CN105747214A - Branched-chain amino acid composition - Google Patents
Branched-chain amino acid composition Download PDFInfo
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- CN105747214A CN105747214A CN201610106150.XA CN201610106150A CN105747214A CN 105747214 A CN105747214 A CN 105747214A CN 201610106150 A CN201610106150 A CN 201610106150A CN 105747214 A CN105747214 A CN 105747214A
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- amino acid
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- chain amino
- acid composition
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Abstract
The invention provides a branched-chain amino acid composition. The branched-chain amino acid composition is prepared from a branched-chain amino acid, cysteine, VC and selenium-enriched yeast powder. The composition prepared by the invention can be used for promoting muscle growth, optimizing a muscle/fat ratio and reducing the catabolism of muscle; and meanwhile, the accumulation of free radicals in a body after exercises can also be effectively cleaned and body fluid electrolyte can be rapidly supplemented. The branched-chain amino acid composition has the effects of improving the sports results, rapidly recovering the physical strength after the exercises and reducing sports injuries.
Description
Technical field
The present invention relates to dietary supplement field, specifically, relate to a kind of branched-amino acid composition and application thereof.
Background technology
Branched-chain amino acid (BranchedChainAminoAcids, BCAAs) is as essential amino acid, on the one hand, suitably supplements and can reduce the catabolism of protein in muscle, and promote glyconeogenesis, it is possible to improves strength and anaerobic sport capacity；On the other hand, branched-chain amino acid oxidation Decomposition in vivo produces the efficiency of ATP higher than other aminoacid, supplementary BCAA can effectively reduce the formation of 5-hydroxy tryptamine (5-HT), weakens the feeling of fatigue that human feeling arrives, and provides energy and will to ensure for the long-time endurance exercise of body.
The main Physiological Function of branched-chain amino acid is as follows:
Composition muscle: the BCAA ingredient that to be not only in muscle amino acid maximum, is also unique aminoacid of metabolism in muscle.
Offer energy: BCAA is the primary amino acid of human muscle's energy supply.Its oxidation energy supply accounts for the 60% of aminoacid energy supply total amount.Even if BCAA oxidation energy supply has also reached 14% in resting state, muscle, when prolonged exercise, it can be the direct energy supply of muscle in training.
Increase muscle: supplementing BCAA during training can discharge by stimulating growth hormone, improves insulin level, thus playing the effect promoting muscle synthesis.
Protection muscle: in motor process, supplements enough BCAA and can promote the synthesis of postexercise recovery phase protein, reduce the decomposition of muscular tissue, protect muscular tissue.
Weaken feeling of fatigue: supplementary BCAA be possible to prevent to take exercise after the decline of BCAA content in serum.In serum, the decline of BCAA content can cause the tryptophan conveying to head, thus producing 5-hydroxyl color ammonia at head, the latter can cause feeling of fatigue.
Free radical is the charged group with active proton that human body cell produces due to metabolism and defense response.The free radical meeting damaging cells produced owing to coercing, accelerates cell ageing.After human motion, exercise and physical work, substantial amounts of free radical all can be caused to produce and accumulation.The free radical scavenger being currently known includes vitamin C, selenium and glutathion etc..Cysteine itself has antioxidant activity, is also the precursor substance of human body cell generation glutathion simultaneously.Fructus Citri Limoniae is enriched in the nutrition of multivitamin (particularly VC) and the fruit that medical value is all very high, and it is rich in substantial amounts of electrolyte, organic acid and bioactive substances such as vitamin C, saccharide, calcium, phosphorus, ferrum, vitamin B1, vitamin B2, nicotinic acid, quininic acid, citric acid, malic acid, Hesperidin, naringin, coumarin, a large amount potassium element and low amounts sodium elements.Citric acid has the effect preventing and eliminating cutaneous pigmentation.Vitamin A in Fructus Citri Limoniae, C, P, after skin absorption, can make skin keep gorgeous, and gloss is fine and smooth.In yeast rich in selenium except containing balanced aminoacid, possibly together with abundant vitamin B group, the latter is not only the nutrient substance of needed by human, also can work in coordination with the help human body absorption to BCAA simultaneously.
The problem that presently, there are: the BCAAs product component that currently there are is single, except keeping protein anabolism, it is prevented that outside catabolism, a large amount of free radicals of generation and the electrolyte made up with perspiration loss after motion can not be removed.
Summary of the invention
For current BCAAs supplement component and function singleness, it is impossible to effectively remove a large amount of free radicals produced in motion or physical work and supplement a large amount of electrolytical defect run off in motion.The invention provides a kind of branched-amino acid composition.
Technical scheme is as follows:
A kind of branched-amino acid composition of the present invention, is prepared from by the component of following weight portion:
Cysteine: 1～10；
VC:0.5～4；
Yeast rich in selenium powder: 2～15；
Citron extract: 2～15；
Leucine: 35～40；
Isoleucine: 15～20；
Valine: 15～20.
Mix above raw material, adopt conventional method to prepare into the applicable dosage forms such as electuary, tablet, capsule or chewable tablet.
The present invention adds cysteine, vitamin C, organic selenium to strengthen the free radical scavenging activity of these supplement on the basis of traditional B CAA compositions.Meanwhile, natural complex B race is introduced with the form of yeast rich in selenium, to be conducive to the absorption of branched-chain amino acid.Simultaneously each seed amino acid in yeast rich in selenium and citron extract, vitamin and electrolyte, trace element etc., also can supplement the various electrolyte ingredients with perspiration discharge in motion to a certain extent.
Provided by the inventionCompositions can promote muscle to increase, optimize muscle/fat ratio, reduces the catabolism of muscle, simultaneously, moreover it is possible to the effectively accumulation of interior free yl after removing motion, quickly supplements fluid electrolyte.The effect of the athletic injury that quickly regains one's strength after improving sports achievement and motion, reduces can be played.
Detailed description of the invention
Following example are only intended to the present invention is described, are not used for limiting the range of application of the present invention.
Embodiment 1
Weigh leucine 20kg, isoleucine 9kg, valine 10.5kg respectively, vitamin C 1kg, cysteine 1kg, yeast rich in selenium powder 4kg, citron extract 4.5kg, Pulvis Talci 0.2kg, pulverize, mixing, pour in the filling mould of capsule filling machine, fill, obtains the branched-chain amino acid composition capsule of the present invention.
Every capsule weight 500mg, 3 capsules are 1 time, every day 2 times, or each 6 capsules when needing.
Embodiment 2
Weigh leucine 40kg, isoleucine 20kg, valine 18kg, Catergen kg respectively, cysteine 1kg, yeast rich in selenium powder 8kg, citron extract 9kg, white sugar 15kg, cross 80 mesh sieves, mix homogeneously in dry-mixed machine after pulverizing, obtain powder of the present invention or solid beverage.It is 1 part that this solid beverage takes 15～20 grams every time, reconstitutes with the hot water of about 60～80mL80 DEG C,.
Embodiment 3
Weigh leucine 76kg, isoleucine 40kg, valine 34kg respectively, cysteine 4kg, vitamin C 4kg, yeast rich in selenium powder 14kg, citron extract 16kg, CMC-Na2.4kg, modified starch 6kg, cross 80 mesh sieves after pulverizing, mix homogeneously in dry-mixed machine, make binding agent with the alcoholic solution of 70%, prepare soft material, the wet grain of 20 mesh sieve systems of crossing.Wet grain is placed in 60 DEG C of oven dryings 5～6 hours, crosses 20 mesh sieves, prepare dry granule, add magnesium stearate 3kg, silicon dioxide 0.6kg, mix homogeneously, tabletting in tablet machine, prepare oral tablet.
Embodiment 4
Weigh leucine 72kg, isoleucine 34kg, valine 38kg respectively, Cys2 kg, Catergen kg, yeast rich in selenium powder 10kg, citron extract 10kg, high fructose syrup (80%) 22 liter, CMC-Na2.4kg, modified starch 6kg, cross 80 mesh sieves, mix homogeneously in dry-mixed machine after pulverizing, make binding agent with the alcoholic solution of 70%, prepare soft material, the wet grain of 20 mesh sieve systems of crossing.Wet grain is placed in 60 DEG C of oven dryings 5～6 hours, crosses 20 mesh sieves, prepare dry granule, add magnesium stearate 3kg, silicon dioxide 0.6kg, tabletting in tablet machine, prepare this product chewable tablet.
Branched-amino acid composition of the present invention can according to the conventional method of this area, add functional auxiliary materials (such as magnesium stearate, silicon dioxide, starch, hypromellose, coloring agent, white sugar, high fructose syrup, acesulfame potassium, xylitol etc.) well known in the art and make the patterns such as pressed candy, oral tablet, granule, capsule, pressed powder, to be convenient to carry and eat.
Branched-chain amino acid composition article of the present invention is applicable to athlete, vigorous and graceful personage, the crowd that goes on a diet, vegetarian and the travelling fan often gone out, there is the function promoting and keeping muscle quality, simultaneously can effective scavenging free radicals, alleviate and postpone fatigue, contributing to antisecosis.
The sequencing of above example only for ease of describing, does not represent the quality of embodiment.
What deserves to be explained is, above example is only in order to illustrate technical scheme, but not technical scheme is limited；Although the present invention being described in detail with reference to previous embodiment, it will be understood by those within the art that: the technical scheme described in foregoing embodiments still can be carried out parameter modification by it, or wherein portion of techniques feature carries out equivalent or similar replacement；And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (1)
1. a branched-amino acid composition, it is characterised in that be prepared from by the component of following weight portion:
Cysteine: 1～10；
VC:0.5～4；
Yeast rich in selenium powder: 2～15；
Citron extract: 2～15；
Leucine: 35～40；
Isoleucine: 15～20；
Valine: 15～20.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108042634A (en) * | 2018-01-24 | 2018-05-18 | 江苏神华药业有限公司 | A kind of composition with effects of dispelling effects of alcohol and protecting liver and preparation method thereof |
| CN110754558A (en) * | 2018-12-22 | 2020-02-07 | 广东永青生物科技有限公司 | Fructose energy chewable tablets prepared by taking crystalline fructose as main energy raw material |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1422125A (en) * | 2000-04-12 | 2003-06-04 | 雀巢制品公司 | Composition comprising free amino acids |
| CN101316582A (en) * | 2005-11-30 | 2008-12-03 | 雀巢技术公司 | Methods for the treatment of muscle loss |
| CN104906051A (en) * | 2015-07-01 | 2015-09-16 | 深圳劲创生物技术有限公司 | Nutrient granules and preparation method thereof |
| CN105192512A (en) * | 2015-10-14 | 2015-12-30 | 北京康比特体育科技股份有限公司 | Composition for improving antioxidant capacity of human bodies in movement |
-
2016
- 2016-02-26 CN CN201610106150.XA patent/CN105747214A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1422125A (en) * | 2000-04-12 | 2003-06-04 | 雀巢制品公司 | Composition comprising free amino acids |
| CN101316582A (en) * | 2005-11-30 | 2008-12-03 | 雀巢技术公司 | Methods for the treatment of muscle loss |
| CN104906051A (en) * | 2015-07-01 | 2015-09-16 | 深圳劲创生物技术有限公司 | Nutrient granules and preparation method thereof |
| CN105192512A (en) * | 2015-10-14 | 2015-12-30 | 北京康比特体育科技股份有限公司 | Composition for improving antioxidant capacity of human bodies in movement |
Non-Patent Citations (1)
| Title |
|---|
| 李世成: "《运动时间营养学——生物节律与运动员择时营养》", 31 May 2007 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108042634A (en) * | 2018-01-24 | 2018-05-18 | 江苏神华药业有限公司 | A kind of composition with effects of dispelling effects of alcohol and protecting liver and preparation method thereof |
| CN110754558A (en) * | 2018-12-22 | 2020-02-07 | 广东永青生物科技有限公司 | Fructose energy chewable tablets prepared by taking crystalline fructose as main energy raw material |
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