CN105744946A - 人分泌球蛋白的修饰和新型组合物 - Google Patents

人分泌球蛋白的修饰和新型组合物 Download PDF

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Publication number
CN105744946A
CN105744946A CN201480015618.3A CN201480015618A CN105744946A CN 105744946 A CN105744946 A CN 105744946A CN 201480015618 A CN201480015618 A CN 201480015618A CN 105744946 A CN105744946 A CN 105744946A
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CN
China
Prior art keywords
composition
synthesized
rhcc10
chemically
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480015618.3A
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English (en)
Chinese (zh)
Inventor
爱普瑞·L·皮隆
哈姆恰·K·哈里普拉卡什
理查德·S·克莱顿
梅莉莎·E·温
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THERABRON THERAPEUTICS Inc
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THERABRON THERAPEUTICS Inc
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Application filed by THERABRON THERAPEUTICS Inc filed Critical THERABRON THERAPEUTICS Inc
Publication of CN105744946A publication Critical patent/CN105744946A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyrrole Compounds (AREA)
CN201480015618.3A 2013-03-15 2014-03-17 人分泌球蛋白的修饰和新型组合物 Pending CN105744946A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/843,773 US9394349B2 (en) 2013-03-15 2013-03-15 Modification and compositions of human secretoglobin proteins
US13/843773 2013-03-15
PCT/US2014/030117 WO2014145368A2 (en) 2013-03-15 2014-03-17 Modification and novel compositions of human secretoglobin proteins

Publications (1)

Publication Number Publication Date
CN105744946A true CN105744946A (zh) 2016-07-06

Family

ID=51530119

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480015618.3A Pending CN105744946A (zh) 2013-03-15 2014-03-17 人分泌球蛋白的修饰和新型组合物

Country Status (13)

Country Link
US (4) US9394349B2 (https=)
EP (2) EP2968449A4 (https=)
JP (2) JP6670987B2 (https=)
KR (1) KR20160030076A (https=)
CN (1) CN105744946A (https=)
AU (1) AU2014233127A1 (https=)
BR (1) BR112015021266A2 (https=)
CA (1) CA2907439A1 (https=)
IL (1) IL241417A0 (https=)
MX (1) MX2015013092A (https=)
RU (1) RU2015144360A (https=)
SG (1) SG11201507277YA (https=)
WO (1) WO2014145368A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12162914B2 (en) 2013-03-15 2024-12-10 Apc Research Assets Llc Modification and compositions of human secretoglobin proteins
US9394349B2 (en) * 2013-03-15 2016-07-19 Therabron Therapeutics, Inc. Modification and compositions of human secretoglobin proteins
JP2018502850A (ja) * 2014-12-22 2018-02-01 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗原、抗体を作成するための組成物及び方法、ならびに免疫療法のための組成物及び方法
US20180325931A1 (en) 2017-01-21 2018-11-15 Ningbo Zhiming Biotechnology Co., Ltd. Use of paeoniflorin-6'-o-benzenesulfonate in treatment of sjögren's syndrome
JP2022509856A (ja) * 2018-11-30 2022-01-24 エーピーシー リサーチ アセッツ，エルエルシー ヘパラン硫酸プロテオグリカンタンパク質との相互作用を介してグリコカリックスを保護するためのセクレトグロビンの組成物及び使用方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030008816A1 (en) * 1997-05-28 2003-01-09 Pilon Aprile L. Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
CN1580261A (zh) * 2003-08-06 2005-02-16 上海富纯中南生物技术有限公司 Cc10蛋白的制备及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1006919A3 (nl) * 1993-03-15 1995-01-24 Ley Marc Jozef Philemon De Farmaceutisch preparaat op basis van clara celeiwit cc10, en het gebruik daarvan als geneesmiddel en diagnosticum.
US20060281681A1 (en) 1997-05-28 2006-12-14 Pilon Aprile L Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease
US20040047857A1 (en) * 1997-05-28 2004-03-11 Pilon Aprile L. Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
WO2000009741A1 (en) 1998-08-13 2000-02-24 The Trustees Of The University Of Pennsylvania Method of identifying proteins
US6953666B1 (en) 1998-11-06 2005-10-11 Emory University Biomarkers for oxidative stress
WO2004101824A1 (ja) 2003-05-14 2004-11-25 Shionogi & Co., Ltd. 慢性閉塞性肺疾患の検出方法
AU2004254600A1 (en) 2003-06-26 2005-01-13 Lifesensors, Inc. Methods and compositions for enhanced protein expression and purification
JP2007511517A (ja) 2003-11-14 2007-05-10 アルザ・コーポレーシヨン 薬剤と照射を受けた賦形剤の製剤の中の薬剤の酸化を最小化
US20060275794A1 (en) 2005-03-07 2006-12-07 Invitrogen Corporation Collections of matched biological reagents and methods for identifying matched reagents
US8133859B2 (en) 2006-09-27 2012-03-13 The United States Of America As Represented By The Department Of Health And Human Services SCGB3A2 as a growth factor and anti-apoptotic agent
US20090004684A1 (en) 2007-05-23 2009-01-01 Claudia Susanne Maier Compositions and Methods for Detection and Quantification of Protein Oxidation
MX2012004409A (es) * 2009-10-15 2012-08-23 Clarassance Inc Proteina recombinante de humano cc10 para el tratamiento de la influenza.
US9394349B2 (en) * 2013-03-15 2016-07-19 Therabron Therapeutics, Inc. Modification and compositions of human secretoglobin proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030008816A1 (en) * 1997-05-28 2003-01-09 Pilon Aprile L. Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
CN1580261A (zh) * 2003-08-06 2005-02-16 上海富纯中南生物技术有限公司 Cc10蛋白的制备及应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GIANNONE PJ等: "Oxidative modifications of recombinant human Clara Cell Secretory Protein (rhCC10) by myeloperoxidase (MPO) and HOCI in vitro", 《PEDIATRIC RESEARCH》 *
JOEL ARIAS-MARTINEZ等: "Clara Cell Protein Expression in Human Neonates During Respiratory Distress Syndrome", 《CELLULAR PHYSIOLOGY AND BIOCHEMISTRY》 *

Also Published As

Publication number Publication date
JP2020055833A (ja) 2020-04-09
US10676513B2 (en) 2020-06-09
CA2907439A1 (en) 2014-09-18
EP2968449A4 (en) 2017-03-22
JP2016515532A (ja) 2016-05-30
SG11201507277YA (en) 2015-10-29
US10294285B2 (en) 2019-05-21
US20140275477A1 (en) 2014-09-18
EP3403666A1 (en) 2018-11-21
AU2014233127A1 (en) 2015-09-24
WO2014145368A2 (en) 2014-09-18
US9394349B2 (en) 2016-07-19
IL241417A0 (en) 2015-11-30
BR112015021266A2 (pt) 2017-10-10
US20200325190A1 (en) 2020-10-15
US20160362462A1 (en) 2016-12-15
JP6670987B2 (ja) 2020-03-25
MX2015013092A (es) 2016-06-02
KR20160030076A (ko) 2016-03-16
EP2968449A2 (en) 2016-01-20
US20190337999A1 (en) 2019-11-07
WO2014145368A3 (en) 2014-11-27
RU2015144360A (ru) 2017-04-24

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Application publication date: 20160706