785A (en) | 2016-03-31 | 2016-03-31 | Fungicidal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610196282.6A CN105794785A (en) | 2016-03-31 | 2016-03-31 | Fungicidal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105794785A true CN105794785A (en) | 2016-07-27 |
Family
ID=56459338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610196282.6A Pending CN105794785A (en) | 2016-03-31 | 2016-03-31 | Fungicidal composition |
Country Status (1)
| Country | Link |
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| CN (1) | CN105794785A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050227956A1 (en) * | 2004-04-13 | 2005-10-13 | Ying Wang | Control of mold growth on wood |
| CN1913777A (en) * | 2004-02-04 | 2007-02-14 | 詹森药业有限公司 | Synergistic antifungal DDAC compositions |
| CN101810180A (en) * | 2009-11-25 | 2010-08-25 | 陕西永泰生物工程有限责任公司 | Crop bactericide composition and preparation method thereof |
-
2016
- 2016-03-31 CN CN201610196282.6A patent/CN105794785A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1913777A (en) * | 2004-02-04 | 2007-02-14 | 詹森药业有限公司 | Synergistic antifungal DDAC compositions |
| US20050227956A1 (en) * | 2004-04-13 | 2005-10-13 | Ying Wang | Control of mold growth on wood |
| CN101810180A (en) * | 2009-11-25 | 2010-08-25 | 陕西永泰生物工程有限责任公司 | Crop bactericide composition and preparation method thereof |
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Application publication date: 20160727 |