CN105767419A - Production method of caries-prevention candies - Google Patents

Production method of caries-prevention candies Download PDF

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Publication number
CN105767419A
CN105767419A CN201610208356.3A CN201610208356A CN105767419A CN 105767419 A CN105767419 A CN 105767419A CN 201610208356 A CN201610208356 A CN 201610208356A CN 105767419 A CN105767419 A CN 105767419A
Authority
CN
China
Prior art keywords
antibacterial polypeptide
confection
caries
sugar
candies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610208356.3A
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Chinese (zh)
Inventor
凌建群
俞苏鸣
杨磊
俞祖勋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genloci Biotechnologies Inc.
Original Assignee
俞祖勋
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 俞祖勋 filed Critical 俞祖勋
Priority to CN201610208356.3A priority Critical patent/CN105767419A/en
Publication of CN105767419A publication Critical patent/CN105767419A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/44Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/10COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing amino-acids, proteins, e.g. gelatine, peptides, polypeptides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention relates to a production method of caries-prevention candies. The production method comprises the following steps: (1) preparing antibacterial polypeptide raw materials and candy raw materials; and (2) adding the antibacterial polypeptide raw materials into a candy production process, namely adding antibacterial polypeptide components into the candies. The preparation of antibacterial polypeptide comprises the steps of dissolving antibacterial polypeptide concentrated crystal powder with the content of 80%-100% with pure water, and diluting to obtain a solution with the concentration of 0.001%-5% for later use; a production process of the candies sequentially comprises the steps of melting sugar, filtering, boiling, cooling, adding auxiliary materials, blending, molding, screening, internally packaging, checking a finished product, externally packaging, and storing; the antibacterial polypeptide diluted solution is added in the step of melting sugar, so that the antibacterial polypeptide components are uniformly distributed into the raw materials of the candies. The production method of the caries-prevention candies has the advantages that technology is simple, the effect of preventing caries is obvious, and a condition that caries is easy to cause when candies are eaten is changed.

Description

A kind of manufacture method of anti-caries confection
Technical field
The present invention relates to the manufacture method of a kind of anti-caries confection, belong to confection processing and manufacturing field.
Background technology
Antibacterial polypeptide is a kind of micromolecule polypeptide with antibacterial, antiviral and anti-tumor activity being widely present in nature biotechnology.Research shows, the has a broad antifungal spectrum of antibacterial polypeptide, killing microorganisms effect strong, in terms of suppression bacterial translocation, preventing and treating infection, effect is special, and it has the various active such as antibacterium, mycete, virus, protozoon, cancerous cell, spirillum.In addition to antibacterial activity, a lot of antibacterial polypeptides also have antitumor, promote other biological activity such as wound healing and protection sperm.
Dental caries is also called decayed tooth, is the disease of antibacterial initiation.Alveolar bone and inflammation of jaws can be caused time serious with secondary pulpitis and periapical periodontitis.Form cavity as treatment can allow pathological changes continue development not in time, finally make corona destroy disappearance completely, need to pull out tooth.The feature of dental caries is that sickness rate is high, and distribution is wide.Being the main commonly encountered diseases in oral cavity, be also one of most common disease of the mankind, it is listed as the big keypoint control disease of the mankind three with tumor and cardiovascular disease by World Health Organization (WHO).
Antibacterial is the basic reason that dental caries occurs.It is generally acknowledged that the antibacterial of cariogenic tooth has two big classes, a class is that the effect of the such as antibacterial such as Streptococcus mutans, actinomyces and lactobacillus makes carbohydrate breakdown produce acid, causes tooth by progressively corrosion failure;The organic matter of the another kind of action breaks down tooth being gram-positive cocci, can make tooth form cavity through invading corruption for a long time.Owing to the corrosion of tooth is injured by antibacterial incessantly, result in dental caries.The growth of porphyromonas gingivalis is also closely related with the generation of periodontitis.
Dental caries is the biggest to the hazardness of child.Caries in primary teeth develops into periapical disease can make its hetero-organization generation focal infection of body as focus tooth, causes masticatory function to reduce, affects the nutrition intake of child, impact growth promoter.The oral cavity mucous membrane tissue of easy damaged local;Make oral hygiene deteriorate, affect permanent teeth generation dental caries and suffer from;Permanent teeth dental gram is inherited in the impact of deciduous teeth periapical periodontitis, causes its enamel development and normal eruption obstacle;Affect attractive in appearance and orthoepy etc..
Domestic also have some pre-anticariogenic patents:
Patent application such as Patent No. CN201410363586.8: " dental caries chewing gum ", uses Chinese medicine composition Fructus Momordicae, Radix Glycyrrhizae, Galla Chinensis, the Radix Angelicae Dahuricae, Herba Menthae, Flos Caryophylli, Folium Nelumbinis, Cortex Magnoliae Officinalis etc..Literary composition claims " binding ability of the active component in the dental caries chewing gum of the present invention and Streptococcus mutans is relatively strong, in Streptococcus mutans cyton can be directly entered thus play the effect killing antibacterial." but to can result in the harmful bacteria that dental caries occurs in oral cavity a lot, Streptococcus mutans is the most important one.
Patent application such as Patent No. CN201310255622.4: " a kind of pre-anticariogenic confection " employing Chinese herbal medicine: the pre-anti-caries of combination of Flos Chrysanthemi, Radix Glycyrrhizae, Herba Menthae and aminoacid, vitamin C, Exocarpium Citri Rubrum powder etc..Because the well-known antibacterial ability of these Chinese herbal medicine is limited, especially broad spectrum activity antibacterial ability is weak, and estimation effect can be problematic.
Patent application such as Patent No. CN200980113038.7: the Radix Glycyrrhizae that " the Radix Glycyrrhizae lollipop that suppression dental caries is formed " uses some extract of Radix Glycyrrhizae that dental caries particularly can be suppressed to be formed makes lollipop.But some extract of Radix Glycyrrhizae is obvious to the inhibitory action of some antibacterial, and Radix Glycyrrhizae is found to have broad-spectrum antiseptic ability currently without by pharmacy circle.
Based on factors above, the application uses antibacterial polypeptide to manufacture pre-anticariogenic confection.
Summary of the invention
Present invention solves the technical problem that the manufacture method being to provide a kind of anti-caries confection, making pre-anticariogenic technology tend to perfect, than using plant and the exploitation of Chinese herbal medicine extracting type, chemosynthesis type antibacterial additives, pre-anticariogenic confectionary products technology is simple, effect is obvious.And can change and eat sugar and easily cause caries condition.The new consumption view of confection consumer is led: eat sugared pre-anti-caries with brand-new confectionary products.
Confection itself is not result in decayed tooth, real arch-criminal be chewed confection after remain in the noxious bacteria of dental surface, these noxious bacteria are in the environment of oral cavity warm and moist, in the eutrophic environment of food residual, make a kind of acidic materials eroding dental enamel of carbohydrate breakdown release, cause dental caries.Organic matter plus the action breaks down dental surface of gram-positive cocci.These harm make dental caries occur, and cavity produces, injury of teeth.
If adding in confection and can killing antibacterial, the antibacterial polypeptide that will not work the mischief human body again, substantially being killed by the antibacterial entering oral cavity, will not work the mischief health again during eating sugar, people eat sugar just need not worry generation dental caries.Thus change people and eat sugar and can cause the idea of dental caries.
The invention aims to help to like enjoying confection, the crowd of chocolate avoids and the hardship of pre-anti-caries.
Indication confection of the present invention is: lollipop, hard caked sugar, soft caked sugar, gel sugar, chewing gum, chocolate caked sugar and other all confectionary products.
The present invention solves above-mentioned technical problem and be the technical scheme is that the manufacture method of a kind of anti-caries confection, and its technological process of production is as follows:
(1), the preparation of antibacterial polypeptide raw material and the preparation of candy raw material,
(2) in confection production process, add antibacterial polypeptide raw material, make antibacterial polypeptide composition add in confection.
The preparation of antibacterial polypeptide of the present invention includes that, by content antibacterial polypeptide condensing crystallizing powder dissolved in purified water between 80-100%, being diluted to concentration is 0.001-5% solution for standby;Described confection production process is the sugar of carrying out successively, filters, boils, cools down, adds adjuvant, mediation, molding, screening, inner packing, product inspection, outer package, warehouse-in step, and antibacterial polypeptide dilute solution is added in changing sugar step, make antibacterial polypeptide composition be evenly distributed in inside the raw material of confection.
The preparation of antibacterial polypeptide of the present invention can also use and make one layer of sugar-coat containing antibacterial polypeptide, described confection production process be successively carrying out sugar, filter, boil, cool down, add adjuvant, mediation, molding, the sugar-coat containing antibacterial polypeptide is wrapped up outside confection after shaping, screening, inner packing, product inspection, outer package, warehouse-in step.
The broad spectrum antibacterial performance that the present invention uses antibacterial polypeptide excellent manufactures the application in field at confection, pre-anticariogenic technology is made to tend to perfect, compared with using plant and Chinese herbal medicine extracting type, the chemosynthesis type antibacterial additives pre-anticariogenic confection of exploitation, technology is simple, effect is obvious, and can change and eat sugar and easily cause caries condition.The new consumption view of confection consumer is led: eat sugared pre-anti-caries with brand-new confectionary products.
Accompanying drawing explanation
Fig. 1 is a kind of process chart of the embodiment of the present invention.
Detailed description of the invention
The manufacture method of embodiment of the present invention anti-caries confection, its technological process of production is as follows:
(1), the preparation of antibacterial polypeptide raw material and the preparation of candy raw material,
(2) in confection production process, add antibacterial polypeptide raw material, make antibacterial polypeptide composition add in confection.
The preparation of antibacterial polypeptide of the present invention includes content antibacterial polypeptide condensing crystallizing powder dissolved in purified water between 80-100%, is diluted to the mass percent that concentration is 0.001%-5%(i.e. antibacterial polypeptide and antibacterial polypeptide solution, lower same) solution for standby;Described confection production process is the sugar of carrying out successively, filters, boils, cools down, adds adjuvant, mediation, molding, screening, inner packing, product inspection, outer package, warehouse-in step, and antibacterial polypeptide dilute solution is added in changing sugar step, make antibacterial polypeptide composition be evenly distributed in inside the raw material of confection.
After the present embodiment can also use the method according to traditional mode of production confection confection manufacture to be completed, the surface of confection is covered one layer of sugar-coat containing antibacterial polypeptide, be wrapped inside dress and other later flow processs the most again.The another kind of method for preparing of antibacterial polypeptide the most of the present invention is to make one layer of sugar-coat containing antibacterial polypeptide, described confection production process be successively carrying out sugar, filter, boil, cool down, add adjuvant, mediation, molding, the sugar-coat containing antibacterial polypeptide is wrapped up outside confection after shaping, screening, inner packing, product inspection, outer package, warehouse-in step.
The present invention is except changing sugar step and the sugar-coat containing antibacterial polypeptide wraps up the candy production method of other technological process of production and routine beyond the outer step of confection being after shaping as good as.
Antibacterial polypeptide solution of the present invention is to common oral anaerobe: the resistant determination result of porphyromonas gingivalis and Streptococcus mutans is as follows:
Note: 1. porphyromonas gingivalis is standard strain ATCC33277;
2. Streptococcus mutans is standard strain ATCC25175;
3. test is performed according to " disinfection technology standard " 2002 editions-2.1.11.3.1 by microbiological analysis inspection center of Guangdong Province.
Embodiment 1:
Pre-anticariogenic lollipop manufacture method, its technological process of production is as follows:
1, the preparation of antibacterial polypeptide solution and the preparation of candy raw material, the preparation of described antibacterial polypeptide includes content antibacterial polypeptide condensing crystallizing powder dissolved in purified water between 80-100%, being diluted to concentration is 50PPM~500PPM, and the change sugar link at confectioner process flow uses.
2, according to normal confection producting rule, carrying out is sugared successively, filter, boil, cool down, add adjuvant, mediation, molding, screening, inner packing, product inspection, outer package, warehouse-in step, and produce the addition in changing sugar step of dispensing water with above-mentioned standby antibacterial polypeptide dilute solution replacement water as confection, make antibacterial polypeptide composition be evenly distributed in inside the raw material of confection.
The present invention can also use after having been manufactured according to the method for traditional mode of production lollipop, covers one layer of sugar-coat containing antibacterial polypeptide on the surface of lollipop, is wrapped inside dress and other later flow processs the most again.
Embodiment 2:
The specific implementation method of pre-anticariogenic hard sugar manufacture method is substantially with embodiment 1, and the concentration differing only in antibacterial polypeptide is 100PPM~300PPM.
Embodiment 3:
Pre-anticariogenic gel sugar manufacture method specific implementation method is substantially with embodiment 1, and the concentration differing only in antibacterial polypeptide is 100PPM~600PPM.
Embodiment 4:
Being prepared as of the present embodiment antibacterial polypeptide makes one layer of sugar-coat containing antibacterial polypeptide, and use content antibacterial polypeptide condensing crystallizing powder dissolved in purified water between 80-100% to be diluted to when making the sugar-coat of antibacterial polypeptide solution that concentration is 100PPM~2000PPM is as industrial water;Described confection production process be successively carrying out sugar, filter, boil, cool down, add adjuvant, mediation, molding, the sugar-coat containing antibacterial polypeptide is wrapped up that confection after shaping is outer, screening, inner packing, product inspection, outer package, warehouse-in step.
More than it is being embodied as under technical solution of the present invention framework, every embodiment of the present invention technical scheme and the simple deformation of technical characteristic or combination, is all deemed to fall protection scope of the present invention.

Claims (3)

1. the manufacture method of an anti-caries confection, it is characterised in that comprise the following steps:
(1) preparation of antibacterial polypeptide raw material and the preparation of candy raw material;
(2) in confection production process, antibacterial polypeptide raw material is added.
The manufacture method of anti-caries confection the most according to claim 1, it is characterised in that:
The preparation of described antibacterial polypeptide includes that, by content antibacterial polypeptide condensing crystallizing powder dissolved in purified water between 80-100%, being diluted to concentration is 0.001-5% solution for standby;Described confection production process is the sugar of carrying out successively, filters, boils, cools down, adds adjuvant, mediation, molding, screening, inner packing, product inspection, outer package, warehouse-in step, and antibacterial polypeptide dilute solution is added in changing sugar step, make antibacterial polypeptide composition be evenly distributed in inside the raw material of confection.
The manufacture method of anti-caries confection the most according to claim 1, it is characterised in that:
Being prepared as of described antibacterial polypeptide makes one layer of sugar-coat containing antibacterial polypeptide, described confection production process be successively carrying out sugar, filter, boil, cool down, add adjuvant, mediation, molding, the sugar-coat containing antibacterial polypeptide is wrapped up confection after shaping outward, screening, inner packing, product inspection, outer package, warehouse-in step.
CN201610208356.3A 2016-04-06 2016-04-06 Production method of caries-prevention candies Pending CN105767419A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106666027A (en) * 2016-12-31 2017-05-17 俞苏鸣 Manufacture method for caries prevention candy and lollipop thereof
CN107094967A (en) * 2017-04-18 2017-08-29 荣海生物科技有限公司 A kind of Soybean Peptide candy and preparation method thereof
CN107233228A (en) * 2017-07-20 2017-10-10 杭州坦珮信息技术有限公司 A kind of manufacture method of anti-halitosis and carious tooth toothpaste

Citations (3)

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Publication number Priority date Publication date Assignee Title
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CN1922203A (en) * 2004-01-19 2007-02-28 卢卡斯·海布雷赫特 Anticariogenic proteins and peptides and saccharides
CN101511382A (en) * 2006-09-06 2009-08-19 加利福尼亚大学董事会 Selectively targeted antimicrobial peptides and the use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1639318A (en) * 2002-02-22 2005-07-13 布利斯技术有限公司 Antimicrobial composition
CN1922203A (en) * 2004-01-19 2007-02-28 卢卡斯·海布雷赫特 Anticariogenic proteins and peptides and saccharides
CN101511382A (en) * 2006-09-06 2009-08-19 加利福尼亚大学董事会 Selectively targeted antimicrobial peptides and the use thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106666027A (en) * 2016-12-31 2017-05-17 俞苏鸣 Manufacture method for caries prevention candy and lollipop thereof
CN107094967A (en) * 2017-04-18 2017-08-29 荣海生物科技有限公司 A kind of Soybean Peptide candy and preparation method thereof
CN107233228A (en) * 2017-07-20 2017-10-10 杭州坦珮信息技术有限公司 A kind of manufacture method of anti-halitosis and carious tooth toothpaste

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Effective date of registration: 20170125

Address after: 210036 Gulou District, Nanjing, Hanzhoung No. 301 Main Street, building 13, block A, 01,

Applicant after: Genloci Biotechnologies Inc.

Address before: 310053 Binjiang District, Hangzhou, South Ring Road, No. 23, building 3758, building

Applicant before: Yu Zuxun

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20160720