CN105722984B - 生产包膜病毒的方法 - Google Patents
生产包膜病毒的方法 Download PDFInfo
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- CN105722984B CN105722984B CN201480050980.4A CN201480050980A CN105722984B CN 105722984 B CN105722984 B CN 105722984B CN 201480050980 A CN201480050980 A CN 201480050980A CN 105722984 B CN105722984 B CN 105722984B
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15045—Special targeting system for viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
- C12N2740/15052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1358909 | 2013-09-16 | ||
| FR1358909A FR3010720B1 (fr) | 2013-09-16 | 2013-09-16 | Procede de production de virus enveloppes |
| PCT/FR2014/052279 WO2015036713A1 (fr) | 2013-09-16 | 2014-09-12 | Procede de production de virus enveloppes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105722984A CN105722984A (zh) | 2016-06-29 |
| CN105722984B true CN105722984B (zh) | 2021-08-13 |
Family
ID=50424334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480050980.4A Expired - Fee Related CN105722984B (zh) | 2013-09-16 | 2014-09-12 | 生产包膜病毒的方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10125352B2 (enExample) |
| EP (1) | EP3047025B1 (enExample) |
| JP (1) | JP6629210B2 (enExample) |
| CN (1) | CN105722984B (enExample) |
| CA (1) | CA2923554C (enExample) |
| DK (1) | DK3047025T3 (enExample) |
| ES (1) | ES2732154T3 (enExample) |
| FR (1) | FR3010720B1 (enExample) |
| RU (1) | RU2016114541A (enExample) |
| SG (1) | SG11201602017YA (enExample) |
| WO (1) | WO2015036713A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3014901B1 (fr) | 2013-12-17 | 2017-06-09 | Genethon | Procede de purification de virus ou vecteurs viraux enveloppes |
| KR20180108567A (ko) | 2015-10-22 | 2018-10-04 | 주노 테라퓨틱스 게엠베하 | 형질도입을 위한 방법, 키트, 제제 및 장치 |
| US12037599B2 (en) | 2019-08-23 | 2024-07-16 | Lonza Walkersville, Inc. | Methods and constructs for production of lentiviral vector |
| TW202246517A (zh) | 2021-01-28 | 2022-12-01 | 美商異基因治療有限公司 | 用於轉導免疫細胞之方法 |
| US20250059560A1 (en) * | 2021-12-16 | 2025-02-20 | Sana Biotechnology, Inc. | Methods and systems of particle production |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013076309A1 (en) * | 2011-11-24 | 2013-05-30 | Genethon | Scalable lentiviral vector production system compatible with industrial pharmaceutical applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5110696B2 (ja) | 2004-11-05 | 2012-12-26 | ウェルスタット バイオロジクス コーポレイション | 安定かつ濾過可能なエンベロープで覆われたウイルス処方物 |
| US7875446B2 (en) | 2006-04-20 | 2011-01-25 | Wyeth Llc | Purification processes for isolating purified vesicular stomatitis virus from cell culture |
| DK3192874T3 (da) | 2008-06-18 | 2019-12-16 | Oxford Biomedica Ltd | Virusoprensning |
| US10596264B2 (en) * | 2011-06-30 | 2020-03-24 | Genethon | Peptides with viral infection enhancing properties and their use |
| FR3014901B1 (fr) | 2013-12-17 | 2017-06-09 | Genethon | Procede de purification de virus ou vecteurs viraux enveloppes |
-
2013
- 2013-09-16 FR FR1358909A patent/FR3010720B1/fr not_active Expired - Fee Related
-
2014
- 2014-09-12 JP JP2016542356A patent/JP6629210B2/ja not_active Ceased
- 2014-09-12 ES ES14796166T patent/ES2732154T3/es active Active
- 2014-09-12 EP EP14796166.8A patent/EP3047025B1/fr not_active Revoked
- 2014-09-12 DK DK14796166.8T patent/DK3047025T3/da active
- 2014-09-12 CA CA2923554A patent/CA2923554C/fr not_active Expired - Fee Related
- 2014-09-12 RU RU2016114541A patent/RU2016114541A/ru not_active Application Discontinuation
- 2014-09-12 WO PCT/FR2014/052279 patent/WO2015036713A1/fr not_active Ceased
- 2014-09-12 CN CN201480050980.4A patent/CN105722984B/zh not_active Expired - Fee Related
- 2014-09-12 US US15/022,049 patent/US10125352B2/en not_active Expired - Fee Related
- 2014-09-12 SG SG11201602017YA patent/SG11201602017YA/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013076309A1 (en) * | 2011-11-24 | 2013-05-30 | Genethon | Scalable lentiviral vector production system compatible with industrial pharmaceutical applications |
Non-Patent Citations (2)
| Title |
|---|
| Effects of Culture Parameters on the Production of Retroviral Vectors by a Human Packaging Cell Line;Sally McTaggart et al;《Biotechnol. Prog.》;20000906;第16卷(第5期);摘要,第861页图3 * |
| Transient low pH treatment enhances infection of lentiviral vector pseudotypes with a targeting Sindbis envelope;Kouki Morizono et al;《Virology》;20060814;71–81 * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2732154T3 (es) | 2019-11-20 |
| US10125352B2 (en) | 2018-11-13 |
| CA2923554C (fr) | 2019-10-29 |
| EP3047025A1 (fr) | 2016-07-27 |
| JP6629210B2 (ja) | 2020-01-15 |
| US20160230147A1 (en) | 2016-08-11 |
| CA2923554A1 (fr) | 2015-03-19 |
| WO2015036713A1 (fr) | 2015-03-19 |
| JP2016530890A (ja) | 2016-10-06 |
| CN105722984A (zh) | 2016-06-29 |
| RU2016114541A (ru) | 2017-10-23 |
| EP3047025B1 (fr) | 2019-04-03 |
| SG11201602017YA (en) | 2016-04-28 |
| FR3010720A1 (fr) | 2015-03-20 |
| DK3047025T3 (da) | 2019-06-24 |
| FR3010720B1 (fr) | 2017-08-11 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210813 |