CN105792832B - 用于治疗乙肝病毒的有机化合物 - Google Patents

用于治疗乙肝病毒的有机化合物 Download PDF

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CN105792832B
CN105792832B CN201480054710.0A CN201480054710A CN105792832B CN 105792832 B CN105792832 B CN 105792832B CN 201480054710 A CN201480054710 A CN 201480054710A CN 105792832 B CN105792832 B CN 105792832B
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strand
phosphate
end cap
mer
rnai agent
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CN105792832A (zh
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J·L·巴伊扎
M·布洛默
C·费尔南德斯
E·格诺
A·戈赛特
P·格里尼奇
D·许斯肯
J·亨齐克
F·J-C·纳特
A·帕特奈克
A·帕特森
J-M·R·隆多
J·魏勒
M·朱
M·霍尔多夫
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Novartis AG
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CN201480054710.0A 2013-10-04 2014-09-30 用于治疗乙肝病毒的有机化合物 Active CN105792832B (zh)

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US201361886760P 2013-10-04 2013-10-04
US61/886,760 2013-10-04
PCT/US2014/058314 WO2015050871A2 (en) 2013-10-04 2014-09-30 Organic compounds to treat hepatitis b virus

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CN105792832B true CN105792832B (zh) 2021-03-23

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US (1) US10519446B2 (https=)
EP (1) EP3052107B1 (https=)
JP (1) JP6546161B2 (https=)
CN (1) CN105792832B (https=)
HK (1) HK1221912A1 (https=)
WO (1) WO2015050871A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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EA024762B9 (ru) 2011-06-30 2017-04-28 Эрроухэд Рисерч Корпорейшн Композиции и способы ингибирования экспрессии генов вируса гепатита в
HK1221912A1 (zh) 2013-10-04 2017-06-16 Novartis Ag 用於治疗乙肝病毒的有机化合物
EP3052464B1 (en) * 2013-10-04 2020-04-15 Novartis AG 3'end caps for rna-interferring agents for use in rna interference
WO2015051366A2 (en) 2013-10-04 2015-04-09 Novartis Ag Novel formats for organic compounds for use in rna interference
US20170137821A1 (en) 2015-07-17 2017-05-18 Arcturus Therapeutics, Inc. Molecules and agents for treating hepatitis b virus
CA2996722A1 (en) * 2015-07-17 2017-01-26 Arcturus Therapeutics, Inc. Compositions and agents against hepatitis b virus and uses thereof
AU2016306275A1 (en) 2015-08-07 2018-02-08 Arrowhead Pharmaceuticals, Inc. RNAi therapy for Hepatitis B virus infection
JOP20190015A1 (ar) * 2016-08-04 2019-02-04 Arrowhead Pharmaceuticals Inc عوامل (ار ان ايه آي) لعدوى فيروس الالتهاب الكبدي الوبائي ب
CN110446259B (zh) * 2018-05-04 2022-04-15 大唐移动通信设备有限公司 一种寻呼机会的位置确定方法及通信设备
CN116157522A (zh) * 2020-08-21 2023-05-23 豪夫迈·罗氏有限公司 A1cf抑制剂用于治疗乙型肝炎病毒感染的用途

Citations (1)

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CN103140582A (zh) * 2010-08-24 2013-06-05 默沙东公司 含有内部非核酸间隔子的单链RNAi试剂

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