CN105749002A - Medicine for treating viral hepatitis A and preparation method - Google Patents

Medicine for treating viral hepatitis A and preparation method Download PDF

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CN105749002A
CN105749002A CN201610207112.3A CN201610207112A CN105749002A CN 105749002 A CN105749002 A CN 105749002A CN 201610207112 A CN201610207112 A CN 201610207112A CN 105749002 A CN105749002 A CN 105749002A
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parts
fructus
medicine
rhizoma
hepatitis
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李爱梅
范常云
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Abstract

The invention discloses a medicine for treating viral hepatitis A and a preparation method, belonging to the field of traditional Chinese medicines. The active ingredients of the medicine consist of the following raw materials: herpetospermum pedunculosum, serissa serissoides, mesora chinensis, gentianopsis barbata, platycladi seed, willow branch, horseweed herb, trichosanthes kirilowii, herba cepbalanoplosis segeti, yine abrus, lotus root, Indian rorippa herb, schisandra chinensis, fructus forsythiae, fig and reed rhizome. With appropriate compatibility of the medicinal materials, the medicine disclosed by the invention conforms to the theories of the traditional Chinese medicine and modern medicine, has the functions of nourishing blood and soothing the liver, resolving stasis and removing toxin and activating blood and clearing heat, realizes a remarkable curative effect on the viral hepatitis A, and has the advantages of short treatment course, high effect taking speed, no relapse after healing and safety without toxic or side effect; and moreover, the medicine can improve the immunity of the organism, promises a remarkable effect, is practical and deserves clinical wide promotion and application.

Description

A kind of medicine treating hepatitis A and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine treating hepatitis A and preparation method.
Background technology
Hepatitis A, it is called for short hepatitis A, hepatitis A, hepatitis A virus causes, based on the infectious disease of inflammation pathological changes, propagate mainly through fecal oral route, clinically with tired, loss of appetite, hepatomegaly, abnormal liver function is main manifestations, there is jaundice in some cases, and main manifestations is acute hepatitis, and symptomless infection person is common.Any age all can suffer from primary disease, but is mainly Children and teenager, and the general relatively child of clinical symptoms of adult's hepatitis A attaches most importance to, and winter-spring season is often the peak period of hepatitis A morbidity.
Hepatitis A virus HAV is a member of Picornaviridae, for heparnavirus.HAV be passed transorally into internal after, enter blood flow through intestinal, cause viremia, about cross and arrive liver after one week, enter intestinal by bile subsequently and occur in feces, feces toxin expelling can maintain 1-2 week.The major organs that virus is invaded is liver, pharyngeal and tonsil is probably outside HAV liver the position of breeding, the mechanism that HAV causes hepatocyte injury is not yet clear and definite, it is considered that HAV does not directly cause liver cell lesion, and the immunopathogenesis reaction that liver injury is HAV infected liver cell is caused.Hepatitis A patient and symptomless infection person are the source of infection, hepatitis A patient only discharges pathogen from feces, in blood, HAV mainly appears on first 14-21 days of jaundice generation, in this phase, the blood of patient is infectious, have been reported that by Transfusion Transmission, but after jaundice occurs, patient's blood is usual without infectiousness.Patient before onset 2 weeks and to play the quantity discharging HAV after being ill for 1 week from feces maximum, now infectiousness is the strongest, but within 30 days after being ill, still has small part patient to discharge HAV from feces to rising.Hepatitis A is with fecal-oral route for major transmission path, the mode that excrement oral instructions are broadcast is various, generally, Rountine contiguity spread is the main mode of transmission of sporadic occurrence, therefore at collective's unit such as Kindergartens, in school and army, hepatitis A sickness rate is high, and the propagation of water and food, particularly aquatic shellfish such as Scapharca subcrenata etc. are the main mode of transmissions of hepatitis A eruption and prevalence.
At present, for the domestic interfering effects of drug extract for treating adopted for the treatment of hepatitis A more, but side effect is big, expensive, long term injections brings very big misery to patient, and hepatitis A infects everywhere, endanger the health of human body at any time, although having succeeded in developing the vaccine of prevention hepatitis A, but this is simply in prevention, also has certain time limit.For this, develop a kind of can one of the medicine important topic becoming medical research of fast treating hepatitis A.
Summary of the invention
The invention provides a kind of medicine treating hepatitis A and preparation method；Selected by medicine of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of soothing the liver, the dissolving blood stasis and detoxication of nourishing blood, heat clearing away of invigorating blood circulation, treatment hepatitis A is had significant curative effect and short treating period, instant effect, non-relapse after healing, safe without toxic side effect, it is possible to increase immunity of organisms, special effect is practical, wide popularization and application on clinic.
For achieving the above object, technical scheme is implemented as follows:
A kind of medicine treating hepatitis A, make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of medicine treating hepatitis A, comprises the following steps that:
(1) Fructus Herpetospermi pedunculosi, Radix Serissae, Herba Gentianopsis Paludosae, Semen Platycladi, Ramulus Salicis Babylonicae, Conyza canadensis (L.) Cronq., Fructus Trichosanthis, Caulis et Folium Abri, dish, Fructus Schisandrae Chinensis and Fructus Forsythiae are cleaned, put into container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount distilled water, boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hour, extract；Merging three extracting solution, filter, obtain filtrate, being condensed at 60 DEG C relative density is the thick paste of 1.10～1.13, standby；
(2) Mesona chinensis Benth is cleaned, immerse 5 times amount 60% alcohol solution dipping 1～2 hour, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby；
(3) Herba Cirsii, Rhizoma Nelumbinis, Fructus Fici and Rhizoma Phragmitis are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(4) after the thick paste obtained by above-mentioned steps (1)～(3) and juice being mixed, make tablet, obtain the medicine of described treatment hepatitis A.
The property of medicine of Chinese medicine used by the present invention is as follows:
Fructus Herpetospermi pedunculosi: cold in nature, bitter in the mouth.Heat-clearing and toxic substances removing, easing the affected liver.Control icteric infectious hepatitis, dyspepsia.
Radix Serissae: bitter in the mouth, pungent, cool in nature；Return liver, spleen channel.Expelling wind and removing dampness, heat-clearing and toxic substances removing.Cure mainly flu, icterohepatitis, oedema due to nephritis, cough, laryngalgia, keratitis, enteritis, dysentery, lumbago and skelalgia, hemoptysis, hematuria, women's amenorrhea, leucorrhea, infantile malnutrition, infantile convulsion, acute toothache, swollen ulcer drug, traumatic injury." Guizhou folk medicine " carries: " heat-clearing and toxic substances removing, soothing the channels and quicking the network vessels.Control knife injury, paralysis, the weak disease of men and women, fly furuncle.”
Mesona chinensis Benth: there is clearing away summer-heat, the function of antipyretic diuretic.Cure mainly heatstroke, pyretic toxicity, quench one's thirst, hypertension, nephropathy, diabetes, pain of joint muscle, gonorrhea etc..Modern medicine study confirms, in Mesona chinensis Benth's ingredient, Flavonoid substances has the effect suppressing cancer cell growth, reducing blood pressure；Polysaccharide has enhancing and improves human body immune function effect；Essence have calmness, refrigerant, removing toxic substances, diuretic effect；Trace element has suppression free radical formation, defying age, anticancer effect；Vitamin can regulate and strengthen physiological function etc..
Herba Gentianopsis Paludosae: bitter in the mouth, cold in nature；GUIXIN, Liver Channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Main fever caused by exogenous pathogens, hepatitis, cholecystitis, conjunctival congestion of having a headache, wound swells and ache, furuncle toxic swelling.
Semen Platycladi: sweet in the mouth, property is put down；GUIXIN, kidney, large intestine channel.Tranquilizing by nourishing the heart, hidroschesis intestine moistening.Have a sleepless night for fidgets due to deficiency, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation." detailed outline " carries: " nourish heart gas, and profit kidney is dry, and Fructus Alpiniae Oxyphyllae is allayed excitement；Burn drop and control scabies.”
Ramulus Salicis Babylonicae: bitter in the mouth, cold in nature, nontoxic；Enter foot bright, the JUE YIN meridian of sun.Dispel the wind diuresis, alleviating pain and detumescence.Cure mainly rheumatic arthralgia, gonorrhea, nebulousurine, urinary obstruction, infectious hepatitis, swelling due to wind, furuncle, erysipelas, dental caries, swelling of the gum." this sketch of the southern regions of the Yunnan Province is said " carries: " cure mainly the blood clotting stagnation of QI, the exterior tightened by pathogenic windcold；Children's's variola, has Aconitum carmichjaelii Debx. to fall into top, and slurry can not rise person, decoction or bathe it.”
Conyza canadensis (L.) Cronq.: mildly bitter flavor, pungent, cool in nature.Clearing away heat-damp and promoting diuresis, dissipating blood stasis for subsidence of swelling.Enteritis and dysentery, infectious hepatitis, cholecystitis；Psoriasis, traumatic injury, furuncle toxic swelling, rheumatic ostalgia, traumatic hemorrhage are controlled in external；Fresh leaf is smash juice and is controlled otitis media, eye conjunctivitis.
Fructus Trichosanthis: sweet in the mouth, micro-hardship, cold in nature；Return lung, stomach, large intestine channel.Moistening the lung and resolving phlegm, eliminating stagnation laxation.Control phlegm-heat cough, the thoracic obstruction, blocked-up chest, consumptive lung disease hemoptysis, quench one's thirst, jaundice, constipation, carbuncle from the beginning of." detailed outline " carries: " lung moistening is dry, pathogenic fire reducing.Controlling cough, clearing away phlegm is tied, throat, subduing inflammation sore.”
Herba Cirsii: sweet in the mouth, hardship, cool in nature；GUIXIN, Liver Channel.Cooling blood for hemostasis, removing blood stasis to reduce swelling.For epistaxis, spit blood, hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus." Chinese herbal medicine is commonly used in Shanghai " carries: " heat clearing away, hemostasis, blood pressure lowering, dissipating blood stasis for subsidence of swelling.Control various hemorrhage, hypertension, jaundice, hepatitis, nephritis.”
Caulis et Folium Abri: sweet in the mouth, cool in nature, nontoxic；Return lung, spleen, Liver Channel.Promote the production of body fluid, lung moistening, heat clearing away, diuresis, cure mainly laryngalgia, hepatitis, bronchitis." Guangxi Chinese herbal medicine " carries: " clearing away heat and promoting diuresis.Control laryngopharynx swelling and pain, hepatitis, bronchitis.”
Rhizoma Nelumbinis: sweet in the mouth, cool in nature, main invigorating middle warmer is burnt, reposes, physical strength profiting.Energy clearing away heat and promoting production of body fluid, cooling blood for hemostasis, dissipating blood stasis blood." traditional Chinese medical science " carries: " repose, physical strength profiting." modern medicine study confirmation, the nutritive value of Rhizoma Nelumbinis is significantly high, and rich in the trace element such as ferrum, calcium, phytoprotein, vitamin and content of starch are also very abundant, has obvious benefiting vital QI and blood, strengthens body immunity effect.
Dish: sweet in the mouth, light, cool in nature.Heat-clearing and toxic substances removing, antitussive, diuresis.For cold, fever, laryngopharynx swelling and pain, cough due to lung-heat, chronic tracheitis, acute rheumatic arthritis, hepatitis, dysuria；Dermatitis rhus, venom, furuncle carbuncle are controlled in external.Guangzhou army " conventional Chinese herbal medicine handbook " load: " clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure cold heating, laryngopharynx swelling and pain, aphonia, cough due to lung-heat, hemoptysis, acute rheumatic arthritis, edema.”
Fructus Schisandrae Chinensis: sour in the mouth, property is sweet；Return lung, the heart, kidney channel.Astringe the lung nourishing kidney, receipts of promoting the production of body fluid antiperspirant, arresting seminal emission.Fructus Schisandrae Chinensis can protect human five internal organs's heart, liver, spleen, lung, kidney, and the energy strong liver of QI invigorating, the promotion detoxification processes of liver, the liver protecting are from murder by poisoning, and the liver organization of energy regeneration of damaged.
Fructus Forsythiae: bitter in the mouth, cold nature；Return lung, the heart, gallbladder meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens.Curing mainly carbuncle sore tumefacting virus, sucutaneous nodule scrofula, affection due to external wind and heat, epidemic febrile disease is from the beginning of, the puckery pain of pyretic stranguria etc.." herbal classic " carries: " main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat." modern medicine study confirmation, Fructus Forsythiae concentrated decotion has antibacterial action in vitro, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc..
Fructus Fici: sweet in the mouth, cool in nature；Return lung, stomach, large intestine channel.Invigorating the stomach and promoting bowel movement, subduing swelling and detoxicating.Control enteritis, dysentery, constipation, hemorrhoid, laryngalgia, ulcerative carbuncle scabies, throat, anthelmintic of whetting the appetite.For inappetence, abdominal distention, constipation due to hemorrhoids, dyspepsia, hemorrhoid, proctoptosis, diarrhoea, hypogalactia, laryngopharynx swelling and pain, hematodiarrhoea, the disease such as cough ant phlegm." Yunnan Chinese herbal medicine " carries: " stomach invigorating antidiarrheal, eliminates the phlegm and regulate the flow of vital energy.Control inappetence, dyspepsia, enteritis, dysentery, throat pain, cough with copious phlegm, uncomfortable in chest.”
Rhizoma Phragmitis: sweet in the mouth, cold in nature；Attach to the lung and stomach meridians.Clearing away heat and promoting production of body fluid, relieves restlessness and prevents vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria." Nanjing medicinal herbs among the people " carry: " soothe sore throat.”
The present invention compared with prior art, has the advantages that
Selected by medicine of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of soothing the liver, the dissolving blood stasis and detoxication of nourishing blood, heat clearing away of invigorating blood circulation, treatment hepatitis A is had significant curative effect and short treating period, instant effect, non-relapse after healing, safe without toxic side effect, it is possible to increase immunity of organisms, special effect is practical, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
The preparation method of a kind of medicine treating hepatitis A, comprises the following steps that:
(1) Fructus Herpetospermi pedunculosi, Radix Serissae, Herba Gentianopsis Paludosae, Semen Platycladi, Ramulus Salicis Babylonicae, Conyza canadensis (L.) Cronq., Fructus Trichosanthis, Caulis et Folium Abri, dish, Fructus Schisandrae Chinensis and Fructus Forsythiae are cleaned, put into container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount distilled water, boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hour, extract；Merging three extracting solution, filter, obtain filtrate, being condensed at 60 DEG C relative density is the thick paste of 1.10～1.13, standby；
(2) Mesona chinensis Benth is cleaned, immerse 5 times amount 60% alcohol solution dipping 1～2 hour, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby；
(3) Herba Cirsii, Rhizoma Nelumbinis, Fructus Fici and Rhizoma Phragmitis are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(4) after the thick paste obtained by above-mentioned steps (1)～(3) and juice being mixed, make tablet, obtain the medicine of described treatment hepatitis A.
Usage and dosage: oral, every day 3 times, each 1 time of morning, noon and afternoon, each 2 (every 0.5g), ante cibum warm water delivery service；Within 5 days, being 1 course for the treatment of, 4～6 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 5
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Clinical data:
1, case selection:
As the medicine for the treatment of hepatitis A, selecting the hepatitis A patient 170 example clinical observation made a definite diagnosis, patient is randomly divided into treatment group and matched group two groups, treatment group 85 example, wherein male 43 example, women 42 example, 14～41 years old age, 27.5 years old mean age, average course of disease 20 days；Matched group 85 example, wherein male 42 example, women 43 example, 15～40 years old age, 27.5 years old mean age, average course of disease 20 days.
Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 3 times, each 1 time of morning, noon and afternoon, each 2 (every 0.5g), ante cibum warm water delivery service；Within 5 days, being 1 course for the treatment of, 4～6 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes Qi Moxin thymosin enteric coatel tablets, oral, each 5～30mg, 1～3 time on the one or follow the doctor's advice.
3, efficacy determination:
(1) curing: clinical symptoms all disappears, lab index recovers normal.
(2) effective: clinical symptoms substantially alleviates, lab index is clearly better.
(3) effective: clinical symptoms alleviates to some extent, and lab index takes a turn for the better to some extent.
(4) invalid: not alleviated by clinical symptoms after treating, lab index is without improvement.
4, result:
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Jiang, man, 16 years old, people from Wansheng District, Chongqing.Patient because of heating, loss of appetite, nausea and vomiting, without obvious inducement heating reach 38 DEG C, remove hospital admission, it is hepatitis A through diagnosis, gives Drug therapy of the present invention through doctor, after taking 3 courses for the treatment of, symptom is alleviated to some extent, burning is moved back, and after taking 2 courses for the treatment of, symptom all disappears, recovery from illness, after 3 months, check is without recurrence.
2, Cai, female, 20 years old, people from Handan, Hebei.Patient's loss of appetite, nausea and vomiting, weak, hepatomegaly and abnormal liver function, sick just often have heating, removes examination in hospital, is diagnosed as hepatitis A, through taking Drug therapy of the present invention, after taking 2 courses for the treatment of, symptom takes a turn for the better to some extent, after taking 2 courses for the treatment of, transference cure, recovery from illness.
3, certain is gone into business, man, 24 years old, people from Shuangyashan, Heilungkiang.Patient's right flank portion dull pain is uncomfortable, nausea of feeling sick, yellow urine, stool is normal, and red tongue tongue is greasy in vain, slippery and rapid pulse, diagnosis is hepatitis A, uses Drug therapy, and the state of an illness has no improvement, taking Drug therapy of the present invention, after taking 2 courses for the treatment of, symptom substantially alleviates, after continuing to take 3 courses for the treatment of, transference cure, recovery from illness, after 1 month, check is without recurrence.
4, fourth, female, 19 years old, jiangsu wuxi people.Patient is unable because of anorexia, and companion's xanthochromia occurs together heat, time have right flank portion dull pain uncomfortable, nauseating nausea, removes hospital admission, diagnoses as hepatitis A, use injectable drug is treated, have no any improvement, through taking Drug therapy of the present invention, after taking 3 courses for the treatment of, symptom alleviates, after taking 3 courses for the treatment of, symptom all disappears, recovery from illness.
5, Wei, man, 26 years old, Xuancheng Profile, anhui Province people.Patient's legs and feet are heavy, feel run-down, inappetence, with the symptom of low grade fever and nausea and vomiting, go hospital's blood test to suffer from hepatitis A, give Drug therapy of the present invention through doctor, after taking 3 courses for the treatment of, remission, after taking 2 courses for the treatment of, transference cure, recovery from illness.
6, Xue, female, 31 years old, Bay, Ningde, Fujian Province people.Patients ' vomiting, abdominal distention are weak, inappetence, loss of appetite, detest oil, sometimes with heating paresthesia, use Drug therapy, therapeutic effect is general, through taking Chinese medicine preparation of the present invention treatment, after taking 3 courses for the treatment of, symptom substantially alleviates, after continuing to take 2 courses for the treatment of, transference cure, recovery from illness, after half a year, check is without recurrence.

Claims (5)

1. the medicine treating hepatitis A, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
56～80 parts of Radix Serissae of Fructus Herpetospermi pedunculosi, 54～78 parts of Herba Gentianopsis Paludosae of 55～79 parts of Mesona chinensis Benths 54～78 parts
53～77 parts of Ramulus Salicis Babylonicaes of Semen Platycladi, 52～76 parts of Fructus Trichosanthiss of 53～77 parts of Conyza canadensis (L.) Cronq.s 51～75 parts
51～75 portions of Caulis et Folium Abries of Herba Cirsii, 49～73 portions of dishes of 50～74 parts of Rhizoma Nelumbiniss 49～73 parts
49～73 parts of Fructus Forsythiaes of Fructus Schisandrae Chinensis, 45～69 parts of Rhizoma Phragmitiss of 48～71 parts of Fructus Ficis 45～69 parts.
2. a kind of medicine treating hepatitis A according to claim 1, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
60～76 parts of Radix Serissae of Fructus Herpetospermi pedunculosi, 58～74 parts of Herba Gentianopsis Paludosae of 59～75 parts of Mesona chinensis Benths 58～74 parts
57～73 parts of Ramulus Salicis Babylonicaes of Semen Platycladi, 56～72 parts of Fructus Trichosanthiss of 57～73 parts of Conyza canadensis (L.) Cronq.s 55～71 parts
55～71 portions of Caulis et Folium Abries of Herba Cirsii, 53～69 portions of dishes of 54～70 parts of Rhizoma Nelumbiniss 53～69 parts
53～69 parts of Fructus Forsythiaes of Fructus Schisandrae Chinensis, 49～65 parts of Rhizoma Phragmitiss of 51～67 parts of Fructus Ficis 49～65 parts.
3. a kind of medicine treating hepatitis A according to claim 1, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
64～72 parts of Radix Serissae of Fructus Herpetospermi pedunculosi, 62～70 parts of Herba Gentianopsis Paludosae of 63～71 parts of Mesona chinensis Benths 62～70 parts
61～69 parts of Ramulus Salicis Babylonicaes of Semen Platycladi, 60～68 parts of Fructus Trichosanthiss of 61～69 parts of Conyza canadensis (L.) Cronq.s 59～67 parts
59～67 portions of Caulis et Folium Abries of Herba Cirsii, 57～65 portions of dishes of 58～66 parts of Rhizoma Nelumbiniss 57～65 parts
57～65 parts of Fructus Forsythiaes of Fructus Schisandrae Chinensis, 53～61 parts of Rhizoma Phragmitiss of 55～63 parts of Fructus Ficis 53～61 parts.
4. a kind of medicine treating hepatitis A according to claim 1, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
68 parts of Radix Serissae of Fructus Herpetospermi pedunculosi, 66 parts of Herba Gentianopsis Paludosae of 67 parts of Mesona chinensis Benths 66 parts
65 parts of Ramulus Salicis Babylonicaes of Semen Platycladi, 64 parts of Fructus Trichosanthiss of 65 parts of Conyza canadensis (L.) Cronq.s 63 parts
63 portions of Caulis et Folium Abries of Herba Cirsii, 61 portions of dishes of 62 parts of Rhizoma Nelumbiniss 61 parts
61 parts of Fructus Forsythiaes of Fructus Schisandrae Chinensis, 57 parts of Rhizoma Phragmitiss of 59 parts of Fructus Ficis 57 parts.
5. the preparation method of the medicine treating hepatitis A as described in any one of Claims 1 to 4, it is characterised in that: comprise the following steps that:
(1) Fructus Herpetospermi pedunculosi, Radix Serissae, Herba Gentianopsis Paludosae, Semen Platycladi, Ramulus Salicis Babylonicae, Conyza canadensis (L.) Cronq., Fructus Trichosanthis, Caulis et Folium Abri, dish, Fructus Schisandrae Chinensis and Fructus Forsythiae are cleaned, put into container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount distilled water, boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hour, extract；Merging three extracting solution, filter, obtain filtrate, being condensed at 60 DEG C relative density is the thick paste of 1.10～1.13, standby；
(2) Mesona chinensis Benth is cleaned, immerse 5 times amount 60% alcohol solution dipping 1～2 hour, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby；
(3) Herba Cirsii, Rhizoma Nelumbinis, Fructus Fici and Rhizoma Phragmitis are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(4) after the thick paste obtained by above-mentioned steps (1)～(3) and juice being mixed, make tablet, obtain the medicine of described treatment hepatitis A.
CN201610207112.3A 2016-04-05 2016-04-05 Medicine for treating viral hepatitis A and preparation method Pending CN105749002A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102240342A (en) * 2011-08-11 2011-11-16 沈信堂 Traditional Chinese medicine for treating viral hepatitis A
CN103961448A (en) * 2014-05-19 2014-08-06 赵海苹 Traditional Chinese medicine preparation for treating hepatitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102240342A (en) * 2011-08-11 2011-11-16 沈信堂 Traditional Chinese medicine for treating viral hepatitis A
CN103961448A (en) * 2014-05-19 2014-08-06 赵海苹 Traditional Chinese medicine preparation for treating hepatitis and preparation method thereof

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Application publication date: 20160713