CN105727171A - 一种胆结石药物组合物及其制备方法 - Google Patents

一种胆结石药物组合物及其制备方法 Download PDF

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CN105727171A
CN105727171A CN201610065926.8A CN201610065926A CN105727171A CN 105727171 A CN105727171 A CN 105727171A CN 201610065926 A CN201610065926 A CN 201610065926A CN 105727171 A CN105727171 A CN 105727171A
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李艳梅
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Abstract

本发明公开了一种胆结石药物组合物，按重量份数计包括：金钱草1030份、郁金520份、杜仲515份、枳壳515份、甘草15份、白芍1030份、合欢花520份、龙胆草515份、半夏110份、乳香515份、半枝莲110份、黄芪115份、石韦15份。本发明治疗胆结石的药物组合物，其配方合理，具有舒肝利胆，行气止痛功能，对肝胆内管结石，胆结石病症治疗，排石效果好，见效快，疗程短，无毒副作用。且制备方法简单，便于操作。

Description

一种胆结石药物组合物及其制备方法
技术领域
本发明涉及治疗胆结石领域，特别涉及一种胆结石药物组合物及其制备方法。
背景技术
胆结石又称胆石症，是指胆道系统包括胆囊或胆管内发生结石的疾病；胆道感染是属于常见的疾病。按发病部位分为胆囊炎和胆管炎。结石在胆囊内形成后，可刺激胆囊黏膜，不仅可引起胆囊的慢性炎症，而且当结石嵌顿在胆囊颈部或胆囊管后，还可以引起继发感染，导致胆囊的急性炎症。由于结石对胆囊黏膜的慢性刺激，还可能导致胆囊癌的发生，有报告此种胆囊癌的发生率可达1％～2％。
目前治疗胆结石主要采用手术疗法、碎石疗法、排石疗法，前二种方法起效快，但会复发，后一种方法见效慢，治疗时间长，病人要长期忍受疾病折磨。
公开于该背景技术部分的信息仅仅旨在增加对本发明的总体背景的理解，而不应当被视为承认或以任何形式暗示该信息构成已为本领域一般技术人员所公知的现有技术。
发明内容
本发明的目的在于提供一种胆结石药物组合物，从而克服现有治疗胆结石易复发、效果慢、效果不显著的缺点。
本发明的另一目的在于胆结石药物组合物的制备方法。
为实现上述目的，本发明提供了一种胆结石药物组合物，按重量份数计包括：金钱草10-30份、郁金5-20份、杜仲5-15份、枳壳5-15份、甘草1-5份、白芍10-30份、合欢花5-20份、龙胆草5-15份、半夏1-10份、乳香5-15份、半枝莲1-10份、黄芪1-15份、石韦1-5份。
优选地，上述技术方案中，所述的胆结石药物组合物，按重量份数计包括：金钱草20份、郁金15份、杜仲8份、枳壳9份、甘草3份、白芍20份、合欢花15份、龙胆草11份、半夏6份、乳香9份、半枝莲6份、黄芪11份、石韦3份。
一种胆结石药物组合物的制备方法，包括以下步骤：
(1)称取生产所需的原料；
(2)第一次煎煮，用水浸泡原料药物，然后用武火煎煮至沸后用文火煎煮30～60min，取出药汁，剩余药渣；
(3)第二次煎煮，在所述步骤(2)剩余的药渣中加水进行煎煮，水沸后文火煎煮30～60min，取出药汁，将两次煎煮的药汁合并即可。
优选地，上述技术方案中，所述步骤(2)中的原料药物，加水淹没过药物表面8～10cm，浸泡时间为60～80min。
本发明治疗胆结石药物组合物原料的药性如下：
金钱草：甘、咸，微寒。归肝、胆、肾、膀胱经。清利湿热，通淋，消肿。用于热淋，沙淋，尿涩作痛，黄疸尿赤，痈肿疔疮，毒蛇咬伤；肝胆结石，尿路结石。
郁金：辛、苦，寒。归肝、心、肺经。行气化瘀，清心解郁，利胆退黄。用于经闭痛经,胸腹胀痛、刺痛，热病神昏，癫痫发狂，黄疸尿赤。
杜仲：甘，温。归肝、肾经。补肝肾，强筋骨，安胎。用于肾虚腰痛，筋骨无力，妊娠漏血，胎动不安；高血压。
枳壳：苦、辛、酸，温。归脾、胃经。理气宽中，行滞消胀。用于胸胁气滞，胀满疼痛，食积不化，痰饮内停；胃下垂，脱肛，子官脱垂。
甘草：甘，平。归心、肺、脾、胃经。补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
白芍：苦、酸，微寒。归肝、脾经。平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
合欢花：甘，平；归心、肝经；解郁安神。用于心神不安，忧郁失眠。
龙胆草：味苦，性寒。归肝、胆经。清热燥湿；泻肝定惊。湿热黄疸；小便淋痛；阴肿阴痒；湿热带下；肝胆实火之头胀头痛；目赤肿痛；耳聋耳肿；胁痛口苦；热病惊风抽搐。
半夏：辛，温；有毒。归脾、胃、肺经。燥湿化痰，降逆止呕，消痞散结。用于痰多咳喘，痰饮眩悸，风痰眩晕，痰厥头痛，呕吐反胃，胸脘痞闷，梅核气；生用外治痈肿痰核。姜半夏多用于降逆止呕。
乳香：辛、苦，温。归心、肝、脾经。活血行气止痛，消肿生肌。
半枝莲：苦，寒。清热，解毒。治咽喉肿痛，烫伤，跌打损伤，湿疮。清热解毒。治跌打刀伤出血，汤火伤，咽喉肿痛。
黄芪：甘，温。归肺、脾经。补气固表，利尿托毒，排脓，敛疮生肌。用于气虚乏力，食少便溏，中气下陷，久泻脱肛，便血崩漏，表虚自汗，气虚水肿，痈疽难溃，久溃不敛，血虚痿黄，内热消渴；慢性肾炎蛋白尿，糖尿病。
石韦：石韦，其性味甘、苦，微寒。入肺、膀胱经。有利水通淋、清肺泄热等作用。能清湿热、利尿通淋、治刀伤、烫伤、脱力虚损。
与现有技术相比，本发明具有如下有益效果：本发明治疗胆结石的药物组合物，其配方合理，具有舒肝利胆，行气止痛功能，对肝胆内管结石，胆结石病症治疗，排石效果好，见效快，疗程短，无毒副作用。且制备方法简单，便于操作。
具体实施方式
下面结合具体实施例，对本发明的具体实施方式进行详细描述，但应当理解本发明的保护范围并不受具体实施方式的限制。
实施例1
一种胆结石药物组合物，按重量份数计包括：金钱草20份、郁金15份、杜仲8份、枳壳9份、甘草3份、白芍20份、合欢花15份、龙胆草11份、半夏6份、乳香9份、半枝莲6份、黄芪11份、石韦3份。
一种胆结石药物组合物的制备方法，包括以下步骤：
(1)称取生产所需的原料；
(2)第一次煎煮，用水浸泡原料药物，然后用武火煎煮至沸后用文火煎煮40min，取出药汁，剩余药渣；
(3)第二次煎煮，在所述步骤(2)剩余的药渣中加水进行煎煮，水沸后文火煎煮50min，取出药汁，将两次煎煮的药汁合并即可。
优选地，上述技术方案中，所述步骤(2)中的原料药物，加水淹没过药物表面10cm，浸泡时间为70min。
实施例2
本实施例与实施例1的不同在于，一种胆结石药物组合物，按重量份数计包括：金钱草10份、郁金5份、杜仲5份、枳壳5份、甘草1份、白芍10份、合欢花5份、龙胆草5份、半夏1份、乳香5份、半枝莲1份、黄芪1份、石韦1份。
实施例3
本实施例与实施例1的不同在于，一种胆结石药物组合物，按重量份数计包括：金钱草30份、郁金20份、杜仲15份、枳壳15份、甘草5份、白芍30份、合欢花20份、龙胆草15份、半夏10份、乳香15份、半枝莲1-10份、黄芪15份、石韦5份。
实施例4
本实施例与实施例1的不同在于，一种胆结石药物组合物，按重量份数计包括：金钱草23份、郁金14份、杜仲9份、枳壳8份、甘草3份、白芍18份、合欢花12份、龙胆草11份、半夏7份、乳香12份、半枝莲4份、黄芪12份、石韦3份。
前述对本发明的具体示例性实施方案的描述是为了说明和例证的目的。这些描述并非想将本发明限定为所公开的精确形式，并且很显然，根据上述教导，可以进行很多改变和变化。对示例性实施例进行选择和描述的目的在于解释本发明的特定原理及其实际应用，从而使得本领域的技术人员能够实现并利用本发明的各种不同的示例性实施方案以及各种不同的选择和改变。本发明的范围意在由权利要求书及其等同形式所限定。

Claims (4)

1.一种胆结石药物组合物，其特征在于，按重量份数计包括：金钱草10-30份、郁金5-20份、杜仲5-15份、枳壳5-15份、甘草1-5份、白芍10-30份、合欢花5-20份、龙胆草5-15份、半夏1-10份、乳香5-15份、半枝莲1-10份、黄芪1-15份、石韦1-5份。
2.根据权利要求1所述的胆结石药物组合物，其特征在于，按重量份数计包括：金钱草20份、郁金15份、杜仲8份、枳壳9份、甘草3份、白芍20份、合欢花15份、龙胆草11份、半夏6份、乳香9份、半枝莲6份、黄芪11份、石韦3份。
3.一种根据权利要求1所述的胆结石药物组合物的制备方法，其特征在于，包括以下步骤：
(1)称取生产所需的原料；
(2)第一次煎煮，用水浸泡原料药物，然后用武火煎煮至沸后用文火煎煮30～60min，取出药汁，剩余药渣；
(3)第二次煎煮，在所述步骤(2)剩余的药渣中加水进行煎煮，水沸后文火煎煮30～60min，取出药汁，将两次煎煮的药汁合并即可。
4.根据权利要求3所述的胆结石药物组合物的制备方法，其特征在于，所述步骤(2)中的原料药物，加水淹没过药物表面8～10cm，浸泡时间为60～80min。
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